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CLINICAL MANIFESTATIONS OF NON-SPECIFIC INTERSTITIAL
PNEUMONIA
Makhmatmuradova Nargiza Negmatullaevna
Karimov Nodirbek Bakhtiyorovich
Khazratov Bekmurod Sherboevich
Samarkand state medical university, Samarkand, Uzbekistan
https://doi.org/10.5281/zenodo.14631167
Introduction.
In recent years, according to WHO data, many countries
have seen an increase in respiratory diseases, which leads to an increase in not
only disability, but also mortality. An increase in chronic respiratory diseases,
including non-specific interstitial pneumonia, is observed in all countries of the
world [2].
Objective
: to establish clinical manifestations of non-specific interstitial
pneumonia.
Material and methods of research
. As material, we conducted a
retrospective analysis of the case histories of 82 patients with non-specific
interstitial pneumonia, using the necessary volume of clinical research.
Results and discussion
. The obtained results indicate that patients with
nonspecific interstitial pneumonia accounted for about 25% of all patients with
pulmonary pathology who were treated in hospital. The clinical picture was
varied: under the "mask" of acute respiratory disease - 8%, under the "mask" of
acute bronchitis - 13%, under the "mask" of chronic bronchitis - 23%, under the
"mask" of sluggish pneumonia - 27%, under the "mask" of acute pneumonia -
29%. The main clinical manifestations were cough with unproductive sputum -
86%, dyspnea, with minor physical activity - 78%, subfebrile temperature -
41%. Auscultatory data are scarce. Increased bronchial breathing was noted -
75%, weakened vesicular breathing - 64%. Crepitating wheezing - 67%, wet
small and medium bubbling rales - 41%. Laboratory test data: general blood test
- the presence of leukocytosis 9-10 (10 * 9 / l), band shift to the left 15-16%,
accelerated ESR - 14-17 mm / hour. Immunological study of the qualitative
composition of T and B lymphocytes revealed inhibition of the decrease in the
lymphocyte subpopulation - 17-18%. The radiological picture was expressed as
follows: obstructive bronchitis - 47%, hilar pneumonia - 35%, bilateral
pneumonia - 18%. Computed tomography revealed: signs of deforming
bronchitis with pneumofibrosis - 31%, changes of the ground glass type - 37%, a
picture of peribronchial infiltration with focal compaction of lung tissue - 32%.
ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
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Thus, non-specific interstitial pneumonia is characterized by a variety of
clinical course. In this case, the main clinical manifestations of the disease are
cough with sputum, which occurred in 86%, and continuous recurrent course in
34%. Most patients have a decrease in immunity indicators [1].
Conclusions
. The data obtained indicate an increase in patients with non-
specific interstitial pneumonia, with a predominance of dyspnea, weakness,
cough, etc. in the clinic. Clinically, it was manifested by a varied course of the
disease with frequent relapses.
References:
1. Simonova, I.I. On the issue of systemic inflammation in chronic obstructive
pulmonary disease of stable course / I.I. Simonova, M.V. Antonyuk, L.V.
Veremchuk et al. // Health. Medical ecology. Science. - 2016. - Vol. 67, № 4. - pp.
44-54.
2.Balk D.S., Lee C., Schafer J., et al. Lung ultrasound compared to chest X-ray for
diagnosis of pediatric pneumonia: A meta-analysis. //Pediatr Pulmonol. – 2018.
-№53(8). – Р.1130–1139. doi: 10.1002/ppul.24020
