44
остаются достоверно стабильных концентрациях в течение до 7 суток их
использования в инструментальных методах испытаний.
Установлено, что оптимальным сроком хранения образцов слюны,
предназначенной
для испытания биоэлементного состава, составляет в
условиях: лабораторного помещения ‒ до 3
-
х суток; холодильника ‒до 7
-
ми
суток и морозильной камеры ‒ более 7
-
ми суток.
Список литературы
1.
Разакова, Н., Г. Абдиримова, and М. Кодирова. "Влияние воды в
бассейне на pH слюны у детей." Медицина
и
инновации
1.1 (2021): 49-52
2.
Даминова
,
Ш
., et al. "Study of the influence of obesity in parentals on
teething in children of the first year of life who are exclusively breastfeeded." in
Library 22.1 (2022): 86-88.
3.
Хасанова, Л., and М. Юнусходжаева. "О ИЗУЧЕНИИ СОСТОЯНИЯ
ПРОТЕОЛИТИЧЕСКОЙ АКТИВНОСТИ И АНТИПРОТЕАЗНОГО ПОТЕНЦИАЛА
РОТОВОЙ ЖИДКОСТИ У БОЛЬНЫХ С БЫСТРОПРОГРЕССИРУЮЩИМ
ПАРОДОНТИТОМ." Медицина и инновации 1.4 (2021): 509
-512.
4.
Ризаев, Ж., and М. Юнусходжаева. "Биологические основы
остеорепарации и минерального обмена кости При лечении заболеваний
пародонта." Журнал проблемы биологии и медицины 1 (107) (2019): 185
-
188.
5.
Махсумова
I
., Махсумова
S
., Мухамедова
M
., Холматова
Z., &
Маткулиева
S. (2019). Efficacy of treatment of acute herpetic stomatitis. Clinical
and immunological parameters of oral cavity in children. in Library, 19(1), 393
–
395. извлечено от https://inlibrary.uz/index.php/archive/article/view/14504
DYSTROPHIC DISEASES OF THE SALIVARY GLANDS
Jumaev L.R.
Bukhara state medical institute
At the same time, the anatomical and functional identity of the large salivary
glands makes it possible to judge the similarity of pathological changes occurring
in them and to project the results of studies on the group with reactive dystrophic
diseases of the salivary glands as a whole (6,8).
Purpose: to study biochemical parameters in patients with reactive
dystrophic diseases of the salivary glands.
Materials and methods: Determination of the total concentration of oral
fluid glycoproteins was carried out by the method of Romanenko E.G. et al.
(2012). The fucose content in oral fluid glycoproteins was determined by the
reaction of Dishe and Shettles (Dische Z., 1948). The concentration of
hexosamines was determined by the method of Elson and Morgan (Elson L.,
Morgan W., 1933). The concentration of sialic acid was determined using 2-
thiobarbiturate acid (L. Warren, 1959). Determination of the amount of total
45
protein in the oral fluid was carried out by the method of Lowry O.H. (1951). The
results were recalculated per 1 ml of oral fluid volume, taking into account the
dilution of samples during hydrolysis.
Results and discussion/Monosaccharides in glycoproteins can be galactose,
glucosamine, galactosamine, fucose, sialic acid. These monosaccharides
associated with the protein change the biochemical and immunological
properties of the protein, its spatial configuration. Sialoglycoproteins determine
an increase in the life span of the protein in biological fluids.
Consequently, a high level of sialic acids in the glycoproteins of the oral fluid
can be a compensatory device that ensures the viscosity of the oral fluid, which in
physiological conditions and especially during physical exertion provides the
barrier function of saliva. An increase in the hydrophobicity of the oral fluid
associated with an increased content of fucose indicates, on the one hand, the
viscosity of saliva in response to physical exertion, on the other hand, the
synthesis of hydrophobic gastric mucus.
Conclusion
These violations were of an age-dependent nature. It was found that a
chronic dystrophic process was observed in the div of patients, and its
manifestations were noted already in the first age group. In patients of the older
age group, obviously, due to a long-term violation of the processes of nutrition
and digestion caused by pathological changes, metabolic disorders were more
pronounced than in patients of the younger group. At the same time, the
mechanism responsible for the formation of the structure of the organic
components of the connective tissue matrix was disrupted to a greater extent in
the latter, which was manifested to varying degrees by the disorganization of the
collagen and non-fibrillar structures of the matrix included in it.
The study of laboratory parameters can be used to evaluate the
effectiveness of treatment of patients with reactive-destructive diseases of the
salivary glands and to conduct a retrospective analysis.
References
1.
Исаходжаева, Х.,
et al
. "ВЛИЯНИЕ ГЕСТАЦИОННОГО ВОЗРАСТА И
МАССЫ
ТЕЛА
НОВОРОЖДЕННОГО
НА
ПРОРЕЗЫВАНИЕ
ЗУБОВ."
Stomatologiya 1.1 (82) (2021): 40-42.
2.
Разакова, Н., Г. Абдиримова,
and
М. Кодирова. "Влияние воды в
бассейне на
pH
слюны у детей." Медицина и инновации 1.1 (2021): 49
-52.
3.
Исаходжаева, Х.,
et al
. "ВЛИЯНИЕ ГЕСТАЦИОННОГО ВОЗРАСТА И
МАССЫ
ТЕЛА
НОВОРОЖДЕННОГО
НА
ПРОРЕЗЫВАНИЕ
ЗУБОВ."
Stomatologiya 1.1 (82) (2021): 40-42.
4.
Даминова, Ш., et al. "Study of the influence of obesi
ty in parentals on
teething in children of the first year of life who are exclusively breastfeeded." in
Library 22.1 (2022): 86-88.
5.
Ризаев, Ж.,
and
М. Юнусходжаева. "Биологические основы
остеорепарации и минерального обмена кости При лечении заболеваний
46
пародонта." Журнал проблемы биологии и медицины 1 (107) (2019): 185
-
188
6.
Хасанова, Л.,
and
М. Юнусходжаева. "О ИЗУЧЕНИИ СОСТОЯНИЯ
ПРОТЕОЛИТИЧЕСКОЙ АКТИВНОСТИ И АНТИПРОТЕАЗНОГО ПОТЕНЦИАЛА
РОТОВОЙ ЖИДКОСТИ У БОЛЬНЫХ С БЫСТРОПРОГРЕССИРУЮЩИМ
ПАРОДОНТИТОМ." Медицина и инновации 1.4 (2021): 509
-512.
