IN VITRO SCREENING OF PARANGI RASAYANAM, A SIDDHA DRUG, FOR ITS ANTIFUNGAL PROPERTY

Abstract

The aim of this study was to evaluate the antifungal property of Parangi Rasayanam, a Siddha drug, through in vitro screening. Parangi Rasayanam is a traditional herbal formulation used in Siddha medicine, a system of traditional medicine practiced in South India. Fungal infections pose a significant health burden, and alternative treatments are sought to combat drug-resistant strains. In this study, Parangi Rasayanam was subjected to in vitro testing against a panel of clinically relevant fungal strains. The findings demonstrate the potential antifungal activity of Parangi Rasayanam and provide a basis for further investigation and development of this Siddha drug as a therapeutic agent. Parangi Rasayanam is a traditional Siddha drug formulation used in South India, known for its medicinal properties. In this study, we aimed to evaluate the antifungal property of Parangi Rasayanam through in vitro screening against clinically relevant fungal strains. Standard methods such as agar disk diffusion and broth microdilution assays were employed to assess the inhibitory activity of Parangi Rasayanam. Our findings demonstrated significant antifungal activity of Parangi Rasayanam against a range of fungal strains, including Candida albicans, Aspergillus fumigatus, and Trichophyton rubrum. These results support the traditional claims of Parangi Rasayanam's antifungal potential and highlight its potential as an alternative treatment for fungal infections. Further studies are warranted to elucidate the active constituents and mechanisms of action of Parangi Rasayanam and to assess its efficacy and safety in clinical settings. The development of Parangi Rasayanam as an antifungal therapeutic agent holds promise in combating drug-resistant fungal infections.