DEVELOPMENT OF A MEDICINAL PHYTOPARD PRESERVATIVE DENTAL  POLYMER WITH A MODERATE COMPOSITION OF MOTHER OF PEARL  (MATRICARIA, CHAMOMILLA) DRY EXTRACT

M Ishmukhamedova; G Islamova

63

Volume 5, Issue 10: Special Issue
(EJAR)

ISSN: 2181-2020

MPHAPP

THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL

CONFERENCE

“

MODERN PHARMACEUTICS: ACTUAL

PROBLEMS AND PROSPECTS

”

TASHKENT, OCTOBER 17, 2025

in-academy.uz

DEVELOPMENT OF A MEDICINAL PHYTOPARD PRESERVATIVE DENTAL

POLYMER WITH A MODERATE COMPOSITION OF MOTHER OF PEARL

(MATRICARIA, CHAMOMILLA) DRY EXTRACT

Ishmukhamedova M.A.

1

Islamova G.P.

2

Tashkent Pharmaceutical Institute, Tashkent city, Republic of Uzbekistan

e-mail: muattarIa@gmail.com

https://doi.org/10.5281/zenodo.17318423

Relevance:

An analysis of the literature on the chemical composition, medicinal properties and

use of the chamomile plant in medicine, in particular in dentistry, was carried out. Studies show that
flavonoids, chamazulene, apigenin, essential oils and other biologically active substances contained
in chamomile extract have anti-inflammatory, antiseptic, analgesic and regenerating effects.

In dental practice, chamomile extract is widely used in the treatment of inflammation of the

oral mucosa (gingivitis, stomatitis, periodontitis, etc.). Medicines prepared on the basis of this extract
help maintain oral hygiene, reduce microbes, and restore the mucous membrane.

Based on the literature studied, it was determined that the creation of coatings that can be used

in dentistry based on chamomile extract is of scientific and practical importance.

Objective. Taking into account the above, the aim of the study was to justify the moderate

composition of a dental polymer medicinal phytopar containing chamomile dry extract obtained from
a local chamomile plant.

Methods and styles.

In our studies, initially, the concentration of chamomile dry extract was

selected as 10% in the polymer mass based on scientific articles. At the next stage, a polymer that
forms a moderate coating was selected to create a polymer medicinal coating. For this, model polymer
masses were formed using various polymers. Na KMS, MS, collagen, PVP were used as polymers in
the formation of the film. Of these, MS polymer was selected as moderate.

Initially, the effect of the concentration of glycerin added as a plasticizer on the properties of

medicinal polymer films was studied. The following indicators were evaluated: appearance and
ability to separate from the mold surface:

The analyses were carried out in accordance with the methods given in the State Pharmacopoeia

of the Russian Federation, as well as the State Pharmacopoeia of the Republic of Uzbekistan and
literature sources. At the next stage, the effect of the concentration of peach oil added to the mass of
medicinal polymer film on the properties of the above-mentioned polymer films was also studied

Results.

For the study, glycerin was added in concentrations of 1.0%, 1.5%, 2% and evaluated

according to the above-mentioned indicators. The best result according to the above-mentioned
indicators was recorded for the medicinal polymer film containing 2% glycerin. Since the desired
viscosity was not achieved after the addition of glycerin as a plasticizer, the next step was to examine
the effect of peach oil on the properties of the medicinal polymer film. For this, medicinal polymer
films with peach oil added at concentrations of 0.5%, 1%, and 2% were prepared. When studying the
properties of the obtained polymer films, it was found that the moderate concentration was 2%. At
the remaining concentrations, brittleness of the film was noted. According to the experimental results,
MS was selected at a concentration of 2% as the moderate polymer forming the film in the
composition of the dental polymer film based on chamomile dry extract.

Conclusion.

A number of polymers were studied to obtain dental polymer medicinal phytofilms

containing chamomile dry extract: Na KMS, MS, collagen, PVP. According to the results of

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