169
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
STUDY OF THE RHEOLOGY OF THE PASTE “UROKONIT
-
MR”
M.M.Rakhmatullayeva
Tashkent Pharmaceutical Institute, Tashkent, Republic of Uzbekistan
е
-mail: farmi69@mail.ru
https://doi.org/10.5281/zenodo.17328806
Relevance:
Kidney and urinary system diseases of various etiologies occupy an important place
in the general structure of the population's morbidity. Along with synthetic drugs, herbal preparations
are also widely used for their treatment. An extract was obtained on the basis of hairy erva grass,
nettle leaves, common goldenrod, bird's foot, cornflower mouth and column, onion peel, Silica-
Horsetail-equisetum arvense, birch leaves. Glycerin, wheat starch, vanillin, monodistilled fatty acids
(emulsifier E 471) were used as excipients. "Uroconit-MR" paste was prepared.
The purpose of the study:
to study the rheological properties of the paste "UROKONIT-MR".
Methods and techniques:
The experiments were carried out on the Reotest-2 device using a
cell consisting of a system of S/S
1
cylinders with a Z( (constant) = 5.8.
The indicator of the device was carried out in mode 1 (at 25, 40, 55
o
C) at a constant temperature
of different numbers. Before performing the experiment, the paste was thoroughly mixed so that there
were no voids and bubbles in the paste. The paste was placed in special glass jars and thermostated
at a specified temperature (25, 40, 55
o
C) ± 2
o
C for 2 hours. The saturated shear stress of the system
τ =
·Z, gradient velocity (γ), effective viscosity (η) and logarithm of effective viscosity were
determined.
Results:
The saturated shear stress (τ = a•Z), gradient velocity (γ), effective viscosity of the
“UROKONIT-MR” paste at different temperatures The results of the logarithm of (η) and effective
viscosity are presented in the table.
As can be seen from the table, the shear stress decreases sharply with increasing temperature.
This indicates that the activation energy of viscous flow decreases, and as a result, the effective
viscosity also decreases. When the gradient velocity is small, the viscosity is high, and when the
temperature increases from 250С to 550С, its value decreases. Therefore, the structure of the system
is destroyed. As the velocity gradient increases, the viscosity decreases to a minimum, that is, the
structure of the paste is completely destroyed.
Conclusions: In the process of studying the rheological properties of the paste, the saturated
shear stress, gradient velocity, effective viscosity and logarithm of effective viscosity at different
Асбоб
кўрсаткичи
Siljishi kuchlanishi ,
=
*Z, Pа
Tezligi gradienti,
, с
-1
Effektiv qovushqoqlik ,
η
eff
. =
/
, Pа.с
Effektiv qovushqoqlik logarifmi,
lnη
eff
., Pа.с
№
α
25
о
С
40
о
С
55
о
С
25
о
С
40
о
С
55
о
С
25
о
С
40
о
С
55
о
С
25
о
С
40
о
С
55
о
С
1а
8
46,4
11,6
5,8
3,0
3,0
3,0
15,4
3,8
1,9
2,73
1,33
0,64
2а
8
46,4
17,4
5,8
5,4
5,4
5,4
8,59
3,2
1,07
2,15
1,16
0,06
3а
9
52,2
17,4
5,8
9,0
9,0
9,0
5,8
1,9
0,64
1,75
0,64
-0,44
4а
10
58
23,2
11,6
16,2
16,2
16,2
3,58
1,43
0,71
1,27
0,35
-0,34
5а
13
75,4
23,2
11,6
27,0
27,0
27,0
2,79
0,85
0,42
1,02
-0,16
-0,86
6а
16
92,8
29
11,6
48,6
48,6
48,6
1,9
0,59
0,23
0,64
-0,52
-1,46
7а
20
116
29
17,4
81,0
81,0
81,0
1,4
0,35
0,21
0,33
-1,04
-1,56
8а
28
162,4
46,4
17,4
145,8
145,8
145,8
1,1
0,31
0,11
0,09
-1,17
-2,20
9а
41
237,8
75,4
23,2
243
243
243
0,97
0,31
0,09
-0,03
-1,17
-2,4
10а
54
313,2
139,2
46
437,4
437,4
437,4
0,71
0,31
0,09
-0,34
-1,17
-2,4
11а
67
388,6
243,6
69,6
729
729
729
0,53
0,33
0,09
-0,63
-1,1
-2,4
12а
84
487,2
440,8
116
1312
1312
1312
0,37
0,33
0,08
-0,99
-1,1
-2,52
170
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
temperatures were determined. Analysis of the results obtained showed that "Uroconit-MR" is a
system that does not obey Newton's law.
