525
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
ASTAXANTHIN AS AN INNOVATIVE ANTIOXIDANT: CREATION AND STUDY
OF SERUM WITH HAEMATOCOCCUS PLUVIALIS EXTRACT
Yesimkhan Zh.K.
Alimova U.S.
JSC "Kazakh National Medical University named after S.D. Asfendiyarov"
Almaty, Republic of Kazakhstan
tel.: +77770651004, e-mail: esimhan.zhibek@yandex.ru
https://doi.org/10.5281/zenodo.17343961
Relevance:
Interest in natural antioxidants is growing in cosmetology. Astaxanthin from the
microalgae
Haematococcus pluvialis
is more active than many known antioxidants and can protect
the skin from photoaging and oxidative stress. Research into the development of stable and safe
formulas is needed to incorporate it into cosmetics.
Objective:
To develop the composition of serum with
Haematococcus pluvialis extract
and to
evaluate its safety and stability.
Methods:
The serum was developed taking into account the physicochemical properties of
astaxanthin. The extract was standardized for its active ingredient content, and safety and storage
stability testing were conducted.
Results:
A serum formulation was developed with a uniform distribution of
Haematococcus
pluvialis extract
, containing the biologically active carotenoid astaxanthin. The included auxiliary
components ensured optimal consistency, ease of application, and preservation of the active
ingredient.
Conducted studies have shown no irritating or sensitizing effects, confirming the product's
safety for various skin types, including sensitive skin. Clinical studies have demonstrated good
tolerability and a comfortable sensation after use.
The samples remained stable for several months under standard storage conditions: no changes
in color, odor, viscosity, precipitation, or loss of active ingredient activity were observed. This
demonstrates the reliability of the developed formula and its technological stability.
Conclusions:
The serum with
Haematococcus pluvialis extract
possesses pronounced
antioxidant potential, making it a promising treatment for preventing photoaging and protecting skin
from the negative effects of environmental factors. The results confirm the safety, stability, and
efficacy of the proposed composition, opening the door to further in-depth clinical trials and
commercialization.
