552
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
DEVELOPMENT OF AN EFFERVESCENT TABLET FORM FOR BATHS WITH
SOOTHING AND ANTI-INFLAMMATORY EFFECT BASED ON NATURAL RAW
MATERIALS
Shaizanda A.B.
Umirzakova U.N.
Torlanova B.O.
South Kazakhstan Medical Academy, Shymkent, Kazakhstan
e-mail: shayzanda.ayaulym_skma@mail.ru
https://doi.org/10.5281/zenodo.17344229
Relevance
: In recent decades, there has been a steady increase in the incidence of skin
pathologies — allergic dermatitis, eczema, psoriasis, as well as various forms of skin irritation caused
by adverse environmental conditions, stress, and reduced immunity. According to dermatological
practice, up to 20–30% of the population of different age groups experience manifestations of skin
hypersensitivity, accompanied by itching, inflammation, and impaired barrier function. Existing
dosage forms (ointments, alcohol-based solutions, creams) have limitations: they may cause burning
and discomfort, make it difficult to apply evenly over large skin areas, and reduce treatment
adherence. In this regard, there is growing interest in remedies based on natural plant and mineral raw
materials, which are characterized by mild action, ecological safety, and ease of use.
Objective:
To develop an effervescent tablet form for baths, providing soothing, anti-
inflammatory, and softening effects for sensitive skin.
Materials and Methods:
The active components included licorice extract, oat powder, sea salt,
kaolin, and lavender essential oil. The effervescent base consisted of citric acid and sodium
bicarbonate, while starch and sorbitol were used as excipients. Laboratory studies were carried out to
select the optimal ratio of acid and bicarbonate, which showed that upon tablet dissolution, the
reaction proceeded completely, and the resulting solution had a pH of 6.5–7.0, corresponding to the
physiological level of the skin. This confirmed the absence of irritating effects on damaged areas.
Additionally, organoleptic properties, dissolution rate, and stability of the obtained tablets were
evaluated. The results demonstrated that all included ingredients are not only safe but also possess
beneficial dermatoprotective properties: reducing itching and inflammation, promoting hydration,
and providing gentle skin cleansing.
Results:
Laboratory tests established that the effervescent base (citric acid and sodium
bicarbonate) at the optimal ratio is fully neutralized, producing a solution with pH 6.5–7.0, safe for
damaged skin. The active components (licorice, oats, sea salt, kaolin, lavender) confirmed their
dermatoprotective properties: relieving itching, reducing inflammation, gentle cleansing, and skin
mineralization. The developed form demonstrated safety, stability, and promising potential as a
preventive skincare product.
Conclusion:
The development of effervescent bath tablets based on natural raw materials
represents a promising direction in pharmaceutical technology. The product may be used for
prevention and comprehensive care in cases of allergies, dermatitis, and skin hypersensitivity across
different age groups.
