Natural Sciences

Currently, the recycling of worn-out car tires is a serious problem. For example, world statistics on tire recycling showed the formation of more than 14.5 million tons of depreciated car tires per year. However, about 10% of used tires are recycled. Tire recycling by pyrolysis makes it possible to obtain fuels and lubricants, and the chamber residue represented by carbon often poses a threat to the environment as a pollutant. Therefore, the disposal of the resulting carbon black is a major problem. At the Navoi State University of Mining and Technology at the Department of Chemical Technology, the physico-mechanical properties of a carbon-saving material, which is a secondary raw material for the production of pyrolysis of worn tires, were analyzed, in turn, and the technological parameters of rubber mixtures based on SKI-3 and Nairit KR-50 rubbers were studied.

Oxidation-reduction processes are phenomena that occur continuously in nature. As a result of these processes, organic substances are converted into inorganic ones. Energy exchange in living organisms, thermal phenomena in physics, and electrical processes in nature are also related to oxidation-reduction processes. The essence of these processes is that the oxidation state of the particles that make up the substance changes during chemical reactions. This topic is mainly studied in depth in chemistry. This article provides valuable information on teaching oxidation-reduction processes.

XXI asr - texnologiyalar asri hisoblanadi. Shunday ekan o‘quv jarayonida turli zamonaviy axborot vositalaridan o‘rinli foydalanish, kompyuterli ta’lim jarayonida darslarni o‘quvchi-talaba va kompyuter orasidagi munosabatlarga ko‘ra tashkil etish, boshqarish, nazorat qilish bugungi kunda dolzarb masalalardandir.Tabiiy fanlar hamda texnika fanlarida uchraydigan ko‘pgina masalalar differensial tenglamalarga keltiriladi,ya’ni ularning analitik yechimini topish nihoyatda murakkab masala,shu sababli taqribiy yechish usullaridan foydalanish ko‘proq samara beradi.Bunday muammolarni hal qilish uchun esa matematik paketlar mavjud bo‘lib,ushbu maqolada differensial tenglamalarni Maple dasturida yechish haqida gap boradi.Ya’ni, birinchi tartibli chiziqli oddiy differensial tenglamani Maple dasturida analitik yechimini topish dasturi tuzilib natija olingan.

Subject of the research: this research’s object is government’s politics on social development in the villages of Uzbekistan’s southern regions during Uzbekistan’s Independence.
Purpose of work: Uzbekistan’s social politics in the villages of southern regions during Indcrcndcnce and accomplished practical works on cultural spheres. Analyzing their results and making conclusions.
Methods of research: while carrying out this research following characters were in use: historicalness, scientific impartiality, running collected materials, historical-comparative analyses.
The results achieved and their novelty: in the Kashkadarya and Surkhandarya (1991-2008) regions’ social and cultural state, appeared complications in this field, oppositions, and social living conditions learned, analyzed and sufficient conclusions implemented.
Practical value: dissertation information and conclusions could be applicable to do research on Uzbekistan’s history science problems, upbringing generation in a patriotic manner, epistle, and monograph in Uzbekistan’s history science and to write textbooks and learning method manuals.
Degree of embed and economic effectivity: the dissertation’s main content emphasized and reflected bu the author the dissertation, they arc: 4 printed scientific articles, 1 methodical handbook, and 7 attended conferences.
Field of application: the research attainments give the opportunity to use the research achievements to establish information about studying Uzbekistan’s Indcrcndcnce period, printing, and providing.

The aim of the research work is concluded obtaining novel tupe of stimulants based on synthesis homogeneous and mixed ligand coordination compounds of calcium and magnesium sucsinate with organic ligands.
Scientific novelty of the research work is as follows:
there have been revealed the synthesis condition, structure and individuality of 61 homogeneous and mixed ligand coordination compounds of calcium and magnesium sucsinates;
there have been proved the coordination propecties of amide, acetic ligand fragments by adsorption of infrared spectroscopy and quantium chemical analysis, as well as it has been shown the structure of some types of compounds;
it was revealed that dependence of specificities of structure, property and composition of sucsinate groups in the compounds from nature of complex-former, organic ligand and coordination ability;
there have been revealed the factors determining particular coordination ability of amides, sucsinatic fragments;
there have been created the stimulants for acceleration of the growth and rising of agriculture crops;

The aim of research work is synthesis of fluorinated polydentant ligands and their complexes with ions of Ni(II) and Cu(II), and determination of structures and properties.
Scientific novelty of the research is as follows:
The new 27 organic ligands and 44 intercomplex compounds on their base were synthesized for the first time;
single crystals of 6 ligands and 4 complexes were grown, their molecular and crystal structures were determined;
method of synthesis of fluorinated P-diketones by Lil I was developed for the first time;
systematic data about regio-oriented reactions of fluorinated 1,3-diketones with acylhydrasines and structural factors for obtaining some individual regioisomers were determined;
it was determined that central ion of 3d-metals in chelat compounds and double deprotonated residues of ligands form five and six-membered metallocycles;
formation of a d-n-dative bound between d-electrons of nickel and cupper atoms with я-orbitals of a monodentant Py ligand was proved.

The actuality and claiming of the theme of dissertation. Currently in the world selecting medical components from plants and getting a new medical components on their basis is 50-60%. Gossypol obtained from cotton can also be attributed to such medical drugs which efficiency of interferon inductors was shown at some viral diseases (ARVI, influenza, herpes virus infection, hepatitis and others).
Since the acquisition of independence of our republic large-scale activities on the creation of scientific research at a high level on the development of the creation of medicines on the basis of local raw materials and the supplying with quality drugs a pharmacy national market have been carried out and appropriate results have been achieved. It can be highlighted the drugs (mcgocin, ragocin, kagocel, gozalidon and etc.) obtained from gossypol derived from local raw materials against viral diseases.
Nowadays synthesizing new components of gossypol, identifying its biologic activity and creating drugs against diseases of immunity arc considered as the urgent tasks in the world. Moreover, preventing infectious pathology on the base of gossypol and synthesizing amino-compounds of alkaloids for producing drugs on carrying out research for producing therapeutic drugs, creating effective machinery in synthesizing herbal matters, identifying the construction, products and features of synthesized compounds with the help of modem physic-chemistry methods, decreased the poisonous effect with the help of modifying the gossypol with other various substances intensifying the activity against fungi and identifying the activity of gossypol products against dangerous swellings and others arc considered as the urgent tasks.
The research of this dissertation in a sense is devoted to fulfilling the tasks which were outlined in the decree of President of Uzbekistan Republic № 416 from 14.07.2006 «Objectives on supporting the manufacturers producing local medicine and medical equipment», and the decree № 1442 from 15.12.2010 «Prime ways on the development of manufacture of Uzbekistan Republic during 2011-2015 years», and in other documents concerning to this field.
The aim of research work is purposeful modification of gossypol molecules and its structural analogies, investigation of biological activity and determination of physic-chemical properties of synthesized compounds.
Scientific novelty of the research work is as follows:
formation of free radicals in cotton has been investigated and also more then 100 new azomcthinc derivatives of gossypol, 2-oxybcnzaldchyde, 2-oxynaphtaldchydc and pyrridoxalc and also compounds containing hydrazine like pharmakophiric group (derivatives of ephedrine, salsolinc, carbazol and diphcnylaminc) have been synthesized;
anti-virus activity of new derivatives of gossypol against virus stomatite (VVS) was shown and at this height antivirus active for thrcptophanc compounds was determined and also compounds possessing by high biological activity again bacterium's - E.coli, St.aureus, X.malvasearum, B.subtilis and some others has been determined;
supramolecular and metal- complexes (on the base of salts containing ions of metals Cu2+, Ni2+) of Schiff bases of gossypol have been obtained. On the base of investigation of UV-, IR-, PMR- and mass-spectrums of obtained compounds their structure was confirmed;
diaminogossypol was synthesized by two methods; on its base were obtained Schiff bases with aldehydes of different nature; with using of gaunt-chemical calculations, their molecular-dynamical constants and electronical structure were determined;
it proved greater intcrfcron-inducing activity of supramolecular complexes mcgosin and tagosin with MASGA relatively gossypol, mcgosin and tagosin;
HPLC method was developed to identify, and quantify the separation of content and mcgosin MASGA in mcgafcrone defined supramolecular complex composition and the degree mcgafcron crystallinity substances.
CONCLUSION
On the basis of conducted research for his doctoral thesis on «Synthesis, structure and biological activity of novel derivatives of gossypol» presented the following conclusions:
1. The studies synthesized new azomethine derivatives of gossypol, 2-hydroxybcnzaldehyde, 2-oksinaftaldcgida and pyridoxal, diaminogossipol and on its basis a new Schiff base, this will in the long term for drugs based on local raw materials.
2. Revealed that the composition of cotton, in various conditions free radicals arc formed, it is proved that the formation of free radicals occurs at temperatures above 30°C due to the decomposition of dissolved O2 in lipid complexes, in the future it will serve to improve the development of new drugs have representatives have fungicidal properties the importance of agriculture.
3. A systematic analysis of activity against bacteria and fungi (E.soli, St.aurcus, V.dahliae, F.ohusrorum, R.solani, X.malvascarum, S.cerevisiae, C.scotti, C. albicans and B. subtilis ) synthesized compounds, the results obtained will hereinafter important when developing new drugs having antibiotic properties.
4. Installed Activity supramolecular complexes mcgosin and tagosin with MASGA to peritoneal fluids number of macrophage cells, it gives the opportunity to create products with higher interferon inducers based mcgafcron.
5. Biological activity of some derivatives gossypol PASS calculated by the program, and the data obtained showed identical results with the experimental methods of performing various pre calculation using computer programs subsequently result in savings of expensive reagents.
6. With the help of special programs of computer package designed power growth dynamics of the formation of the synthesized complexes with the growing number of GA molecules, low probability of consolidation of clusters, it is predicted that, in real systems the number of GA associates can make n = 2-4.
7. The crystal structure was studied clathrates gossypols Schiff bases with o-toluidinc and p-xylidine, it was found that the reaction of 1,4-dioxanc with Schiff bases molecules occurs by hydrogen bonds, these data allow to obtain different clathrates using various solvents.
8. For the first time developed a method of identifying and separating mcgosinc and MASGA in mcgafcronc by HPLC. Quantitative data processed by statistical methods. The data in the future will serve to study the quantitative composition of supramolecular drugs.

The aim of the study is a targeted synthesis of soluble and water-insoluble polymers having carboxyl groups in the structure, establishing their physicochemical, medical-biological properties and processes of interaction with low-molecular compounds, and the obtaining of an antiprotozoal preparation on their basis.
The scientific novelty of the research is as follows:
for the first time the complexes of PMAC and imidocarb-dipropionate of 3,3-bis (2-imidazolinyl-2) -carbanilide were synthesized;
for the first time, the possibility of a first-order phase transition of PMAC macromolecules in the form of polymer complexes in the interaction of highly concentrated solutions of PMAC and imidocarb was established;
the preservation of the chemical structure of the imidocarb by means of cooperative binding during its immobilization at PMAC has been demonstrated;
for the first time on the basis of polymeric complexes PMAC and imidocarb developed a little toxic and prolonged antiprotozoal dosage form;
for the first time, granular sorbents were obtained by modification of PVC amino-acetic, aminocaproic, o-, m-, p-aminobenzoic acids;
the effect of the steric effect of neighboring functional groups, besides the basicity of the amino group, on the modification of PVC by amino acids, has been proved;
the regression equations for the reactions of modifications of PVC with aminoacid and m-aminobenzoic acid have been calculated;
the strong influence of the solvent on the process of modification of PVC by amino acids and the amorphous structure of the obtained samples were established.

Topicality and demand of the subject of dissertation. As a result of consecutive realization of the program of priority development of the industry accepted in the Republic for 2011-2015 and branch programs on modernization, technical and technological updating of production in the structure of industry the processing sectors play more important role, manufacturing competitive productions with high additional costs.
Thus, the special attention is given to the problem of localization, creation and introduction of the new biologically active compounds used in various areas of the national economy that leads to an import substitution and saving of currency resources.
Along with increase in volume of manufacturing chemical products the important task of the further expansion of their assortment and improvement of quality has been put.
The main role in this aspect belongs to direct searches of new valuable substances, more effective methods and processes of synthesis and division of products, and the ways of radical improvement of existing manufactures.
There is a tendency to creation of the processes using cheaper local raw materials at the minimal expenses of the other reagents.
Development of new technology more and more is based on its scientific evidence, including knowledge of the mechanism and physical and chemical laws of the process. Greater reserves in increase of the production efficiency are available in the field of improvement of the operating enterprises with a choice of the best parameters of the process, modernization of technological schemes and the equipment, and qualified use of by-products and production wastes. In the conditions of an economic reform being carried out in our Republic the set of all these factors gets special importance for the further development of the organic synthesis industry.
Aromatic keto- and carboxylic acids represent special interest for the synthesis of potential medical products, plant growth stimulants, plasticizers, synthetic lubricant oils, dyes in the development of our industry due to the presence of highly reactive carbonyl (C=O) and carboxyl (COOH) groups in their structures.
According to the President of the Republic Uzbekistan Decrees N272 issued on January 31, 2006 «About measures on improvement of plans of agricultural plants protection and the system of measures on supplying with chemical preparations», N731 from November 19, 2007 «About the program of modernization, technical and technological reequipment of the pharmaceutical plants for the period till 2011», and N1442 from December 15, 2010 «About priorities of development of the industry of the Republic of Uzbekistan in 2011-2015» development to biological active compounds and their application into industry.
On the basis of carried out works on the synthesis of aromatic кето- and carboxylic acids the conditions of the synthesis of substances with various functional groups, having a wide spectrum of biological actions will be developed.
In this connection creation of scientific bases for obtaining of aromatic keto- and carboxylic acids by oxidation of aromatic hydrocarbons and the solution of the problems related to the synthesis of biologically active substances on their basis is the actual task representing both theoretical and practical value.
The substances with high plant growth stimulating effect that increase the productivity of plants and anti-inflammatory activity on living organisms with little harmful actions found as a result of researches carried out in last years on the synthesis of aromatic keto- and carboxylic acids shows the urgency of the chosen theme.
The collected data on the synthesis of new aromatic кето- and carboxylic acids, their derivatives, physico-chemical and biological properties, and also the results of implementation of new preparations into manufacture can be effectively used in this area of the research.
Purpose of research is development of theoretical and practical bases of synthesis of aromatic keto- and carboxylic acids by oxidation of alkylbenzenes and solving practical problems related to the synthesis, and application of biologically active substances on their basis.
Scientific novelty of disscrtational research consists in the following:
by oxidation of 1.3- and 1,4-diethylbenzenes and methylethylbenzenes with the solution of potassium permanganate was found the optimum conditions, allowing to obtain the maximum output of 1,3- and 1,4-benzenemono-ketodicarboxylic and also 1,3- and 1,4-benzenediketodicarboxylic acids, and from the obtained reaction mixture the indicated acids were isolated in individual state for the first time;
carbonyl group derivatives - phenylhydrazones, semicarbazones, thiosemicarbazones, quinoxalones, and disulfide derivatives as well as carboxyl group derivatives - ethers, salts (altogether 45 compounds) were synthesized on the basis of 1,3- and 1,4-benzenemonoketodicarboxylic, and 1,3- and 1,4-benzenediketodicarboxylic acids;
structural, stability and reactivity features of the synthesized compounds with their pharmacological and growth-stimulant activities were investigated;
for the first time, on the basis of 1,3- and 1,4-benzeneketodicarboxylic acids mixtures growth stimulant preparations of ketostim and ketostim-K. were synthesized;
etherification process of 2,4-dichlorobenzoic acid with 2-butynediol-l,4 and the condensation of obtained l,4-bis-(2,4-dichlorobenzoyloxy)-butyne-2 with phenylazide have been investigated. In etherification stage of 2,4-dichlorobenzoic acid with 2-butynediol-l,4 along with bis-ether (l,4-bis-(2,4-dichlorobenzoyloxy)-butyne-2) a mono-ether (2,4-dichlorobenzoyloxybutyne-2-ol-4) was also found to be formed. Separation and purification methods of obtained mono- and bis-ethers have been developed. l-phenyl-4,5-bis-(2,4-dichlorobenzoyloxymethyl)-1,2,3-triazol (dichlotazol preparation) was synthesized by condensation from the obtained bis-ether with phenylazide, and l-phenyl-4-(2,4-dichlorobenzoyloxy-methyl)-5-carbinol-l,2,3-triazol (monochlotazol preparation) from mono-ether, which showed high anti-inflammatory activity;
from them, a substance of a dichlotazol preparation and its medicinal form in 3% ointment was recommended for the treatment of an inflammation of genitals in medicine and the technologies of their obtaining were developed.
CONCLUSION
1. As a result of oxidation research of 1,3- and 1,4-diethylbenzenes and their mixture, 1,3- and 1,4-methylethylbenzenes, 1,2,3,5-and 1,2,4,5-tetraethylbenzenes by potassium permanganate solutions in an alkaline medium were revealed regularity of the process depending on temperature, concentration of an oxidizer, duration on a final yield of benzeneketocarboxylic acids.
2. It was found that oxidation of diethylbenzenes to benzenedicarboxylic acids goes through the formation of benzenediketodicarboxylic and benzenemonoketodicarboxylic acids. In case of oxidation of tetraethylbenzenes the mixture of benzenetetraketotetracarboxylic, benzenetriketotetracarboxylic, benzenediketotetracarboxylic, benzenemonoketotetracarboxylic and benzenetetracarboxylic acids are formed.
3. Methods of separation of the mixture of benzeneketodicarboxylic acids were developed and the individual isomers of 1,3- and 1,4-benzenemonoketodicarboxylic, 1,3- and 1,4-benzenediketodicarboxylic acids were isolated for the first time from the products of dialkilbenzenes oxidation. Physical and chemical properties of the isolated compounds have been determined.
4. Kinetics of decomposition of benzenediketodicarboxylic and benzenemonoketodicarboxylic acids in nitrogen and oxygen current has been investigated and on the basis of comparison of these reactions rate constants the scheme of behavior of oxidation reaction of diethylbenzenes has been proposed.
5. 45 derivatives of 1,3- and 1,4-benzenediketodicarboxylic and 1,3- and 1.4-benzenemonoketodicarboxylic acids have been synthesized for the first lime and their structures have been elucidated using the modem physical and chemical methods of investigations (1R-, NMR, mass-spectroscopy and X-ray analysis)
6. Among the synthesized compounds were found substances possessing anti-inflammatory, antimicrobial and growth stimulant properties and the interrelations of these activities with their structures have been specified.
7. Preparation of Ketostim, an effective growth stimulant of cotton, allowing to increase productivity of a raw-cotton by 10-15% was synthesized on the basis of the mixture of benzeneketodicarboxylic acids. Economic effect from the usage of Ketostim preparation in cotton-growing makes 150-250 thousand sums per hectare.
8. The technology for the production of Ketostim preparation has been developed and created an experimental-industrial installation in the experimental plant of UzCPRl and all the necessary reference documents have been made. Ketostim preparation has passed the State tests and by the Decision of the Presidium of the State Chemistry Committee of RUz it has been included into the list of licensed preparations for use as a biostimulant in presowing treatment of cotton seeds.
9. Optimum conditions for carrying out of the process of etherification of
2.4- dichlorobenzoic acid with 2-butynediol-l,4 depending on a ratio of the catalyst, solvent and duration of reaction have been found. It has been shown that
2.4- dichlorobenzoyloxybutyne-2-ol-4 has also been formed alongside with 1,4-bis-(2,4-dichlorobenzoyloxy)-butyne-2. The methods of isolation of l,4-bis-(2,4-dichlorobenzoyloxy)-butyne-2 from the mixture of ethers have been developed. The process of 1,3-dipolar cyclocombination of phenylazide with l,4-bis-(2,4-dichlorobenzoyloxy)-butyne-2 has been investigated and the optimum conditions of reaction behavior with the formation of l-phenyl-4,5-bis-(2,4-dichlorobenzoyloxymethyl)-l,2,3-triazol (dichlotazol), with an output of 85.5 % have been found and on the basis of the carried out investigations the experimental-industrial technological regulations have been compiled.
10. Drug forms of an anti-inflammatory dichlotazol preparation in the form of 3% ointment and tablets in 0.025 g have been developed and the experimental-industrial technological regulation and TPA for the production of ointment have been made. On the basis of the carried out clinical investigations the dichlotazol preparation in the form of 3% ointment was permitted by the Quality Control Bureau of Medicinal Drugs and Medical Techniques (QCBMD and MT) of the MH RUz for medical application as an anti-inflammatory drug for use in the gynecologic practice.

The chemical composition of the PbO-SiO₂ based glass resin was analyzed using physico-chemical and differential thermal analysis methods. Experimental work on researching physico-chemical properties and determining the possibilities of obtaining transparent glass based on them was carried out using traditional methods of physico-chemical and glass technology. It has been experimentally proven that 70%PbO+30%SiO₂ and 80%PbO+20%SiO₂ are the optimal compositions for obtaining transparent glasses based on the PbO-SiO₂ system. Based on the obtained glass mixture of such optimal composition, it is possible to obtain transparent glass that can be fired at low temperatures, and it has been found that the glass with a PbO content of 70-80% has a high refractive index.

The aim of the research work is to improve the synthesis of certain biologically active derivatives of ferrocenecarboxylic acid and classify them on the basis of the chemical composition of the preparation of acetylferrocene and ferrocenic acid.
The scientific novelty of the research work is as follows:
the method of obtaining acetylferrocene;
a new method for the production of ferrocenecarboxylic acid;
the formation of l'-(p-hydroxyphenyl) ferrocenecarboxylic acid in the diazotization reaction of ferrocenecarboxylic acid was first established;
new biologically active compounds based on ferrocenecarboxylic acid and water-soluble aromatic acids of ferrocene have been synthesized and a positive effect on the germination and energy of germination of cotton seeds has been established.

The aim of research work is synthesis of nitrogen-, phosphorus-, oxygencontaining complex-forming polyfunctional polymer ligands, obtaining of complex compounds of some d-metals on their basis by sorption method and study the composition, structure and properties of the obtained compounds.
The scientific novelty is as follows:
for the first time synthesized new nitrogen-, oxygen-, phosphorus-containing complexing polyfunctional polymeric ligands - poly-2-oxo-l,3-di (hydrazinomethyl) -5-N-hydroxymethylaminocarbonyl-l,3,5-triazine (L1); poly-2-oxo-l,3-di (phosphonoxymethyl) -5-N-methylaminocarbonyl-l,3,5-triazine (L2); poly-di (3-aza-5,6-dioxohexyl) -dithiophosphate potassium (L3) and poly-di (3-azabutyl) -dithiophosphate potassium (L4);
the electronic structures of molecules of polydentate polymer ligands were calculated by semiempirical quantum-chemical methods AM-1, MNDO and PM3, their geometric parameters and energy characteristics were determined, and the most probable centers for localization of the coordination bond were identified based on charge control.
static exchange capacities of synthesized polymer ligands for Си (II), Zn (II), Cd (II) and Ag (I) ions were determined and a number of sorptivity of these metals with the resulting ligands was constructed;
16 new coordinated compounds Си (II), Zn (II), Cd (II), Ag (I) were first obtained chelate type with synthesized polymeric ligands; their composition and structure were determined using modern physicochemical methods of analysis;
determined constant stability and revealed the series of thermal stability of the obtained complex compounds, it is proved that the stability of complexes grows in the series L1—>L2—>L4->L3 and Zn (II)—>Cd (II)—>Cu (II)—>Ag (I) in accordance with the Pearson’s principle of «Hard and soft acids and bases».

The aim of research work to develop methods for the synthesis of new mono- and bis- molecular tetrahydroisoquinolines, as well as to determine the physicochemical properties.
The objects of the research work are homoveratrilamine, organic acids, selected substituted tetrahydroisoquinolines and their new derivatives, obtained using the developed methods.
The scientific novelty of the study is as follows:
new method has been developed for obtaining mono- and bis-derivatives of substituted 1,2,3,4-tetrahydroisoquinolines based on homoveratrilamine and a number of acids, including the targeted synthesis of new biologically active compounds:
the synthesis of 32 new derivatives based on the interaction of homoveratrilamine with a number of mono-basic acids (С7 0-С22Л, Cisi Л9 cis and trans fatty acids, 3-indolylacetic, glycolic acid, and o-, m-, p- pyridinic acids) had been done for the first time;
it was found the reaction with glycolic acid proceeds with the formation of an unusual tricyclic product, aziridine-borane;
it has been proved that the Mannich and Craig reactions of 6,7-dimethoxy-l-(lH-indol-3-yl) -1,2,3,4-tetrahydroisoquinoline with formalin yield one five-cyclic derivative;
the synthesis of the bis- isoquinoline derivative based on natural and anthropic acid was first carried out and new methods for the synthesis of the alkaloid co-rydaldin were found;
Implementation of the research results: On the basis of scientific results obtained on the synthesis of isoquinoline alkaloids and their analogues based on certain carboxylic acids:
the crystalline structure of the synthesized 2,3-dimethoxy-5,6,7,8,13,13a-hexahydro-6a,8-diazoindeno[2,l-b]phenanthrene and introduced into the International Cambridge Center for Structural Data (Cambridge Crystallographic Data Center reference No. 1412105 of January 11, 2017). Scientific results allow synthesizing new substances that are part isoquinoline classes;
crystalline structures of N, N' - (3,4-dimethoxy-P-phenylethyl) diamide oxalic acid and 6,7-dimethoxy-l,3,4,8b-tetrahydroazirin[2,la]isoquinoline-N-borane, on the basis of the condensation and cyclization reaction of glycolic acid and homoveratrilamine, are introduced into the Cambridge Crystallographic Data Center international reference No. 1014600 and 1014601 of 11 January 2017. Scientific results allow to synthesize purposefully new substances with different properties;
a methodology for the synthesis of isoquinoline alkaloids and their analogues in the JSC Kokand superphosphate plant (reference 03-231 of February 22, 2017). The developed method allows the synthesis of new compounds based on mono-and bis-molecular tetrahydroisoquinoline.
The structure and volume of the thesis. The structure of the dissertation consists of an introduction, three chapters, conclusion, a list of references and an appendix. The volume of the dissertation is 110 pages of computer text.

Inquiry of the Subject: Precursors Nominal Structures Bi, 7Pbo3Sr2Can.iCunOy (n = 2-5) on the Basis of the System Bi2O3-PbO-SrO-CaO-CuO. Superconducting Ceramics on the Base of the System Bi2O3-PbO-SrO-CaO-CuO.
Aim of the Inquiry: the purpose of the given work was research of the mechanism of formation and properties of high-temperature superconducting materials and ceramics on the basis of the system Bi2O3-PbO-SrO-CaO-CuO, synthesized under the influence of a sunlight. Interrelation revealing between reception conditions precursors, the mechanism of formation of superconducting phases, and critical properties of the high-temperature superconducting ceramics.
Method of Inquiry: the rentgenophases analysis, the electron-microscopic analysis, DTA, a method of hydrostatic weighing, micro hardness, temperature dependences of a magnetic susceptibility, the magnetic moment and electro resistance.
The Achieved Results and Their Novelty: for the first time it was synthesised with utilize of the concentrated solar energy superconducting connection gomologics of some Bii 7Pbo 3Sr2Can.iCunOy(n = 2-5) and were investigated their mechanism of formation. And it is established that Increase of speed of interphase reactions turned out to be connected with a metastable initial condition. It is introduced corrective amendments in a structure of the private system Bi2O3-PbO-SrO-CaO-CuO, connected with incongruent character of formation of the phases 2234 and 2245. For the first time they were revealed steady (more than 7 years) new superconducting phases from the Hardware in an interval 110-150 K. It is established that the reason of their formation turned out to be formation of periodic defects in CuO2-planes in a direction [110].
Practical Value: can be used for synthesis of superconducting phases with the set temperatures of superconducting transition in an interval 95-150 К at Bij jPbojS^Can. iCunOy (n = 2-5). The developed method of reception of superconducting ceramics on the base of connections Bii ^Pbo sSbCan-iCunOy (n = 2-5) with Tc= 110-150 К can be the basis for creation of new technologies of reception of materials with special electric properties. The developed method is the contribution to development of power saving up technologies.
Degree of Application and Economical Efficiency: the gotten results are plugged in a database on inorganic connections “The American Mineralogist crystal structure database”.
Sphere of Usage: electronics, power.

The aim of research work is to synthesize new compounds based on ferrocene and methylolurea, to identify their biostimulating activity for plants, to develop commodity codes for newly synthesized biostimulators based on chemical composition and to introduce them into practice.
The object of research work was ferrocene, monomethylolurea, dimethylolthiourea and their derivatives.
The scientific novelty of research work is as follows:
new biologically active compounds based on ferrocene and methylolurea as well as their derivatives were synthesized for the first time; the formation of the derivatives of p-ferrocenylphenol, m-ferrocenylbenzoic acid with methylolurea and methylene dicarene as a result of the diazotization reaction in various solvents has been proved;
chemical compositions and physical properties of biologically active substances containing derivatives of ferrocene and methylolurea are determined; The biological activity of synthesized compounds, their influence on the germination of cotton seeds, the growth and development of cotton and its yield have been proved.
Introduction of research results. Based on the scientific results of the study of synthesized biologically active compounds based on ferrocene and methylolurea:
in 2012-2016 years. In Andijan and Fergana provinces, the technology of using the ADUMAKH biostimulator synthesized on the basis of ferrocene and methylolurea has been introduced on a total area of 100 hectares (certificate of the Ministry of Agriculture and Water Resources of the Republic of Uzbekistan dated December 27, 2017 №07 / 23-1126). At the same time, from every hectare of the area treated with the biostimulator, an additional 3-5 centners of yield was obtained. According to the commodity nomenclature of foreign economic activity, a commodity code has been developed for ferrocene and its derivatives 2942 00 000 1, for nitrogencontaining ferrocene derivatives 2942 00 000 2 and introduced into the practice of the state customs service (certificate of the State Customs Committee of the Republic of Uzbekistan dated Yanuar 06, 2018 №1/16-8). As a result, it became possible to classify biologically active compounds containing ferrocene and nitrogen.

The actuality and claiming of the theme of dissertation. Currently, the global diversification of oil and gas industry, including the introduction of innovative technologies in the petrochemical or heavy organic synthesis in modem conditions is 62-67%. Chemical processing of oil and gas as well as obtaining on the basis of thin organic synthesis products and materials for agriculture, chemical, pharmaceutical, textile, energy, automotive and aircraft industries is highly effective.
In the years of independence the Republic pays great attention to the development of scientific research in the field of chemical industry new products and sales, and achieved certain results of a wide range of measures to meet domestic import-substituting chemicals needs.
To date, the introduction of the world chemical industry in modem technology synthesis of new types of organic compounds, based on their creation of polymeric and plastic materials with unusual properties, solvents, fungicides, stimulants, antibiotics, hormones, adhesives and paints is perspective task. Synthesis based on Tabor reactions, Grignard-Iotsicha and diazotization new aromatic acetylene alcohols, and vinyl esters, the development of highly effective mechanisms for increasing the yield of the product, the creation of eco-friendly, non-waste resource-saving technologies, the structure of the establishment and properties of aromatic acetylene alcohols, and vinyl esters of modem physicochemical methods to obtain their chemical-based corrosion inhibitors, biocides against biological corrosion processes, ion exchangers for scaling and defoliyantov for use in agriculture is promising.
This dissertation investigation in some degree is devoted to fulfillment of tasks mcnshioncd in decision of President of Republic of Uzbekistan PD-916 from July 15, 2008 «Additional measures of stimulation of using innovational projects and technology in production», PD-1442 from December, 15, 2010 «Perspectives of development of production on 2011-2015 years in Republic Uzbekistan» and also some others normative-legal acts.
The aim of research work is opening of physical out physical characteristics of synthesis of new aromatic acetylenic alcohols and their vinyl ester on the base local raw material and waste, and also elaboration of new industrial technologies.
Scientific novelty of the research work is as follows:
in the catalyst systems of KOH+TGP and NH3+KOH+CH3OH and on the basis of organic compounds of magnesium, and reacting the diazotization synthesized aromatic acetylenic alcohols systematic analysis of the effect of various factors on the yield of the products; on the basis of the results obtained, the synthesis technique developed by aromatic acetylenic alcohols;
scientific bases the effect of the structure of the ketone molecules, direct and able ramified radicals with >C=O group in the synthesis process;
for the first time in the selected super basic system (MOH-CsF-DMSO) and of heterogeneous catalytic component (MOH/Caktiv) aromatic acetylenic alcohols vinylation with acetylene, as well as some of the etherification of unsaturated carboxylic acids synthesized new renewable energy;
first proved synthesized aromatic acetylenic alcohols exhibits inhibitory activity against biological corrosion of steel and metal structures of the oil and gas industry and proved their high activity as biocides;
it is shown that the use of the armed forces of aromatic acetylenic alcohols can get drugs that produce sulfur compounds from natural gas and crude oil primary processing.
CONCLUSION
On the basis of the researches on a doctoral theme «Synthesis of aromatic acetylenic alcohols and their vinyl ethers» provided the following conclusions:
1. Applied catalytic system KOH+TGP and NH3+KOH+CH3OH obtained on the basis of local raw materials and industrial waste serve to improve aromatic acetylene alcohol production technology.
2. Systematization process for producing aromatic acetylene alcohol based phcnylacctylene, aniline and organomagnesium compounds is essential.
3. Expediency effective catalyst compositions with nanostructures based impregnating alkali activated carbon of different sizes during vinylation of aromatic acetylene alcohols homogeneous and heterogeneous catalytic methods.
4. Synthesis of new derivatives etherification various acetylenic alcohols and aromatic vinyl ethers hydro sulfuration will serve to expand the industry synthesis of organic compounds.
5. It has been shown that the development of technology for producing aromatic acetylenic alcohols and vinyl esters using local raw materials, waste or by-products, catalysts and process equipment will be improved and the development of the technology of organic chemistry or organic substances.
6. Applications aromatic acetylene alcohols as corrosion protection of biocides in the biological corrosion of steel and metal industry equipment Oil and gas leads to a 80-82% disinfection of bacteria and fungi and improve the performance properties of metal equipment.
7. The use of vinyl esters of aromatic acetylenic alcohols for complex allocation of sulfur compounds from the oil, petroleum products and natural gas reduces the amount of sulfur compounds to 42-55%.
8. The use of phosphate esters of aromatic acetylenic alcohols as scale inhibitor industrial wastewater, and vinyl esters of thiodiglycols as cross linking agents in the production of rubber and rubber products leads to economic development of the chemical industry.

Subjects of the inquiry: hexamethelendiisocyanate.
Aim of the inquiry: synthesis and technologies of reception an biscarbamates on the basis of spirits, an establishment of their structure, studying of their chemical properties and growth factor activity, highly active substances to recommend to practical application in an agriculture.
Methods of inquiry: organic and technological synthesis, the hromatografic analysis, the element analysis; IK-and PMR-spectroscopy, the classical chemical analysis.
The results achieved and their novelty: Technologies of reception of new derivatives an hexamethelen bis [(alkyl)-carbamate] are synthesized and developed and their structures are established. For the first time derivatives an bis-carbamates are synthesized: N,N'-dinitrozo, N,N'-dinatrii-, N,N'-dimethel- and N,N'-dihlorreplaced, their structures are established. Connections and their replacements are created new carbamates of N-H groups, in studying which chemical properties the opportunity to develop a new direction on studying chemistry of connections opens.
Practical value: On the basis of the primary, secondary and tertiary spirits, being by interesting object the general method of organic synthesis and without waste technology is developed for studying derivatives an bis-carbamates in educational process for practical works of students; as a fundamental problem of technology of organic synthesis; by search new highly effective growth factors, and also less toxical medical products.
Degree of embed and economig effectivity: Drug XM-1 XM-2 is tested in three of the Kashkadarinskai range on a cotton plant, corn and a sunflower. Thus economic efficiency on calculation of experts compounds 4,4 mlrd som.
Sphere of usage: reagent, growth factor of plants.

Subjects of the inquiry: watersoluble and waterswelling polymers on the base of glycolic acid.
Aim of the inquiry: construction of new pH-scnsiblc watcrsolublc and waterswelling polymers on the base of glycolic acid, investigation of particulates their formation, physico-chemical properties and also finding of some perspective spheres of their using.
Methods of inquiry: chemical, physico-chemical and physical.
The results achieved and their novelty: for the first time new acrylic monomers on the base of glycolic acid were synthesised with the aim of obtain of pH-sensitive polymers. Some particulates of radical polymerization of these monomers in water solution were investigated. Hydrogels on the base glycolic acid, sewing dy different crossing agents were obtained and their degree of swelling in conditions of their synthesis was investigated and also the base parameters of active chain of obtained crossing polymers were determined. The obtained hydrogels have been pH-sesitive polymers. It was shown by investigation of realeasing of tubazid and apressin immobilized by hydrogels in water solutions the prolongation action of these medicines on the polymer matrix.
Scientific and practical value: obtained new watersoluble, waterswelling and pH-sensitive polymers can be used at construction of pH-sensitive systems able to transport purposefully biology active compounds and their modificators. The obtained results will be enlarge a knowledge in field of radical polymerization of ionogenic monomers and also can be used for further developing of theoretical ideas about of synthesis of polymers by crossing structure.
Degree of embed and economic effectivity: the obtained results of investigations of radical polymerizations of some ionogenic monomers on the base of glycolic acid, synthesis of pH-sensitive polymers of liner and cross-linking structure were introduced in education process of the National University of Uzbekistan after name Mirzo Ulugbek and also used at lectures for magisters by speciality 5A440407 - Chemistry of high molecular compounds.
Sphere of usage: medicine.

Actuality and demand of dissertation theme. Every year 10% of metals are destructed in result of corrosion rising owing chemical and electrochemical interactions with environment what has caned to financial waste amounting by millions of sums1. The material for mordent technologies - alloys on the base of iron in great degree undergo to corrosion under action of air’s oxygen, moisture and exide’s of sulfur, nitrogen and other chemically- active compounds.
During years of Independence in Republic the great attention has been devoted to development of scientifically investigation in field of chemical industry production of new type of productions and their realization and at this some results by satisfaction of local market in import substituted chemical products. From this paint of view for protection of metal equipment working in water systems, in nets of water-supplying, oil-pressuring and oil chemical industries and also energetically installations problem is arised by using of new inhibitors obtained in the base of organic and oligomeric compounds and grate degree prolonging time of its explutations.
Carrying out of purpose investigation by increasing of quality of metals and their effective using is important un all world at this special attention is devoted to following tasks: using of water-soluble oligomeric and polymeric inhibitors fighting with salt-deposits, determination of optimal conditions as of inhibition of metals corrosion, synthesis of water-soluble inhibitors on the base of nitrogen and phosphorous- containing compounds effectively protecting black and non-ferrous metals from corrosion in deferent mediums, investigation of mechanisms of their action, determination of different physic-chemical particulates. Investigation by protection properties abovementioned inhibitors in results of their adsorption interaction with surface of metallic equipment at different temperatures and studying of mechanisms of their action are at presence time are actual tasks.
This dissertation work is oriented on realization of decision of president of Republic Uzbekistan PP-1442 from 15 december 2010 year year «About priorities of development of industry of Republic Uzbekistan in 2011-2015 years» and also decisions of Cabinet Ministers of Republic Uzbekistan from 09.12.1992 year «About protection of environment of Republic Uzbekistan», from 27.05.2013 year «About program of additions by protections of environment of Republic Uzbekistan on 2013-2017 years».
Aim of investigation. Construction inhibitors of oligomerical type which are a new class of compounds of effective inhibitoral protection metals from corrosion investigation and physic-chemical regulatory of different mediums by watersoluble oligomer inhibitors.
Scientific novelty of dissertational research is concluded in following:
for the first time nitrogen, phosphorous and sulfur containing adducts of thiourea, urea melamine and oligomerical type on the base of phosphorus acid have been synthesized;
mechanisms interactions and protections of metals by oligomer inhibitors;
determination of optimal conditions of influence of concentration, temperature on corrosion current velocity of corrosion, degree of protection, coefficient of breaking, and also using of inhibitors for high effective protection;
degree of filling of electrodes and constants of adsorption equilibrium of metals corrosion by different nitrogen containing, organic compounds and also by adducts on the base phosphorous acid and oligomer inhibitors have been determined by electrochemical and gravimetrical methods;
it was shown that synthesized oligomers have formed protective lowers on the steel surface which in great degree have distinguished by composition and structure from initial samples in different mediums.
CONCLUSIONS
The following conclusions on doctoral dissertation «Synthesis and physicchemical properties of oligomeric inhibitors of corrosion on the base of N, P, S containing compounds» are represented:
1. Number of nitrogen and phosphorous -containing adducts on the base of phosphates of thiourea, urea, melamine andhexamethylendiamine and also inhibitors of oligomeric type on thebase of nitrogen containing organic compounds and phosphoric acid have been synthesized. Molecular dynamical and quantum chemical characteristics of synthesized compounds were determined, mechanism of inhibition by oligomeric compounds was established and general regularities inheriting to such inhibitors were determined what mill promoted to elaboration of new approaches of purposeful synthesis of inhibitors.
2. It was shown that such oligomeric compounds as phosphate of dimethilourea (OIK.M-8) have displayed effect of inner molecular synergism owing to presence of different functional groups and mechanism of their adsorption is differed by fact of formation of more compact layers of inhibitors on the surf are of metal and correspondely increasing their inhibition effect.
3. By using kinetics and thermodynamically investigation it was shown that adsorption properties of inhibitors of oligomeric and low-molecular type have different about what high values of filling degree of electrode surface and constants of adsorption equilibrium are witnessed. Constant of equilibrium in 4 time is higher it’s value of low-molecular inhibitors.
4. Systematical studying of two component inhibitors on the base of dihydrophosphate of potassium was carried out and it was found that addition of second component has increased their inhibitional action, from obtained results conclusion have been mode about passible mechanism of their protective action which has included formation of thin layers of complex composition preventing appearance of ulcerous corrosion.
5. Effectively of inhibitor dimetilolmelamin in aggressive mediums with increasing temperature has increased before achieving definite temperature after which it didn’t changed what has indicated on chemo-sorption mechanisms of action of this inhibitor forming strong protective layers on the surface of protective metal.
6. Phosphates dimethilolurea and dimethilolmelamine in mediums with different values of pH have formed on the steal surface protective layers which differed by composition and structure from initial samples, it was determined that their compounds were acted as anionical inhibitors with braking of anodic process.
7. Oligomeric inhibitors of OIKM-8 and OIK.M-9 and composition on their base have demonstratedthe highest effectively and they were tested Becabod metallurgical combination, AJ «Navoiyazot», ООО «Elektr uskuna sozlash» and «Suvoqova» of PKP and also UDP «Fergana» NPZ.

The aim of the research work are physico-chemical study of the synthesis of new effective defiliruya compositions and technologies for identifying optimal technological parameters of production complexometric defoliants of cotton on the basis of tricarbamide sodium, magnesium chlorate, nitric acid extraction of DCCP and monoethanolamine salts of citric, nitric, acetic acids and ethylene products.
The object of the research work chlorates of sodium and magnesium, carbamide, ammonium nitrate, acetic, nitric, citric acid, demoniacally citrate, ammonium citrate, acetate of monoethanolamine, monoethanolamine nitrate, DCCP physiologically active substance CNitAEDCCP and ethanol.
Scientific novelty of the research work: established physico-chemical basis for interaction of the components in the systems involving water, chlorate of sodium, magnesium, urea, citrate of demoniacally, ammonium citrate, monoethanolamine nitrate, acetate monoethanolamine and teleproduction built their polythermal solubility diagram and diagrams «composition-properties»;
proven education selected four new compounds, with distinction concentration and temperature limits of existence of the equilibrium solid phases in the diagrams, the individuality of which is identified chemical and physicochemical analysis methods;
proven optimal technological parameters of the extraction process waste cotton processing plant nitric acid, which proved that, when the nitric acid concentration is 20%, the ratio of waste to acid is 1:10, the process temperature 50°C, the transition of citric acid to the solution of 4.25%;
the technology of production of complexometric defoliants on the basis of chlorate of magnesium, sodium tricarbonate and physiologically active substances;
analyzed the composition of the defoliant «UzDEF» chemical and physicochemical methods, according to which the defoliant «UzDEF» has the following composition: 32,0% Mg(ClO3)2, 10% CO(NH2)2, 1,5% NH4NO3 и 0,3%АМЭА.
Implementation of the research results Defoliants “UzDEF and UzDEF-K” was included by the state chemical Commission of the Republic of Uzbekistan to the list of drugs permitted for use in agriculture (Certificate No. 1 And 082 of January 18, 2008 and Certificate No. 1 And 1168 dated 18 October 2016); methodological recommendations on the protection of the environment and human health when used in agriculture defoliants «UzDEF», «UzDEF-K» and approved by the Ministry of health of the Republic of Uzbekistan.
Practical implementation of technology for new defoliant “UzDEF” implemented in joint-stock company “Ferganaazof ’ and developed from 2009 to 2016 more than 10.4 thousand tons of defoliant (The reference of «Uzkimyosanoat» from August 15, 2017 №01/3-4335/П).
Agrochemical testing of the proposed defoliants on cotton has shown a high defiliruya activity and the “softness” of their action on plants compared to liquid magnesium chlorate defoliant. The degree of leaf fall was more than 89,7 %. Defoliants stimulated the opening of boxes, the figure on the 12th day of 89,6-92,3%. The increase in productivity up to an average of 1,8-2,2 t/ha. Definition of economic efficiency of production of new defoliants “ “UzDEF and UzDEF-K” showed that the cost of 1 ton of defoliants “UzDEF and UzDEF-K.” for raw materials is respectively 5479275,6 and 5562311,82 sum, this figure compared with the 1 ton IChMD 617324,4 and 534288,18 sum cheaper.
The structure and volume of the thesis. The structure of the thesis consists of introduction, five chapters, conclusion, bibliography and applications. Scope of the thesis is 181 pages.

The aim of the research work is synthesis of pyrido[2,3-d]pyrimidin-4-ones and the comparative analysis reactionary in reactions with electrophilic reagents.
The aim of the research work is synthesis of pyrido[2,3-d]pyrimidin-4-ones and the comparative analysis reactionary in reactions with electrophilic reagents.

The urgency and relevance of the theme of dissertation. In the world it is actual the application of modifiers on the basis of synthetic oligomers for improving the rheological properties and the regulation of structure formation of composite materials.
In the Republic of Uzbekistan, one of the most important problems in the field of chemical additives for building materials is to find new organic additive that increases endurance and durability of constructions and structures, subjected to impact of climatic conditions and aggressive environments.
In construction industry for regulating processes of structure formation and rheological features of concentrated suspensions arc used supcrplasticizers - organic chemical additives, allowing purposefully to change the mobility of raw mixtures and properties of ready made materials. The search of new effective additives that allow to modify the surface of interface phase and modify rheological properties of dispersions is an actual task.
The special properties of polyelectrolytc-supcrplasticizers refer the possibility of stabilizing dispersions and emulsions by adsorbing diphyletic macromolecules at the bound of interface, preventing the aggregation of particles; effect on the rheology of fluids and dispersions; ability to form physical gels; possibility to cause aggregation of particles in stable dispersion systems to facilitate the separation of liquid and solid phases; modification of surface properties on adsorption on them for providing wettability; solubilization of hydrophobic substances, by adsorption of supcrplasticizer on the surface of the solid phase particles precludes their adhesion by electrostatic forces and thereby reduces the viscosity of the suspension.
The dissertation to some extent may contribute to solve problems defined in accordance with the part of provisions by the President of the Republic of Uzbekistan № 1442 dated December 15, 2010 «About priorities of industrial development the Republic of Uzbekistan» and № 1072 dated March 12, 2009 «About program measures on realization of the most important projects on modernization, technical and technological reequipment of production», as well as other legal documents adopted in this area.
The aim of the research is the working out technology on obtaining organic super- and hypcrplasticizers based on local raw materials and the improvement of their means the technology production of cement compositions.
The scientific novelty of the research concludes the followings:
the technology of the new super- and hypcrplasticizers based on polycarboxylates and acetonoformaldchydes resin was worked out;
the structure and physic-chemical properties of synthesized organic chemical plasticizing additives based on polycarboxylates, polyols, acetonoformaldchydc resin was defined;
the influence of obtained plasticizing additives on the basis of polycarboxylates, polyols, cellulose derivatives and starch, acctonoformadchydc resin on physical-mechanical properties of cement systems was defined;
the physico-chemical properties of cement systems with the addition of su-plasticizer SDj-1 and hypcrplasticizer and supcrplasticizer on the base of accton-oformaldchydc resin was defined.
technology of application of obtained super- and hypcrplasticizcr of cement composition was worked out.
CONCLUSIONS
1. Obtained plasticizers based polyols and revealed that an increase in molecular weight polyol had a positive effect on the rheological and physico-mcchanical properties of the cement paste. It was determined that the plasticizer based on glycerol compared with other plasticizing additives which was obtained , showed the best results.
2. Obtained plasticizers which were synthesized from renewable sources (like starch, cellulose and derivatives thereof), had a positive effect. It was identified derived plasticizers were encouraged to use in the range of 0.1 - 0.5% by weight of cement.
3. Obtained supcrplasticizer SDj-1 in its chemical structure had functional groups that enhance the water solubility and adsorption on the particles of a macromolecule supcrplasticizer was proposed Portland cement and in the workplaces.
4. It was found that the isobutyl radical was effective for a polymcthylcnc radical modification, the optimum percentage of supcrplasticizer SDj-1. isobutyl and the radical - 95: 5, and the proposed modified supcrplasticizer was added to the cement paste - up to 1% by weight of cement.
5. It show that the resulting of hypcrplasticizcr had a high plasticizing effect when added mixes and can repeat the results with small quantities of superplasticizers. Hypcrplasticizers were 20 times more effective than supcrplasticizers.
6. It was proposed that supcrplasticizer of acctonoformaldchydc based resin having functional groups in its chemical structure, which improved the water solubility and adsorption on the particles of a macromolecule supcrplasticizer and Portland cement showed the results obtained by supcrplasticizer reduced the necessity to 15-20%, increased the strength of the cement stone.
7. It was determined that in addition to synthesized and super hypcrplasticizers of composites solutions based on gypsum and ccmcnt-limc binding was increased the mobility, placcbility, density and strength.
8. The technology of production and application of super- and hyperplasticisers based on local raw materials and implemented on the basis of LLC «Zcnatkor-TBB», LLC "Qulama qurilish", LLC "Jizzakh Binokor Savdo". By adding the received hyper and super plasticizers in cementitious systemsobserved to increase strength cement compositions in the early stages, and this in turn led to a reduction of the technological process of preparation of composite materials and energy costs

Subject of research: moleskin and efire alleged factions, ethyl and izoamile alcohols, cretonne alleged, foamy, copper-molybdic ore, spume.
Purpose of work: reception, study characteristic and using import substituting spume for flotation enrichments copper-molybdic ore.
Methods of research: physic-chemical and chemical tests, IR-spectroscopic, PMR- study, paper chromatography, mathematical and steady-state analysis.
The results obtained and their novelty: on base individual material, as well as secondary raw materials resource local chemical production is received row superficially an active material (PVA), explored their characteristic (spume, superficially-active, efficiency spume action under flotation enrichment copper-molybdic ore and others), characteristic solution, as well as possibility of the efficient practical application as spume under flotation an enrichment sulfide ore.
Practical value: synthesized PAV recommended for practical application under flotation enrichment copper-molybdic ore as efficient import substituting foamy reagent.
Degree of embed and economic affectivity: efficiency of the using synthesized PAV as foamy under flotation enrichment copper-molybdic ore practiced in condition JSC "Almalyk is blazed-metallurgical combine", are received positive results. Expected annual economic effect from introducing the development will form on reagent TMSB 900 mln.sum/year, and on EAFK 740 mln.sum/year, it will provide import substituting and spare exchange facilities of the Republic.
Field of application: is blazed-metallurgical industry.