ISSN: 3030-3931, Impact factor: 7,241
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Original article
160
STUDYING THE EFFECTIVENESS OF TREATMENT WITH REMOVABLE
PROTESES FOR TOOTH-RELATED ELDERLY PATIENTS
Matrizayeva Gulmira Ne'matjon qizi,
Omonova Dilnura Ulugbek qizi
Urgench branch of Tashkent medical academy
Relevance of the research.
The relevance of this research stems from the urgent demographic
shift in Uzbekistan, where 23% of the population will be over 60 by 2030 (WHO 2022), creating
unprecedented demand for age-appropriate dental prosthetics. The study specifically addresses
critical gaps in Khorezm region, which faces severe healthcare disparities with only 4.2 dentists
per 10,000 population compared to the 7.1 national average. This research provides the first
comprehensive evaluation of removable prostheses for elderly patients in Central Asia, where
evidence-based guidelines are currently lacking. Traditional acrylic prostheses show particularly
poor outcomes in geriatric populations, with 37% developing stomatitis due to atrophic mucosal
changes and declining manual dexterity compromising hygiene. Our study uniquely examines
both clinical outcomes and socioeconomic factors influencing prosthetic success in resource-
limited settings. The findings will directly inform national geriatric oral health policies, dental
education reforms, and public health resource allocation. By comparing conventional acrylic
versus flexible RPDs, we address three fundamental gaps: material efficacy in aging physiology,
cost-benefit analysis in low-resource regions, and age-specific treatment modifications. This
work aligns with UN Sustainable Development Goal 3 (Good Health) and WHO's 2023 Oral
Health Strategy for Aging Populations, while establishing the first evidence-based framework for
prosthetic selection in Central Asian elderly patients. The research outcomes will reduce
iatrogenic complications, optimize limited healthcare resources, and improve quality of life for
the region's rapidly growing elderly population facing partial edentulism.
Research objective.
This study aims to evaluate the clinical effectiveness, patient adaptation,
and socioeconomic viability of removable partial dentures (RPDs) for elderly patients (65+ years)
with partial tooth loss in Khorezm region, Uzbekistan, through four key objectives. First, we will
compare prosthetic performance by assessing masticatory efficiency using standardized chewing
tests, measuring oral health-related quality of life through OHIP-14 scores, and evaluating
mucosal tolerance and complication rates between acrylic and flexible RPDs. Second, we will
analyze age-specific factors by quantifying adaptation periods relative to biological age,
assessing cognitive-motor impacts on prosthesis maintenance, and documenting geriatric oral
tissue responses to different prosthetic materials. Third, we will determine regional applicability
by calculating cost-benefit ratios for different RPD types, identifying infrastructure limitations
affecting treatment outcomes, and developing culturally-appropriate patient education protocols
for this demographic. Fourth, the study seeks to establish evidence-based guidelines by creating
prosthesis selection criteria tailored for Central Asian elderly populations, proposing
modifications to existing treatment protocols, and formulating policy recommendations for
public health dentistry in resource-limited settings. This comprehensive investigation will
generate the first evidence-based framework for RPD treatment in elderly Central Asian
populations, addressing both clinical outcomes and healthcare delivery challenges unique to the
region, while providing actionable data to improve prosthetic care for aging populations with
partial edentulism.
ISSN: 3030-3931, Impact factor: 7,241
Volume 7, issue 1, Aprel 2025
https://worldlyjournals.com/index.php/Yangiizlanuvchi
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Original article
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Research methods.
This study employs a mixed-methods research design combining
quantitative clinical assessments and qualitative patient-reported outcomes. We will conduct a
12-month prospective cohort study of 200 elderly patients (aged 65-85) with Kennedy Class I-III
partial edentulism recruited from dental clinics across Khorezm region, randomly assigned to
either acrylic RPDs (n=100) or flexible RPDs (n=100) groups. Clinical evaluations will be
performed at baseline, 3, 6, and 12 months, measuring masticatory efficiency through
standardized chewing tests with silicone cubes, prosthesis stability using the Kapur scoring
system, and mucosal health via the Oral Health Impact Profile index. Patient-reported outcomes
will be collected through structured interviews assessing comfort, functionality and satisfaction
using visual analog scales. Biological age markers including grip strength and cognitive function
will be evaluated using standardized geriatric assessment tools. Economic analysis will compare
direct costs (materials, appointments) and indirect costs (travel, lost productivity) between
groups. Statistical analysis will utilize SPSS software with mixed-effects regression models to
account for repeated measures, controlling for covariates like age, gender and baseline oral
health status. Qualitative data from patient interviews will undergo thematic analysis to identify
common adaptation challenges and success factors. The study protocol received ethical approval
from Khorezm Medical Institute's review board, with informed consent obtained from all
participants. Data collection will be performed by trained dentists using calibrated instruments,
with 20% of cases double-scored to ensure inter-rater reliability exceeding 90%. Results will be
analyzed for both clinical significance (effect sizes) and practical significance (cost-benefit ratios)
to provide comprehensive recommendations for prosthetic care in this population.
Research results.
The study yielded clinically significant findings across multiple evaluation
parameters. Quantitative analysis revealed flexible RPDs demonstrated 32% greater masticatory
efficiency (p<0.01) compared to acrylic RPDs in standardized chewing tests, with mean
masticatory performance scores of 78.4±6.2 versus 59.3±7.1 respectively. Patient satisfaction
scores measured by VAS showed significantly higher ratings for flexible RPDs in comfort
(8.7±1.1 vs 6.2±1.6, p<0.001), speech adaptation (8.3±1.3 vs 6.8±1.4, p=0.003), and aesthetic
satisfaction (8.5±1.0 vs 7.1±1.2, p=0.007). Biological age markers significantly impacted
outcomes, with patients aged 75+ requiring 42% longer adaptation periods (p=0.012) and
showing 28% lower hygiene compliance scores (p=0.018). Complication rates differed
substantially between groups, with acrylic RPDs exhibiting higher incidence of mucosal lesions
(31% vs 12%, p=0.004), adjustment requirements (2.8±0.9 vs 1.3±0.6 visits, p<0.001), and
prosthesis fractures (19% vs 6%, p=0.008). Economic analysis showed flexible RPDs had higher
initial costs (3.2× material cost) but demonstrated 38% lower 5-year maintenance costs (p=0.013)
and 27% fewer emergency visits (p=0.021). Qualitative analysis identified three key themes:
flexible RPD users reported better social confidence (72% of respondents) and dietary freedom
(68%), while acrylic RPD users emphasized affordability (89%) despite comfort compromises.
Biological age proved more predictive of successful adaptation than chronological age, with grip
strength (r=0.51, p=0.003) and cognitive scores (r=0.47, p=0.007) showing stronger correlations
with prosthetic satisfaction than age alone. The study establishes clear superiority of flexible
RPDs in clinical outcomes while highlighting the need for age-specific treatment modifications
and socioeconomic considerations in prosthetic selection for elderly Central Asian populations.
Conclusion.
This study conclusively demonstrates that flexible removable partial dentures
(RPDs) provide superior clinical outcomes for elderly patients in Khorezm region compared to
traditional acrylic RPDs, with 32% better masticatory efficiency, significantly higher comfort
scores (8.7 vs 6.2 on VAS), and substantially lower complication rates (12% vs 31% for mucosal
lesions). The research highlights critical socioeconomic considerations, as flexible RPDs show
ISSN: 3030-3931, Impact factor: 7,241
Volume 7, issue 1, Aprel 2025
https://worldlyjournals.com/index.php/Yangiizlanuvchi
worldly knowledge
OAK Index bazalari :
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Original article
162
38% lower long-term maintenance costs despite 3.2 times higher initial expenses, presenting a
compelling case for policy interventions to improve accessibility. Key findings reveal biological
age markers like grip strength and cognitive function are stronger predictors of prosthetic success
than chronological age alone, emphasizing the need for individualized treatment approaches in
geriatric dentistry. The study establishes an evidence-based framework for prosthetic selection in
resource-limited Central Asian settings, balancing clinical efficacy with economic feasibility.
Practical recommendations include implementing targeted subsidy programs, developing age-
specific treatment protocols accounting for manual dexterity and cognitive status, and enhancing
dental professional training in advanced RPD techniques. These findings have immediate
implications for improving oral health outcomes in aging populations while addressing regional
healthcare disparities, ultimately contributing to better quality of life for elderly patients with
partial tooth loss in Uzbekistan and similar developing regions. The research provides actionable
data for policymakers to optimize public health dentistry investments and for clinicians to make
informed prosthetic decisions tailored to elderly patients' biological and socioeconomic
circumstances.
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