COAGULOGRAM INDICATORS IN HIV-INFECTED CHILDREN

HIV infection can significantly change the functioning of various organs and systems, including the hemostasis (blood clotting) system. HIV-infected children have various disorders, such as an increased tendency to thrombosis or, conversely, bleeding, which can lead to complications. Evaluation of the coagulogram helps in the diagnosis of these disorders.

The purpose of the work is to study the blood coagulation parameters in children with HIV infection at different clinical stages.

Materials and methods. In the course of the work, 89 children aged 4 to 18 years suffering from HIV infection were examined. The average age of the patients was 9.8 ± 0.49 years. The patients were divided into 4 main groups depending on the clinical stage of the disease.

Among these coagulation parameters, a reliable decrease in the platelet aggregation index was noted with normal platelet count, PTI, thrombin time and plasma fibrinogen.

Conclusions. Disturbances in the coagulogram in children at different clinical stages of HIV infection are represented by a decrease in the aggregation capacity of platelets, which is detected already at the initial stages of the disease.