Volume 03 Issue 04-2023
50
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
04
P
AGES
:
50-54
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
ABSTRACT
The article presents observational data of patients with varicose veins and analyzes the course of pregnancy. The
patients were divided into three groups depending on the type of varicose veins, the control group consisted of
healthy pregnant women who developed varicose veins during this pregnancy. The work was carried out on the basis
of the Department of Obstetrics and Gynecology No. 1 of the Samarkand State Medical University. The study revealed
exacerbation of the phenomena of varicose veins in the second - third trimester of pregnancy, as well as complications
of pregnancy compared with the control group.
KEYWORDS
Varicose disease, varicose veins of the lower extremities, varicose changes in the genitals, pregnancy, complications.
INTRODUCTION
The etiological factors in the development of chronic
venous insufficiency during pregnancy are considered
to be weakness of the vascular wall, dysfunction of the
endothelium of the veins, damage to the venous
valves, compression of the inferior vena cava and iliac
veins by the growing uterus. An important point is also
an increase in the concentration of progesterone in the
dynamics of pregnancy and an increase in the
Research Article
VARICOSE DISEASE AND PRECNANCY
Submission Date:
April 08, 2023,
Accepted Date:
April 13, 2023,
Published Date:
April 18, 2023
Crossref doi:
https://doi.org/10.37547/ijmscr/Volume03Issue04-07
Khudoyarova Dildora Rakhimovna
Dcs, Associate Professor, Head Of The Department Of Obstetrics And Gynecology №1 Samarkand State Medical
University, Samarkand Uzbekistan
Yusupov Orzimurod Shomurodovich
Phd Candidate Of The Department Of Obstetrics And Gynecology №1 Samarkand State Medical University,
Samarkand Uzbekistan
Journal
Website:
https://theusajournals.
com/index.php/ijmscr
Copyright:
Original
content from this work
may be used under the
terms of the creative
commons
attributes
4.0 licence.
Volume 03 Issue 04-2023
51
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
04
P
AGES
:
50-54
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
coagulation potential of the blood in combination with
congenital anomalies of the hemostasis system [1, 2, 4,
13, 15].
As a result, pregnancy creates favorable conditions for
the formation of CVI, but the mechanism of its
development has not been fully elucidated [3, 9, 17,
20]. Risk factors include a burdened family history of
venous pathologies; female; increased intra-abdominal
pressure (occurs as a result of an increase in div
weight); pregnancy; various pathologies of the
gastrointestinal tract and their various manifestations
(for example, constipation); prolonged standing.
Possible complications include infection, leg ulcers,
blood stasis, and thrombosis [1, 5, 7, 11]. Symptoms,
discomfort in the lower extremities in the form of a
sensation of edema, a feeling of heaviness and fullness,
convulsive twitching of the muscles of the legs, the
presence of pain (typical already in the later stages of
the development of the disease) [8, 12, 16].
Purpose of the study: to study the course of pregnancy
in pregnant women with varicose veins of various
forms.
MATERIALS AND METHODS
The examination data and the results of observation of
30 pregnant women with varicose veins who were in
the obstetrics and gynecology departments of the first
clinic of the Samarkand State Medical University from
2020 to 2022 were analyzed. Patients made the
following methods of examination: complete blood
count; blood biochemistry; coagulogram; blood
coagulation time, ultrasound and dopplerometry of
the vessels of the lower limb and the condition of the
fetus.
Depending on the type of varicose veins, the pregnant
women were divided into 3 groups: the 1st group
included pregnant women with varicose veins with
manifestations on the legs, the 2nd group included
patients with manifestations of varicose veins on the
genitals, the 3rd group included pregnant women with
varicose veins manifesting both on the legs and on the
genitals. The control group consisted of 20 practically
healthy pregnant women who developed varicose
veins during this pregnancy.
RESULTS AND DISCUSSION
The majority of pregnant women with varicose veins
were between the ages of 22 and 35, and the mean age
was 25.7 2.1 years. Patients in the control group were
also comparable in age. When clarifying the nature of
the work, it was found that varicose veins occur more
often in women who are in a vertical orthostatic
position for a long time, while in women leading a
sedentary lifestyle, the incidence occurred in 30% of
cases. Our studies allow us to confirm the data that in
the vertical position of the div under conditions of
orthostatic venous pressure, a significant expansion of
Volume 03 Issue 04-2023
52
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
04
P
AGES
:
50-54
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
the lumen of the saphenous and deep veins occurs.
From the anamnesis it followed that varicose veins
were observed either in the mother, or in the father, or
in close relatives of both sexes. Thus, every third
patient with varicose veins has a hereditary
predisposition to this disease. In patients with varicose
veins, according to the anamnesis, miscarriage was
noted in 16.67% of cases, and 6.67% of women had 2
miscarriages in anamnesis, more than 3 miscarriages -
3.33%. The anamnesis of the examined women is
aggravated by various extragenital diseases. The most
common anemia was 80% (24) among all patients with
varicose veins, obesity among the first group was 30%,
in the second and third groups, obesity occurred in 20%
and 40% of women, respectively. There was no obesity
in the control group.
In women who suffered from varicose veins before
pregnancy, progression of the disease was observed
depending on the duration of pregnancy. This was
manifested by edema, cramps in the lower extremities
and paresthesia, an increase in the number and
diameter of varicose veins. From the anamnesis, it was
revealed that the course of the first trimester of
pregnancy in 80% of the main group proceeded
without complications. In the II trimester, pregnancy
proceeded without complications in patients with
varicose veins in 60% in the control group in 80%. The
third trimester of pregnancy was characterized by a
progressive course of varicose veins in each patient of
the main group; chronic placental insufficiency and
fetal distress were more often diagnosed.
CONCLUSIONS
Based on the data, we can confidently say that varicose
veins become more complicated during pregnancy and
lead to complications during pregnancy.
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International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
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ISSUE
04
P
AGES
:
50-54
SJIF
I
MPACT
FACTOR
(2021:
5.
694
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(2022:
5.
893
)
(2023:
6.
184
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OCLC
–
1121105677
Publisher:
Oscar Publishing Services
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