Volume 02 Issue 09-2022
32
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
02
I
SSUE
09
Pages:
32-37
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
OCLC
–
1121105677
METADATA
IF
–
5.654
Publisher:
Oscar Publishing Services
Servi
ABSTRACT
The characteristics of the methods of checking the condition of the mucosa of the cavity of nose after the combined
surgical procedure performed in the nasal cavity are presented. Modern advances in medicine in the last decade allow
expanding the scope of simultaneous operative procedures. Simultaneous (joint, at the same time) operations allow
to eliminate several pathological conditions in the nose and paranasal sinuses at the same time. A strong curvature of
the nasal septum is one of the most common local factors associated with the pathology of cavity around the nose.
Disruption of nasal breathing leads to changes in mucociliary clearance and creates conditions for inflammation in the
cavity around of nose.
KEYWORDS
Nasal cavity, FESS, nasal sinuses.
INTRODUCTION
In modern medicine, diseases of the nose and
paranasal sinuses occupy the main place among the
diseases of the ENT organs. With the implementation
of FESS surgical procedures, the number of operative
Research Article
MORPHOLOGICAL CHARACTERISTICS OF THE MUCOSA OF CAVITY OF
THE NOSE AFTER VARIOUS SURGICAL PROCEDURES
Submission Date:
September 10, 2022,
Accepted Date:
September 20, 2022,
Published Date:
September 30, 2022
Crossref doi:
https://doi.org/10.37547/ijmscr/Volume02Issue09-07
U.S.Khasanov,
Researcher, Tashkent Medical Academy, Uzbekistan
A.A. Rakhimov,
Researcher, Tashkent Medical Academy, Uzbekistan
Journal
Website:
https://theusajournals.
com/index.php/ijmscr
Copyright:
Original
content from this work
may be used under the
terms of the creative
commons
attributes
4.0 licence.
Volume 02 Issue 09-2022
33
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
02
I
SSUE
09
Pages:
32-37
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
OCLC
–
1121105677
METADATA
IF
–
5.654
Publisher:
Oscar Publishing Services
Servi
procedures performed in the nasal cavity has increased
significantly. Currently, elimination of the pathological
process based on the analysis of the data of
endoscopic examination of the nasal cavity, CT of the
nose and adjacent nasal cavities, performed functional
examinations, maximum preservation of the mucous
membrane of the nose and cavities, anatomical bone
structures , correcting their configuration, a treatment
plan aimed at restoring the lost functions is being
determined. In recent years, a lot of data on functional
endonasal preventive operations have been collected.
Strong curvature of the nasal septum is one of the
most common local factors associated with the lateral
pathology of the nasal cavity. Disruption of nasal
breathing leads to changes in mucociliary clearance
and creates conditions for inflammation in PNS. In this
regard, there is a need to sanitize the center of chronic
infection and anatomical correction of nasal
structures. Modern medical achievements allow to
expand the scope of joint surgical practices. In the
literature, there are pathological processes in the area
of the nasal septum, deformations of the structures of
the lateral wall of the nasal cavity, and the natural
opening of the nasal cavities; perforative odontogenic
maxillary
sinusitis;
issues
related
to
the
implementation of typical variants of joint operations
in the finger-like protrusions of the paranasal sinuses
combined with the damage of the orbit have not yet
been clarified [5-8]. Although in joint operative
practices, to one degree or another, injuries of the
mucous membrane occur in different areas of the nasal
cavity, the problem of prevention and treatment of
post-operative traumatic bleeding becomes extremely
important [4-12]. The hemostatic effect of tamponade
is, on the one hand, a strong mechanical pressure on
the bleeding vessel, and on the other hand, keeping
the blood in the nasal cavity, which ensures faster
blood clotting and faster thrombus formation in the
vessel. However, this method of stopping bleeding
from the nose is quite traumatic for the mucous
membrane of the nasal cavity, causing its dysfunction
and causing significant pain in patients. Tampon
removal is also a painful process. In addition, the
presence of a gauze tampon in the nasal cavity is
accompanied by strong inflammatory changes of the
mucous membrane, accompanied by the appearance
of signs of intoxication. The purpose of the study is to
conduct a morphological study of the mucous
membrane of the nasal cavity in joint surgical
procedures. passes with the appearance of signs of
intoxication. The purpose of the study is to conduct a
morphological study of the mucous membrane of the
nasal cavity in joint surgical operations. passes with the
appearance of signs of intoxication. The purpose of the
study is to conduct a morphological study of the
mucous membrane of the nasal cavity in joint surgical
procedures.
Purpose of the research work:
Assessment of the state
of the nasal mucosa in the rhinocytogramm after
various surgical procedures.
THE RESULTS AND DISCUSSION
Research materials and methods in 2021-2022, 60
patients with diseases of the nose and paranasal
cavities were comprehensively examined and treated
at the otorhinolaryngology department of the
multidisciplinary clinic of the Tashkent Medical
Academy. Combined surgical procedures were
performed in these patients, and clinical and
morphological studies were conducted on the
effectiveness of hemostatic agents. In order to
determine the degree of influence of the tools used in
the nasal cavity on the nasal mucosa after nasal cavity
surgical procedures, a cytological study was conducted
in patients (table 1).
Volume 02 Issue 09-2022
34
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
02
I
SSUE
09
Pages:
32-37
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
OCLC
–
1121105677
METADATA
IF
–
5.654
Publisher:
Oscar Publishing Services
Servi
Table 1
In rhinopathologies, the state of the mucous membrane of the nasal cavity is on a rhinocytogramm
Signs
1 group (n=)
2 groups (n=)
3 groups (n=)
breath
papillary cellular
structures derived
from the epithelium
of the airways
Bef
o
re the
o
pe
ratio
n
Da
y 7
af
te
r
su
rg
ery
Da
y 14 af
ter
su
rg
ery
Bef
o
re the o
pe
ra
tio
n
Da
y 7
af
te
r
su
rg
ery
Da
y 14 af
ter
su
rg
er
y
Bef
o
re the o
pe
ra
tio
n
Da
y 7
af
te
r
su
rg
ery
Da
y 14 af
ter
su
rg
er
y
Basal cells
+
+
+
+
+
+
+
+
+
Scattered cells of
the respiratory
epithelium
-
-
-
-
-
+
+
+
+
Signs of
hypersecretion in
respiratory
epithelial cells
-
-
+
-
+
+
+
+
+
Degenerative-
destructive signs in
respiratory
epithelial cells
-
+
+
-
-
+
-
-
-
Metaplasia of
squamous cell
elements
-
-
+
-
-
+
-
-
+
Treatment
pathomorphosis
-
-
-
-
-
+
+
+
+
Cornification
-
-
+
-
+
+
-
+
+
Fibroblasts
-
+
+
-
+
+
+
+
+
segmented
neutrophils
-
-
+
-
-
+
-
+
+
Volume 02 Issue 09-2022
35
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
02
I
SSUE
09
Pages:
32-37
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
OCLC
–
1121105677
METADATA
IF
–
5.654
Publisher:
Oscar Publishing Services
Servi
Eosinophils
+
-
+
+
-
+
+
-
+
Lymphocytes
+
+
+
+
+
+
+
+
+
Histiocytes
-
-
+
-
+
+
+
+
+
Phagocytosis
-
-
+
-
-
+
+
+
+
Bacterial flora
+
+
+
+
+
+
+
-
-
As can be seen from the table data, the state of the
nasal mucosa was recorded in patients of each group
in the cytological material obtained from the mucous
membrane of the nasal cavity after the operation.
Thus, in patients who used gauze tamponade of the
nasal cavity (the first group), clear signs of
inflammatory infiltration and dystrophic changes were
detected. in the second group of patients, a
hemostatic sponge was used after surgery, and in this
group, in addition to the symptoms in the above group,
therapeutic pathomorphism was determined. Patients
in the third group (only the splint was used) were
distinguished by the reduction of inflammatory signs
and the presence of regenerative process signs, as can
be seen from the rhinocytogram of the mucous
membrane. Thus, the cytological examination of
smears taken from the mucous membrane of the nasal
cavity
taken
from
patients
with
various
rhinopathologies in the postoperative period showed
that nitric oxide leads to the disruption of intercellular
connections in the structure of polypous tissue and
slplint after surgery in group 3 patients with the help of
it led to the strengthening of the regenerative
processes of the mucous membrane of the nasal
cavity. The results of cytological studies have once
again confirmed the effectiveness of using the splint in
the practice of otorhinolaryngologists
Table 2
Description of the changes in the condition of the nasal mucosa 7 days after joint surgical procedures in the
nasal cavity in the studied groups of patients
Studied indicators (mean values)
1 groups
(p=50)
Gauze
tampon
2 groups
(p=50)
"Hemo
sponge"
3 groups
(p=50)
"Splint"
Mucous membrane
tumor
Strongly
developed
15
2
2
Not available
0
11
10
Average
5
2
5
Strongly
developed
14
1
4
Volume 02 Issue 09-2022
36
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
02
I
SSUE
09
Pages:
32-37
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
OCLC
–
1121105677
METADATA
IF
–
5.654
Publisher:
Oscar Publishing Services
Servi
Fibrinous vision
Not available
1
15
13
Average
7
3
3
Trophic changes
Strongly
developed
3
0
1
Not available
1
13
10
Average
4
2
2
Saccharin test indicators
(standard 6-8 min.)
29.4±3.1 min.
8.6±0.9 min.
11.8±0.7 min.
CONCLUSION
Changes in the surrounding anatomical structures of
the nasal septum specific to the type of curvature of
the nasal septum develop, changes in the functional
state of the nasal cavity with 3-4 and mixed types of the
nasal septum. mucociliary transport in joint
pathological conditions of tissues - 29.1 min, Ph-7.36,
absorption activity - 78.2, secretion activity - 49.3 mgr,
rhinomanometry - UHO - 295, UQ - 0.61 indicators were
determined. Therefore, it is advisable to correct the
nasal septum and anatomical structures located close
to it in patients; 3.
Experimental studies have
shown that collagen "Splint" does not have damaging
and local effects in the early stages. The effect of the
surrounding tissue on the sponge is insignificant and
non-inflammatory. Adhesion of collagen fibrils of the
sponge to the layers of mucous membrane structures
in the periphery of the study is observed in the late
periods of the study; Use of collagen "Splint" as an
alternative to gauze tamponade of the nasal cavity in
joint surgical procedures in the nasal cavity, volume of
complications during and after surgery in patients ,
made it possible to improve the results of treatment
due to strong trophic changes of the mucous
membrane and reduction of pain.
REFERENCES
1.
Arabyan, Jirayr Migranovich. Objektivnaya
otsenka
i
obsnovanie
hirurgicheskogo
meshetelstva
pri
sochetannoy
adenotonzillarnoy i rhinogennoy respiratory
chronic. Obstruktsii u detey. Diss. Yerevan
State Medical University named after M.
Geratsy, 2017.
2.
Kochergin, G. A., V. V. Dvoryanchikov, and F. A.
Syroezhkin. "Rehabilitation of patients with
vestibular disturbances posle simultannyx
rinootoxirurgicheskix vmeshatelstv." Russian
Rhinology 23.4 (2015): 29-33.
3.
Ermakova, M. V., K. O. Kurganova, and A. B.
Knyazev.
"Tselesoobraznost
simultannyx
operatsiy v rinologii." Bulletin of medical
internet conference. Vol. 5. No. 5. Obshchestvo
s ogranichennoy otvetstvennostyu "Nauka i
innovatsii", 2015.
4.
Palchun V. T., Magomedov M. M., Dibirova T. A.
USTROYSTVO DLYa OSTANOVKI NOSOVOGO
KROVOTECHENIya. - 2011.
5.
Boyko, N. V., A. S. Bachurina, and A. I. Zhdanov.
"Prophylaxis
of
postoperatsionnykh
krovotechenii
pri
adenotomii."
Russian
rhinology 23.2 (2015): 26-30.
Volume 02 Issue 09-2022
37
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
02
I
SSUE
09
Pages:
32-37
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
OCLC
–
1121105677
METADATA
IF
–
5.654
Publisher:
Oscar Publishing Services
Servi
6.
Boyko, N. V., and Yu. V. Shatokin.
"Pathogenesis of nosovykh krovotechenii and
bolnykh s arterialnoy hypertension." Journal of
Otorhinolaryngology 80.5 (2015): 41-45.
7.
Tarkova AR, Chernyavsky AM, Morozov SV,
Grigorev IA, Tkacheva NI, Rodionov VI.
Hemostatic material of local activity and the
basis of oxidized cellulose. SibNauchMedy
Journ. 2015;35(2):11-15.
8.
Conger, Andrew, et al. "Evolution of the
graded repair of CSF leaks and skull base
defects in endonasal endoscopic tumor
surgery: trends in repair failure and meningitis
rates in 509 patients." Journal of neurosurgery
130.3 (2018): 861-875.
9.
Kaur, J., et al. "A comparative study of gloved
versus ungloved merocel® as nasal pack after
septoplasty." Nigerian Journal of Clinical
Practice 21.11 (2018): 1391-1395.
10.
Li, Tiancheng, et al. "A comparative study on
the effects of vacuum nasal drainage and nasal
packing after septoplasty." Int J ClinExpMed
11.12 (2018): 13787-13791.
11.
Liao, Zhenpeng, et al. "Decreased hospital
charges and postoperative pain in septoplasty
by application of enhanced recovery after
surgery." Therapeutics and clinical risk
management ent 14 (2018): 1871.
12.
Thomas, Ike, et al. "A Novel Technique of Using
Sponge as Post-Operative Nasal Packing."
Bengal Journal of Otolaryngology and
HeadNeckSurgery 26.1 (2018): 2
