Authors

  • Mirzayev S.P.
    Tashkent Medical Academy, Uzbekistan
  • Jabborov N.N.
    Tashkent Medical Academy, Uzbekistan
  • Akhmedov S.E.
    Tashkent Medical Academy, Uzbekistan
  • Botirov A.J.
    Tashkent Medical Academy, Uzbekistan
  • Abdullaev U.P.
    Tashkent Medical Academy, Uzbekistan
  • Akhundjanov N.A.
    Tashkent Medical Academy, Uzbekistan

DOI:

https://doi.org/10.37547/ijmscr/Volume04Issue10-09

Keywords:

Sinusitis upper humerus cyst

Abstract

Upper jaw sinus cysts are a very common disease, often an accidental clinical find upon radiography and computed tomography of the paranasal sinuses. At the same time, there are few reports in the literature about the location of cysts in the frontal and ponal cavities. It is especially difficult to diagnose the cysts of the wedge-shaped cavity, as known radiographic arrangements do not allow them to be diagnosed. The problem of diagnosing paranasal sinus cysts was solved by implementing computed tomography into practice.


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ABSTRACT

Upper jaw sinus cysts are a very common disease, often an accidental clinical find upon radiography and computed

tomography of the paranasal sinuses. At the same time, there are few reports in the literature about the location of

cysts in the frontal and ponal cavities. It is especially difficult to diagnose the cysts of the wedge-shaped cavity, as

known radiographic arrangements do not allow them to be diagnosed. The problem of diagnosing paranasal sinus

cysts was solved by implementing computed tomography into practice.

KEYWORDS

Research Article

ASPECTS OF ETIOLOGICAL FACTORS OF CYST MAXILLO-FACIAL SINUSES

Submission Date:

October 02, 2024,

Accepted Date:

October 07, 2024,

Published Date:

October 12, 2024

Crossref doi:

https://doi.org/10.37547/ijmscr/Volume04Issue10-09


Mirzayev S.P.

Tashkent Medical Academy, Uzbekistan

Jabborov N.N.

Tashkent Medical Academy, Uzbekistan

Akhmedov S.E.

Tashkent Medical Academy, Uzbekistan

Botirov A.J.

Tashkent Medical Academy, Uzbekistan

Abdullaev U.P.

Tashkent Medical Academy, Uzbekistan

Akhundjanov N.A.

Tashkent Medical Academy, Uzbekistan







Journal

Website:

https://theusajournals.
com/index.php/ijmscr

Copyright:

Original

content from this work
may be used under the
terms of the creative
commons

attributes

4.0 licence.


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Sinusitis, upper humerus, cyst.

INTRODUCTION

Sinuses of odontogenic origin occupy a significant

place

among

inflammatory

diseases

of

the

maxillofacial region, and patients with odontogenic

maxillary sinusitis make up about 25.8% among patients

with inflammatory processes of the maxillary sinus and

about 7.6% of patients in maxillofacial hospitals, and

among dental and otolaryngological institutions - from

3 to 10% [2].

The disease is a serious general medical and economic

problem, as the majority of patients are young and

middle-aged people, and in recent years, there has

been an increase in the number of patients with

chronic obstructive pulmonary disease, ranging from

41% to 77% of all inflammatory processes in the

maxillary sinus [12, 17].

Depending on the etiology of the disease, rhinogenic,

odontogenic, traumatic and allergic sinusitis of the

upper jaw are distinguished. On average, one-third of

all maxillary sinusitis is represented by its odontogenic

forms [23, 34], which are mainly the result of prolonged

existence of a chronic peri-apical infection focus in the

area of small and large maxillary teeth (MZ) [4, 11] or

errors of doctors in the process of treatment and

removal of these teeth [3, 15, 17, 30].All of the above is

a pressing dental problem.

The purpose of this study is to analyze the current

state, epidemiology, etiology, and pathogenesis of

odotogenic maxillary sinusitis.

Despite the improvement of therapeutic and

diagnostic equipment, the frequency of CHF among

other inflammatory diseases of the maxillofacial region

increased from 4-4.2% in the 1970s to 7.6% in the 1990s,

and there is a steady trend towards an increase in the

number of patients with CHF in recent years [13, 21].A

statistical analysis conducted by F.I. Shulman (2003)

showed that over the period from 1997 to 2001, the

frequency of severe acute respiratory distress

syndrome (AVSR) developed as a result of filling

material penetration into the upper jaw cavity after

endodontic treatment of teeth increased tenfold,

indicating a significant impact of the iatrogenic factor

on the development and progression of this pathology.

According to literature data [5,9,35] 23.6 to 77.2% of

FVV are its perforated forms.

Depending on the etiology of the disease, rhinogenic,

odontogenic, traumatic and allergic sinusitis of the

upper jaw are distinguished. This division is conditional,

as rhinogenic upper jaw sinusitis, developed against

the background of acute respiratory disease, can lead

to exacerbation of the periapical focus of chronic


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odontogenic infection and secondary infection of the

upper jaw sinus mucosa [36]. Therefore, 62% of

patients with rhinogenic maxillary sinusitis exhibited

odontogenic infection foci [5, 24].

Emergency cases, like rhinogenic ones, are primarily

caused by a purulent infection. The leading infectious

agents are hemolytic streptococci, pneumococci,

staphylococci, as well as opportunistic intestinal

bacteria.

Several microbial agents, often a mixed flora: aerobic

flora: Staphylococcus anreus, Streptococcus Species,

Hemophylus influenrac, Pseudomonasaeru- ginosa,

Pseulomonas

mirabilis,

Moraxella

catarrhalis;

anaerobic non-clostridian flora: Bacteroidesiradillis,

Bacteroides melaninogenicus, Fusobacterium nucleus

peptococcus, Veptobacillus peptococcus; fungal flora:

Candida pss., Aspergilluss pp.

These microorganisms are sown in monoculture as well

as in various associations with each other - mainly

aerobic-anaerobic and bacterial-fungal [7, 22].

According to the literature, there are differences in the

microflora in different courses of the disease. S. Ziuzio,

W. Stepniewier (1980) found bacterial flora

predominantly homogeneous in acute sinusitis and

mixed in chronic sinusitis.

At the same time, it is important to identify the

microflora of the oral cavity and the upper jaw cavity

[27, 31].

Studies conducted by A. and Bogatov (1991) show that

the immediate cause of chronic periodontitis is often

acute and acute periodontitis (up to 50% of cases) or

various complications of therapeutic and surgical

interventions on teeth (up to 20% of cases).Radical

cysts and osteomyelitis of the dental cavities in contact

with the floor of the maxillary sinus are found in 13% of

cases with almost the same frequency. In his research,

A.I. Bogatov (2000) established that the source of

infection in the emergency room is often the first mol

(56.6% of cases). In a number of cases, premature or

poor sanitation of the oral cavity is a prerequisite for

the development of VVR.

Currently, there are numerous reports in the literature

regarding the development of VCH due to the

penetration of filling material into the VCH cavity after

endodontic treatment of upper jaw teeth (UJ) [3, 17,

29, 30].

One of the frequent causes of the development of VVR

is a cavity perforation, differing in etiology,

localization, size, and course. According to a number of

authors [12, 16, 35], the development of emergency

situations against the backdrop of existing guaranteed

communication occurs in 41.2% to 91.7% of cases. There

is information in the literature that the most frequent


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group of VCH sinus perforations occurs with the

removal of lateral VCH teeth [2, 5, 10]. In the literature,

the rarest causes of chronic kidney disease are delayed

eruption of third molars, as well as inflammation

around retinated and semi-retinated teeth [23]. There

are clinical facts indicating the development of VCR

after the operation to raise the bottom of the VCHP

with sub-intral augmentation [9, 33].

Patho-morphological changes in chronic obstructive

pulmonary disease generally correspond to the stages

of the inflammatory process: alterative-exudative,

productive, and fibrous. Due to the spread of infection

from the alveolar ridge of the tooth to the left

ventricle, there is mucous-purulent discharge,

irreversible morphological changes in the mucous

membrane and the formation of necrotic tissues [7, 13].

Later on the ciliary activity of the ciliary epithelium

suffers, i.e. it is blocked. Meanwhile, the average

number of functioning glands in the mucous

membrane is significantly reduced, and general and

local cellular immunogenesis is disrupted [22]. In the

development of the pathological process against the

background of CHD, there is constant irritation of the

mucous membrane of the oral cavity with oral fluid,

and the mucous membrane begins to react with

productive inflammation. This process is often

localized, affecting the lining only in the area of the

alveolar bucket, it occurs weakly, asymptomatically,

therefore it is not always diagnosed.

Factors of a general nature contribute to the

development of maxillary sinusitis (MS): a decrease in

the div's immunological reactivity, the impact of

adverse environmental conditions [13]. The prolonged

exposure of microorganisms, products and the vital

activity of isodontogenic lesions, as well as

autoinfection of the oral cavity, penetrating into the

oral cavity, play a certain role in reducing

immunological reactivity in the maxillary sinus after its

perforation.

Microbial effects on the whole organism and on the

already altered, pre-sensitized mucosa of the maxillary

sinus from the focus of odontogenic infection

determine

the

further

development

of

the

inflammatory process [24]. Chronic granulating and

granulomatous periodontitis contribute to the

development of odontogenic chronic periodontitis [24,

27].

The bone barrier between the IVC floor and the

pathological focus due to inflammation of the bone

tissue of the dental alveolus undergoes resorption, in

fact, the integrity of the IVC floor is disrupted, which

can occur long before the tooth is removed [26, 30, 32].

In the majority of patients with chronic modontogenic

perforating VCH with the presence of a persistent

fistula at the bottom of the maxillary sinus, thickening

and polypoid transformation of the maxillary sinus

mucosa are observed [1, 10, 20].


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According to S.Z. Piskunov and co-authors. (2004),

productive changes in the VCH membrane in chronic

odontogenic sinusitis, unlike rhinogenic ones, are

localized in the area of the alveolar cavity and the

anterior sinus wall at the initial stage.

It has been established that in odontogenic VCH with

puncture of the sinus floor, inflammatory changes of a

chronic nature are detected in the mucous membrane,

which may be caused by frequent exacerbations,

inflammation in the area of the peri-apical lesions of

the teeth adjacent to the floor of the VCH. Another

important factor influencing the development of VCHP

is the size and throughput of the VCHP natural joint.

According to modern concepts, this factor is leading in

the pathogenesis of sinusitis [18]. As a result of nasal

mucosal edema and VCHP, the permeability of the

natural opening of the nasal cavity is disrupted, and the

ventilation and drainage function of the nasal cavity is

reduced. With complete obturation of the oxygen

membrane, due to the absorption of oxygen by the

mucous membrane into the VCHP, negative pressure is

created, veins are dilated, and stagnation of the

mucous membrane occurs. This exacerbates the

swelling of the tissue. As a result of pressure drop,

hypoxia and hypercapnia, conditions are created for

the growth of aerobes and facultative anaerobes [14].

Thus, a vicious circle is formed that determines the

outcome of the disease. If it is not torn, irreversible

changes develop in the mucous membrane [8, 25, 28].

CONCLUSIONS

Thus, summarizing the above, the following

conclusions can be drawn:

Currently, VCH is one of the most common dental

diseases, one of the causes of which is a perforation of

the upper jaw due to errors in the technique of removal

and endodontic treatment of VCH premolaries and

molars, and it is a serious general medical problem, as

the majority of patients are of working age.

The main etiological factors in the development of

VCHD are bacterial and fungal microflora with diseases

of the upper jaw teeth (chronic periodontitis, radicular

cysts, pubic osteomyelitis, periodontitis), foreign

bodies in the VCHD and reconstructive operations on

the VCHD, as well as sensitization of the div.

Topographic anatomical relationships between VCH

and VCHP teeth are the prerequisites for the

development of VCHS.

REFERENCES

1.

Akhundjanov U. S. K. N. A., Djuraev A. Z. S. J. A.

INITIAL

STATE

OF

COCHLEOVESTIBULAR

FUNCTION IN PATIENTS WITH HD WITH CVD.

2022.

2.

Botirov A. J. et al. Clinical and morphological results

of xenografts to use in myringoplasty //The

International Tinnitus Journal.

2020.

Т. 24. –

№.

1.

С. 1

-6.


background image

Volume 04 Issue 10-2024

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International Journal of Medical Sciences And Clinical Research
(ISSN

2771-2265)

VOLUME

04

ISSUE

10

P

AGES

:

48-55

OCLC

1121105677
















































Publisher:

Oscar Publishing Services

Servi

3.

Boymuradov S. A. et al. RESULTS OF ELIMINATION

OF POST-TRAUMA DEFORMATIONS OF THE

FACIAL AND JAW AREA (LIPOFILLING) //Oriental

Journal of Medicine and Pharmacology.

2023.

Т.

3.

№. 02. –

С. 1

-13.

4.

Djuraev J. A. et al. MIGRAINE: BASIC PRINCIPLES

OF TREATMENT AND PREVENTION //International

Journal of Medical Sciences And Clinical Research.

2023.

Т. 3. –

№. 02. –

С. 88

-91.

5.

Djuraev J. A. et al. MODERN METHODS OF

TREATMENT OF VIRAL HEPATITIS //International

Journal of Medical Sciences And Clinical Research.

2023.

Т. 3. –

№. 02. –

С. 69

-75.

6.

Djuraev J. A. et al. POLYCYSTIC OVARY

SYNDROME: A MODERN VIEW ON THE PROBLEM

//International Journal of Medical Sciences And

Clinical Research.

2023.

Т. 3. –

№. 02. –

С. 83

-87.

7.

Djuraev J. A. et al. Results of Frequency Analysis

Distribution of Polymorphism Rs1800895 592c> A

In Il10 Gene among Patients with Chronic Polypoid

Rhinosinusitis //The International Tinnitus Journal.

2021.

Т. 25. –

№. 2.

С. 176

-180.

8.

Djuraev J. A. Prevalence of Allelic and Genotypic

Variants of Il4, Il10, Il12b and Tlr2 Gene

Polymorphism in Patients with Chronic Polypoid

Rhinosinusitis.

9.

Djuraev J. A., Fayozov S. F. Rhinoplasty In

Combined

Deformations

Of

The

Nose

//International Scientific and Current Research

Conferences.

2021.

С. 58

-59.

10.

Khasanov U. S. et al. A COMPLEX APPROACH TO

THE TREATMENT OF ACUTE SENSONEURAL

HEARING LOSS OF DIFFERENT GENES //Oriental

Journal of Medicine and Pharmacology.

2023.

Т.

3.

№. 02. –

С. 14

-25.

11.

Khasanov U. S. et al. BOLALARDA EKSUDATİV

OTITNI DAVOLASH USULI //Oriental Journal of

Medicine and Pharmacology.

2022.

Т. 2. –

№. 1.

С. 64

-80.

12.

Khasanov U. S. et al. INITIAL STATE OF

COCHLEOVESTIBULAR FUNCTION IN PATIENTS

WITH HD WITH CVD //The American Journal of

Medical Sciences and Pharmaceutical Research.

2022.

Т. 4. –

№. 01. –

С. 60

-73.

13.

Khasanov U. S. et al. METHOD FOR THE

TREATMENT OF EXUDATIVE OTITIS MEDIA IN

CHILDREN //Oriental Journal of Medicine and

Pharmacology.

2022.

Т. 2. –

№. 01. –

С. 64

-81.

14.

Khasanov U. S. et al. Results of audiometrical

indicators of cochlevestibular disorders in patients

with arterial hypertension disease //Oriental

Journal of Medicine and Pharmacology.

2023.

Т.

3.

. 02.

С. 26

-36.

15.

Khasanov U. S. et al. Results of audiometrical

indicators of cochlevestibular disorders in patients

with arterial hypertension disease //Oriental

Journal of Medicine and Pharmacology.

2023.

Т.

3.

№. 02. –

С. 26

-36.

16.

Khasanov U. S. et al. Results of frequency analysis

distribution of A1188C RS3212227 polymorphism in


background image

Volume 04 Issue 10-2024

54


International Journal of Medical Sciences And Clinical Research
(ISSN

2771-2265)

VOLUME

04

ISSUE

10

P

AGES

:

48-55

OCLC

1121105677
















































Publisher:

Oscar Publishing Services

Servi

the IL 12B gene among patients with chronic

rhinosinusitis polyposis //Oriental Journal of

Medicine and Pharmacology.

2022.

Т. 2. –

№. 01.

С. 104

-115.

17.

Khasanov U. S. et al. VESTIBULAR ANALYZATOR

TEST

RESULT

INDICATORS

OF

COCHLEOVESTIBULAR

DISORDERS

ON

THE

BACKGROUND OF ARTERIAL HYPERTENSION

//Oriental Journal of Medicine and Pharmacology.

2023.

Т. 3. –

№. 02. –

С. 37

-44.

18.

Khasanov U. S., Abdullaev U. P., Djuraev J. A.

Results of audiological examination in acute

sensorineural hearing loss of various genesis

//Oriental Journal of Medicine and Pharmacology.

2022.

Т. 2. –

№. 01. –

С. 24

-50.

19.

Khasanov U. S., Akhundjanov N. A., Djuraev J. A.

DYNAMICS OF HEARING DISORDERS IN PATIENTS

WITH ARTERIAL HYPERTENSION UNDER THE

INFLUENCE

OF

HYPOTENSIVE

THERAPY

//International Journal of Medical Sciences And

Clinical Research.

2022.

Т. 2. –

№. 10. –

С. 16

-20.

20.

Khasanov U. S., Djuraev J. A. The state of cerebral

hemodynamics in patients with deviation of the

nasal septum.

2022.

21.

Khasanov U. S., Khayitov O. R., Djuraev J. A. OF THE

STATE

OF

HEARING

AND

CEREBRAL

HEMODYNAMICS IN PATIENTS WITH DEVIATION

OF THE NASAL SEPTUM //НАУКА, КУЛЬТУРА,

ОБРАЗОВАНИЕ:

АКТУАЛЬНЫЕ

ВОПРОСЫ,

ДОСТИЖЕНИЯ И ИННОВАЦИИ. –

2021.

С. 185

-

187.

22.

Khasanov U. S., Khayitov O. R., Djuraev J. A.

Peculiarities of the state of hearing and cerebral

hemodynamics in patients with deviation of the

nasal septum //Impact Factor: 4.9.

2021.

С. 41.

23.

Kurbonov Y. K., Boymuradov S. A., Djuraev J. A.

Overview Of Comprehensive Treatment Of Acute

Purulent-Inflammatory Diseases Of The Face And

Neck //The American Journal of Medical Sciences

and Pharmaceutical Research.

2021.

Т. 3. –

№.

01.

С. 15

-23.

24.

Kurbonov Y. K., Boymuradov S. A., Djuraev J. A.

Purulent-Necrotic Diseases of The Face: Aspects of

Diagnostics and Treatment //The American Journal

of Medical Sciences and Pharmaceutical Research.

2021.

Т. 3. –

№. 01. –

С. 24

-30.

25.

Narmurotov B. K., Boymuradov S. A., Djuraev J. A.

Comparative

Characteristics

Of

Rheological

Properties Of Blood In Combined Face Injuries

Before And After Treatment //The American

Journal of Medical Sciences and Pharmaceutical

Research.

2021.

Т. 3. –

. 01.

С. 67

-75.

26.

Nigmatov I. O. et al. Features of the application of

fat tissue auto transplantation (Lipofiling) in

patients with deformities of the maxillofacial

region

//Academicia:

An

International

Multidisciplinary Research Journal.

2021.

Т.

11.

№. 1. –

С. 195

-204.


background image

Volume 04 Issue 10-2024

55


International Journal of Medical Sciences And Clinical Research
(ISSN

2771-2265)

VOLUME

04

ISSUE

10

P

AGES

:

48-55

OCLC

1121105677
















































Publisher:

Oscar Publishing Services

Servi

27.

Nigmatov I. O. et al. Post-Traumatic Defects And

Face Deformations: Features Of Diagnostics And

Treatment //The American Journal of Medical

Sciences and Pharmaceutical Research.

2021.

Т.

3.

№. 01. –

С. 55

-66.

28.

Normurodov B. K. et al. Prevalence and structure

of purulent inflammatory diseases of the

maxillofacial area //Central Asian Journal of

Medicine.

2020.

Т. 2020. –

№. 1. –

С. 116

-130.

29.

Saidakramovich K. U., Obidovich A. N., Zavkievich

S. A. EFFECT OF ANTIHYPOTENSIVE THERAPY ON

VESTIBULAR DYSFUNCTION IN PATIENTS WITH

ARTERIAL HYPERTENSION : дис. –

2023.

30.

Shaumarov A. Z. et al. Role of Hemostatic Agents in

Simultaneous Surgical Interventions in the Nasal

Cavity //Journal of Experimental and Clinical

Surgery.

2021.

Т. 14. –

№. 2. –

С. 175

-180.

31.

Shaumarov A. Z., Xasanov U. S., Djurayev J. A.

RESULTS OF FREQUENCY ANALYSIS OF DEFB1

GENE-44C/G

rs2412971

POLYMORPHISM

IN

DIFFERENT FORMS OF CHRONIC TONSILLITIS

//Central Asian Journal of Medicine.

2024.

№. 1.

С. 61

-68.

32.

Vokhidov U. N. et al. Paralytic stenosis of the

larynx: Patients surgical overview //International

journal of health sciences.

2021.

Т. 5. –

№. 3. –

С.

386-392.

33.

Джураев Ж. А. и др. РЕЗУЛЬТАТЫ АНАЛИЗА

ЧАСТОТЫ РАСПРЕДЕЛЕНИЕ ПОЛИМОРФИЗМА

RS1800895 592C> A В ГЕНЕ IL10 СРЕДИ БОЛЬНЫХ

С ХПРС //Universum: медицина и фармакология. –

2023.

№. 3 (97). –

С. 11

-16.

34.

Нормуродов Б. К. и др. Частота встречаемости и

структура гнойных воспалительных заболеваний

челюстно

-

лицевой области //Хирург. –

2020.

№.

7-8.

С. 73

-84.

35.

ШАУМАРОВ А. З. и др. Роль гемостатических

средств

в

одновременных хирургических

вмешательствах в носовой полости.

References

Akhundjanov U. S. K. N. A., Djuraev A. Z. S. J. A. INITIAL STATE OF COCHLEOVESTIBULAR FUNCTION IN PATIENTS WITH HD WITH CVD. – 2022.

Botirov A. J. et al. Clinical and morphological results of xenografts to use in myringoplasty //The International Tinnitus Journal. – 2020. – Т. 24. – №. 1. – С. 1-6.

Boymuradov S. A. et al. RESULTS OF ELIMINATION OF POST-TRAUMA DEFORMATIONS OF THE FACIAL AND JAW AREA (LIPOFILLING) //Oriental Journal of Medicine and Pharmacology. – 2023. – Т. 3. – №. 02. – С. 1-13.

Djuraev J. A. et al. MIGRAINE: BASIC PRINCIPLES OF TREATMENT AND PREVENTION //International Journal of Medical Sciences And Clinical Research. – 2023. – Т. 3. – №. 02. – С. 88-91.

Djuraev J. A. et al. MODERN METHODS OF TREATMENT OF VIRAL HEPATITIS //International Journal of Medical Sciences And Clinical Research. – 2023. – Т. 3. – №. 02. – С. 69-75.

Djuraev J. A. et al. POLYCYSTIC OVARY SYNDROME: A MODERN VIEW ON THE PROBLEM //International Journal of Medical Sciences And Clinical Research. – 2023. – Т. 3. – №. 02. – С. 83-87.

Djuraev J. A. et al. Results of Frequency Analysis Distribution of Polymorphism Rs1800895 592c> A In Il10 Gene among Patients with Chronic Polypoid Rhinosinusitis //The International Tinnitus Journal. – 2021. – Т. 25. – №. 2. – С. 176-180.

Djuraev J. A. Prevalence of Allelic and Genotypic Variants of Il4, Il10, Il12b and Tlr2 Gene Polymorphism in Patients with Chronic Polypoid Rhinosinusitis.

Djuraev J. A., Fayozov S. F. Rhinoplasty In Combined Deformations Of The Nose //International Scientific and Current Research Conferences. – 2021. – С. 58-59.

Khasanov U. S. et al. A COMPLEX APPROACH TO THE TREATMENT OF ACUTE SENSONEURAL HEARING LOSS OF DIFFERENT GENES //Oriental Journal of Medicine and Pharmacology. – 2023. – Т. 3. – №. 02. – С. 14-25.

Khasanov U. S. et al. BOLALARDA EKSUDATİV OTITNI DAVOLASH USULI //Oriental Journal of Medicine and Pharmacology. – 2022. – Т. 2. – №. 1. – С. 64-80.

Khasanov U. S. et al. INITIAL STATE OF COCHLEOVESTIBULAR FUNCTION IN PATIENTS WITH HD WITH CVD //The American Journal of Medical Sciences and Pharmaceutical Research. – 2022. – Т. 4. – №. 01. – С. 60-73.

Khasanov U. S. et al. METHOD FOR THE TREATMENT OF EXUDATIVE OTITIS MEDIA IN CHILDREN //Oriental Journal of Medicine and Pharmacology. – 2022. – Т. 2. – №. 01. – С. 64-81.

Khasanov U. S. et al. Results of audiometrical indicators of cochlevestibular disorders in patients with arterial hypertension disease //Oriental Journal of Medicine and Pharmacology. – 2023. – Т. 3. – №. 02. – С. 26-36.

Khasanov U. S. et al. Results of audiometrical indicators of cochlevestibular disorders in patients with arterial hypertension disease //Oriental Journal of Medicine and Pharmacology. – 2023. – Т. 3. – №. 02. – С. 26-36.

Khasanov U. S. et al. Results of frequency analysis distribution of A1188C RS3212227 polymorphism in the IL 12B gene among patients with chronic rhinosinusitis polyposis //Oriental Journal of Medicine and Pharmacology. – 2022. – Т. 2. – №. 01. – С. 104-115.

Khasanov U. S. et al. VESTIBULAR ANALYZATOR TEST RESULT INDICATORS OF COCHLEOVESTIBULAR DISORDERS ON THE BACKGROUND OF ARTERIAL HYPERTENSION //Oriental Journal of Medicine and Pharmacology. – 2023. – Т. 3. – №. 02. – С. 37-44.

Khasanov U. S., Abdullaev U. P., Djuraev J. A. Results of audiological examination in acute sensorineural hearing loss of various genesis //Oriental Journal of Medicine and Pharmacology. – 2022. – Т. 2. – №. 01. – С. 24-50.

Khasanov U. S., Akhundjanov N. A., Djuraev J. A. DYNAMICS OF HEARING DISORDERS IN PATIENTS WITH ARTERIAL HYPERTENSION UNDER THE INFLUENCE OF HYPOTENSIVE THERAPY //International Journal of Medical Sciences And Clinical Research. – 2022. – Т. 2. – №. 10. – С. 16-20.

Khasanov U. S., Djuraev J. A. The state of cerebral hemodynamics in patients with deviation of the nasal septum. – 2022.

Khasanov U. S., Khayitov O. R., Djuraev J. A. OF THE STATE OF HEARING AND CEREBRAL HEMODYNAMICS IN PATIENTS WITH DEVIATION OF THE NASAL SEPTUM //НАУКА, КУЛЬТУРА, ОБРАЗОВАНИЕ: АКТУАЛЬНЫЕ ВОПРОСЫ, ДОСТИЖЕНИЯ И ИННОВАЦИИ. – 2021. – С. 185-187.

Khasanov U. S., Khayitov O. R., Djuraev J. A. Peculiarities of the state of hearing and cerebral hemodynamics in patients with deviation of the nasal septum //Impact Factor: 4.9. – 2021. – С. 41.

Kurbonov Y. K., Boymuradov S. A., Djuraev J. A. Overview Of Comprehensive Treatment Of Acute Purulent-Inflammatory Diseases Of The Face And Neck //The American Journal of Medical Sciences and Pharmaceutical Research. – 2021. – Т. 3. – №. 01. – С. 15-23.

Kurbonov Y. K., Boymuradov S. A., Djuraev J. A. Purulent-Necrotic Diseases of The Face: Aspects of Diagnostics and Treatment //The American Journal of Medical Sciences and Pharmaceutical Research. – 2021. – Т. 3. – №. 01. – С. 24-30.

Narmurotov B. K., Boymuradov S. A., Djuraev J. A. Comparative Characteristics Of Rheological Properties Of Blood In Combined Face Injuries Before And After Treatment //The American Journal of Medical Sciences and Pharmaceutical Research. – 2021. – Т. 3. – №. 01. – С. 67-75.

Nigmatov I. O. et al. Features of the application of fat tissue auto transplantation (Lipofiling) in patients with deformities of the maxillofacial region //Academicia: An International Multidisciplinary Research Journal. – 2021. – Т. 11. – №. 1. – С. 195-204.

Nigmatov I. O. et al. Post-Traumatic Defects And Face Deformations: Features Of Diagnostics And Treatment //The American Journal of Medical Sciences and Pharmaceutical Research. – 2021. – Т. 3. – №. 01. – С. 55-66.

Normurodov B. K. et al. Prevalence and structure of purulent inflammatory diseases of the maxillofacial area //Central Asian Journal of Medicine. – 2020. – Т. 2020. – №. 1. – С. 116-130.

Saidakramovich K. U., Obidovich A. N., Zavkievich S. A. EFFECT OF ANTIHYPOTENSIVE THERAPY ON VESTIBULAR DYSFUNCTION IN PATIENTS WITH ARTERIAL HYPERTENSION : дис. – 2023.

Shaumarov A. Z. et al. Role of Hemostatic Agents in Simultaneous Surgical Interventions in the Nasal Cavity //Journal of Experimental and Clinical Surgery. – 2021. – Т. 14. – №. 2. – С. 175-180.

Shaumarov A. Z., Xasanov U. S., Djurayev J. A. RESULTS OF FREQUENCY ANALYSIS OF DEFB1 GENE-44C/G rs2412971 POLYMORPHISM IN DIFFERENT FORMS OF CHRONIC TONSILLITIS //Central Asian Journal of Medicine. – 2024. – №. 1. – С. 61-68.

Vokhidov U. N. et al. Paralytic stenosis of the larynx: Patients surgical overview //International journal of health sciences. – 2021. – Т. 5. – №. 3. – С. 386-392.

Джураев Ж. А. и др. РЕЗУЛЬТАТЫ АНАЛИЗА ЧАСТОТЫ РАСПРЕДЕЛЕНИЕ ПОЛИМОРФИЗМА RS1800895 592C> A В ГЕНЕ IL10 СРЕДИ БОЛЬНЫХ С ХПРС //Universum: медицина и фармакология. – 2023. – №. 3 (97). – С. 11-16.

Нормуродов Б. К. и др. Частота встречаемости и структура гнойных воспалительных заболеваний челюстно-лицевой области //Хирург. – 2020. – №. 7-8. – С. 73-84.

ШАУМАРОВ А. З. и др. Роль гемостатических средств в одновременных хирургических вмешательствах в носовой полости.