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INFILTRATIVE-SUPPURATIVE TRICHOPHYTOSIS: CHARACTERISTICS OF
PROGRESSION AND TREATMENT METHODS
Saipova Nodira Sagdullaevna
Tashkent Regional Dermatology and Venereology Dispensary
Associate Professor, Department of Dermatology and Cosmetology, Doctor of Science (DSc)
Email:
Phone: +99893 378 51 28
Oydinova Munavvar O’ktam qizi
Tashkent Medical Academy
4th-Year Student, Faculty of Medicine No. 2
Email:
oydinovamunavvar2001@gmail.com
Phone: +99893 860 28 28
Abstract:
Infiltrative-suppurative trichophytosis is an infectious disease caused by dermatophytes
of the Trichophyton genus, characterized by deep involvement of hair and skin. This article
explores the etiology, clinical manifestations, diagnostic methods, and contemporary treatment
approaches for the disease. The study utilizes microscopic analysis, cultural examinations, and
clinical observations. The findings suggest that early diagnosis and comprehensive treatment of
infiltrative-suppurative trichophytosis are critical in preventing severe complications. Preventive
measures and strategies to curb the spread of dermatophytosis are also addressed.
Keywords:
infiltrative-suppurative trichophytosis, trichophytosis, dermatophytosis, fungal
infections, trichophytosis diagnosis, trichophytosis treatment, trichophytosis prevention,
Trichophyton.
1. Introduction
Trichophytosis is an infectious disease caused by dermatophytes, affecting the skin, hair, and nails.
It is particularly prevalent in rural areas and can be transmitted between humans and animals.
Infiltrative-suppurative trichophytosis, primarily caused by Trichophyton verrucosum and
Trichophyton mentagrophytes var. gypseum, is distinguished by its severe progression and the
need for prolonged treatment. This article highlights the clinical features, diagnostic approaches,
and modern treatment methods for the condition.
2. Research Problem and Relevance
Infiltrative-suppurative trichophytosis remains a significant issue in dermatology, particularly
among rural populations. In many cases, patients neglect the condition or attempt self-treatment,
leading to severe progression and long-term complications. Consequently, early detection and the
development of effective treatment strategies are of paramount importance.
3. Research Methodology
This study was conducted using clinical observations, microscopic examinations, and laboratory
analyses. The primary methods included:
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• Microscopic Examination: To identify the causative fungi of trichophytosis.
• Cultural Examination: To determine the specific species of dermatophytes.
• Clinical Observations: To evaluate the symptoms and treatment outcomes.
• Serological Tests: Used as an auxiliary tool for differential diagnosis.
.
4. Statistical Data
Accurate global statistics on infiltrative-suppurative trichophytosis are limited due to its relatively
rare occurrence and predominant reporting in rural areas. However, the following data highlight
general trends:
1. Prevalence:
• Globally, trichophytosis accounts for 20–30% of fungal infections. The infiltrative-suppurative
form constitutes approximately 5–10% of all trichophytosis cases.
• In Uzbekistan, trichophytosis is more common in regions with developed agriculture (e.g.,
Fergana, Samarkand, and Kashkadarya provinces). The annual incidence is estimated at 10–15
cases per 100,000 population (data are approximate due to incomplete registration systems).
• Children (aged 5–12 years) and adults engaged in livestock farming are the most affected
groups.
2. Transmission Dynamics:
• Approximately 70–80% of cases are associated with zoonotic transmission, particularly from
cattle and dogs.
• Incidence increases by 30–40% in humid and warm climates (summer and autumn months).
3. Treatment Outcomes:
• With timely treatment, complete recovery is observed in 85–90% of cases.
• The likelihood of progression to a chronic form is 5–10%, particularly when treatment is
delayed.
• Permanent sequelae, such as keloid scars or hair loss, are reported in 10–15% of patients.
5. Research Results and Discussion
5.1. Clinical ManifestationsIn the early stages, the disease presents with erythematous, swollen,
and inflamed lesions on the skin. Damage to hair follicles results in hair breakage, creating a
“clipped hair” appearance. Purulent discharge is observed from affected areas, and the disease
progressively leads to regional lymphadenopathy.
5.2. DiagnosticsDiagnosis is established through microscopic and cultural examinations.
Examination under a Wood’s lamp allows differentiation between microsporia and trichophytosis.
5.3. Treatment MethodsThe following approaches are employed in the treatment of trichophytosis:
1. Systemic Treatment:
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• Antifungal Agents: Terbinafine, Griseofulvin, Itraconazole.
• Antihistamines: Clemastine, Loratadine.
• Hepatoprotectors: Essentiale Forte.
2. Topical Treatment:
• A mixture of iodine solution and ethyl alcohol (1:1), applied twice daily.
• Antifungal Ointments: Clotrimazole, Miconazole.
• Vitamin Therapy: To strengthen the immune system.
6. Conclusion
Infiltrative-suppurative trichophytosis is a severe condition that, if untreated, can lead to
significant complications. It is characterized by purulent infiltrates, hair loss, and distinct
inflammatory lesions. Treatment requires systemic and topical antifungal agents, supplemented by
adjunctive therapies. Statistical data indicate higher prevalence in rural areas and among
individuals involved in livestock farming. Preventive measures and early diagnosis are critical in
reducing the spread of the disease.
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