Currently, single studies of professional pastes for the removal of dental deposits have been conducted. The aim of the study is to conduct a comparative assessment of the clinical effectiveness of modem pastes for professional oral hygiene. The subject of the study was 5 types of pastes for professional oral hygiene: #1 - Cleanic (Kerr), #2 - Polyren #2 (Technodent), #3 - CleanPolish (Kerr), #4 Polydent # 2 (VladMiVa), #5 Vision (Willmann&Pein). After professional oral hygiene, normalization of clinical parameters in patients of group #1 (OHI-S-0.41 ±0.044; PHP -0.41 ±0.044; PFRI - 22.96±l.35) and group #2 (OHI-S-0.5±0.034; PHP-0.5±0.034; PFRI-24.74±1.23) was noted. According to the index evaluation data OHI-S, PHP and PFRI proved statistically significant effectiveness of pastes Cleanic (Kerr) and Polyren #2 (Technodent) in comparison with the control group (p=0.0001).