Students with learning disabilities (LD) often encounter an array of barriers when they start studying the field of science. Universal Design for Learning is a pedagogical framework that can address all needs of students with learning disabilities. This article includes qualitative and secondary data analysis to identify the potential benefits of UDL principles in improving the engagement of students with learning disabilities in the field of STEM education. This scientific research was conducted by analyzing scholarly articles regarding the implementation of the UDL method to meet the needs of all students with diverse educational backgrounds. By checking and analyzing several studies which have been carried out by professional researchers and pedagogues.