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QUALITY OF LIFE IN PATIENTS WITH VERTEBROGENIC PAIN SYNDROME.
Qodirov J.Sh.,
Mamadinova L.X.,
Mamasoliev Sh.M.
Department of Neurology, ASMI
Introduction.
Pain is one of the most important physiological phenomena that ensure the safety
of the div, the possibility of its rational and adequate interaction with the environment.
However, under the influence of various exogenous and endogenous factors that contribute to the
chronicity of pain, the mechanism originally evolutionarily designed for protection loses its
adaptive function and acts as a source of pathological changes in human functioning.
Keywords:
pain, intensity of pain syndrome, duration of pain syndrome, vertebrogenic etiology,
quality of life of patients.
The issue of studying pain of vertebrogenic etiology is currently receiving close attention due to
the increasing prevalence of this disease and the increase in the number of requests for medical
help. Prolonged pain in the spine has a negative impact not only on the physical aspect of a
person's activity, while reducing his ability to work, but also on the psychological and social
aspects, leading to the formation of persistent and pronounced disorders. Primary vertebrogenic
pain is usually associated with degenerative–dystrophic changes in the spine (dorsopathy,
spondylosis, and spondyloarthritis). Their development is influenced by genetic predisposition,
age, and risk factors. Degenerative-dystrophic changes lead to functional blockages and other
disorders of the biomechanics of the spinal column. This can provoke diseases of the internal
organs segmentally connected to the affected spine. But it should be borne in mind that the
internal organs do not have strict segmental innervation. For example, the stomach, liver,
kidneys, and pancreas receive innervation from the same celiac plexus.
All physiological and pathological reactions are not limited to just one segment, but move into
the zones of neighboring metameres. Due to the fact that spinal pathology causes multiple
disorders of nervous regulation and trophism of various internal organs, it can lead to the
development of functional disorders and organic pathology and cause somatic disease [4].
Dorsopathies are the most common cause of vertebrogenic pain. With infectious, oncological,
and traumatic lesions of the spine, secondary vertebrogenic pains occur. They are more often
caused by traumatic and infectious (spondylitis) diseases, ankylosing spondylitis (ankylosing
spondylitis), and less often by tumors and idiopathic spondylopathy (juvenile dorsal kyphosis or
disease Scheiermann—Mau.
Dorsopathies are a group of diseases of the musculoskeletal system and connective tissue, the
leading symptom complex of which is pain in the trunk and extremities of non-visceral etiology.
This disease is a serious problem all over the world.
Materials and methods:
32 patients (24 women, 8 men) with back pain who were treated in the
neurological department of the ASMI clinic from February to March 2025 were examined. The
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average age of patients was 58.3±9.2 years. Of these, 53% (17 people) were treated with
vertebrogenic lumboishialgia, 16% (5 people) with radiculopathy, 22% (7 people) with
cervicobrachialgia, 6% (2 people) with lumbalgia, 3% (1 person) with thoracalgia. The quality of
life was assessed on the SP-36 scale, the anxiety level was assessed on the Spielberger–Khanin
scale, and the pain intensity was assessed according to The scale is YOURS. Statistical
processing of the obtained data was carried out using the Statistica 7.0 program. The data are
presented in the form of median (Med) and interquartile range (LQ; UQ), where LQ is the 25th
percentile, UQ is the 75th percentile. The nonparametric Spearman rank correlation coefficient
was used to analyze the relationship between the features. The differences at p<0.05 were
considered statistically significant.
Results and discussion
. The pain intensity on the VAS scale was 6.4 (4; 8) points, which
indicates a moderate intensity of pain in most patients. When assessing the quality of life,
physical functioning amounted to 42.2 (0; 95.0) points, role functioning due to physical
condition – 7.8 (0.0; 50.0) points, pain intensity – 29.9 (0; 74.0) points, general health – 42.2
(20.0; 75.0) points, vital activity –38.1 (10.0; 85.0) points, social functioning – 44.5 (0; 87.5)
points, role functioning due to emotional state –22.9 (0; 100.0) points, mental health – 47.9 (12.0;
96.0) points.
The physical component of health, which is calculated from indicators of physical functioning,
role functioning due to physical condition, pain intensity and general health, amounted to 31.2
(17.8; 42.2) points.
The mental component of health, which consists of indicators of vital activity, social functioning,
mental health and role functioning due to emotional state, amounted to 36.9 (21.3; 62.2) points.
The data obtained indicate the predominance of low and medium the levels of quality of life in
the interviewed patients. So, the indicators are less than 50 points were found in the following
percentage of cases:
The physical component of health is 100%;
- Physical functioning -57%;
- role–based functioning due to physical condition - 100%;
- general state of health – 76%;
- mental component of health – 90%;
- vital activity – 84%;
- social functioning – 80%;
- role–based functioning due to emotional state - 81%;
- mental health – 62%.
When analyzing the level of reactive and personal anxiety using
The Spielberger–Khanin scale revealed that 100% of the respondents had a moderate to high
anxiety level: a high level of reactive anxiety – 73%, a moderate level of reactive anxiety – 27%;
The high level of personal anxiety is 88%, the average level of anxiety is 12%. In 56% of cases,
high levels of both personal and reactive anxiety were observed. The average values of reactive
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anxiety were 50.6 (34.0; 70.0) points, personal anxiety was 47.3 (14.0; 70.0) points.
During the correlation analysis, statistically significant There were significant correlations
between the severity of pain syndrome on the VAS scale and the level of personal anxiety
(p=0.025; r=0.67), as well as the severity of pain syndrome and the level of reactive anxiety
(p=0.022, r=0.95).
Conclusions.
The results obtained indicate the adverse effect of pain syndrome of vertebrogenic
etiology on the emotional and volitional sphere of human activity, leading to the development of
anxiety from moderate to high degrees, as well as significantly reducing the quality of life, social
and physical functioning.
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