“JOURNAL OF SCIENCE-INNOVATIVE RESEARCH IN
UZBEKISTAN” JURNALI
VOLUME 3, ISSUE 02, 2025. FEBRUARY
ResearchBib Impact Factor: 9.654/2024 ISSN 2992-8869
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Prospects of Using Radioactive Cement in the Treatment of Bone Cancer
Eshkaraev S.Ch.
Termiz University of Economics and Service, Termiz city, Farovon
massif, 4B house.
E-mail:
Xaitov Doston Bakhriddinovich
Termiz University of Economics and Service, Faculty of Medicine
Introduction:
Bone cancer is a serious and often challenging condition that can
severely affect the skeletal structure and the overall health of patients. Despite
advances in medical treatments, the management of bone cancer remains complex,
and current treatment options like surgery, chemotherapy, and radiotherapy often
have limitations in terms of targeting tumors and minimizing damage to healthy
tissues. Recently, the use of radioactive cement has emerged as a novel approach in
the treatment of bone cancer. Radioactive cement combines the benefits of localized
radiotherapy and mechanical stabilization, offering potential advantages for
improving treatment outcomes.
Radioactive cement is designed to deliver radiation directly to the tumor site
while simultaneously providing structural support to the affected bone. This
combination of therapeutic and supportive functions represents a significant
advancement in the field of bone cancer treatment. This thesis will examine the
prospects of using radioactive cement in treating bone cancer, evaluating its
potential benefits, challenges, and clinical applications, as well as exploring its role
in future treatment regimens.
Keywords:
polymethyl methacrylate, cement, kaolin, vertebroplasty,
kyphoplasty, radioisotopes, cesium-137, strontium-90.
Research Objectives:
The primary goal of this thesis is to explore the
feasibility and future prospects of using radioactive cement in the treatment of bone
cancer. The objectives include:
Analyzing the properties of radioactive cement and how they contribute to its
potential in treating bone cancer.
Investigating the clinical applications and outcomes of using radioactive
cement in real-world settings.
“JOURNAL OF SCIENCE-INNOVATIVE RESEARCH IN
UZBEKISTAN” JURNALI
VOLUME 3, ISSUE 02, 2025. FEBRUARY
ResearchBib Impact Factor: 9.654/2024 ISSN 2992-8869
171
Evaluating the advantages and potential drawbacks of this method compared to
conventional treatments.
Considering the future directions and research needed to optimize and expand
the use of radioactive cement in clinical practice.
IR spectroscopy.
The obtained composite material was analyzed using the
OVIRS brand IR spectrometer at the Physics Research Methods Laboratory of the
Chemistry Faculty of Termez State University. The chemical bonds between the
polymer matrix and components were studied. The IR spectra of kaolin filler, the
polymer matrix (PMMA), and radioactive cesium-137 are shown in
Figure 1.
Figure 1. IR Spectral Results of the RF-24 Radioactive Cement Composite.
The IR spectrum of the kaolin filler shows peaks up to approximately 500 cm⁻¹,
which may correspond to the Ti-O-Ti stretching vibration mode of the piezoceramic
structure. In the case of kaolin powder in dispersion in the respective solvent, we
can also observe the characteristic absorption band of the solvent at 2945 cm⁻¹. The
vibration characteristics of the CH group are observed at 2882 cm⁻¹ (asymmetric
stretching), the C=O bond is observed at 1686 cm⁻¹ (asymmetric stretching
vibration), and the CN bond is observed at 1305 cm⁻¹ (non-symmetric stretching
vibration). This fully explains the composition of the obtained composite.
“JOURNAL OF SCIENCE-INNOVATIVE RESEARCH IN
UZBEKISTAN” JURNALI
VOLUME 3, ISSUE 02, 2025. FEBRUARY
ResearchBib Impact Factor: 9.654/2024 ISSN 2992-8869
172
Conclusion:
The use of radioactive cement in the treatment of bone cancer
presents significant promise for improving patient outcomes by providing a targeted,
localized radiation therapy combined with mechanical stabilization. This dual
functionality makes it an attractive alternative or complement to traditional
treatment methods. However, further research and clinical trials are essential to fully
understand its efficacy, safety, and long-term benefits. With continued development,
radioactive cement may play a critical role in the future of bone cancer treatment,
offering new hope for patients and enhancing the effectiveness of current therapeutic
strategies.
