ANALYSIS OF THE DISBALANCE OF BIOCHEMICAL PARAMETERS AT VARIOUS STAGES OF CHRONIC KIDNEY DISEASE AND KIDNEY RECIPIENTS
Analysis of biochemical and electrolyte balance at various stages of chronic kidney disease and renal insufficiency.
The article describes the stages of chronic kidney disease (CKD) and the biochemical changes that occur in the body. Despite the fact that in recent years some authors have noted a significant decrease in mortality from cardiovascular diseases after kidney transplantation, cardiovascular diseases still account for more than 30% of all deaths observed in patients with functional kidney transplantation [11, 20]. Currently, special attention is being paid to improving the long-term results of TP. Prior to TP, patients on dialysis with end-stage SAD are constantly susceptible to cardiovascular diseases caused by uremic status and hemodialysis replacement therapy, as well as a number of factors. "Non-traditional" risk factors for the development of this cardiovascular disease include impaired phosphorus-calcium metabolism, volume loading, oxidative stress and chronic inflammation, protein and energy deficiency, hyperhomocysteinemia, etc. [13]. BT leads to the complete or partial elimination of many of these factors: in case of successful BT, phosphorus-calcium metabolism is normalized in most patients [12], hyperhydration and hyperkalemia are reduced when the excretory function of the kidneys is restored, contact of the patient's blood with the dialysis membrane during hemodialysis treatment is prevented, etc.