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MEDICINAL OF PLANTS CHRONIC IN CHOLECYSTITIS
IMPORTANCE
Nurova Nigora Sadilloevna
Bukhara state medicine institute family in medicine internal diseases
department assistant
https://doi.org/10.5281/zenodo.14500916
Conclusion
: Last ten year within , both local and international scale , food
digestion to do system functional violations treatment for new effective tools
current to grow with in treatment achieved to achievements despite , despite
roads system diseases appearance in being noticeable growth Pathologies
associated with the biliary tract and pancreas pose great challenges to modern
medicine, a trend that shows stability .
Key words :
diagnosis , prevention to take chronic cholecystitis ,
treatment ,
medicinal plants
Abstract
: This of the disease polyethological and pathogenesis
mechanisms abundance him/her to correct various approaches demand does .
Such without , naturally come output components own inside received herbal
remedies main therapy with together separately attention is worthy . Curcumin
farnesoid X receptor through from cholestasis protection to the effect yes , this
bile acid homeostasis to restore and inflammation reactions against to stand and
as a result cholestasis to decrease take comes . One row research this showed
that curcumin grass bubble reduction to the ability has . Many numerical various
kind useful features to the existence despite the fact that curcumin medical in
practice wide application close until then with its low bioavailability limited was
. Kavacurcumin such as biological existence high was forms synthesis made from
ex . use
Grass roads and stomach under diaper pathology modern medicine for
current is a problem . The last ten annually Pharmacological research both in
Uzbekistan and abroad at the market food digestion to do system functional
violations correction for new effective medicine of tools appearance to be with
related known therapeutic to success despite the disease increase trend being
observed . biliary from the system . From this except this trend stability with
separated It stands . So scientific to forecasts according to , the next 15-20 years
inside food digestion to do system diseases stress, dyskinetic , metabolic in the
world to diseases based diseases number increase on account of at least 30-50%
increases . mechanisms . There are chronic acalculous cholecystitis and chronic
calculous cholecystitis. Currently, the prevailing opinion is mainly about the
progressive development of gallbladder diseases. Functional motor-tonic
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disorders ( dyskinesia ) of the biliary tract, respectively, of a hyperkinetic
(hypertensive) or hypokinetic (hypotonic) type, occur with an increase or
decrease in tone. contractile (motor) activity of the gallbladder, often
contributing to stagnation, changes in physicochemical properties and infection
of bile in the gallbladder. A chronic inflammatory process develops, affecting its
mucous membrane and wall. In most cases, the formation of cholesterol,
bilirubin and mixed gallstones occurs, often accompanied by stony cholecystitis,
which is often diagnosed with gallstone disease . In most cases, it develops
against the background of a bacterial infection that enters the gallbladder by
enterogenic (ascending from the intestine), hematogenous (from foci of chronic
infection) or lymphogenous route. The development of the disease is facilitated
by stagnation bile in the gallbladder, mainly due to hypokinetic biliary
dyskinesia, anomalies in their development, a sedentary lifestyle (inactivity),
errors in nutrition (excessive consumption of fats and fried foods, easily
digestible carbohydrates, insufficient consumption of vegetable fiber, etc.), rare
meals, obesity, repeated pregnancies, constipation, etc. In the initial stage of
chronic cholecystitis, the inflammatory process, initiated by bacterial and other
flora, affects the mucous and submucosal membranes of the gallbladder. In the
future, inflammatory infiltration spreads to the entire gallbladder wall with the
development of connective tissue (fibrosis) and thickening of its wall; damage to
the serosa. The clinical picture of chronic cholecystitis consists of pain, dyspeptic
and neurotic syndromes. The nature of the pain depends to some extent on
dyskinesia of the common bile ducts: in the hypotonic variant it can be constant
or periodic, dull or aching, in the case of hypertension - short-term, more
intense, cramping. The pain is localized in the right hypochondrium and
epigastric region and can radiate to the right shoulder blade, collarbone,
shoulder and lumbar region. With the above-described irradiation, unbearable,
very strong, cramping pains in the right hypochondrium - biliary colic - are
characteristic of HCG and often occur as a result of blockage of the gallbladder
neck or extrahepatic bile ducts with stones. The pain syndrome is provoked by
the consumption of fatty, fried, smoked, spicy foods, carbonated drinks; heavy
physical exertion (lifting and lifting heavy loads, physical exercises with a bent
torso, etc.), div shaking (riding in shaking vehicles, etc.), psychoemotional
stressful situations. Dyspeptic syndrome is characterized by nausea, belching,
bitterness in the mouth, bloating, stool disorders (constipation or diarrhea) and
decreased appetite. Vomiting is very rare. Typical manifestations of neurotic
syndrome - conflict, inconsistency and a tendency to introspection. When
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examining the patient, it is often found that the sclera is subicteric and the
tongue is superimposed. With the help of palpation and percussion, pain points
and zones caused by irritation of the autonomic nervous system are identified.
The exacerbation of the disease is indicated by the presence of pain in the
gallbladder point (intersection of the right costal arch with the outer edge of the
rectus abdominis muscle), as well as pain in the area of attachment of the
gallbladder under the right shoulder blade. XI-XII ribs to the spine. They indicate
the presence of pain during palpation at the gallbladder point during breathing
or at the height of deep inspiration. Drug-free treatment provides for a rational
alternation of rest and physical activity (morning exercises, swimming, walks in
the fresh air, etc.), physiotherapy, phytotherapy, the use of mineral waters and
therapeutic nutrition. Usually, a 5-day schedule is prescribed with frequent (4-5
times a day) meals in small portions.
Diet therapy is an important component of treatment, helping to stimulate bile
secretion, reduce the activity of the inflammatory process in the gallbladder and
prevent the formation of stones. Frequent, fractional, mechanically and
chemically soft nutrition improves the emptying of the gallbladder by
stimulating its motor evacuation functions. Individual tolerance to food is taken
into account. The amount of fat in the diet is limited to a sufficient amount
(normal) of proteins and carbohydrates. Limit or limit the use of fatty, fried
foods, pickled and salty dishes, spicy spices, foods rich in cholesterol (salmon,
egg yolk, nuts,) An important component of treatment is helping to stimulate
bile secretion, reduce the activity of the inflammatory process. disrupts the
gallbladder and prevents the formation of stones. Frequent, fractional,
mechanically and chemically soft nutrition improves the emptying of the
gallbladder by stimulating its motor evacuation functions. Individual tolerance
to food is taken into account. The amount of fat in the diet is limited to a
sufficient (normal) amount of proteins and carbohydrates. Limit or limit the use
of fatty, fried, smoked and salty dishes, spicy spices, foods rich in cholesterol
(salmon, egg yolk, nuts, red and black caviar), cakes and pastries, creams,
alcoholic and carbonated drinks. They increase the proportion of vegetables and
fruits, vegetable oils (olive, sunflower, corn, etc.) with a normal diet. low-fat
meat, poultry, fish, dairy products - milk, cottage cheese, etc. The treatment of
chronic cholecystitis depends on the type of concomitant biliary dyskinesia, the
absence or presence of stones in the gallbladder and extrahepatic bile ducts, and
the severity of the disease. For a relatively mild clinical course of exacerbation,
short courses (5-7 days) of antibacterial therapy with tetracyclines
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(metacycline, doxycycline, etc.) and fluoroquinolone drugs (norfloxacin,
iprofloxacin, etc.), sulfonamides (biseptol, etc.), nitrofuran derivatives (furagin,
ercefuryl, etc.) are used for internal use. For a severe course of exacerbation,
fluoroquinolone
antibiotics
(levofloxacin,
pefloxacin),
cephalosporins
(ceftriaxone, ceftazidime, cefepime, etc.), aminoglycosides (amikacin,
tobramycin, etc.), semi-synthetic penicillins (amoxiclav, timentin, etc.) are
indicated for parenteral use. To eliminate bile stasis, drugs that enhance the
peristalsis of the biliary tract (olive oil, sea buckthorn, magnesia) are used.
Choleretics (drugs that increase bile secretion) are used with caution so as not
to increase pain and lead to an increase in stasis. During the period of
exacerbation of chronic uncomplicated cholecystitis, phytotherapy methods are
used for treatment: herbs (mint, valerian, dandelion, chamomile ), calendula
flowers. Exacerbation signs from decreasing and disease into remission from the
past then , magnesia , xylitol or sorbitol with tubes recommendation Chronic
cholecystitis phytotherapeutic therapy with tansy, yarrow , marshmallow,
yarrow prepared tinctures acceptance from doing consists of . Physiotherapy
used : reflexology , electrophoresis , SMT therapy , mud therapy and others
Balneological at resorts sanatorium treatment is displayed .
Conclusion:
The study sheds light on the use of traditional health systems in the treatment of
chronic diseases in Bukhara. Given the persistent mortality rates associated with
these diseases, there is a need for phytochemical and pharmacological studies
on various medicinal plant species. There is a need to expand access to
traditional medicine, especially in rural areas. In addition, endangered species
require special attention to ensure sustainable traditional phytotherapy
methods. The literature on the treatment of cholecystitis requires quality
improvement and evidence-based evaluation, and cognitive medicine serves as a
valuable additional evaluation tool.
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Author : Stilidi EI, gastroenterologist
