Оптимизация послеоперационного лечения для минимизации осложнений при лечении вентральных грыж

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Газиев, К. (2024). Оптимизация послеоперационного лечения для минимизации осложнений при лечении вентральных грыж. Профилактическая медицина и здоровье, 3(4), 27–32. извлечено от https://inlibrary.uz/index.php/preventive-medicine/article/view/85141
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Аннотация

Использование синтетических материалов для герниопластики у пациентов с послеоперационными вентральными грыжами (ПВГ) позволяет снизить частоту раневых осложнений. Однако успех хирургического лечения ПВГ зависит от правильной подготовки к операции, выбора оптимального метода аллопластики и эффективного ведения пациента в послеоперационном периоде.

Проанализированы результаты хирургического лечения 143 пациентов с ПВГ, прооперированных в период 2018-2022 гг. в Бухарском областном многопрофильном медицинском центре. Для герниопластики использовались полипропиленовые сетчатые имплантаты производства "Paha" (Турция). У 65 (45,4%) пациентов была выполнена пластика onlay, у 78 (54,5%) пациентов - пластика sublay. В раннем послеоперационном периоде общие осложнения отмечены у 7 (4,8%) пациентов, раневые осложнения - у 15 (10,5%), летальность составила 0,69%.

Для улучшения результатов хирургического лечения больных с ПВГ необходимо придерживаться некоторых рекомендаций. В предоперационном периоде полезным может быть комплексное обследование пациентов с составлением индивидуальной программы профилактики раневых, тромбоэмболических и легочных осложнений.


background image

Profilaktik tibbiyot va salomatlik

Профилактическая

медицина

и

здоровье

Preventive Medicine

and Health

Journal home page:

https://inscience.uz/index.php/preventive-medicine

Enhancing postoperative care to reduce complications in

ventral hernia surgery

Karim GAZIYEV

1

Bukhara State Medical Institute

ARTICLE INFO

ABSTRACT

Article history:

Received April 2024
Received in revised form

10 May 2024
Accepted 25 May 2024

Available online

15 August 2024

The use of synthetic materials for hernioplasty in patients

with postoperative ventral hernias (PVH) helps reduce the

incidence of wound complications. However, the success of PVH
surgical treatment depends on thorough preoperative

preparation, selecting the optimal alloplasty method, and

effective postoperative patient management.

An analysis of the surgical treatment outcomes for 143 PVH

patients operated on between 2018 and 2022 at the Bukhara
Regional Multidisciplinary Medical Center was conducted.

Polypropylene mesh implants produced by "Paha" (Turkey)

were used for hernioplasty. Of these patients, 65 (45.4%)

underwent onlay plasty, while 78 (54.5%) received sublay
plasty. In the early postoperative period, general complications

were noted in 7 patients (4.8%), wound complications in

15 patients (10.5%), and the mortality rate was 0.69%.

To improve surgical outcomes for PVH patients, specific

recommendations should be followed. A comprehensive

preoperative examination, combined with an individualized

program to prevent wound, thromboembolic, and pulmonary
complications, can be beneficial.

2181-3663

2024 in Science LLC.

DOI:

https://doi.org/10.47689/2181-3663-vol3-iss4-pp27-32

This is an open-access article under the Attribution 4.0 International
(CC BY 4.0) license (

https://creativecommons.org/licenses/by/4.0/deed.ru

)

Keywords:

postoperative ventral
hernia,

polypropylene mesh
implant,

prophylaxis of

complications,

recurrence of hernia.

1

PhD, Associate Professor, Bukhara State Medical Institute. Bukhara, Uzbekistan. E-mail: gazievku1970@gmail.com


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Profilaktik tibbiyot va salomlatlik

Профилактическая медицина и здоровье–

Preventive Medicine and Health

Issue

3

4 (2024) / ISSN 2181-3663

28

Ventral chirishlarni davolashda asorlarni kamaytirish

uchun operatsiyadan keyingi davolashni optimallashtirish

ANNOTATSIYA

Kalit so‘zlar

:

operatsiyadan keyingi

ventral chirishlar,

polipropilen torli implantat,

asorlanishlarning oldini

olish,

chirishning qaytalanishi.

Operatsiyadan keyingi ventral chirishlari (PVG) bo‘lgan

bemorlarda gernioplastika uchun sintetik materiallardan

foydalanish jarohat asorlari jadalligini kamaytirish imkonini

beradi. Biroq, xirurgik davolashning muvaffaqiyati operatsiyaga

to‘g‘ri tayyorlanishga, alloplastikaning optimal usulini tanlashga

va bemorni operatsiyadan keyingi davrda samarali yuritishga

bog‘liq bo‘lmaydi.

2018

2022-

yillar davrida Buxoro viloyati ko‘p tarmoqli

tibbiyot markazida amalga oshirilgan 143 nafar bemorni

xirurgik davolash natijalari tahlil qilindi. Gernioplastika uchun

«Paha» (Turkiya) ishlab chiqarilgan polipropilen torli

implantlardan foydalanilgan. Bemorlarda 65 (45,4%) onlay

plastikasi, 78 (54,5%) bemorlarda sublay plastikasi bajarildi.

Erta operatsiyadan keyingi davrda 7 (4,8%) bemorda umumiy

asorlar, jarohat asorlari 15 (10,5%) da ko‘rsatilgan, o‘lim hajmi

0,69% ni tashkil etgan.

Bemorlarni xirurgik davolash natijalarini yaxshilash uchun

ayrim tavsiyalarga mos bo‘lishi kerak. Operatsion oldingi

davrda jarohat, tromboembolik va engil asorlarning oldini olish

bo‘yicha yakka tartibdagi dasturni tuzgan holda bemorlarni

kompleks tekshiruvdan o‘tkazish foydali bo‘lishi mumkin.

Оптимизация

послеоперационного лечения

для

минимизации осложнений при лечении вентральных

грыж

АННОТАЦИЯ

Ключевые слова:

послеоперационные

вентральные грыжи,

полипропиленовый

сетчатый имплантат,

профилактика

осложнений,

рецидив грыжи

.

Использование

синтетических

материалов

для

герниопластики

у пациентов с послеоперационными

вентральными грыжами (ПВГ) позволяет снизить частоту

раневых осложнений. Однако успех хирургического лечения

ПВГ зависит от правильной подготовки к операции, выбора

оптимального метода аллопластики и эффективного ведения

пациента в послеоперационном периоде.

Проанализированы результаты хирургического лечения

143 пациентов с ПВГ, прооперированных в период

2018

–2022 гг. в Бухарском областном многопрофильном

медицинском центре. Для герниопластики использовались

полипропиленовые сетчатые имплантаты производства

"Paha" (Турция). У 65 (45,4%) пациентов была выполнена

пластика onlay, у 78 (54,5%) пациентов

пластика sublay.

В раннем послеоперационном периоде общие осложнения

отмечены у 7 (4,8%) пациентов, раневые осложнения

у 15 (10,5%), летальность составила 0,

69%.


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Profilaktik tibbiyot va salomlatlik

Профилактическая медицина и здоровье–

Preventive Medicine and Health

Issue

3

4 (2024) / ISSN 2181-3663

29

Для улучшения результатов хирургического лечения

больных с ПВГ необходимо придерживаться некоторых

рекомендаций. В предоперационном периоде полезным

может быть комплексное обследование пациентов с

составлением индивидуальной программы профилактики

раневых, тромбоэмболических и легочных осложнений.

INTRODUCTION

Currently, there is no doubt about the expediency of using additional materials in

the surgical treatment of patients with postoperative ventral hernias (POVH). Over the

last 30 years, the methods of prosthetic plasty of hernia gates using synthetic mesh

prostheses have become the most widespread. The use of these techniques allowed for a

relatively low incidence of wound complications (3.5-3.9%) [6].

At the same time, it has been established that incorrect selection of patients,

inadequate preoperative preparation, technical errors during surgery and errors of

patient management in the postoperative period can lead to the development of

complications in the early postoperative period in patients with POVH.

The aim of the work: is to determine the main methods of complications

prevention in the early postoperative period after prosthetic plasty with polypropylene

mesh implant. The work was performed in the clinic of faculty and hospital surgery of

Bukhara State Medical Institute (BukhMI) on the basis of the regional multidisciplinary

medical center of Bukhara in the period 2018-2022.

MATERIAL AND METHODS

During this time period, prosthetic surgeries for POVH were performed on

143 patients (mean age of patients

55.05 ± 1.36 years). Among the patients, there were

102 (71.3%) women and 41 (28.6%) men. According to the hernia protrusion size

according to the classification proposed by the European Society of Herniology (EHS),

adopted at the XXI International Congress of Herniologists in Madrid (1999), patients

with small (W1) and medium (W2) POVGs prevailed (Table 1).

The polypropylene mesh implant of the "Paha" company (Turkey) was used for

hernia gate plasty. In 65 (45,4%) patients onlay plastic surgery was performed, and in

78 (54,5%) patients the mesh implant was placed in the sublay position. In the early

postoperative period wound complications were noted in 15 (10,5%) patients (Table 2).

General postoperative complications occurred in 7 (4.8%) patients with POVH.

3 patients developed early adhesive intestinal obstruction, which was resolved

conservatively. 2 patients had acute tracheobronchitis and in 2 cases phlebothrombosis

of deep veins of the lower limbs occurred.

Table 1

Distribution of patients with postoperative ventral hernias by size of hernial

protrusion

(

п

=

143)

Hernia size

Number of patients

а

bs.

%

W1 (small)

< 4 cm

62

43,3

W2 (medium)

≥4

-10 cm

57

39,9

W3 (large)

≥10 cm

24

16,8

Total

143

100


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Профилактическая медицина и здоровье–

Preventive Medicine and Health

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Table 2

Structure of local (wound) complications in patients with postoperative ventral

hernias after alloplasty

Complication

Number of patients, abs.

Frequency of complications, %

Wound seroma

7

4,89

Wound hematoma

2

1,39

Lymphorrhea

1

0,69

Wound margin necrosis

1

0,69

Wound infiltrate

3

2,09

Wound suppuration

1

0,69

Total

15

10,5


Fatal outcome in the early postoperative period was observed in 1 (0.69%) patient

whose cause of death was pulmonary embolism (PTE).

RESULTS AND DISCUSSION

When analyzing the results of POVH treatment it was established that the

prevention of alloprosthetic complications should start at the preoperative stage.
Complex preoperative preparation is aimed at creating favorable conditions for
performing operations, preventing a significant increase in intra-abdominal pressure and
related complications in the early postoperative period. Assessment of external
respiratory function allows predicting the risk of developing high intra-abdominal
pressure during surgery. In the case of a decompensated state (GIEL less than 60%),
special preparation is necessary. It includes the use of a bandage in combination with
active breathing exercises and complex therapeutic exercises.

According to literature data, there is a reliable increase in the incidence of wound

complications of ventral hernias with a higher div weight of the patient [8]. According
to the results of our study, the average div mass index in patients with POVH was

32 ± 0.62 kg/m2. Overweight was observed in 82.6% of patients with POVH. One of the

tasks of the preoperative period is to reduce the patient's div weight. For this purpose,
the patients were trained in outpatient conditions together with a nutritionist.

The development of wound complications after alloprosthesis in patients with

POVH was started in the preoperative period. In the presence of pathologic changes
(diaper rash, skin excoriation) the preparation was carried out from 5 days to 2 weeks.
The anterior abdominal wall was treated daily with an antiseptic solution, physical
therapy was prescribed. According to many authors, antibiotic prophylaxis significantly
reduces the incidence of suppuration after alloplasty [13, 14, 17]. In our clinic it is carried
out according to the following scheme: 30-40 min before the operation amoxiclav 1.2 g
intravenously (intravenous) is administered.

The greatest danger for patients' life is pulmonary embolism and abdominal

compartment syndrome, lethality in this case can be up to 10% [3]. Prevention of
thromboembolic complications begins immediately before surgery. It includes elastic
compression of the lower extremities and anticoagulant therapy. Elastic compression
should be performed in all patients with POVH before transportation to the operating
room until full activation of the patient in the postoperative period. Low molecular weight
heparin (fraxiparin) was used for specific prophylaxis. The dosage depended on div


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Preventive Medicine and Health

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weight: up to 50 kg

0.2 ml subcutaneously, 50

69 kg

0.3 ml, more than 70 kg

0.4 ml

once. In the group of patients we studied there was one fatal outcome as a result of TELA.
This patient had a high risk of thromboembolic complications due to the presence of
obesity of III

IV degree, large size POVH, varicose veins of the lower extremities.

Prophylactic measures were carried out in the usual manner. In spite of this, a lethal
outcome occurred. Probably, in such category of patients it is necessary to be more
cautious in favor of surgery and in some cases conservative methods of treatment should
be limited. To predict the development of increased intra-abdominal pressure syndrome, it
is currently recommended to perform X-ray computerized hernio-abdominometry [2]. The
technique allows to assess the state of the abdominal wall, determine the volume of the
abdominal cavity and hernial protrusion, and plan the technique of the forthcoming plasty.

Intraoperative stage of prevention of early postoperative complications is the most

important and determines the success of surgery, as well as the quality of life of the
patient. Often POVH is combined with other pathologies of the anterior abdominal wall
requiring surgical correction. Thus, in 8 (5.6%) patients POVH was combined with
diastasis of rectus abdominis muscles, and in 23 (16%)

with sagging abdomen.

Diastasis elimination was performed by applying invaginating sutures to the vaginas of
the rectus abdominis by the Championeer method with simultaneous implantation of the
mesh prosthesis under the aponeurosis. In the presence of saggy abdomen,
abdominoplasty was performed.

The question of the necessity of draining the surgical wound is debatable. Some

surgeons question the necessity of wound drainage after alloplasty and consider it as one
of the factors that contributes to its suppuration [16]. We approach wound drainage in a
differentiated manner. In onlay plasty we necessarily drain the wound for no more than
4-5 days. In sublay plasty in patients with small and medium-sized hernias we refrain
from placing drains, we install them only in patients with obesity and with extensive
hernias.

Management of the early postoperative period also influences the results of

treatment. After alloprosthesis in patients with large and giant hernias we use prolonged
peridural analgesia, which is an effective method of prevention of intestinal paresis. In
this case, the pain syndrome is successfully controlled, which contributes to earlier
activation of the patient.

An important role in the diagnosis and prevention of wound complications is

played by ultrasound of the postoperative wound. In case of fluid accumulation of more
than 20 mm, seroma puncture under ultrasound navigation is performed.

The closed method of wound management avoided a high incidence of purulent

complications, which amounted to 0.69%.

CONCLUSION

Thus, to improve the results of surgical treatment of POVH using plasty with mesh

prostheses it is necessary to fulfill a number of recommendations.

1. In patients with POVH a comprehensive examination should be carried out in

the preoperative period to identify concomitant diseases and to correct disorders of the
functions of organs, systems and homeostasis indicators.

2. In patients with high surgical risk due to the probability of dysfunction of vital

organs and systems, thromboembolic complications and development of compartment
syndrome, it is advisable to limit conservative treatment (wearing a bandage).


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Профилактическая медицина и здоровье–

Preventive Medicine and Health

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4 (2024) / ISSN 2181-3663

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3. All patients with POVH should be prophylactically treated for thromboembolic

complications both before surgery and in the early postoperative period.

4. In the presence of abdominal diseases requiring surgical correction, it is

advisable to perform simultaneous surgery with the choice of optimal access.

5. The issue of drainage of the operation area should be approached in a

differentiated manner. It is advisable to install vacuum-aspiration systems for drainage in
case of significant detachment of subcutaneous tissue. The terms of drainage should be
short (within 4-5 days).

6. In the presence of fluid formations, the best is a closed method of treatment

puncture under ultrasound navigation.

REFERENCES:

1.

Titov V. V., Kalachev I. I., Timoshin A.D. Comparative evaluation of sub- and

nadaponeurotic plasty of the anterior abdominal wall in patients with postoperative

ventral hernias // Annals of Surgery. 2008. № 4. С. 56

-59. (in Russian)

2.

Khamdamov B.Z., Nuraliev N.A., Gaziev K.U., Teshayev Sh.J., Khamdamov I.B.

Experimental development of methods of local treatment of wound infection // Biologiya

va tibbiyot muammolari. 2020. №1, (116). –

С. 194

-200. (in Russian)

3.

Yagudin M. K. Alternative approaches to hernioplasty of postoperative ventral

hernias // Kazan. med. zhurn. 2003. №2. С. 121

-123.9. Busek J. et al. Retromuscular mesh

repair of a hernia in a scar according to Rives our first experience // Rozhl. Chir. 2005.
Vol. 84. P. 543-546. (in Russian)

4.

Celdran A. et al. The role of antibiotic prophylaxis on wound infection after mesh

hernia repair under local anesthesia on an ambulatory basis // Hernia. 2004. № 8. P. 20

-22.

5.

Hanna M., Dissanaike S. Mesh ingrowth with concomitant bacterial infection

resulting in inability to explant: a failure of mesh salvage // Hernia 2015; 19 (2): 339-344.

6.

Khamdamov B.Z., Dehonov A.T., Gaziev K.U., Khamdamov I.B., Khakimboyeva

K.A. Characteristics of the Immune Profile in Wound Infection in Patients with Diabetes
Mellitus.// American Journal of Medicine and Medical Sciences 2022, 12(4): 432-436

7.

Salameh J. R. et al. Role of biomarkers in incisional hernias // Am. Surg. 2007.

Vol. 73, № 6. P. 561

-567.

8.

Simchen T., Rozin R., Wax Y. The Israel Study of Surgical Infection of drains and

risk of wound infection in operations for hernia // Surg. Gynecol. Obstet. 1990. Vol. 170,

№ 4. P. 331

-337.

9.

Gaziev K.U. Adaptive approach in the treatment of elderly and senile patients

with postoperative ventral hernias. Journal of Pharmaceutical Negative Results, 4613

4616. https://doi.org/10.47750/pnr.2022.13.S07.574

10.

Gaziyev K. (2023). Features of the tactics of treatment in adult patients with

postoperative abdominal hernia. American Journal of Pediatric Medicine and Health Sciences,
1(4), 158

161. Retrieved from https://grnjournal.us/index.php/AJPMHS/article/view/275

11.

Gaziyev, K. U. (2023). Impact of Endocrine Disorders on the Results of Surgical

Treatment of Patients with Cholelithiasis of Elderly and Old Age. Central Asian Journal of
Medical and Natural Science, 4(1), 182-186. https://doi.org/10.17605/OSF.IO/4RZ7W

Библиографические ссылки

Titov V. V., Kalachev I. I., Timoshin A.D. Comparative evaluation of sub- and nadaponeurotic plasty of the anterior abdominal wall in patients with postoperative ventral hernias // Annals of Surgery. 2008. № 4. С. 56-59. (in Russian)

Khamdamov B.Z., Nuraliev N.A., Gaziev K.U., Teshayev Sh.J., Khamdamov I.B. Experimental development of methods of local treatment of wound infection // Biologiya va tibbiyot muammolari. 2020. №1, (116). - С. 194-200. (in Russian)

Yagudin M. K. Alternative approaches to hernioplasty of postoperative ventral hernias // Kazan. med. zhurn. 2003. №2. С. 121-123.9. Busek J. et al. Retromuscular mesh repair of a hernia in a scar according to Rives our first experience // Rozhl. Chir. 2005. Vol. 84. P. 543-546. (in Russian)

Celdran A. et al. The role of antibiotic prophylaxis on wound infection after mesh hernia repair under local anesthesia on an ambulatory basis // Hernia. 2004. № 8. P. 20-22.

Hanna M., Dissanaike S. Mesh ingrowth with concomitant bacterial infection resulting in inability to explant: a failure of mesh salvage // Hernia 2015; 19 (2): 339-344.

Khamdamov B.Z., Dehonov A.T., Gaziev K.U., Khamdamov I.B., Khakimboyeva K.A. Characteristics of the Immune Profile in Wound Infection in Patients with Diabetes Mellitus.// American Journal of Medicine and Medical Sciences 2022, 12(4): 432-436

Salameh J. R. et al. Role of biomarkers in incisional hernias // Am. Surg. 2007. Vol. 73, № 6. P. 561-567.

Simchen T., Rozin R., Wax Y. The Israel Study of Surgical Infection of drains and risk of wound infection in operations for hernia // Surg. Gynecol. Obstet. 1990. Vol. 170, № 4. P. 331-337.

Gaziev K.U. Adaptive approach in the treatment of elderly and senile patients with postoperative ventral hernias. Journal of Pharmaceutical Negative Results, 4613–4616. https://doi.org/10.47750/pnr.2022.13.S07.574

Gaziyev K. (2023). Features of the tactics of treatment in adult patients with postoperative abdominal hernia. American Journal of Pediatric Medicine and Health Sciences, 1(4), 158–161. Retrieved from https://grnjournal.us/index.php/AJPMHS/article/view/275

Gaziyev, K. U. (2023). Impact of Endocrine Disorders on the Results of Surgical Treatment of Patients with Cholelithiasis of Elderly and Old Age. Central Asian Journal of Medical and Natural Science, 4(1), 182-186. https://doi.org/10.17605/OSF.IO/4RZ7W