Theoretical background of the endemic icteroghemoglobinuria of the karakul sheep

It is known that in Uzbekistan there are widespread violations of the copper metabolism of Karakul sheep associated with both a deficiency and an excess of this element in their body. Both of these types of impaired copper metabolism are accompanied by serious pathological deviations, leading to a decrease in the productivity of Karakul sheep and often to their death. In Southwestern Kyzilkum, Karakul sheep constantly has a disease with signs of jaundice and blood urine