Авторы

  • N.S. Mamasoliev
    Andijan State Medical Institute and RRCEM AB, Andijan, Uzbekistan.
  • N.A. Kholikova
    Andijan State Medical Institute and RRCEM AB, Andijan, Uzbekistan.
  • B.A. Toshmatov
    Andijan State Medical Institute and RRCEM AB, Andijan, Uzbekistan.

DOI:

https://doi.org/10.71337/inlibrary.uz.tafps.51086

Аннотация

The purpose of the study is to identify and evaluate modern pharmacoepidemiological characteristics of bronchial asthma (BA) in the Fergana Valley region.


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THEORETICAL ASPECTS IN THE FORMATION OF

PEDAGOGICAL SCIENCES

International scientific-online conference

126

PHARMACOEPIDEMIOLOGY CHARACTERISTICS OF BRONCHIAL

ASTHMA IN FERGANA VALLEY REGION (BASED ON THE RESULTS

OF 20 YEARS OF MONITORING)

Mamasoliev N.S.

Kholikova N.A.

Toshmatov B.A.

Andijan State Medical Institute and RRCEM AB, Andijan, Uzbekistan.

https://doi.org/10.5281/zenodo.13120284

The purpose of the study

is to identify and evaluate modern

pharmacoepidemiological characteristics of bronchial asthma (BA) in the
Fergana Valley region.

Research

material

and

methods.

In

2001-2021,

pharmacoepidemiological monitoring was organized in the conditions of
Andijan. 1663 patients (594 men and 1069 women aged ≥18-90 years) with BA
treated at RRCEM AB were taken as subjects.

BA was diagnosed and monitored using GINA (2011) criteria,

pharmacotherapy alternatives were determined and assessed using a special
pharmacoepidemiological questionnaire.

Results and conclusions.

Mainly, the adult population uses drugs that are

based and recommended for use at the international level. They make up 99% of
all preparations. 4 types of ICS (beclazone ECO, budesonide, fluticasone or
flixotide) and nebulizer therapy are used purposefully and purposefully. The use
of inhaled glucocorticosteroids increased by 2.1%, the use of anti-leukotriene
drugs decreased by 6.9%, the prescription of short-acting β2 agonists decreased
by 1.2%, and the targeted use of basic anti-inflammatory drugs decreased by
0.9%.

In contrast, the use of drugs other than inhaled glucocorticosteroids has

increased over the past 20 years: long-acting β2 agonists (by 4.0%), inhaled
anticholinergics (by 7.5%), short-acting theophyllines (by 10.5%), and
combined antiasthmatic drugs (by 6.3%). Methylprednisolone, systemic
glucocorticosteroids, mucolytics, magnesium sulfate and antihistamines of the
2nd and 3rd generations were used as "auxiliary antiasthmatic drugs".
These data are of medical-economical and preventive importance.

References:

1. Ганиев Б.С. Распространенность, фактор риска, формакоэпидемиология
и инновация в профилактике бронхиальной астмы//Дисс…..доктора
филасофии по медицинским наукам (PhD) ….Андижан –2022. – Б 10,0.


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THEORETICAL ASPECTS IN THE FORMATION OF

PEDAGOGICAL SCIENCES

International scientific-online conference

127

2. Нарзуллаева Н.А. Факторы риска при тяжелой бронхиальной астмы //
Вестник ассоциации пульмонологов Центральной Азии. – Тошкент. – 2001.
– Вып.5 (№1-4)- С. 27-30.
3.Ненашева Н.М. Бронхиальная астма. Карманное руководство для
практических врачей//”АТМОСФЕРА”. – Москва. – 2011. С. 6.
4. European Lung white book. Occupational risk,factors. Available at: hitps: //
www. Erswhitebook. org/chopters/occupational risk –factors/ [Accessed: July 1,
2021].
5. Schulte P., Howard J. Genetic susceptibility and the setting of occupational
health standarts //Annu. Rev. Public. Health - 2011; 32-149-159.
6. Tao L, Shi B., Shi G, Wan H. Efficacy of sublingual immunotherapy for allergic
asthma:retrospective meta-analysis of randomized, double-blind and placebo
controlled trials //Clin Respir J. - 2014:8:192-205
7. Trivedi V., Apala D.R., Iyer V.N. Occupational asthma: diagnostic challenges
and management dilemmas // Curr. Opin. Plum. Med. – 2017; 23 (2): 177-183.

Библиографические ссылки

Ганиев Б.С. Распространенность, фактор риска, формакоэпидемиология и инновация в профилактике бронхиальной астмы//Дисс…..доктора филасофии по медицинским наукам (PhD) ….Андижан –2022. – Б 10,0.

Нарзуллаева Н.А. Факторы риска при тяжелой бронхиальной астмы // Вестник ассоциации пульмонологов Центральной Азии. – Тошкент. – 2001. – Вып.5 (№1-4)- С. 27-30.

Ненашева Н.М. Бронхиальная астма. Карманное руководство для практических врачей//”АТМОСФЕРА”. – Москва. – 2011. С. 6.

European Lung white book. Occupational risk,factors. Available at: hitps: // www. Erswhitebook. org/chopters/occupational risk –factors/ [Accessed: July 1, 2021].

Schulte P., Howard J. Genetic susceptibility and the setting of occupational health standarts //Annu. Rev. Public. Health - 2011; 32-149-159.

Tao L, Shi B., Shi G, Wan H. Efficacy of sublingual immunotherapy for allergic asthma:retrospective meta-analysis of randomized, double-blind and placebo controlled trials //Clin Respir J. - 2014:8:192-205

Trivedi V., Apala D.R., Iyer V.N. Occupational asthma: diagnostic challenges and management dilemmas // Curr. Opin. Plum. Med. – 2017; 23 (2): 177-183.