All articles - Optics
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Assefoetida l., by the method of high-performance liquid chromatographyUzbekistan is a country endowed with a variety of medicinal plants with strong potential for therapeutic application, Ferula assefoetida l. is called ferula is one of the most popular medicinal herbs. It is important active ingredient responsible for the biological activity of ferula, through the major activity is anti-inflammatory. This analysis was aimed to determine analysis compound of ferulic acids analysis using high performanceliquid chromatography (HPLC), LC-20 Prominence, Shimadzu, column C-18 250 х 4,6 mm, 5 mcm; acetonitrile: acetic acid: aqua bides as mobile phase, flow rate 1 ml/min and detection at 320 nm. Thus the analytical method using HPLC for ferulic acid were feasible for quantitative analysis. As a result of the research, the content of dry extract was 0,01% of the content of ferulic acid.
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Clinical and functional evaluation of the effectiveness of complex treatment of partial optic nerve atrophy
Catalog of abstractsPurpose of the study: to evaluate the results of complex therapy including retrobulbar catheterization and magnetic stimulation of the optic nerve in patients with ChASN of different genesis by studying clinical and functional features of the eye in this case.
Methods. 105 patients (155 eyes) with the diagnosis: partial optic nerve atrophy of different genesis (PAN) received conventional treatment, treatment with the method of retrobulbar catheterization, as well as with the method of retrobulbar catheterization in combination with MS for 10 days. The dynamics of OD indicators, visual field, electrophysiological studies, ophthalmoscopy and ultrasound Dopplerography were investigated.
Results. The analysis of the obtained data indicates that the effectiveness of the proposed methods of treatment depends on the degree of MN destruction, so the treatment is more effective in the 11th degree of ChASN. However, in the group of patients treated by the combined method the efficiency is equally high both at II and III degrees of ChASN.
According to the data of visual acuity dynamics in patients with II stage of Chasnosis in the course of treatment it follows that if in the group of patients treated by the traditional method the effect was observed only in 64,3% of cases, in the group of patients treated by the method of retrobulbar catheterization the efficiency was observed in 89,3%.
The dynamics of the ocular fundus state under the proposed methods of treatment due to the short period of observation (2-3 weeks) underwent the following changes: dilation of CAC vessels, reduction of capillary tortuosity, reduction of retinal edema, as well as the appearance of foveal and macular reflexes distinctness. The data of ultrasound Dopplerography indicate a significant improvement of hemodynamic parameters in the CAC in patients with ChASN of different genesis in early terms after treatment. Improvement of systolic pressure indices was noted. In each case of the examined patients the improvement of hemodynamic resistance index Ri towards normalization was revealed. Accordingly, there was a significant increase in diastolic pressure, indicating the strengthening of elastic-elastic properties of vessels under the influence of treatment.
In our opinion, the improvement of hemodynamic parameters after the course of the proposed method of treatment is associated with an increase in the volume of the microcirculatory channel in the area of direct influence on MN by retrobulbar catheterization and MS.
