Mualliflar

  • Zhumaeva D.R.

DOI:

https://doi.org/10.71337/inlibrary.uz.tinnint.95124

Kalit so‘zlar:

Key words: BI-RADS mammography ultrasound examination of mammary glands fibrocystic mastopathy.

Annotasiya

Resume. To make a correct diagnosis, it is necessary to have diagnostic criteria 
that  make  it  possible  to  accurately  prescribe  treatment.  Modern  requirements  for 
diagnostic  methods  are  accuracy,  high  information  content,  and  accessibility.  The 
article  discusses  the  BI-RADS  (Breast  Imaging  Reporting  and  Data  System) 
international  system  for  describing  and  processing  mammography  and  ultrasound 
data, which has been gaining interest in our country in recent years. The BI-RADS 
system is a good tool for determining the algorithm of management of patients with 
breast diseases. 


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MANAGEMENT OF PATIENTS WITH BREAST PATHOLOGY

ACCORDING TO BI-RADS CLASSIFICATION

Asian International University

Zhumaeva D.R.

Resume.

To make a correct diagnosis, it is necessary to have diagnostic criteria

that make it possible to accurately prescribe treatment. Modern requirements for
diagnostic methods are accuracy, high information content, and accessibility. The
article discusses the BI-RADS (Breast Imaging Reporting and Data System)
international system for describing and processing mammography and ultrasound
data, which has been gaining interest in our country in recent years. The BI-RADS
system is a good tool for determining the algorithm of management of patients with
breast diseases.

Key words:

BI-RADS, mammography, ultrasound examination of mammary

glands, fibrocystic mastopathy.


Introduction.

The problem of diagnosing breast diseases is related to the search

for the ideal technique. During clinical examination, manifestations of fibrocystic
fibrosis are found in 20% of women, during mammographic, echographic and
histological examinations - in 50% [1, 2].

I would like to have a diagnostic technique that makes it possible to make a

diagnosis as early, accurately, minimally invasively, highly informative, inexpensively
and accessible as possible. To date, the only correct tactic for effective diagnosis of
breast diseases is an integrated approach [3].

In recent years, our country has been increasingly interested in the international

system for describing and processing mammography and ultrasound examination
(ultrasound) of the breast – BI-RADS (Breast Imaging Reporting and Data System),
which is used in many countries.

Mammography is still the "gold standard" breast examination. However,

mammographic screening has certain limitations. First of all, about 20% of cancer
cases may be missed. This happens most often in young women due to the high density
of the mammary gland parenchyma. The attitude towards ultrasound, which was
previously perceived as an additional method, has now changed. Ultrasound can be
used to differentiate between benign and malignant processes. The main disadvantage
of ultrasound in the early detection of cancer is the inability to detect
microcalcifications. According to recent publications, modern equipment makes it
possible to detect microcalcifications in 70% of cases, and cancer in 90% [4].


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BI-RADS is the result of the joint work of leading scientific centers in the USA

[5]. The use of BI-RADS helps ensure that the results of each woman's radiation
examination are communicated to the attending physician in a clear form with a final
assessment of the detected changes in scores. This system indicates a specific plan for
further medical actions aimed at establishing a diagnosis and providing adequate care
to the patient [5].

The main value of the BI-RADS system for practical medicine is that it allows

you to determine the succession of doctors of different specialties and patient
management tactics. The description of the mammographic examination, complete and
high-quality completion of the protocol assumes: indication of indications for
mammography; brief description of previous screening studies; brief description of
medical history. If an ultrasound scan of the mammary glands was performed earlier,
it is necessary to indicate for what purpose. BI-RADS terminology in mammography
Types of mammary gland structure. According to the 2018 BI-RADS scale. the
determination of the type of structure of the mammary glands was based on the
measurement of total density, as a result of which it was accepted to include mammary
glands in the 1st category, which contained less than 25% of the fibrous-glandular
tissue, in the 2nd category - from 30 to 54%, in the 3rd – from 55 to 76%, by the 4th –
more than 78%. In 2021, the numerical designations of the types of breast structure
were replaced by alphabetic ones:

• a: adipose tissue prevails, mammography sensitivity is high;
• b: scattered areas of high-density fibrous-glandular tissue are identified (the

term "density" describes the degree of attenuation of X-ray radiation as it passes
through the gland);

• c: glands of uneven density, small bulky formations can be masked by dense

fibrous tissue;

• d: the glands are very dense, the sensitivity of the method is low. Three-

dimensional formations. Most pathological processes in the mammary gland are
accompanied by a thickening of the tissue and, accordingly, the X-ray image shows a
symptom of darkening. If there are these changes in 2 projections, we can talk about
volumetric formation (mass). If the darkening is visualized in 1 projection, we can only
talk about densification, and not about volumetric formation. When analyzing the
volume formation (darkening), attention should be paid to the shape, contour and
density.

Shape analysis:
• rounded or oval;
• lobular;
• incorrect.


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A rounded or oval shape is more typical for benign neoplasms. The irregular

shape is more common in malignant processes. The lobular form of the formation can
be present in both malignant and benign processes, reflecting the anatomical features
of tumor growth.

Contour Analysis:
• capsule availability;
• the presence of a rim of enlightenment;
• the clarity or indistinctness of the outline of the formation.
The capsule with rounded and oval nodular formations in the mammary gland is

clearly differentiated in the presence of adipose tissue in the structure of the seal.

Density analysis:
• low (comparable to adipose tissue);
• mixed (heterogeneity);
• high (higher than the density of the gland tissue itself or comparable to the

density of the gland tissue – isodense).

Of all the tumorous and tumoriferous processes, only adipose tissue can look

more transparent compared to the surrounding background of the breast. Therefore, the
diagnosis of lipomas, fatty cysts, galactocele, etc. is not difficult. High-intensity
darkening in the image causes any pathological process of a productive or exudative
order (benign tumor, cyst, breast cancer, sarcoma, etc. Darkening of heterogeneous
density is caused by the presence of fatty elements in the pathological focus and occurs
in fibroadenolipomas, leaf-shaped tumors, galactocele, hamartomas, and enlarged
lymph nodes. Asymmetry of breast tissue density. The asymmetric density of breast
tissue detected by mammography corresponds to both non-tumor processes
(asymmetric involution of breast tissue, post-traumatic and post-inflammatory
changes, adenosis) and tumor (breast cancer).To clarify the nature of the seal, it is
necessary to obtain additional sighting images and ultrasound.

Calcinates. The shape, size, quantity, and distribution of calcinates in various

diseases are very distinctive. By localization, lobular, ductal and stromal calcinates are
isolated in breast tissue. Lobular calcifications in most cases are a sign of benign
processes, primarily various hyperplastic and proliferative changes (adenosis,
sclerosing adenosis, cysts, fibrocystic mastopathy). Fibrocystic changes are
characterized by bilateral calcifications of the type of "cups" (tea cup).With an average
degree of hyperplasia and involutive changes in glandular tissue, scattered single
calcifications with clear, even contours (size from 0.5 to 1.0 mm) are detected. They
are the result of moderate cystic hyperplasia, which calcifies during the involution of
breast tissue. Glandular tissue atrophy leaves punctate calcinates evenly dispersed
within one or more lobes. They are determined mainly on a fatty background.


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Special attention should be paid to calcinates of the "cotton ball" type. These are

small-point different-caliber calcinates, grouped into separate "lumps". They can occur
both in a limited area and diffuse (i.e., over the entire breast tissue). The detection of
such calcifications requires histological verification, especially if they are located in a
limited area. Such calcinates are characteristic of sclerosing adenosis with or without
epithelial proliferation and for malignant processes such as non–palpable breast cancer.
Another variant of lobular calcifications is calcifications of the type of "crushed stone",
"broken needle", "arrowhead". These are calcinates with sharp, uneven edges, of
different shapes and sizes. Their detection causes difficulties in differential diagnosis,
and requires additional sighting, magnification, and histological confirmation.

Ductal calcifications are calcifications in the ducts detected on mammograms.

They can be divided into 2 types: very dense, fragmented, uneven calcinates like dotted
lines or worm–like lines (more than 1.0 mm in diameter), often repeat the topography
of the ducts of the entire lobe of the mammary gland, form continuous lines, ring-
shaped shadows (when calcium surrounds the duct - like a "rod"). Such calcifications
are characteristic of plasmocytic mastitis, ductal ectasia. In case of blurring,
indistinctness in the contours of such calcifications, and a decrease in size of less than
0.5 mm, differential diagnosis with intracurrent noninvasive breast cancer (ductal
carcinoma in situ) is necessary; • heterogeneous small dotted, worm-like, intermittent
calcifications of the "snake skin" type, characteristic of intracurrent noninvasive cancer
(ductal carcinomas in situ). Stromal calcinates are localized outside the glandular tissue
– in the walls of blood vessels, fibroadenomas, fatty cysts, and skin. Usually, such
calcifications do not cause difficulties in diagnosis. In most cases, they are large,
lumpy, shapeless, located in the peripheral areas of the neoplasm (size 1 mm or more,
the less dense central part is of the "rim" type). They occur in the area of fatty necrosis,
in ducts, small fibroadenomas and cysts.

Calcinates of the skin are found in the sebaceous glands. Many materials used in

cosmetic products are radiopaque (the most famous is aluminum, which is part of some
deodorants). With the peripheral location of "calcifications" extending to the armpit,
having a bizarre shape, you should ask the woman about the use of cosmetics.
Identification of calcifications of the arteries of the breast skin does not cause problems.
Calcifications are located in the artery wall, as a result of which the arteries become
visible on radiographs.

BI-RADS terminology in breast ultrasound, many of the terms used to describe

changes in ultrasound are similar to those for mammography, in particular those that
are necessary to describe the shape or edges of a bulky formation. The terms that are
specific for describing changes in ultrasound will be discussed below. Shape: oval,
round, lobed, irregular. Contours: clear, indistinct.


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Degree of echogenicity: anechoic, hypoechoic, hyperechoic, isoechoic, mixed

echogenicity. Type of mammary gland structure: homogeneous echogenicity with a
predominance of adipose tissue, homogeneous echogenicity with a predominance of
fibrous-glandular tissue, heterogeneous echogenicity. Echogenicity may be a factor
influencing the final category, but it is not highly specific in itself. Acoustic effects:
distal gain, acoustic shadow, mixed, no effects. Surrounding tissue: structural changes,
duct changes, skin and subcutaneous fat, cooper's ligaments, anterior and posterior
fascia. Vascularization: absent, defined by the periphery of the formation, diffuse.
Other signs: compressibility, mobility, orientation, etc.

Conclusion The use of the BI-RADS system ensures:
• standardization of terminology;
a unified system for evaluating and interpreting changes;
• systematization of tactics for managing patients with breast spathology,

including examination, adequate treatment, and dynamic monitoring;

• proven flow algorithm to ensure high-quality medical care;
• cost-effectiveness of medical care due to optimization of the patient

management algorithm

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ИДЕИ В МИРЕ

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Saloxiddinovna, X. Y., & Ne’matillaevna, X. M. (2024). FEATURES OF THE
STRUCTURE OF THE REPRODUCTIVE ORGANS OF THE FEMALE
BODY.

ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В

МИРЕ

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55

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49.

Хафизова, М. Н., & Халимова, Ю. С. (2024). ИСПОЛЬЗОВАНИЕ
ЧАСТОТНЫХ ОТРЕЗКОВ В НАИМЕНОВАНИЯХ ЛЕКАРСТВЕННЫХ
ПРЕПАРАТОВ

В

ФАРМАЦЕВТИКЕ.

ОБРАЗОВАНИЕ

НАУКА

И

ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ

,

55

(2), 172-178.

50.

Хафизова, М. Н., & Халимова, Ю. С. (2024). МОТИВАЦИОННЫЕ МЕТОДЫ
ПРИ

ОБУЧЕНИИ

ЛАТЫНИ

И

МЕДИЦИНСКОЙ

ТЕРМИНОЛОГИИ.

ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ

В МИРЕ

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(2), 165-171.

51.

Халимова, Ю. С., & Хафизова, М. Н. (2024). ОСОБЕННОСТИ СОЗРЕВАНИЕ
И ФУНКЦИОНИРОВАНИЕ ЯИЧНИКОВ.

ОБРАЗОВАНИЕ НАУКА И

ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ

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55

(2), 188-194.

52.

Халимова, Ю. С., & Хафизова, М. Н. (2024). КЛИНИЧЕСКИЕ АСПЕКТЫ
ЛИЦ

ЗЛОУПОТРЕБЛЯЮЩЕЕСЯ

ЭНЕРГЕТИЧЕСКИМИ

НАПИТКАМИ.

TADQIQOTLAR. UZ

,

40

(5), 199-207.

53.

Халимова, Ю. С., & Хафизова, М. Н. (2024). кафедра Клинических наук
Азиатский международный университет Бухара, Узбекистан.

Modern

education and development

,

10

(1), 60-75.


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Ta'lim innovatsiyasi va integratsiyasi

https://scientific-jl.com/

42-son_1-to’plam_Aprel -2025

ISSN: 3030-3621

191

54.

Халимова, Ю. С., & Хафизова, М. Н. (2024). КЛИНИЧЕСКИЕ
ОСОБЕННОСТИ ЗАБОЛЕВАНИЙ ВНУТРЕННИХ ОРГАНОВ У ЛИЦ,
СТРАДАЮЩИХ АЛКОГОЛЬНОЙ ЗАВИСИМОСТЬЮ.

TADQIQOTLAR.

UZ

,

40

(5), 240-250.

55.

Халимова, Ю. С., & Хафизова, М. Н. (2024). МОРФО-ФУНКЦИОНАЛЬНЫЕ
И

КЛИНИЧЕСКИЕ

АСПЕКТЫ

ФОРМИРОВАНИЯ

КОЖНЫХ

ПОКРОВОВ.

Modern education and development

,

10

(1), 76-90.

56.

Khalimova, Y. S. (2024). Features of Sperm Development: Spermatogenesis and
Fertilization.

American Journal of Bioscience and Clinical Integrity

,

1

(11), 90-98.

57.

Salokhiddinovna, K. Y., & Nematilloevna, K. M. (2024). MODERN
MORPHOLOGY OF HEMATOPOIETIC ORGANS.

Modern education and

development

,

16

(9), 50-60.

58.

Khalimova, Y. (2025). MORPHOLOGY OF PATHOLOGICAL FORMS OF
PLATELETS.

Modern Science and Research

,

4

(2), 749-759.

59.

Salokhiddinovna, K. Y., & Nematilloevna, K. M. (2025). MODERN
MORPHOLOGY OF HEMATOPOIETIC ORGANS.

Modern education and

development

,

19

(2), 498-508.

60.

Халимова, Ю. С., & Хафизова, М. Н. (2025). СОВРЕМЕННАЯ
МОРФОЛОГИЯ КРОВЕТВОРНЫХ ОРГАНОВ.

Modern education and

development

,

19

(2), 487-497.

61.

Халимова, Ю. С., & Хафизова, М. Н. (2025). ГИСТОЛОГИЧЕСКАЯ
СТРУКТУРНАЯ МОРФОЛОГИЯ НЕФРОНОВ.

Modern education and

development

,

19

(2), 464-475.

62.

Saloxiddinovna, X. Y., & Nematilloevna, X. M. (2025). NEFRONLARNING
GISTOLOGIK

TUZILISH

MORFOLOGIYASI.

Modern

education

and

development

,

19

(2), 509-520.

63.

Saloxiddinovna, X. Y., & Ne’matilloyevna, X. M. (2025). QON YARATUVCHI
A'ZOLARNING ZAMONAVIY MORFOLOGIYASI.

Modern education and

development

,

19

(2), 476-486.

64.

Xalimova, Y. (2025). MODERN CONCEPTS OF BIOCHEMISTRY OF BLOOD
COAGULATION.

Modern Science and Research

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4

(3), 769-777.


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Халимова, Ю. С., & Хафизова, М. Н. (2024). КЛИНИЧЕСКИЕ ОСОБЕННОСТИ ЗАБОЛЕВАНИЙ ВНУТРЕННИХ ОРГАНОВ У ЛИЦ, СТРАДАЮЩИХ АЛКОГОЛЬНОЙ ЗАВИСИМОСТЬЮ. TADQIQOTLAR. UZ, 40(5), 240-250.

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Khalimova, Y. S. (2024). Features of Sperm Development: Spermatogenesis and Fertilization. American Journal of Bioscience and Clinical Integrity, 1(11), 90-98.

Salokhiddinovna, K. Y., & Nematilloevna, K. M. (2024). MODERN MORPHOLOGY OF HEMATOPOIETIC ORGANS. Modern education and development, 16(9), 50-60.

Khalimova, Y. (2025). MORPHOLOGY OF PATHOLOGICAL FORMS OF PLATELETS. Modern Science and Research, 4(2), 749-759.

Salokhiddinovna, K. Y., & Nematilloevna, K. M. (2025). MODERN MORPHOLOGY OF HEMATOPOIETIC ORGANS. Modern education and development, 19(2), 498-508.

Халимова, Ю. С., & Хафизова, М. Н. (2025). СОВРЕМЕННАЯ МОРФОЛОГИЯ КРОВЕТВОРНЫХ ОРГАНОВ. Modern education and development, 19(2), 487-497.

Халимова, Ю. С., & Хафизова, М. Н. (2025). ГИСТОЛОГИЧЕСКАЯ СТРУКТУРНАЯ МОРФОЛОГИЯ НЕФРОНОВ. Modern education and development, 19(2), 464-475.

Saloxiddinovna, X. Y., & Nematilloevna, X. M. (2025). NEFRONLARNING GISTOLOGIK TUZILISH MORFOLOGIYASI. Modern education and development, 19(2), 509-520.

Saloxiddinovna, X. Y., & Ne’matilloyevna, X. M. (2025). QON YARATUVCHI A'ZOLARNING ZAMONAVIY MORFOLOGIYASI. Modern education and development, 19(2), 476-486.

Xalimova, Y. (2025). MODERN CONCEPTS OF BIOCHEMISTRY OF BLOOD COAGULATION. Modern Science and Research, 4(3), 769-777.

Муаллифнинг (муаллифоарнинг) энг кўп ўқилган мақолалари