DOI:
https://doi.org/10.71337/inlibrary.uz.universaljurnal.111214Kalit so‘zlar:
Mikrobiota Candida albicans disbioz antifugal himoya immun tizimi probiyotiklar ichak mikrobiotasi opportunistic patogenAnnotasiya
Ushbu maqolada inson organizmidagi mikrobiotaning Candida albicans
zamburug‘iga qarshi himoyaviy roli keng ko‘lamda tahlil qilingan. Candida albicans-opportinistik
patogen bo‘lib, odatda organizmda simptomlarsiz mavjud bo‘ladi, biroq muayyan sharoitlarda
invaziv infeksiyalarni keltirib chiqarashi mumkin. Sog‘lom mirobiota uning ko‘payishini
cheklovchi asosiy bilogik to‘siqlardan biridir. Maqolada mikrobiota tarkibi, funksiyalari va
Candida albicans bilan o‘zaro aloqalari ilmiy asosda yoritilgan. Shuningdek, antbiotiklar, stress
va boshqa omillar tufayli yuzaga keladigan disbioz holatlarining Candida albicans infeksiyalari
rivojlnishiga qanday ta’sir qilishi haqida ma’lumotlar berilgan.
Bibliografik manbalar
Iliev ID, Underhill DM. “Striking a balance: fungal commensalism versus pathogenesis.” Curr Opin Microbiol. 2013.
Mason KL, Erb Downward JR, Falkowski NR, et al. “Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad –spectrum antibiotic therapy.” Infect Immun. 2012.
Kohler JR, Casadevall A, Perfect J, “The spectrum of fungi that infects humans.” Cold Spring Harb Perspect Med. 2015.
Huffnagle GB, Noverr MC. “The emeriging world of the fungal microbiome.” Trends Microbiol. 2013.
Arumugum M, et al. “Enterotypes of the human gut microbiome.”Nature. 2011.
Neville BA, d’Enfert C, Bougnoux M-E. “Candida albicans commensalism in the gastrointestinal tarct,” FEMS Yeast Res. 2015.
Zhai B, et al. “High-resolution mycobiota analysis reveals dynamic intestinal translocation preceding invasive candidiasis.”Nat Med. 2020.
