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Volume-38_Issue-1_April-2025
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CLINICAL EPIDEMIOLOGY OF INTESTINAL
INFECTIONS AND YERSINIOSIS
Ostonova Gulrukh Sodikovna
Bukhara State Medical Institute
УДК 616:579.61.01
Abstract:
Yersiniosis is a disease caused by several types of enteropathogenic
Yersinia. It has an alimentary transmission route and manifests clinically with CNS
intoxication, dyspepsia, tonsillitis, lymphadenopathy, rash, and organ damage in
various organs. Data from the examination, diagnosis, and treatment of 120 children
aged 6 months to 14 years suffering from acute diarrheal disease from 2021 to 2023
were analyzed. While they formed the main study group, 40 children were examined
as a control group. All observed children underwent extensive continuous
examinations, including clinical, laboratory, biochemical, virological, and
immunological studies. Special attention was paid to their complaints, past and
concomitant diseases, causes of illness, duration of illness, and results of diagnostic
and early therapeutic measures.
Keywords:
Yersinia enterocolitica, source of infection.
Relevance:
The study showed that 250 children with acute diarrhea were
retrospectively analyzed, of whom 120 children were analyzed prospectively, forming
the main group in our study. Among our main group, 78 (65%) were children living
in rural areas, while 42 (35%) were children living in urban areas.
In studying the etiology of the disease in 120 patients with controlled intestinal
infections, the cause of acute diarrhea remained unidentified in some cases. Among
the identified cases, there were 34 cases of intestinal yersiniosis, 2 cases of
salmonellosis, 2 cases of shigellosis, and 2 cases of rotavirus infection.
Objective:
To study the epidemiological and clinical manifestations, as well as
the laboratory diagnosis of yersiniosis.
Materials and Methods:
120 children under observation were divided into three
subgroups according to age to study the nature of the disease:
Results and Discussion:
Subgroup 1 included 91 (75.8%) children aged 6 months to 3 years,
Subgroup 2 included 24 (20%) children aged 4 to 11 years,
Subgroup 3 included 5 (4.2%) children aged 12 to 14 years.
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Figure 1. Distribution of children with intestinal infections by age
Figure 1 presents the distribution of study materials considering the age and
gender of the pediatric patients under observation.
As seen in Figure 1, boys accounted for 44% of the examined children, while
girls made up 66%. It is noteworthy that in all studied age groups, regardless of
gender, the total number of girls predominated.
Explaining this pattern is much more challenging, as the underlying cause is
related to the biological and gender-specific characteristics of the pediatric div,
which are not yet fully understood. At the same time, more than half (75.8%) of the
examined children affected by intestinal infections were in the age group of 6 months
to 3 years (Figure 1).
It should be noted that this can be explained by the anatomical, physiological,
pathomorphological, and both local and general characteristics of the div, which are
typical for children affected by yersiniosis.
Figure 2. Distribution of children affected by yersiniosis by age and gender
75.8
20
4,2
6 от месячного возраста до 3-х
лет
4 возраст от 11 лет
12 возраст от 11 лет
0
5
10
15
6 от месячного
возраста до 3-х лет
4 возраст 11 лет
12возраст 14 лет
9
4
0
13
6
2
Мальчики
Қиз болалар
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When studying comorbidities in children with yersiniosis (Figure 2),
89
(74.1%) patients were found to have anemia, rickets, and hypotrophy. Among them,
rickets and hypotrophy were observed in 41 (34.1%) cases, hypotrophy and anemia
in 28 (23.3%) cases, and exudative-catarrhal diathesis in 23 (19.1%) cases. Anemia
was diagnosed in 19 (15.8%) children, while malnutrition was also noted in 19
(15.8%) cases. Paratrophy was found in 16 (13.3%) children, hereditary diseases in
12 (10%), chronic tonsillitis in 5 (4.2%), and NVSAD carriage in 5 (4.2%) cases.
Among the 34 children with controlled yersiniosis, 18 (53.0%) were diagnosed
with gastroenteritis, 8 (23.5%) with enteritis, and 8 (23.5%) with enterocolitis.
Clinical observations provided substantial evidence that the course of yersiniosis most
commonly manifests as gastroenteritis.
Conclusions:
The variety of intestinal infections, their complications, and clinical
manifestations are of particular interest to infectious disease specialists and
pediatricians. This diversity enables rapid diagnosis and the correct selection of
pathogenetic treatment approaches.
As shown in Table 2.5, among 34 children affected by controlled yersiniosis, 3
(8.8%) had a moderately severe course of the disease, while 24 (70.6%) suffered from
severe forms of the disease. The fact that the severity of the primary illness was due
to the slowed protective processes of the child’s div serves as an essential finding.
Among the 120 children suffering from controlled acute diarrheal disease, 34
(20.6%) had a mild course, 16 (8.8%) had a moderately severe course, and 80 (70.6%)
experienced a severe course of the disease.
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