ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
55
INTRAZONALITY OF GILBERT'S SYNDROME IN A COMPARATIVE
ASSESSMENTOF PROVOKING FACTORS IN THE POPULATION.
Ikromova F.A.
Bukhara State Medical Institute
https://doi.org/10.5281/zenodo.14050417
Relevance:
Gilbert's syndrome (JS) is the most common form of
hereditary pigmented hepatosis, which is spread among Europeans 2-5%,
Asians 3 %, Africans 36 %. The disease first appears in adolescence and young
age, 8-10times more often in males. Provoking factors are prolonged hunger,
physical exertion, frequent vomiting. Along with them, the role of
neuropsychiatric disorders is given an important place in the development of
the disease
Objective
: to study the features of the course of CS in the population with
a comparative assessment of provoking factors.
Materials and methods of research.
To achieve this goal, a group of
patients with SF was examined, consisting of 46 people, whose average age was
24.6±4.8 years. Of these, 29 people were represented by the male sex. In each
case of LVанамнестически, the specific type of factor that was mainly the sole
cause of relapse was carefully identified in the anamnestic history. The
diagnosis of SF was established based on the results of clinical, laboratory-
biochemical, and echographic studies. In some cases, they used provoking tests,
such as fasting, a phenobarbital test, etc.
Results.
According to the data obtained, the relapse of SF in the examined
individuals occurred mainly against the background of: physical exertion,
prolonged hunger, and mental trauma. As follows from the data, in more than
half of the cases, a relapse of LV was observed due to physical exertion. Hunger
provoked an exacerbation of the disease in 1/3 of the examined persons. Only
5% of patients relapsed as a result of various emotional disorders. It should be
noted that physical activity with a large superiority provoked an exacerbation of
the disease in persons of the predominantly male sex. The other two factors
consistently contributed to the recurrence of CS in the fairer sex. There was also
a difference in the rates of recurrent LV. Thus, in individuals with high physical
activity, the frequency of relapse of the disease was observed much more often
than in starving people and people with mental illness.
Conclusion:
based on the conducted studies, it can be concluded that provoking
factors have different effects on the frequency of relapse of LV. Among them, the
leading one is physical activity, which in more than half of cases contributes to
the exacerbation of the disease.
ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
56
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