ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
155
BIOLOGICAL RISK FACTORS FOR SPONTANEOUS MISCARRIAGE
Bekbauliyeva G.N.
Eshmuradova S.Sh.
Tashkent Medical Academy, Tashkent, Uzbekistan
https://doi.org/10.5281/zenodo.15343677
Summary: The study included 266 women who were divided into 2 groups:
166 women with early miscarriage (I - group) and 100 women who did not
experience miscarriage (II - control group)
Резюме: В исследование было включено 266 женщин, которые были
разделены на 2 группы: 166 женщин с невынашиванием в раннем сроке (I -
группа) и 100 женщин, у которых не наблюдалось невынашивание
беременности (II - группа контроля)
Xulosa. Tadqiqotga 266 ta ayol kiritilgan bo'lib, ular o'z navbatida 2
guruhga bo'lindi: 1-guruh 166 ta ayolda homila rivojlanmay qolishi kuzatilgan
va 2-guruhda 100 ta ayol homila rivojlanmay qolishi kuzatilmagan
Spontaneous non-pregnancy is one of the most urgent problems of
obstetrics, as it has not only medical, but also economic and social
character.Thanks to the Decrees and Resolutions of the President of our
Republic undertaken in recent years to reduce reproductive and perinatal
losses, there has been a significant reduction in these indicators. Meanwhile,
despite the reduction of perinatal losses, if a certain family cannot realize its
reproductive plans due to non-pregnancy, it is obvious that planning and
implementation of preventive measures in relation to these conditions should
take into account its causative factors.
The aim of the work was to study the causative factors of pregnancy non-
pregnancy.
Materials and methods of research. We examined 166 women with early
pregnancy failure (I - group) and 100 women who did not experience pregnancy
failure (II - control group). To identify the influence of factors on the occurrence
of miscarriage, we determined the role and the strength of influence (weight) of
each factor and on this basis modeled the degree of risk of spontaneous
miscarriage.
Results of the study. The bulk of women in groups I and II were in the most
active fertile age (20-29 years) and the age composition of both groups was
almost identical, except for 35-40 year olds, the proportion of whom in group I is
significantly higher (11.4±2.4%), and the relative risk of miscarriage in them
(RR = 2.85) is almost 3 times higher than the average.
ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
156
Among biological factors, the Ketle index (wk = 9.8) was significant in
miscarriage. The calculated relative density coefficient (RDC) showed that the
minimum risk of miscarriage (RDC = 0.55) is characteristic of a Ketle index less
than 20. As it increases, the risk of spontaneous abortion increases (correlation
coefficient Ã=+1.0), and in women with a Ketle index of more than 30, it is 5.4
times higher than the average and 10 times higher than the minimum risk. It is
noteworthy that there were 5 times more women with high Kettle index (more
than 30) in group I than in the control (p<0.05).
The overwhelming majority of women in group I (82.8±2.9%) had a height
below 165 cm. Among them there were 2 times more women with height below
155 cm (p<0.05). It turned out that the lower the height of women, the higher
the relative risk of miscarriage (correlation coefficient à = - 1.0): the minimum
risk - in women with height of 165 cm and above, and the maximum - in women
with height below 155 cm, and especially in women with height below 151 cm
(CR = 3.0).
Conclusions. Thus, women with low height and high Kettle's index are at the
highest risk of spontaneous miscarriage.
Literatures::
1.
Bekbauliyeva G.N., Rizaev Zh.A., Abdurayimova G.A. Prognosis of clinical
risk factors for spontaneous miscarriages // Journal of Theoretical and Clinical
Medicine. – 2023, No. 2. – P. 35–37.
2.
Djabieva A.A. Pregnancy and delivery outcomes in women with threatened
miscarriage in the first trimester / A.A. Djabieva, A.V. Djabiev, I.M. Ordiyants //
Bulletin of RUDN, Series: Medicine. – 2012, No. 6. – P. 66–77.
3.
Sultanova N.A. Early diagnosis of placental insufficiency in women with
reproductive losses in the Republic of Uzbekistan // New Day in Medicine –
2020, No. 4 (32). – P. 695–697.
