ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
55
CLINICAL-DIAGNOSTIC FEATURES AND COMPLEXITY OF
TREATMENT IN THE COMORBID COURSE OF PULMONARY
TUBERCULOSIS AND MALIGNANT TUMORS
Iskandarova.M.
Usmonov.X.
Bukhara State Medical Institute
The Republic specializes in phthisiology and pulmonology scientific and
practical medical center
https://doi.org/10.5281/zenodo.13729517
An oncologist diagnoses tuberculosis and oncological diseases, each clinician
has a clear form of the disease development, an epidemiologist treats it and treats it
adequately.
In this regard, mycobacteriology of tuberculosis and risks include the study by
a biologist of the exact characteristics, specific pathogens and tuberculosis, means
of precise exposure, specific characteristics diagnosed by modern molecular
geneticist, immunohistochemical methods at the same time, as in the case of
epidemiological and sanitary-epidemiological measures, the effectiveness of such
studies is of particular importance for the profession, especially for the treatment
of tuberculosis and related diseases.
Purpose:
to improve the effectiveness of diagnosis and complex methods of
treatment in the treatment of patients with comorbid pulmonary tuberculosis
and malignant tumors
Materials and methods:
analysis of the medical history of 135 patients
with comorbid exposure to malignant tumors and pulmonary tuberculosis
treated in stationary conditions. as pulmonary tuberculosis, comorbid in
combination with malignant tumors and pulmonary tuberculosis is a malignant
tumor from which, in order to achieve positive results in the treatment of
malignant tumors and pulmonary tuberculosis, all methods of diagnosis,
treatment and sanitary-epidemiological norms were used, in which, in principle,
("rules of infection control"), bacteriological (bacterioscopy, sowing and
molecular-genetic),
morphological
(cytological,
histological,
immunogistochemical) and modern methods of, MRT, positrion emission
tomography) materials taken.
Results:
75 (55.6%) patients with comarbide combined with poor quality
tumors and pulmonary tuberculosis formed the main group, while 60 (44.4%)
patients formed the control group. In the control group, 30 (22.2%) patients
were diagnosed with malignant tumors and the remaining 30 (22.2%) with
ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
56
pulmonary tuberculosis. 75 (100%) patients - in 47 (62.7%) cases-were found
to be sanitized-epidemiologically high-risk for those around them, meaning that
patients were isolating the Mycobacterium tuberculosis.
31 (41.3%) of patients were hospitalised directly at an oncological facility,
while the remaining 44 (58.7%) patients received inpatient treatment at a
phthisiatric facility.
TBM was found to be positive in 7 (22.6%) of the 31 patients who were
admitted to the oncological institution in primary, with the presence of
tuberculosis in the lungs confirmed in 3-24 days, on average in 8.9 days. In
patients undergoing treatment with pulmonary tuberculosis in a phthisiatric
clinic, the diagnosis of a poor-quality tumor was confirmed in 8-27 days, on
average 14.6 days. Focusing on the above data, patients with pulmonary
tuberculosis are admitted to an oncological institution - patients with active-
form tuberculosis with TMB separator in 22.6±2.3% of cases-to the stationary,
and patients with poor-quality tumors in the oncological stationary have a very
high risk of transmission of the tuberculosis process to patients who received
polycymotherapy, radio therapy (light),
In 17 (22.7%) cases out of 75 (100%) patients, no specific anti-tumor
treatment was carried out, but symptomatic treatment was carried out in order
to improve the quality of life. 58 (77.3%) patients were treated against the
tumor in the oncology station. Patients were treated according to the standards
established in the treatment of algae and OATB, with 47 (62.7%) patients being
allocated TMB, a special procedure was established for such a category of
patients.
Of the 47 (100%) patients who secreted TMB - 39 (83.0%) had a tumor
treatment, as 8 (17.0%) had a symptomatic treatment, as the disease was in a
late stage. In 12.1% of patients, polycymotherapy treatment was started in the
oncological institution before the treatment for tuberculosis, in 39.7% 10-day
and in 15.5% of patients 15-day anti-tuberculosis treatment was carried out,
followed by courses of anti-tumor treatment against the background of the
treatment for tuberculosis. The anti-tumor treatment was continued in a special
oncological hospital by isolating the MBT separator patient from the
surrounding area to a separate room with anti-tuberculosis drugs.
Conclusion:
the use of measures such as correcting the infectious control –
sanitary epidemiological situation in the treatment of patients who actively
secrete moss+grass comorbid, the patient isolates the patient from those around
him, the patient's sleeping room is quarsized 2 times a day, the room equipment
ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
57
is treated 2 times a day with a 0.5% chlorine solution, the patient and the
medical worker
Used literature:
1. Garshin V. G. Inflammatory epithelial growths, their biological significance and
relation to the problem of cancer. - St. Petersburg, - 2014.
2. Zhumaev M. F. the complexity of diagnosis and problems of treatment of
resistant forms of pulmonary tuberculosis in the southern regions of the
Republic of Uzbekistan // kand. diss. - Tashkent. – 2023. - pp. 22-33.
3. Usmonov I.X.,Iskandarova I.M. Marphological appearance in the field of
pathological process and the state of immune cells when comorbid of poor-
quality tumor and pulmonary tuberculosis// Academic research in modern
science. T 3 Issue 16, pp.121-124
4. Usmonov I.X.,Iskandarova I.M. Contemporary approaches to diagnosing and
treating pulmonary tuberculosis and malignant tumors // Solution of social
problems in management and economy. T 3 Issue 5, pp.62-65
5. Usmonov I.X.,Iskandarova I.M. The current state of diagnosis, treatment and
Prognosis of the comorbid course of malignant and lulmonary
tuberculosis(literature review) // Eurasian Journal of Medical and Natural
Sciences,3(11), 152-156
6.Usmanov I. H., Iskandarova I. M. clinical and diagnostic features of the
treatment and prevention of tuberculosis in children and adolescents / / Journal
of Humanities and Natural Sciences No.8(03),2024. Vol.1
