The urgency and relevance of the dissertation topic. According to the World Health Organization cerebral stroke is a major cause of mortality in developed countries, and in the structure of total mortality takes 2-3 position. The total number of patients with stroke or transient ischemic attacks in the anamnesis in the world more than 50 million. Ischemic stroke (IS) - Important medical and social problem and a major cause of hospitalization, disability and mortality in developed countries. In despite of the close attention of scientists and specialists around the world the problem of early diagnosis of ischemic stroke and adequate cerebral reperfusion remains topical.
The aim of research work is development of radial methods of prediction of ischemic stroke flow depending on neuroimaging and hemodynamic patterns in the acute phase of the disease.
The scientific novelty' of the research work is the following:
modified criteria of embologenic plaques;
studied "ultrasound morphology" of atherosclerotic plaques of carotid arteries in patients with ischemic stroke, modified criteria of embologenity of plaques;
demonstrated relationship between hemodynamics by the middle cerebral artery and the size of focus of brain lesions;
studied changes in echocardiographic parameters in patients with ischemic stroke;
suggested ultrasound criteria of acute and chronic occlusion of the internal carotid artery, and identified significant relationship between the nature of the occlusion and stroke outcome;
shown, that flow of ischemic stroke depends on the hemodynamic flow over the middle cerebral artery and cerebrovascular reserve indicators in the acute period;
developed criteria of radiation diagnosis, allowing to carry out more detailed selection of patients for thrombolysis.
It is revealed, that cardiac pathology and, in particular, the potential sources of embolism not correlated with flows of hemodynamics along the middle cerebral artery and the size of cerebral ischemia focus.
The algorithm of diagnostic procedures in acute ischemic stroke was proposed.
