Авторы

  • J.A. Botirov
    Andijan State Medical Institute, Uzbekistan
  • A.A. Sotiboldiev
    Andijan State Medical Institute, Uzbekistan
  • U.Ya. Ibragimov
    Andijan State Medical Institute, Uzbekistan

DOI:

https://doi.org/10.71337/inlibrary.uz.canrms.53570

Аннотация

Obesity is currently becoming a global health problem worldwide, as about 1.7 billion people are overweight [5;6]. According to WHO, about 7% of the world's adult population is obese, while in developed countries about a third of the population (33.3%) is overweight [1]. A direct relationship has been established between the increase in the prevalence of obesity and the growth in cases of type 2 diabetes. According to WHO, the likelihood of developing diabetes increases by 20% with an increase in BMI for every 1 kg/m2 [2;3].


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IMMEDIATE RESULTS OF MINI-GASTRIC BYPASS IN THE

TRADITIONAL WAY FOR OBESITY AGAINST THE BACKGROUND

OF TYPE 2 DIABETES MELLITUS

Botirov J.A.

Sotiboldiev A.A.

Ibragimov U.Ya.

Andijan State Medical Institute, Uzbekistan

https://doi.org/10.5281/zenodo.13892998

Relevance of the problem.

Obesity is currently becoming a global health

problem worldwide, as about 1.7 billion people are overweight [5;6]. According
to WHO, about 7% of the world's adult population is obese, while in developed
countries about a third of the population (33.3%) is overweight [1]. A direct
relationship has been established between the increase in the prevalence of
obesity and the growth in cases of type 2 diabetes. According to WHO, the
likelihood of developing diabetes increases by 20% with an increase in BMI for
every 1 kg/m

2

[2;3].

In most patients with obesity against the background of type 2 DM, mini-

gastrosurgery allows not only to reduce div weight, but also to normalize
carbohydrate metabolism starting from the early postoperative period [4].
However, the course of the early postoperative period (in the first 30 days after
mini-gastrosurgery) is often overshadowed by the development of
postoperative complications, including "adductor loop syndrome". Therefore,
the search for ways to solve the problem of obesity against the background of
type 2 DM is justified, because it is aimed at improving the results of surgical
treatment of obesity against the background of type 2 DM, which was the subject
of this study.

The aim of the study

is to improve the results of surgical treatment for

obesity associated with diabetes mellitus (DM-2) using laparoscopic mini-gastric
bypass surgery.

Material and methods of the study. The work is based on the results of a

retrospective and prospective analysis of patients with obesity associated with
type 2 diabetes mellitus (hereinafter referred to as DM-2) for the period 2023 to
2024 subject to surgical treatment in the private clinic "Sekhat" in Andijan and
in the third surgical department of the Clinic of the Andijan State Medical
Institute.


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The subject of this study was 177 patients with obesity associated with type

2 diabetes. According to the purpose and objectives, the patients under study
were conditionally divided into two groups:

- comparison group - (2023) - 49 (27.7%) patients who underwent a

retrospective analysis of the results of surgical treatment in compliance with
traditional approaches;

- main group - (2024) - 128 (72.3%) patients who underwent a prospective

study of the results of surgical treatment using optimized surgical tactics.

The standard of examination of the studied patients before bariatric

intervention consisted of an assessment of physical parameters with the
implementation of laboratory, instrumental and statistical research methods in
accordance with the latest clinical guidelines (Dedov I.I. et al., 2018 and
protocols approved by the Ministry of Health of the Republic of Uzbekistan.

Results and discussion.

All postoperative complications are conditionally

divided into:

1)

complications directly related to the bariatric surgery (specific

complications) - anastomotic suture failure, afferent loop syndrome,
hypoglycemic syndrome, diarrhea, gastroesophageal reflux;

2)

wound - infiltrate, suppuration of the postoperative wound, ligature

fistula;

3)

complications not related to the bariatric surgery, which may also

occur in other surgeries (general complications).

In the comparison group, after laparoscopic mini-gastroshunting surgery

performed by the traditional method, complications associated with bariatric
surgery were noted in 9 (18.4%) patients. Of these, with the first degree of
obesity against the background of type 2 DM - in 4 (8.2%) cases, with the second
- in 3 (6.1%) and with the third - in 2 (4.1%) cases.

In the comparison group, after laparoscopic mini-gastroshunting surgery

performed by the traditional method, wound complications (purulent-septic)
were noted in 6 (12.2%) patients. Of these, with the first degree of obesity
against the background of type 2 DM - in 1 (2.0%) cases, with the second - in 2
(4.1%) and with the third - in 3 (6.1%) cases.

In the comparison group, after laparoscopic mini-gastroshunting surgery

performed in the traditional way, general complications were noted in 5
(10.2%) patients. Of these, with the first degree of obesity against the
background of type 2 DM - in 1 (2.0%) cases, with the second - in 2 (4.1%) and
with the third - in 2 (4.1%), with a fatal outcome in 1 (2.0%) case.


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Summary

. The analysis conducted in the comparison group showed that

after performing laparoscopic mini-gastroshunting surgery in the traditional
way, out of 9 (18.4%) complications directly related to the bariatric surgery, in 7
(14.3%) cases the cause was the development of afferent loop syndrome. This
circumstance prompted us to conduct a detailed analysis and develop a
preventive measure.

References:

1.

Galimov O.V., Khanov V.O., Sagitdinov R.R. Surgical treatment of

cholecystitis in patients suffering from obesity / O.V. Galimov, // Surgeon. -
2018. - No. 9-10. - P. 13-17.
2.

Dedov I.I., Melnichenko G.A., Shestakova M.V. et al. National clinical

guidelines for the treatment of morbid obesity in adults. 3rd revision
(Treatment of morbid obesity in adults). Obesity and metabolism. - 2018. - T. 15.
- P. 53-70.
3.

Kornyushin O.V., Toropova Ya.G., Neimark A.E. et al. Mechanisms of

influence of bariatric surgeries on the course of non-alcoholic fatty liver disease.
Experimental and Clinical Gastroenterology. 2017. 146 (10): 61-73.
4.

Neimark M.I., Pantyushin A.A., Zhilin S.V. Effect of mini-gastrosurgery for

morbid obesity on carbohydrate metabolism parameters. Medical alphabet.
2022; (30): 37–40.
5.

Uspensky Yu.P., Petrenko Yu.V., Gulunov Z.Kh. et al. Metabolic syndrome.

Study guide. – St. Petersburg, 2017. – p 60.
6.

Fried M. Et al. Interdisciplinary European guidelines on metabolic and

bariatric surgery. International Federation for the Surgery of Obesity and
Metabolic Disorders - European Chapter (IFSO-EC) and European Association
for the Study of Obesity (EASO) //Obes Surg. -2014. -№ 24 (1). -Р. 42–55.

Библиографические ссылки

Galimov O.V., Khanov V.O., Sagitdinov R.R. Surgical treatment of cholecystitis in patients suffering from obesity / O.V. Galimov, // Surgeon. - 2018. - No. 9-10. - P. 13-17.

Dedov I.I., Melnichenko G.A., Shestakova M.V. et al. National clinical guidelines for the treatment of morbid obesity in adults. 3rd revision (Treatment of morbid obesity in adults). Obesity and metabolism. - 2018. - T. 15. - P. 53-70.

Kornyushin O.V., Toropova Ya.G., Neimark A.E. et al. Mechanisms of influence of bariatric surgeries on the course of non-alcoholic fatty liver disease. Experimental and Clinical Gastroenterology. 2017. 146 (10): 61-73.

Neimark M.I., Pantyushin A.A., Zhilin S.V. Effect of mini-gastrosurgery for morbid obesity on carbohydrate metabolism parameters. Medical alphabet. 2022; (30): 37–40.

Uspensky Yu.P., Petrenko Yu.V., Gulunov Z.Kh. et al. Metabolic syndrome. Study guide. – St. Petersburg, 2017. – p 60.

Fried M. Et al. Interdisciplinary European guidelines on metabolic and bariatric surgery. International Federation for the Surgery of Obesity and Metabolic Disorders - European Chapter (IFSO-EC) and European Association for the Study of Obesity (EASO) //Obes Surg. -2014. -№ 24 (1). -Р. 42–55.