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CHARACTERISTICS OF THE CLINICAL COURSE OF CHRONIC
CHOLECYSTITIS BASED ON COMORBIDITY IN THE GERONT-
SUPERGERONT POPULATION OF THE OASIS, DIRECTIONS FOR
PREVENTION
Botirov J.A.
Madazimov M.M.
Mamasoliev N.S.
Nishonova N.A.
Andijan State Medical Institute, Uzbekistan
https://doi.org/10.5281/zenodo.12741975
Relevance and necessity of the topic.
Scientific observations devoted to
solving cholecystitis and its therapeutic and surgical problems were carried out
in the population of different ages [1; 2; 3; 4].
Conservative treatment of cholecystitis is ineffective in up to 80%, and as
a result, surgery is performed against the background of complications. For this
reason, mortality in geront clients exceeds 40-50% [5]. Development and
improvement of geronto-cholecystitis screening methods, algorithms and
programs for early detection and prevention, taking into account existing
comorbid diseases and characteristics of cholecystitis, is considered an urgent
issue and necessity.
The aim of the research
is to study and determine the epidemiological,
clinical and preventive characteristics of cholecystitis in the young, middle-aged,
geront and supergeront populations of different regions of Uzbekistan.
Materials and research methods.
This study is considered a
simultaneous epidemiological investigation and it is based on the analysis of the
results obtained in a population of 2682 people. Residents of 6 regions of the
country - Andijan, Namangan, Fergana, Jizzakh, Syrdarya and Kashkadarya -
were involved in the study. Based on the tasks set in the work, 6 simultaneous
epidemiological studies were organized and carried out in the valley and oasis
regions of Uzbekistan.
A detailed description of the organization and conduct of the
epidemiological study was provided: the screening group was formed,
questionnaires were prepared, and the screening group was introduced to the
necessary equipment for the study. A procedure for working with the population
was created and a procedure for checking the population was developed.
Results and Discussions.
The features of the clinical course of chronic
cholecystitis in the geront and supergeront population in the oasis region were
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studied on the basis of comorbidity (11 different) and the priority objects of
prevention were determined.
Comorbidity of chronic cholecystitis was not noted in the supergeront
population of the oasis (due to the absence of a supergeront population).
Based on various comorbidities, chronic cholecystitis, cholecystitis
without stones and cholecystitis with stones were recorded in the following
distribution frequencies in accordance with regional specificity: 1) in
steatohepatitis comorbidity - per 9.5%, 7.1% and 2.4%; 2) chronic viral
comorbidity - 6.7%, 3.4% and 3.4%; 3) in viral liver cirrhosis comorbidity - per
0.00% and 0.00%; 4) in comorbidity of acute ischemic heart disease - per 7.1%,
5.9% and 1.2%; 5) in comorbidity of chronic ischemic heart disease - per 7.0%,
4.9% and 2.1%; 6) in glomerular comorbidity - from 20.8%, 18.3% and 2.5%; 7)
in gastroenterological comorbidity - per 10.6%, 7.1% and 3.5%; 8) when
neurocirculatory asthenia is a comorbidity of chronic cholecystitis - per 5.6%,
2.8% and 2.8%; 9) in comorbidity of joint diseases - per 7.1%, 5.3% and 1.9%;
10) in comorbidity of respiratory diseases - per 3.6%, 3.6% and 0.0%; 11) on the
basis of comorbidity with anemia - per 11.7%, 8.9% and 2.8%; 12) on the basis
of total comorbidity (n=1613/0) – per 9.0%, 6.6% and 2.4%.
Anemic comorbidity (risk 11.7%), glomerular comorbidity (risk 20.8%)
and gastroenterological comorbidity (risk level - 10.6%) are confirmed as a
leading role in increasing the risk of clinical course of chronic cholecystitis in the
geront population under Oasis conditions.
Conclusion
. In general, it was confirmed that the risk of chronic cholecystitis
(severe type, complicated form) increases by at least 9.0% on the basis of
comorbidity in the population of gerontological age of the Oasis.
References:
1.
Arthur J.D.R., Edwards P.R., Chagla L.S. Management of galistone disease in
the elderly //Annals of the Royal College Surgeons of England. –2003; 85(2):91-
94.
2.
Mora – Guzman I., Di Martino M., Bonito A.C. et al. Conservative
management of gallstone disease in the elderly population: outcomes and
recurrence //Scandinavian Journal of Surgery. – 2020; 109(3): 205-208.
3.
Sandblom G., Videhult P., Crona Guterstam V. Et al. Mortality atter a
cholecystectomy: population – based study //HPB. – 2015; 17(3): 240-241.
4.
Zhumatayev D.T., BaimaKhanov A.N., AbdyKadyrov M.K. et al.
Simultancous surgical treatment tactics of acute destructive cholecystitis
combined with choledochlithiasis: A case report. int J Surg Case Rep. – 2020; 70:
231-232.
CURRENT APPROACHES AND NEW RESEARCH IN
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5.
Tsimmerman Y.S. Gastroenterology. Manual. M.: GEOTAR – Media. – 2012:
20-31.
