Республиканская научно
-
практическая конференция
с международным участием
«Современные аспекты развития фундаментальных
наук и вопросы их преподавания»
15
DIABETIC NEPHROPATHY
N. Bahshaliyeva, R. Sholan
Hospital of the Military Medical Directorate of the State Security Service
N. Mustafayeva, T. Gasımova
Azerbaijan Medical University, Department of Human Anatomy and
Medical Terminology
A. İbishova
Azerbaijan Medical University, Department of Pathological Anatomy,
Baku, Azerbaijan Republic
Key words:
dialysis, glomerulopathies, deposit.
Purpose of the research
Among the clinical complications of SD patients, the frequency of kidney
damage has been determined to increase by 2-4 times compared to other
pathologies. 18-20% of people over 65 years of age have diabetic glomerulopathy.
The share of CKD in the structure of kidney pathologies varies regionally, as it
accounts for 20-50% of dialysis patients in European countries, 45.6% in the United
States, 36.0% in Canada, and 34.2% in Germany, 41.0% in Japan, 21.3% in Turkey,
and 54.7% in Malaysia.
Materials and methods
Diabetic patients are 12 times more likely to receive dialysis in the United
States than those without diabetes. In Spain, 21% of CKD patients receive dialysis
each year. In people with diabetes, the death rate from nephropathy is 12-15 times
higher than that of other pathologies. It is known that damage to microvessels,
arteries, and renal tubules during CKD can lead to renal functional disorders and
glomerulopathies (GP).
In general, CP is a group of diseases that develop as a result of immune
complex damage of renal glomeruli, metabolic and functional disorders, diabetes,
and renal amyloidosis. According to its etiology, CP is divided into 2 main groups:
primary and secondary.
Results of the research
Primary CP is mainly caused by systemic damage to the kidneys as a result of
glomerular dysfunction, divided into non-inflammatory (glomerulonephritis) and
inflammatory groups. Non-inflammatory glomerulopathies include lipoid nephrosis
(glomerular membrane damage), local segmental glomerular sclerosis, and benign
familial hematurias (thin basement membrane disease), etc. is attributed. Acute
postinfectious (diffuse proliferative) glomerulonephritis, mesangiocapillary
(membrane proliferative) and crescentic aneuritis (extracapillary proliferative
glomerulonephritis
–
with antibodies against the glomerular basement membrane)
belong to the form of inflammation (glomerulonephritis). Mesangiocapillary
glomerulonephritis itself has 3 main types: subendothelial CP, thick deposit disease,
DQ with subendothelial deposit.
