PATHOGENETIC ASPECTS OF COVID-19 INDUCED PULMONARY FIBROSIS

This article details the pathogenetic aspects of Covid-19 and post-covid-19 lung complications. The mechanisms of viral damage, the cellular level of the host response, as well as the inflammatory and fibrotic responses to Covid-19 arc examined in detail, all the results described show that adequate individually tailored ventilation support for damaged or initially "hard" lungs can reduce the severity of stress-induced release of fibroblast transforming factor beta and to reduce the activity of СРВ-induced activation of profibrotic signals.