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COMPARATIVE FREQUENCY OF PREVALENCE OF VARIOUS FORMS
OF CAPITALA HYPOSPADIAS IN CHILDREN OF ANDIZHAN
Mamasaliev N.S.
Nurmatov E.Kh.
Alimov M.M.
Mamasaliev Z.N.
Qalandarov D.M.
Andijan State Medical Institute, Uzbekistan
https://doi.org/10.5281/zenodo.15130979
Relevance.
Hypospadias as a disease was first described by Galen.
However, hypospadias remains the most important medical and medical - social
problem today throughout the world.
The medical and social significance of hypospadias is due to its high
prevalence, the tendency to a constant increase in the number of patients -
children, high disability due to complications and great economic damage.
In recent years, special attention has been paid to the issues of
epidemiology and prevention of hypospadias. This is due to the fact that despite
the large number of proposed methods of surgical correction, the treatment of
hypospadias still remains one of the most difficult problems in pediatric urology
due to the high percentage of complications.
Treatment of hypospadias is not only a complex, but also not fully resolved
problem. Therefore, the frequency of births of children with various forms of
hypospadias and the high percentage of postoperative complications, which,
according to modern researchers, reach 50%, continues to increase.
In this regard, the search for and study of safe and highly effective screening
(epidemiological innovative approaches) methods for early pre-nosological
prevention and treatment of hypospadias is a pressing problem for medical
science and practical healthcare.
The aim of the study:
to study the prevalence, improve the effectiveness of
prevention and surgical treatment of hypospadias based on our own innovative
developments in children of the Fergana Valley.
The object of the study
was 914 children with hypospadias from the
Fergana Valley (202 in the Andijan region, 467 in the Namangan region and 245
in the Fergana region) aged 0–18 years.
The subjects of the study
were venous and capillary blood, urine, analysis
of subjective and objective data, assessment of risk factors, materials, digital
rectal examination of the prostate gland, data from drug therapy and surgical
treatment, as well as endoscopic and urodynamic equipment.
DEVELOPMENT OF PEDAGOGICAL TECHNOLOGIES IN
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Research methods.
To achieve the goal of the dissertation and fulfill the
set
tasks,
subjective,
physical,
survey,
clinical,
biochemical,
pharmacoepidemiological, instrumental, special (digital rectal, echographic,
transrectal ultrasound, uroflowmetric, urethrocystoscopic, surgical) and
statistical methods were used.
Results of the study:
we studied the comparative aspect of the
epidemiological features of the detection of capitate hypospadias (CHH) and its
individual clinical forms of OHS, DHS and SSHS in children of the Andijan region
of the Fergana Valley. The following levels of prevalence of CHH (n = 113) were
established depending on the age of the examined children: 3.54% at 0-1 years,
69.03% at 2-4 years, 23.01% at 5-9 years, 2.65% at 10-14 years and 1.77% at
15-18 years. The frequency of detection in connection with age differs by 68.3%,
its highest levels occur in the age groups of 2-4 years and 5-9 years [Хi2 15.507;
Df = 8; P < 0.05]. The prevalence rate of OGS in individual age groups of children
was: 0.00% in 0–1 years, 2.56% in 2–4 years, 3.85% in 5–9 years, 0.00% in 10–
14 years, 0.00% in 15–18 years, and 2.65% in 0–18 years. High prevalence was
noted among children aged 5–9 years. Depending on the age of the examined
children of Andijan, the frequency of detection of DGS (n = 99) and SSGS (n = 11)
were established at the following levels: at 0-1 years 75.0% and 25.00% (P <
0.01), at 2-4 years 91.03% and 6.41% (P < 0.001), at 5-9 years 64.62% and
11.54% (P < 0.001), at 10-14 years 66.67% and 33.33% (P < 0.01), at 15-18
years 50.00% and 50.00%, at 0-18 years 87.61% and 9.73 (P < 0.001),
respectively. Relatively high prevalence rates of DGS were found in the age
groups of children 2–4 years, 5–9 years, and 0–1 years, and SGS – in 15–18
years, 10–14 years, and 0–1 years
.
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