513
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
PROSPECTS FOR THE DEVELOPMENT OF PHYTOPREPARATIONS BASED ON
STELLARIA MEDIA
(L.) VILL.
Seitova Zh.D.
Ashirov M.Z.
Zhakipbekov K.S.
Kazakh National Medical University named after S.D. Asfendiyarov, Almaty,
Republic of Kazakhstan
e-mail: seitova.zh@kaznmu.kz, tel. +77014700048
https://doi.org/10.5281/zenodo.17343674
Relevance.
Chickweed (
Stellaria media
(L.) Vill.) is a widely distributed medicinal plant
containing flavonoids (apigenin and kaempferol glycosides), phenolic acids, and saponins, exhibiting
antioxidant, anti-inflammatory, and antimicrobial activity. The plant is used in traditional medicine
for inflammatory diseases and metabolic disorders, which confirms the prospects for the development
of phytopreparations.
Aim of the study.
To summarize current data on the phytochemical composition and
pharmacological properties of
S. media
and to assess the possibilities of its application in
pharmaceutical practice.
Materials and methods.
A review of publications in
PubMed
,
Scopus
, and
Web of Science
databases for 2000-2025 was carried out; data on chemical composition, pharmacological effects, and
extraction methods were analyzed.
Results.
More than 12 flavonoids, mainly apigenin C-glycosides, as well as saponins and
phenolic acids, have been identified in
S. media
extracts, which determine its antioxidant and anti-
inflammatory potential. The extracts demonstrate pronounced radical scavenging activity, moderate
inhibition of lipoxygenase and hyaluronidase, accelerate wound healing in cell models, and show
antimicrobial activity against
S. aureus
and
E. coli
. Several studies have shown antiviral activity of
aqueous and alcoholic fractions against HBV. Anti-obesity effects have also been reported in
experimental animal studies.
Conclusion.
The div of evidence indicates the prospects for developing phytopreparations
based on chickweed, primarily topical formulations for the treatment of inflammatory and infectious
skin diseases. Further standardization by flavonoid content and preclinical and clinical studies on
safety and efficacy are required.
