INTERNATIONAL JOURNAL OF ARTIFICIAL INTELLIGENCE
ISSN: 2692-5206, Impact Factor: 12,23
American Academic publishers, volume 05, issue 04,2025
Journal:
https://www.academicpublishers.org/journals/index.php/ijai
page 1499
COBALT. ITS IMPORTANCE IN THE BODY. WHICH COMPOUNDS ARE USED
IN MEDICINE
Barotova Nodira
Student of the Faculty of Fundamental Medicine, Group 101,
Samarkand State Medical University
Scientific advisor:
Karjavov Abdikhakim Rakhmonovich
Samarkand State Medical University, Samarkand, Uzbekistan
Email:
arkarjavov@gmail.com
Email:
zoyirovnanodira006@gmail.com
Introduction.
Cobalt is present in the div as a trace element and has great biological importance. This
element plays a particularly vital role in human health, as it is necessary for a number of vital
processes. Cobalt is mainly found in vitamin B12, which has a special significance and plays
a major role in the prevention of various medical conditions. This thesis discusses the role of
cobalt in the div, its chemical compounds, and its applications in medicine.
Keywords:
cobalt, importance in the div, vitamin B12, use in medicine, trace elements,
chemical compounds.
Literature Review.
Various scientific studies and literature are available on the importance of cobalt in the div
and its use in medicine. These sources provide important information on the biological role of
cobalt, diseases associated with its deficiency, and its use in various medical fields, especially
oncology and diagnostics.
1. The role of cobalt in the div and its importance in vitamin B12
. One of the main
functions of cobalt in the div is its presence in the composition of vitamin B12. Vitamin
B12, or cobalamin, is essential for the formation of red blood cells, and its deficiency can
lead to pernicious anemia. The metabolism of vitamin B12 is directly related to the proper
amount of cobalt. In addition, vitamin B12 ensures the normal functioning of the nervous
system, and its deficiency can lead to neuropathic symptoms (such as headaches, numbness
in hands and feet, impaired motor functions) (Smith et al., 2005).
2. Cobalt isotopes and their use in medicine
. The use of cobalt in medicine is mainly
carried out through its radioactive isotope — cobalt-60 (Co-60). Due to its emission of high-
energy gamma rays, cobalt-60 is effectively used in radiotherapy. It is used as an important
tool in the treatment of large tumors, including cancer. The therapeutic effect of cobalt-60 has
been utilized in medicine for many years, and many scientific works describe its distribution
and effectiveness (Mettler, 2003).
INTERNATIONAL JOURNAL OF ARTIFICIAL INTELLIGENCE
ISSN: 2692-5206, Impact Factor: 12,23
American Academic publishers, volume 05, issue 04,2025
Journal:
https://www.academicpublishers.org/journals/index.php/ijai
page 1500
3. Cobalt and toxicology
. Excessive intake of cobalt into the div can have toxic effects. A
high level of cobalt, especially from compounds such as cobalt chloride or cobalt sulfide, can
lead to health issues. Prolonged excessive intake of cobalt may result in cobalt toxicity,
which can impair the functions of the heart, kidneys, and lungs. Many scientific works
present data on the toxic effects of cobalt (Goyer, 1999).
4. Other cobalt compounds and their use in medicine.
Other chemical compounds of
cobalt, such as cobalt oxides and cobalt-nickel, are used in industrial fields, but in medicine,
these compounds are more often used in diagnostic methods or equipment. Cobalt
compounds are also used in prosthetic devices and dental materials due to their corrosion
resistance and biocompatibility (Gier et al., 2014).
5. Biologically active compounds of cobalt and new medical prospects
. Recent scientific
studies have been exploring the creation of new biologically active compounds containing
cobalt. Such new cobalt-containing compounds, for example, cobalt-organic compounds, can
serve as biologically active substances. These studies may open up new medical applications
for cobalt, especially in the development of medicines and new treatment approaches (Li et
al., 2018).
The information provided in the literature about the importance of cobalt in the div and its
use in medicine further expands our understanding of its essential role and applications in
various medical fields. Cobalt, mainly as a component of vitamin B12, supports vital bodily
functions. Moreover, its radioactive isotope — cobalt-60 — has significant value in
radiotherapy for cancer treatment. Due to its toxic effects, cobalt must be used with caution,
and the development of new biologically active compounds may further expand its medical
potential.
Conclusion.
In conclusion, cobalt is one of the essential trace elements in the div, and its sufficient
presence is necessary for various vital processes. The importance of cobalt in vitamin B12
shows that a deficiency of this element can lead to serious health problems. The chemical
compounds of cobalt are effectively used in medicine, especially in oncology and
radiotherapy. At the same time, due to the toxic effects of cobalt, it must be used carefully. In
the future, the wider use of cobalt in medicine and further research into its biological
importance will be necessary.
References:
1.
Mettler, F.A.(2003). Medical applications of radioisotopes: Use of cobalt-60 in
radiotherapy. Journal of Radiology and Oncology, 12(1), 35-47 - betlar
1. 2.Li, J.Zhang, L & Wang, Y.(2018).New biological activity of cobalt-containing
compounds. International Journal of Biological Sciences,14(7),773-784 - betlar
2. 3.Gier,R.J.Mahan, J.E.&Williams, J. R.(2014).Biocompatibility of cobalt-based alloys in
medical applications. Journal of Materials Science: Materials in Medicine, 25(8), 1863-
1870- yil
INTERNATIONAL JOURNAL OF ARTIFICIAL INTELLIGENCE
ISSN: 2692-5206, Impact Factor: 12,23
American Academic publishers, volume 05, issue 04,2025
Journal:
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page 1501
3. 4.Miki,M.,&Shimizu,T.(2010).Cobalt-based medical materials: From development to
applications. Biomaterials, 31(36), 9519-9527 - betlar
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