International Journal of Medical Science and Public Health Research
12
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TYPE
Original Research
PAGE NO.
12-62
DOI
10.37547/ijmsphr/Volume06Issue05-03
OPEN ACCESS
SUBMITED
17 March 2025
ACCEPTED
22 April 2025
PUBLISHED
03 May 2025
VOLUME
Vol.06 Issue 05 2025
CITATION
Akeem Ayobami Adewole, Kennedy Oberhiri Obohwemu, Iyevhobu
Oshiokhayamhe Kenneth, Joyce Eberechukwu Idomeh, Sandra
Chinyeaka Nwokocha, Rupali Chauhan, Shubham Sharma, Divya
Motupalli, Mary Akadiri, Funke Abolade Adumashi, Samuel Oluwatosin
Adejuyitan, Oluwadamilola R. Tayo, & Bartholomew Ituma Aleke.
(2025). Awareness, Treatment and Control of Hypertension in Nigeria:
A Systematic Review. International Journal of Medical Science and
Public Health Research, 6(05), 12
–
62.
https://doi.org/10.37547/ijmsphr/Volume06Issue05-03.
COPYRIGHT
© 2025 Original content from this work may be used under the terms
of the creative commons attributes 4.0 License.
Awareness, Treatment and
Control of Hypertension in
Nigeria: A Systematic
Review
Akeem Ayobami Adewole, MPH
Senior Health Support Trainer, Suomen Avustajapalvelut, Helsinki,
Finland
Kennedy Oberhiri Obohwemu, PhD
Faculty of Health, Wellbeing & Social Care, Oxford Brookes
University, GBS, Birmingham Campus, United Kingdom; and PENKUP
Research Institute, Birmingham, United Kingdom
Iyevhobu Oshiokhayamhe Kenneth, MPH
Department of Medical Microbiology, Faculty of Medical Laboratory
Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria
Joyce Eberechukwu Idomeh, PhD
Department of Social Works (DSW), College of Education, Psychology
and Social Work, Flinders University, Bedford Park Campus, Sturt
Road, Bedford Park 5042, South Australia; and PENKUP Research
Institute, Birmingham, United Kingdom
Sandra Chinyeaka Nwokocha, PhD
Faculty of Business & Tourism Management, Canterbury Christ
Church University, GBS Partnership, Birmingham, United Kingdom;
and PENKUP Research Institute, Birmingham, United Kingdom
Rupali Chauhan, MPH
Faculty of Health, Wellbeing & Social Care, Oxford Brookes
University, GBS Partnership, Manchester, United Kingdom
Shubham Sharma, MDS
Independent Researcher, Manchester, United Kingdom
Divya Motupalli, MPHGH
Faculty of Health, Wellbeing & Social Care, Oxford Brookes
University, GBS Partnership, Manchester, United Kingdom
Mary Akadiri, MSc
Faculty of Health, Wellbeing & Social Care, Oxford Brookes
University, GBS Partnership, Birmingham, United Kingdom; and
PENKUP Research Institute, Birmingham, United Kingdom
Funke Abolade Adumashi, MSc
Faculty of Health, Wellbeing & Social Care, Pearson, GBS Partnership,
Manchester, United Kingdom; and PENKUP Research Institute,
Birmingham, United Kingdom
Samuel Oluwatosin Adejuyitan, MSc
Doctoral Researcher, School of Business and Creative Industries,
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University of the West of Scotland, United Kingdom; and PENKUP
Research Institute, Birmingham, United Kingdom
Oluwadamilola R. Tayo, MPH
Faculty of Health, Wellbeing & Social Care, Oxford Brookes
University, GBS Partnership, Leeds, United Kingdom
Bartholomew Ituma Aleke, PhD
Faculty of Health, Wellbeing & Social Care, Oxford Brookes
University, GBS Partnership, Leeds, United Kingdom
Corresponding Author: Kennedy Oberhiri Obohwemu, PhD
Faculty of Health, Wellbeing & Social Care, Oxford Brookes
University, GBS, Birmingham Campus, United Kingdom; and
PENKUP Research Institute, Birmingham, United Kingdom
Abstract:
Background:
Inadequate hypertension diagnosis and
management in Nigeria is a key contributor to
cardiovascular morbidity and death. To direct
appropriate preventive actions in Nigeria, a better
knowledge of the existing burden of hypertension is
required, including awareness, treatment, and
management. To evaluate the trends of hypertension
throughout the nation's various states, a systematic
review was done.
Methods:
A thorough literature search was conducted using
PRISMA guidelines to find empirical research on
hypertension and obesity in adult Nigerians. In order to
find original publications about the recognition,
management, and control of hypertension in Nigeria
published between 2002 and 2022, PubMed, Scopus,
and CINAHL were used as the major databases. Africa,
Nigeria, awareness, therapy, control, and hypertension
were the main search phrases. To provide for more
research, the bibliographies mentioned in the
indicated papers were investigated. The articles' full
texts were retrieved from a variety of online resources.
This data was gathered using a data extraction form.
Results:
The requirements for inclusion were satisfied by 48
studies from each of the nation's six geopolitical
regions. Regional differences in awareness, treatment,
and control were significant. The awareness of rural
people was lower than that of urban people. The
South-South region has the greatest prevalence of
hypertension. The lowest rates of hypertension
management were seen in the South-West. Even
among respondents who were aware of their condition
and those who were receiving treatment, there was
typically inadequate control of hypertension across the
nation. There were no estimates specific for either
gender.
Conclusion:
Hypertension is only marginally understood, treated,
and controlled. For hypertension patients in Nigeria to
experience improved outcomes, tailored studies are
needed to identify the precise causes of these low
levels.
Keywords:
Hypertension, Awareness, Treatment,
Control, Risk Factors, Nigeria, Africa
Introduction:
Cardiovascular diseases (CVDs) have
emerged as the leading global cause of death, primarily
driven by modifiable risk factors such as tobacco use,
alcohol
consumption,
hypertension
(HTN),
dyslipidaemia, obesity, poor diet, and physical inactivity
(Glovaci et al., 2019; WHO, 2021). Once considered a
problem of high-income countries, CVDs now represent
a major public health concern
in sub-Saharan Africa (SSA), where the dual burden of
infectious and noncommunicable diseases continues to
strain fragile health systems (Minja et al., 2022;
Wekwete et al., 2022).
Nigeria, the most populous country in Africa,
exemplifies this epidemiological transition. Rising
urbanisation and lifestyle shifts have contributed to an
increasing prevalence of HTN and overweight/obesity,
which are now significant contributors to morbidity and
mortality (Issaka et al., 2018; Choukem et al., 2020).
HTN-related conditions such as heart failure, stroke, and
renal disease have become common, often diagnosed
late or not at all. Recent studies highlight the ongoing
challenges in managing hypertension in Nigeria. For
instance, a 2021 meta-analysis revealed that among
Nigerians with hypertension, only 29% were aware of
their diagnosis, 12% were on treatment, and a mere 3%
achieved control (Ogungbe et al., 2024). In a recent
study, over 45% of sudden cardiac deaths were
attributable to hypertensive cardiovascular disease
(CVD), yet only 10% had a prior diagnosis (Danladi et al.,
2025). Similarly, a tertiary hospital in Nigeria reported a
43% case-fatality rate among hypertensive patients
(Danladi et al., 2025).
The burden is compounded by the co-existence of
undernutrition and rising obesity rates, presenting a
unique challenge for public health systems in SSA
(Sahoo et al., 2015; Ajayi et al., 2016). Moreover, ethnic
minority populations who migrate to high-income
countries often exhibit increased CVD risk, suggesting
that environmental and socioeconomic factors play a
substantial role (Vyas et al., 2024; Hossain et al., 2025).
Globally, hypertension (HTN) is responsible for over 10
million premature deaths and more than 218 million
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disability-adjusted life years (DALYs) annually (WHO,
2023). Projections estimate that by 2025, 1.5 billion
people
—
approximately one-third of the global
population
—
will be hypertensive due to rising life
expectancy and obesity (Boateng & Ampofo, 2023). In
high-income countries, advances in HTN management
have led to a 40% reduction in stroke risk and at least
a 25% reduction in myocardial infarction (Dzau &
Balatbat, 2024), but such progress has not been
mirrored in sub-Saharan Africa (SSA) (Nyame et al.,
2024).
Despite the seriousness of the issue, HTN often goes
undiagnosed and undertreated in SSA due to limited
healthcare access, poor awareness, and resource
constraints (Nyaaba et al., 2020). Many studies are
hospital-based, excluding undiagnosed individuals in
the community and leading to underestimates of the
true burden (Agimas et al., 2024; Swambulu et al.,
2024). National estimates suggest HTN prevalence in
Nigeria is 30.6% in urban and 26.4% in rural areas
(Adeloye et al., 2015), yet few comprehensive reviews
have synthesised this data in recent years.
This study aims to systematically review available
literature on HTN in Nigeria
—
focusing on prevalence,
awareness, treatment, and control
—
to guide public
health policy and inform future interventions.
METHODS
Search Strategy
The Preferred Reporting Items for Systematic Reviews
and Meta-Analyses (PRISMA) statement was adhered
to in this systematic review (Page et al., 2021). To
provide a more thorough and up-to-date assessment
and to identify patterns and trends in knowledge,
treatment, and management of HTN in Nigeria, articles
published in the English language between 2002 and
2022 were taken into consideration.
If studies provided HTN prevalence estimates, they
were considered. Studies on obstetrics, pharmacology,
anthropology, reviews, government publications,
protocols, pre-prints, studies conducted outside of
Nigeria, and research on Nigerians who live outside the
country were all excluded. Studies that used medical
testing as part of the pre-selection process for
employment opportunities were also disqualified. The
results of many investigations involving the same group
of patients were combined, although the references
listed distinct publications outlining the incidence of
HTN. Studies that merely employed self-reporting of a
history of HTN without taking a blood pressure reading
were disqualified. Studies that exclusively looked at HTN
prevalence in men or women were excluded as well. The
search was done in English and focused only on English-
language articles.
To
find
empirical
studies
on
HTN
and
overweight/obesity in adult Nigerians, PubMed, Scopus,
and CINAHL were searched. The African Index Medicus,
African Journal Online, WHO Global Cardiovascular
Infobase, and Google Scholar were also looked up. To
increase the number of studies found, the references of
all pertinent research publications were manually
examined.
Subject headings and free text keywords were
incorporated to increase the search's breadth. A search
for papers with the terms "HTN" or "BP" in the title or
abstract was added to the medical topic headings
(MeSH). The names of all 36 states (including FCT,
Abuja) and the country Nigeria were utilised as
additional key search phrases to find articles that cover
the length and breadth of the African nation. The
numerous keywords connected to the pertinent
Boolean operations are shown in Table 1. The search
technique also includes the use of HTN, high blood
pressure (BP), obesity, overweight, div mass index
(BMI), risk factors, and prevalence as keywords. To
include the most articles, all MeSH terms and keywords
were shortened and exploded.
Table 1: Search Terms
S/N
Subject Headings and Keywords
1.
Africa or sub-Saharan Africa or West/Western Africa or Nigeria
2.
Morbidity or Mortality
3.
Disease Burden or Epidemiology
4.
Hospital Admission*
5.
Case Fatality or Case Fatality Rate*
6.
Risk Factors
7.
2 OR 3 OR 4 OR 5 OR 6
8.
HTN or High BP or Cardiovascular Risk* or Hypertensive Heart Disease or
Cardiometabolic Risk*
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9.
Knowle*ge or Awareness or Attitude* or Behavio*r or Practice* or Treatment or
Control
10.
1 AND 7 AND 8 AND 9
11.
Limit 10 to “2002-2022”
All possibly relevant publications' abstracts were
examined, and complete articles were evaluated.
Records with duplicates were eliminated. Following an
assessment of the titles, articles that were blatantly
unrelated to the topic of interest were deleted. All
possibly pertinent papers' complete texts and abstracts
were examined. If additional items did not meet the
requirements for inclusion, they were deleted.
By dividing the total number of individuals with HTN
(BP 140/90 mmHg and/or usage of antihypertensive
medications) by the total participants in the included
studies, the prevalence of HTN was calculated. By
dividing the total study participants by the HTN
prevalence in the study, the number of individuals with
HTN in each study was calculated.
Data Extraction
The year of publication, study location, study
methodology, participant count, mean age range,
gender distribution, comorbidities, HTN prevalence,
and awareness levels, therapy, or control were all
gathered using a data extraction sheet. These variables
were also retrieved in cases where they were present
and predicted the states of awareness, treatment, and
control. Results from multi-regional research were
broken down wherever it was possible to indicate the
level of awareness, treatment, and control in various
states and areas. When it wasn't possible to separate the
data by state or area, the research was presented as a
whole and the states or regions where it was conducted
were noted.
For their definition of HTN, the majority of studies
employed the threshold of 140/90 mmHg and/or the
usage of antihypertensive medications. In accordance
with current WHO recommendations, a few research still
employed the previous 160/95 mmHg cut-off value.
Quality Assessment
According to prior research, the quality evaluation
standards for studies looking at the prevalence of chronic
illnesses were used (Stanifer et al., 2014; Adeloye et al.,
2017). The representativeness of provided estimates
within the major geopolitical zones and the explicit
explanation of methodologies, procedures, case
ascertainment, and sampling were evaluated for. The
quality of the studies was rated as high (4-5), moderate
(2-3), or low (0-1) (see Table 2).
Table 2: Quality assessment criteria for studies examining prevalence of chronic diseases
Item
Quality criteria
Assessment
Score
Maximum
score
Sampling
Was the sampling
described
and
representative of a
target subnational
population?
Yes
2
2
Not
representative
1
Not described
0
Statistical
analysis
Was the statistical
analysis
appropriate?
Yes
1
1
No
0
Case
ascertainment
Was the procedure
for identification of
cases
clearly
described?
Yes
2
2
Ambiguous
1
Not described
0
Grading
Total (
high (4-5), moderate (2-3), or low quality
(
0-1
))
5
Data Analysis
A narrative strategy was used to analyse the data. The
narrative synthesis found patterns shared by the
different studies, and these themes were investigated to
identify potential factors with significant significance
for Nigeria's attempts to manage HTN.
A meta-analysis of the given data was not possible due
to the heterogeneity of the research designs and the
absence of specified confidence ranges in the majority of
the investigations.
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RESULTS
Search Results
A total of 5,619 articles were found through the searches,
the bulk of which came from the three main databases
(PubMed, Scopus, and CINAHL) (see Table 3).
Table 3: Sources and Number of Studies Retrieved During the Literature Search
S/N
Data Sources
Number of Studies Identified
1.
PubMed
2678
2.
Scopus
1361
3.
CINAHL
1009
4.
WHO Global Cardiovascular Database
276
5.
African Index Medicus (AIM)
123
6.
African Journals Online (AJOL)
82
7.
Google Scholar
54
8.
Google Searches
21
9.
Reference Lists of Relevant Studies
15
3210 papers were checked for indications of a
population-based research on HTN in Nigeria after
duplicates were eliminated. 2023 studies were
disqualified after using the selection criteria. Using the
chosen criteria, 386 full text articles were specifically
examined. Final selections for qualitative synthesis
included 48 studies (see Figure 1).
The vast majority of research were cross-sectional
population-based investigations. A total of 54,215
people were covered by the 48 studies, which were
chosen from across Nigeria's six geographical zones.
South-South was the region with the most studies (17),
followed by South-East and South-West with 10
apiece. The North-East and North-West were each
represented by three studies, while the North-Central
was represented by four. Participants in one nationally
representative research came from various geographic
regions of the nation.
In this study, a variety of populations were covered.
Nationwide, one research was undertaken. Each of the
three types of settings
—
urban, semi-urban, and
rural
—
saw the conduct of 37 research, including 11 in
mixed urban-rural settings. Participants in the
community-based research included in this evaluation
were primarily drawn from market communities and
resided in rural areas. The majority were housewives,
small-time traders, motorcycle riders, artists, local
government employees, and farmers and fishers
(Omuemu et al., 2004; Ofuya, 2007; Adedoyin et al.,
2008; Andy et al., 2012; Asekun-Olarinmoye et al., 2013;
Adebayo et al., 2013; Ezejimofor et al., 2014).
The study's time frame spanned 2003 through 2020. The
majority of the investigations, with the exception of four
(Odili et al., 2008; Amira et al., 2010; Hendriks et al.,
2012; Murthy et al., 2013), were carried out within a
year. 15 of the 48 research were published between
2000 and 2009, 32 between 2010 and 2019, and 1
between 2020 and June 2022. As a result, the annual
rate of output rose gradually from 1.5 in the 2000s to
3.2 in the 2010s before dropping precipitously to 0.1 in
2020
–
2022.
In the research included in this review, the sample sizes
ranged from 75 individuals in a study at a medical school
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Fig. 1. PRISMA Flowchart
in Port Harcourt (Ordinioha, 2013) to 13,504 in a study
conducted at several locations across the nation
(Murthy et al., 2013). The participants' ages ranged
from 15 to 99 years old. Both sexes (male and female)
were represented in every study. More women than
males took part in the majority of the research. The
men were better represented in the community-based
research that focused on farmers, traders, rural
residents, and market communities.
The prevalence of HTN was often greater and more
variable in regional studies (13.2%-55.9%) than it was
in nationally representative samples (46.8-51.6%). The
features of the studies are presented in Appendix 1.
Data Extraction
Appendix 2 summarises the findings of the systematic
review including any factors associated with diagnosis,
treatment, and control where available.
Quality Appraisal
A total of 21 studies received high ratings, while the
remaining 27 received intermediate ratings (Appendix
3).
Data Analysis
1. Hypertension Prevalence
The frequency of HTN varied greatly. Comparing
prevalence rates was challenging because the majority
of them were not age-standardised. The incidence
varied across studies that focused on populations under
40 years old, from 13.8% in a university community in
the Niger Delta area (South-South, Nigeria) to 47% in the
6th battalion army barracks of Ibawa, Abak in Akwa
Ibom (South-South, Nigeria) (Ekanem et al., 2012).
According to research including senior people,
hypertension was more common overall, with a
prevalence of 65% in a rural community in Bayelsa State
(Egbi et al., 2013). There were no estimates for either
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gender.
2. Hypertension Awareness
This review defined awareness as previous knowledge
of a hypertensive state. In rural areas of Cross River
and Akwa Ibom States, awareness levels were lowest
(2.8%). (Andy et al., 2012). The market people in Enugu
has the greatest awareness levels (29.4%). (Ulasi et al.,
2011). Adim, a semi-rural locality in Cross River State,
had awareness levels of 3.1%, while rural villages in
Ilorin had awareness levels of 3.0%. (Hendriks et al.,
2012). According to Omuemu et al. (2004), awareness
levels in Udo, a rural village in Edo State's Ovia South-
West LGA, were 18.55%.
3. Hypertension Treatment Only two studies out of the
48 included in this evaluation assessed this outcome,
demonstrating the paucity of research on treating
hypertension (Omuemu et al., 2004; Hendriks et al.,
2012). In a population-based cross-sectional study in
the remote Edo State village of Udo, 18.5% of
participants were aware of their hypertension
condition, and 77.3% were receiving treatment for it
(Omuemu et al., 2004). Only 2% of participants in rural
settlements in Ilorin were found to be taking anti-
hypertensive drugs, which indicates a poor treatment
rate for HTN (Hendriks et al., 2012).
4. Hypertension Control
In a university town in South-West Nigeria, 14.6% of
those who had HTN had previously received a
diagnosis, but only 4.8% of them had their blood
pressure under control; 6.4% of the responder
population had just received a hypertension diagnosis
(Erhun et al., 2005). In a rural community in Edo State,
of the 77.3% individuals who were receiving
hypertension therapy, 29.4% had appropriate blood
pressure control (Omuemu et al., 2004). Only 3% of
participants in Ilorin's rural areas had blood pressure
readings under 140/90. (Hendriks et al., 2012).
5. Predictive Factors for Hypertension Awareness,
Treatment, and Control
HTN knowledge levels were greater in females,
increased with age, and, notably, reduced with better
educational status in a rural community in Ovia South-
West LGA of Edo State (Omuemu et al., 2004). This
unexpected conclusion may be attributed to the
tendency of people with higher educational levels to
be busier and less able to fit in frequent blood pressure
tests because they are more focused with other things,
such their work. Female sex, hypercholesterolemia,
and hyperuricemia were independently linked to
obesity in a study of healthy individuals in Kaduna
(Wahab et al., 2011). In Ahiazu Mbaisa, Imo State, over
30% of middle-aged individuals frequently drank
alcohol, whereas 23% frequently ate salty foods (Mbah
et al., 2013). These were all linked to risk factors for high
BP along with having a high BMI.
Age, sex, obesity parameters, pulse rate, and localities
in Abia State were the main predictors of high blood
pressure (Ogha et al., 2013). Age, weight, height, waist-
to-hip ratio, BMI, waist-to-hip circumference, and pulse
rate have all been linked to HTN. Except for height, most
of the covariates had a positive correlation with BP.
DISCUSSION
There is a tonne of information available about how
common HTN is in Nigeria. Although prevalence was not
one of the search criteria used in this analysis, various
prevalence levels across areas were reported in certain
publications, many of which support the continued high
incidence. It is crucial to characterise not just the
detection rate but also awareness, treatment, and
control rates, as well as the variables that affect these
rates, in a high prevalence environment like Nigeria. This
would make it possible to develop pertinent,
customised control measures to lessen the effects of
uncontrolled HTN. This detailed study of knowledge,
prevention and control efforts in Nigeria is provided by
this systematic review.
The ageing population, greater urbanisation, poor
lifestyle choices, and the lack of effective national
preventative efforts are likely causes of the significant
and consistent growth in HTN. These findings support
worries that HTN and its associated sequelae may soon
pose the greatest economic and public health hazard in
many African nations, surpassing pandemics of malaria
and other infectious illnesses (Adeloye & Basquill, 2014;
WHO, 2017; Mabuza, 2020).
The frequency of HTN in Nigeria varied significantly by
geopolitical zone, ranging from 25% to 33%, according
to the data. The South-South region has the highest
incidence, at 47%. Adeloye et al. (2021) showed a high
incidence of HTN in the South-East at 33.3%, while
additional research on the geographical pattern of
distribution may be necessary. According to Murthy et
al. (2013), the North-Central has a high incidence of
50.5%. There may be dietary variations in these areas,
especially in the quantity of salt and oil used in cuisine.
Without community strategies to promote healthy
diets, the significant variations in socio-economic
conditions have significant effects on dietary decisions,
especially in urban environments characterised by high
consumption of processed foods (Cappuccio & Miller,
2016; Blüher, 2019; Placzek, 2021). Additionally,
Nigeria's
fluctuating
weather
and
climatic
circumstances have a significant impact on farming and
the types of food crops grown, which may be another
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crucial element in the dietary variations. The findings
showing a greater prevalence of HTN in urban
inhabitants and those who are older are in line with the
results of various other investigations (Twagirumukiza
et al., 2011; Addo et al., 2012; Adeloye & Basquill,
2014; Anchala et al., 2014; Adeloye et al., 2021).
Although prior predictions, with a 5% disparity in 2010
(Adeloye et al., 2015) and 2% in 2020 (Adeloye et al.,
2021), clearly show a diminishing prevalence gap
between men and women, no sex-specific estimates of
HTN prevalence were published in this research. There
has been evidence that women have a somewhat
greater frequency of HTN than males (Murthy et al.,
2013; Adeloye et al., 2021). There may be a connection
between the increased frequency of HTN in women
with the rise in obesity, decline in physical inactivity,
and bad eating habits (Owolabi et al. 2017; Mahumud
et al., 2021; Gaesser & Angadi, 2021). In addition,
women seem to experience severe mental,
psychological, and emotional repercussions from
Nigeria's growing security issues, with frequent panic
episodes likely having a negative impact on many
people's general cardiovascular health (Amusan &
Ejoke, 2017; Kendrick & Isaac, 2021). Additionally, it is
important to keep in mind that women are more likely
to take part in community medical outreach initiatives,
which might result in selection bias and significantly
greater prevalence reported for women (Adeloye et
al., 2015).
Results from this review indicate that knowledge of
hypertension state is often low. The highest degree of
awareness was 29.4%. These rates are lower than
those in other African nations like South Africa and
Zimbabwe, where they are above 30%. (Goverwa et al.,
2014; Adeniyi et al., 2016; Owolabi et al., 2017).
Reducing the burden of cardiovascular disease involves
addressing the comparatively small rates of
awareness, treatment, and management of HTN in
Nigeria. In comparison to North America and Europe,
where temporal assessments have indicated an
increase in awareness from 20 years ago, when levels
were similar to those now reported in Africa, to the
current pace of over 65%, the levels in Africa are far
lower (McAlister et al., 2011). Since it was discovered
that HTN had a significant role in morbidity and death
in these nations, intensive education efforts on HTN
have been credited with the majority of this increased
awareness. While the diverse nature of the research
designs in this evaluation prevented the creation of a
temporal trend, Tanzania, a country that had
numerous consecutive trials, did not experience any
change. It is feasible that more knowledge and thus
increased awareness would result from a comparable
recognition of HTN as the primary cause of mortality.
Our research discovered significantly higher treatment
rates in North Africa than it did anywhere else on the
continent. It's likely that these high standards of care are
influenced by the existence of healthcare coverage in
nations like Tunisia, which encompasses both treatment
and diagnostic services. Universal health care coverage
has improved HTN diagnosis and management in
industrialised countries like the USA, resulting in a
decrease in HTN-related hospitalizations and fatalities
(Joynt et al., 2013). In nations like South Africa that
strive to achieve universal health care, the situation
with HTN may improve. Nationalized health insurance is
still out of reach in various regions of Africa. The
majority of Africans pay for their own medical expenses,
which are somewhat supplemented by a few free
services provided by the government and donor
organisations. These organisations primarily target the
treatment of infectious diseases, with HIV/AIDS control
efforts receiving the largest chunk of this financing (Bala
& Kang'ethe, 2021; Bloom et al., 2022). This necessitates
the development of more creative methods for funding
chronic non-communicable illness care throughout the
continent.
The research taken into account for this evaluation
showed generally poor control rates of HTN. The South-
West has the lowest control levels. Even in states with
high treatment rates, BP control was difficult to achieve.
The definitive determinant of outcomes, control, cannot
be assured by HTN therapy. Numerous research from
diverse locations that were included blamed various
variables for the ineffective BP management. These may
typically be categorised as flaws in the healthcare
system,
patient
noncompliance,
and
doctors'
indifference to treating HTN. Examples of typical health
system flaws impeding the attainment of control include
the absence of anti-hypertensive medicines at medical
facilities and the great distance to the facilities as
documented in several research. On the other hand,
stated competing priorities and a lack of time are
common patient and physician variables that
exacerbate the issue.
Directions for Future Research
Discussions of the developments in awareness, therapy,
and management of HTN were confounded by the cross-
sectional character of the research included in this
review. To investigate the patterns of HTN status,
monitoring or follow-up cohorts must be conducted.
Future research must examine the variables that lead to
the high frequency of HTN in Nigeria. Studies should
provide internationally comparable prevalence rates to
enable comparisons across age groups, sexes, regions,
and time periods worldwide. Such study is necessary for
creating and devising affordable awareness and
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International Journal of Medical Science and Public Health Research
preventive programmes that would assist people in
getting over these obstacles.
Studies should also expand on the advantages of
earlier research, such as the utilization of nationally
representative
and
high
sample
sizes.
The
environmental variables that may influence the
development of predictors of CVDs might be
effectively characterised by longitudinal studies of
immigrants from Nigeria beginning at the time of
relocation to industrialised countries.
Considering that there is presently a dearth of study in
these areas, it is equally important to investigate HTN
knowledge, diagnosis, and management as well as CVD
risk factors.
Strengths and Limitations
The heterogeneity of the studies included in this
review made further analysis challenging. Variations in
population
characteristics,
BP
measurement
procedures, and overall research designs are reflected
in the variability between studies.
This review was challenging due to the scarcity of high-
quality, sizable, and comparable research. Although
the data show that perhaps the prevalence estimates
of HTN and overweight/obesity are high, it was not
able to establish a direct connection between temporal
trends and rising HTN and overweight/obesity
prevalence.
The
analysis,
interpretation
and
comparability of the data were restricted by the lack of
estimates that were sex- and age-specific.
The majority of research studies neglected to examine
the reasons that related to the nation's present HTN
situation, necessitating a thorough investigation of
these issues in order to guide treatments and policy.
Non-random participant selection in several of the
research was another flaw (Ulasi et al., 2011; Ugwaja
et al., 2015).
Only 10 of the 48 studies that were examined in this
review were carried out in the Northern areas, and
information on prevalence by age, sex, and geographic
location was not consistently supplied. Although the
reason for this is unclear, it has been noted in previous
literature (Adeloye et al., 2016; Adeloye et al., 2017;
Adeloye et al., 2021) and may be an indication of the
region's general potential for research.
The study's positives, such as the substantial number
of papers it found, its robust methods, and its supply
of thorough measures of awareness, management,
and control of HTN in Nigeria, more than offset these
drawbacks to a great extent.
CONCLUSION
To lessen the consequences of hypertension (HTN) in
Nigeria, effective and comprehensive national
population prevention initiatives are required.
Occupational health programs should aim to raise
workers' knowledge of health issues generally,
encourage healthy behavior, test for risk factors, and
implement integrated non-communicable disease
(NCD) control. It is important to promote interventions
to lower blood pressure in low-income nations, such as
health education, exercise breaks at work, staff training,
and the establishment of regulations. Health promotion
interventions have improved food habits, physical
activity, and weight reduction (Spring et al., 2021). The
nation's several states should create or update their
coordinated NCD policies and strategies, carry out WHO
STEPS risk factor surveys, and improve primary care for
NCD patients. As a basic preventive measure, there is a
need to boost health promotion in the populace.
Additionally, more public health education is required to
raise hypertension awareness and its consequences.
Communities around the nation need to implement
programs to manage hypertension, and there has to be
an increase in the number of population-based
detection methods for NCDs and cardiovascular disease
(CVD) risk factors. The adoption of healthy lifestyles,
such as weight management, exercise, a sodium-
reduced diet, and moderate alcohol use, should be
emphasized in primary preventive programs as an
efficient way for HTN prevention and control. In order
to reduce HTN affliction and death in young adults,
beginning HTN screening should be implemented
nationwide. The best way to stop an outbreak of HTN is
to increase knowledge, control, and treatment of the
condition while also promoting healthy lifestyle
adoption and maintenance among Nigerians. To follow
developments and shifts in HTN status and to build
national policies to limit HTN outbreaks, Nigeria should
also conduct frequent national health surveys that
include accurate assessment of HTN status.
Nigeria's successful initiatives and programs will
encourage and direct other African nations to
implement these HTN screening and awareness-raising
preventive programs. Research is also required to
determine the causes of regional variations in the HTN
prevalence as well as the reasons why some regions of
the nation lack urban-rural inequalities. Another issue
that has to be addressed is the absence of empirical
information to evaluate national trends. HTN is
becoming more of a problem in Nigeria. The lack of
therapy and awareness is confirmed by this systematic
study. Most importantly, the degree of control is
appalling, indicating that diagnosis and therapy do not
ensure achieving control goals. This circumstance
explains why HTN patients in the nation have poor
International Journal of Medical Science and Public Health Research
21
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International Journal of Medical Science and Public Health Research
results. Patient variables are significant control factors,
even if health system considerations play a significant
role in maintaining this scenario. To enhance patient
outcomes with HTN, research and policy must be
specifically adapted to the gender and geographic
distribution of these characteristics. On a continent
where the focus has up to now been on the
management of severe infections, it is also necessary
to establish customized chronic care models.
CONFLICTS OF INTEREST
The authors declare no conflicts of interest.
FUNDING
This research did not receive any grant from funding
agencies in the public, commercial, or not-for-profit
sectors.
ACKNOWLEDGEMENT
The authors would like to acknowledge the
management and technical staff of PENKUP Research
Institute, Birmingham, United Kingdom for their
excellent assistance and for providing medical
writing/editorial support in accordance with Good
Publication Practice (GPP3) guidelines.
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APPENDIX
Appendix 1: Study Characteristics
S/
N
Author
Study
Year
Location
Geopolitica
l Zone
Study Design
Sample
Size
Study
Setting
1.
Adebayo et al. 2013 Ipetumodu,
Edunabon, and
Moro
Communities
in Ife North,
Osun State
South-West Community-
based
cross-
sectional study
1,000
Rural
2.
Adedoyin et al. 2008 Ile-Ife, Osun
State
South-West Community-
based
cross-
sectional study
2,097
Semi-
urban
3.
Adedoyin et al. 2012 Maiduguri,
Borno State
North-East Population-
based,
cross-
sectional study
1,004
Semi-
urban
4.
Adika et al.
2011
Wilberforce
Island, Bayelsa
State
South-
South
Descriptive
cross-sectional
study
100
Urban
5.
Agaba et al.
2014 Jos,
Plateau
State
North-
Central
Descriptive
cross-sectional
study
883
Urban
6.
Akinbodewa et
al.
2014 Akure
&
Ondo,
Ondo
State, Nigeria
South-West Descriptive
cross-sectional
study
1,183
Mixed
7.
Akpa et al.
2008 Port Harcourt,
Rivers State
South-
South
Descriptive
cross-sectional
study
207
Urban
8.
Akpan et al.
2015 Akwa
Ibom
State
South-
South
Population-
based
cross-
sectional study
1,568
Urban
9.
Amira et al.
2010 Lagos State
South-West Descriptive
cross-sectional
study
1,368
Urban
10. Amole et al.
2008 Ogbomoso,
Oyo State
South-West Descriptive
cross-sectional
study
400
Mixed
11. Andy et al.
2012 Cross River &
Akwa
Ibom
States
South-
South
Population-
based
cross-
sectional study
3,869
Rural
12. Asekun-
Olarinmoye et
al.
2013 Alajue
and
Ibokun, Osun
State
South-West Community-
based,
descriptive
cross-sectional
study
259
Rural
13. Awosan et al.
2013 Sokoto,
Sokoto State
North-West Descriptive,
cross-sectional
study
390
Semi-
urban
International Journal of Medical Science and Public Health Research
31
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International Journal of Medical Science and Public Health Research
14. Bello-Ovosi et
al.
2017 Kawo, Kaduna
State
North-West Population-
based
cross-
sectional study
181
Urban
15. Chukwuonye et
al.
2013 Abia State
South-East Population-
based
cross-
sectional study
2,983
Mixed
16. Egbi et al.
2013 Yenegoa,
Bayelsa State
South-
South
Population-
based
cross-
sectional study
231
Rural
17. Ejim et al.
2006 Enugu, Enugu
State
South-East Population-
based
cross-
sectional study
858
Rural
18. Ekanem et al.
2012 Abak, Akwa
Ibom State
South-
South
Descriptive
cross-sectional
study
442
Semi-
urban
19. Ekpe & Elemi 2016 Adim, Cross
River
South-
South
Population-
based
cross-
sectional study
824
Rural
20. Ekwunife et al. 2009 Nsukka,
Enugu State
South-East Population-
based
cross-
sectional study
756
Mixed
21. Emerole et al.
2007 Owerri,
Imo
State
South-East Descriptive
cross-sectional
study
241
Urban
22. Erhun et al.
2003 Ile-Ife, Osun
State
South-West Descriptive
cross-sectional
study
1,000
Semi-
urban
23. Ezejimofor et
al.
2014 Rivers State
South-
South
Community-
based
cross-
sectional study
2,028
Rural
24. Funke et al.
2013 Jos,
Plateau
State
North-
Central
Descriptive
cross-sectional
study
340
Urban
25. Hendriks et al. 2012 Ilorin, Kwara
State
North-
Central
Population-
based
cross-
sectional study
2,678
Rural
26. Ibekwe et al.
2015 Oghara, Delta
State
South-
South
Descriptive
cross-sectional
study
272
Rural
27. Idris et al.
2020 Lagos, Lagos
State
South-West Community-
based
cross-
sectional study
215
Mixed
28. Ige et al.
2013 Ibadan,
Oyo
State
South-West Descriptive
cross-sectional
study
525
Urban
29. Mbah et al.
2012 Nsukka,
Enugu State
South-East Population-
based
cross-
sectional study
200
Semi-
urban
30. Murthy et al.
2013 Nationwide
Multi-
Zonal
Population-
based
cross-
sectional study
13,504
Mixed
International Journal of Medical Science and Public Health Research
32
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31. Odili et al.
2008 Benin,
Edo
State
South-
South
Retrospective
study
501
Urban
32. Ofuya
2007 Port Harcourt,
Rivers
South-
South
Population-
based
cross-
sectional study
200
Rural
33. Ogah et al.
2012 Umuahia, Abia
State
South-East Population-
based
cross-
sectional study
2,983
Mixed
34. Oghagbon et al. 2007 Ilorin, Kwara
State
North-
Central
Population-
based
cross-
sectional study
281
Urban
35. Oguoma et al.
2015 Kwale, Delta
State
South-
South
Population-
based
cross-
sectional study
417
Mixed
36. Okafor et al.
2014 Enugu, Enugu
State
South-East Population-
based
cross-
sectional study
775
Urban
37. Oladapo et al.
2005 Egbede, Oyo
State
South-West Descriptive
cross-sectional
study
2,000
Rural
38. Olisa
&
Oyelola
2009 Maiduguri
North-East Descriptive
cross-sectional
study
500
Semi-
urban
39. Omorogiuwa et
al.
2008 Ekpoma, Edo
State
South-
South
Descriptive
cross-sectional
study
1,200
Urban
40. Omuemu et al. 2004 Edo State
South-
South
Community-
based
cross-
sectional study
590
Rural
41. Ordinioha
2013 Port Harcourt,
Rivers State
South-
South
Descriptive
cross-sectional
study
75
Urban
42. Ordinioha
&
Brisibe
2013 Omoku, Rivers
State
South-
South
Descriptive
cross-sectional
study
106
Mixed
43. Oyeyemi
&
Adeyemi
2013 Maiduguri,
Borno State
North-East Population-
based
cross-
sectional study
292
Semi-
urban
44. Ugwuja et al.
2015 Igbeagu,
Ebonyi State
South-East Population-
based
cross-
sectional study
267
Rural
45. Ulasi et al.
2010 Enugu, Enugu
State
South-East Population-
based
cross-
sectional study
1,458
Mixed
46. Ulasi et al.
2011
Enugu, Enugu
State
South-East Population-
based
cross-
sectional study
688
Mixed
47. Wahab et al.
2006 Katsina,
Katsina State
North-West Population-
based
cross-
sectional study
300
Urban
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48. Wokoma et al.
2011
Barako, Rivers
State
South-
South
Descriptive
cross-sectional
study
152
Rural
Appendix 2: Data Extraction Table
S
/
N
Author
Study
Year
Study
Objective
Sampling
Strategy
Outcomes
Findings
Comments
1
.
Adebay
o et al.
2013
To
ascertain
the
frequency
of HTN in
individuals
living
in
the South-
West
Nigerian
villages of
Ipetumodu
,
Edunabon,
and Moro.
Using
a
multistage
proportionate
stratified
random sample
approach over a
6-month period,
1000
persons
between
the
ages of 15 and
90
were
recruited.
Prevalence
of HTN
Based on the 140/90
mmHg criteria, the
prevalence of HTN
was 26.4% (Male:
27.3%;
Female:
25.4%). Based on
the 160/95 mmHg
criteria,
the
prevalence of HTN
was 11.8% (Male:
13.5%;
Female:
10.1%).
Significantly
favourable
relationships were
found
between
certain
anthropometric
obesity markers and
blood pressure.
In
all
three
communities, there
was found evidence
of an upward trend
in the prevalence of
HTN. Additionally,
in this cohort, there
was a strong positive
connection between
anthropometric
obesity markers and
BP.
2
.
Adedoyi
n et al.
2008
To find out
how
common
and
prevalent
HTN
is
among the
adult
population
in
the
historic
semi-urban
area of Ile-
Ife, South-
West
Nigeria.
Through
a
multistage
cluster sample
approach, 2097
people over the
age of 20 were
enlisted in the
door-to-door
survey.
Prevalence
of HTN
Using the cut-off
threshold of BP
higher than or equal
to 140/90 mmHg,
22.1% had isolated
systolic HTN and
14.5% had isolated
diastolic HTN. For
blood
pressure
levels more than or
equal to 140/90
mmHg and 160/95
mmHg,
respectively,
a
male-to-female
ratio of 1.7:1 and
1:5 was seen. As
people aged, the
frequency of HTN
The estimates of the
prevalence of HTN
revealed in this
study were greater
than
those
discovered in the
majority of other
investigations
conducted
in
Nigeria,
other
countries in West
Africa, and among
African Americans.
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rose from young to
elderly individuals.
3
.
Adedoyi
n et al.
2012
To find out
how
common
HTN and
obesity are
as
preventabl
e
cardiovasc
ular
risk
factors in a
low-
income
semi-urban
area
of
Northeast
Nigeria.
A
multi-stage
cluster sampling
strategy
was
used to draw in
1004
persons
aged 20 and
older.
Prevalence,
Awareness,
Treatment
and Control
of HTN
40.3, 25.2, 15.4, and
3.8% of people had
pre-HTN,
HTN,
were overweight, or
were obese. The
odds ratios for HTN
were 2.75 (1.25-
6.04)
and
1.62
(0.068-3.82),
respectively, with a
95%
confidence
interval for obese
individuals
compared to normal
weight
and
overweight patients.
The most common
cardiovascular risk
factors
in
the
research population
were PreHTN and
HTN in that order.
Participants
who
were obese had a
relative risk for HTN
that was around
three times higher
than those who were
normal weight and
roughly two times
higher than those
who
were
overweight.
4
.
Adika et
al.
2011
To
measure
non-
academic
staff
members'
understand
ing
of
HTN in a
university
setting in
Nigeria's
Bayelsa
State.
For the study,
100 participants
were recruited.
With a mean age
of 38.4, there
were
53%
females
and
47% men.
Awareness
of
HTN
aetiology,
risk factors
and
prevention
The majority of
employees (73%)
believed excessive
thinking, worry, or
stress to be the
cause
of
heart
disease,
whereas
27% were unable to
understand this fact.
59% of them were
able to identify the
possibility of a
genetic basis for
HTN. Despite the
fact
that
the
majority
of
respondents (72%)
were
able
to
recognise that a
high-salt diet is a
risk factor for HTN,
high-fat
diet,
smoking,
and
alcohol use were
each found to be
responsible by 80,
45, and 43% of
respondents,
respectively,
demonstrating
Employees
who
were not academics
have
inadequate
HTN expertise. The
solution to effective
control
and
treatment of the
health and financial
burden of HTN
remains
strengthening
the
div of information
on the condition.
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insufficient
understanding
of
risk
factors.
A
further 30% were
unaware that HTN
cannot be cured
once in a lifetime,
and 65% did not
realise that HTN
maintenance is for
life. About 80% and
75%
of
the
participants shown
sufficient
knowledge
on
regular drug intake,
BP monitoring, and
measurement,
however 80% did
not understand the
need of weight loss
techniques
for
treating HTN.
5
.
Agaba et
al.
2014
To assess
the
risk
factors for
NCDs and
the
prevalence
of
those
conditions
among
students at
a
university
in
Jos,
Nigeria.
All university
staff
received
invitations to the
University
Health
Clinic
for screenings
using
the
STEPwise
approach
to
NCDs
recommended
by the World
Health
Organization.
Ultimately, 883
people
were
hired.
Awareness
of
risk
factors
of
NCDs.
The most frequent
NCD risk factors
included
dyslipidemia,
inactivity, and poor
fruit and vegetable
intake.
Others
included smoking
cigarettes, drinking
alcohol, and being
obese. The most
prevalent NCD was
HTN, which was
followed
by
diabetes
mellitus
and chronic renal
disease.
The
prevalence of NCDs
showed no gender-
specific differences.
The study found that
NCDs and the risk
factors for them are
quite common in this
group.
Workplace
policies are required
to encourage the
healthier lifestyles
lifestyles.
6
.
Akinbod
ewa et
al.
2014
To
quantify
classic
CKD risk
variables,
pre-HTN
There
were
1,183 adults in
total
(M:F,
0.63:1) in the
study.
Their
biographical
Prevalence,
treatment
and control
of pre-HTN
and HTN.
Pre-HTN
was
prevalent in 32.3%
of the participants,
whereas HTN was
found in 43.4% of
them; 6.2% of the
The population of
Ondo State, Nigeria,
has
a
high
prevalence of pre-
HTN
and
established
CKD
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risk
factors,
and
proteinuria
correlation
s.
information,
past
use
of
cigarette
smoking,
alcohol, herbal
remedies,
NSAID
use,
diabetes,
and
HTN
were
gathered.
patients
reported
having ever had
diabetes; 4.5% had
smoked; 68.3% had
used herbs; and
44.1% had used
NSAIDs.
Haematuria
was
detected in 1.7% of
the
individuals,
whereas 25.9% of
the subjects had
proteinuria. Age and
blood
pressure
significantly
correlated
with
proteinuria.
risk factors. Pre-
HTN
sufferers
should regularly be
tested for CKD and
appropriate referral
done
to
a
nephrologist
for
early treatments.
7
.
Akpa et
al.
2008
To assess
the level of
blood
pressure
manageme
nt among
HTN
patients
being
treated at
the
University
of
Port
Harcourt
teaching
hospital's
specialised
medical
outpatient
clinic
(MOPD).
Patients
who
were
being
treated for HTN
alone
or
with other
conditions at the
UPTH
cardiology
clinic served as
the
study's
participants.
Over the course
of the trial,
consecutive
patients
who
provided
informed
permission were
enlisted as study
participants.
HTN control All
research
participants had an
average
systolic
blood pressure of
14919.33mmHg
and an average
diastolic
blood
pressure
of
93.4813mmHg. 50
individuals in total
(24.2%)
had
managed
blood
pressure that was
less
than
140/90mmHg.
Low numbers of
hypertensive
individuals
were
able to maintain
appropriate
blood
pressure levels. To
maximise
the
benefits
of
antihypertensive
medication, it is
necessary to identify
and address the
obstacles to optimal
blood
pressure
management.
8
.
Akpan et
al.
2015
To
ascertain
the
frequency
of HTN as
well as its
correlates
in
Akwa
Ibom
State,
Nigeria's
rural and
The state's three
senatorial
districts
were
divided into two
urban and two
rural areas at
random.
Prevalence,
Awareness,
Treatment
and Control
of HTN
The mean arterial
BP, systolic blood
pressure,
and
diastolic
blood
pressure were all
greater in rural
people than in urban
people. In contrast
to urban areas, rural
areas had a much
greater frequency of
HTN.
HTN
In Nigeria's rural
villages,
the
frequency of HTN
has
changed
epidemiologically.
These epidemiologic
trends show that the
previously observed
difference in the
frequency of HTN
between urban and
rural
groups
is
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urban
areas.
incidence
was
independently
predicted by age,
BMI,
and
proteinuria.
steadily
disappearing,
necessitating
the
urgent
implementation of
preventative efforts.
9
.
Amira et
al.
2010
In an urban
area
of
Lagos,
Nigeria,
obesity
prevalence
will
be
assessed,
along with
its
association
to HTN.
Every
World
Kidney
Day
from 2006 to
2010, Ikeja, the
administrative
centre of Lagos
state in South-
West
Nigeria,
performed
a
population-
based screening
for CKD risk
factors.
All
volunteers who
were older than
18 years old
were enlisted.
Prevalence,
Awareness,
Treatment
and Control
of HTN
Obesity
and
overweight
were
prevalent in 32.7%
and
22.2%
of
people,
respectively.
The
prevalence
of
obesity was highest
in the age period of
45 to 54 years, and it
was
greater
in
women than in men,
with a rate of 29.5%
in women vs 15.7%
in males. HTN was
prevalent in 33.3%
of the population,
with rates greatest
in people over 65
(58%). The risk of
getting HTN was
2.59 times higher in
obese participants.
39
participants
(3.6%) experienced
proteinuria,
with
4.9%
of
obese
people and 2.4% of
non-obese people
experiencing it.
According to this
study, obesity and
HTN
are
very
common in Lagos.
An important
independent
HTN risk factor is
obesity. As a result,
coordinated efforts
should
be
undertaken to stop
this unhealthy trend
by
encouraging
health education that
places a focus on the
related risk factors
for obesity, such as
eating patterns and
weight increase.
1
0
.
Amole
et al.
2008
To
ascertain
the HTN
and obesity
prevalence
among
people
presenting
to
the
Baptist
Medical
Centre in
Ogbomoso
400 adults who
were at least 18
years old were
sought
out.
Participants
filled
out
a
standardised
questionnaire as
well
as
measures
of
their
blood
pressure
and
weight.
Prevalence
of HTN and
obesity
The prevalence of
obesity
overall,
according to WC,
was 33.8% (men:
8.9%;
women:
53.8%).
Women
spend a lot more
time sitting down
compared to men
(62.4% vs. 50.8%, p
0.05).
In
the
majority
of
instances (85.2%, p
In this scenario, it
was discovered that
women
had
a
disproportionately
high prevalence of
abdominal obesity,
which was linked to
HTN,
sedentary
lifestyles,
and
calorie-dense diets.
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International Journal of Medical Science and Public Health Research
, Nigeria,
as
measured
by
waist
circumfere
nce (WC),
and
to
further
ascertain if
there was
any
relationshi
p between
abdominal
obesity and
HTN.
> 0.05), families of
obese
people
preferred
high-
energy meals. HTN
was
present
in
50.5% of the study
population overall,
with no appreciable
difference between
males and females
(52.0% for men vs.
49.3% for women, p
> 0.05). However,
HTN
prevalence
was 60.0% in the
subgroup of obese
persons.
1
1
.
Andy et
al.
2012
To
evaluate
the impact
of HTN on
public
health in
rural areas
of
Nigeria's
Niger
Delta.
The community
of Okoyong in
the
Odukpani
Local
Government
Area
was
chosen as the
site for the study
of rural Efiks in
Southern Cross
River
State.
Select
fishing
communities in
the
Eastern
Obolo
Local
Government
Area in the
Akwa
Ibom
State region of
the
country
called Obolos
were
researched. At a
few settlements
in the mostly
agricultural
community of
Obot Akara, the
rural
Annangs/Ibibio
s of Akwa Ibom
State
were
researched.
Prevalence
of HTN
The prevalence of
obesity
overall,
according to WC,
was 33.8% (men:
8.9%;
women:
53.8%).
Women
spend a lot more
time sitting down
compared to men
(62.4% vs. 50.8%, p
0.05).
In
the
majority
of
instances (85.2%, p
> 0.05), families of
obese
people
preferred
high-
energy meals. HTN
was
present
in
50.5% of the study
population overall,
with no appreciable
difference between
males and females
(52.0% for men vs.
49.3% for women, p
> 0.05). However,
HTN
prevalence
was 60.0% in the
subgroup of obese
persons.
2.8% of people have
heard
of
HTN
before. 914 people,
Even though obesity
and smoking are
extremely rare in
these two states
(Cross River and
Akwa Ibom), HTN
is
already
a
significant
public
health burden in
rural areas.
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International Journal of Medical Science and Public Health Research
or 23.6% of the
population,
had
HTN; 31.2% of men
and
18.1%
of
women. HTN was
more
common
among 479 (25.5%)
Ibibio/Annangs,
287 (25.6%) Efiks,
and 130 (14.9%)
Obolos than in the
other ethnic groups.
17.2%
of
the
population as a
whole, 17.5% of
men, and 16.9% of
women,
had
preHTN (P=.66).
1
2
.
Asekun-
Olarinm
oye et al.
2013
To find out
how
common
HTN is in
two rural
villages in
Nigeria's
Osun
State.
This population-
based
cross-
sectional
descriptive
study included a
consenting adult
population from
the Alajue and
Obokun
rural
areas
in
southwest
Nigeria who had
shown up for the
screening
procedure.
Prevalence
of HTN
HTN was prevalent
(13.16%). While 11
(4.2%) only had
isolated
diastolic
HTN,
seventeen
(6.6%) only had
isolated
systolic
HTN. 48 (18.5%)
had
ever
used
antihypertensive
medications on a
regular basis, while
236
(91.1%)
engaged in daily
exercise lasting at
least 30 minutes. A
family history of
HTN was reported
by four individuals
(1.6%).
The
respondents'
average div mass
index (BMI) was
23.4 4.9 kg/m2, and
51 (19.6%) had a
BMI between 25
and
29.9;
30
(11.5%) had a BMI
under 30.
In
the
study
population,
HTN
was quite prevalent.
It is strongly advised
to step up primary
preventive measures
to
stop
this
development
in
Nigerian
communities.
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1
3
.
Awosan
et al.
2013
To
evaluate
the eating
habits, way
of
life,
nutritional
condition,
and
prevalence
of
HTN
among
Sokoto's
businesspe
ople.
From November
to
December
2012,
390
dealers chosen
by a multistage
sample process
participated in a
cross-sectional
descriptive
survey.
Participants had
anthropometric
and
blood
pressure
measures,
as
well
as
questionnaire
distribution.
Prevalence
and Control
of HTN
The participants had
a prevalence rate of
unhealthy
dietary
habits: 50.7% ate
their largest meal at
dinner,
49.9%
snacked frequently,
66.7%
consumed
fatty foods, 27.1%
and 33.0% drank
fruit
juice
and
carbonated
beverages at least
three times per
week, and 56.0 and
58.8%
consumed
less
than
three
servings of fruits
and vegetables per
week or none at all.
Additionally, 50.7%
have a sedentary
lifestyle,
5.2%
smoke
cigarettes
now, and 10.8%
drank
alcohol
during the last 30
days. Similar to this,
there
was
a
significant
prevalence of HTN
(29.1%),
obesity
(28.1%),
and
overweight (28.9%)
among the subjects.
According to this
study, there is a
significant
prevalence of bad
eating and lifestyle
choices
among
Sokoto traders, as
well as a high
incidence
of
overweight, obesity,
and
HTN.
The
promotion of good
eating habits and
lifestyle, particularly
among high risk
populations,
is
encouraged through
health education and
other interventions.
1
4
.
Bello-
Ovosi et
al.
2017
To
evaluate
the
prevalence
and
correlation
s of HTN
and
diabetes
mellitus
(DM) in a
city
in
North-
West
Nigeria.
Interviews and
HTN and DM
screenings were
conducted with
adults
who
participated in a
medical
outreach
programme and
were 18 years of
age or older.
Blood pressure,
blood sugar, and
anthropometry
were assessed
using
Prevalence
of HTN and
DM
HTN
and
DM
prevalence
rates
were 55.9% and
23.3%, respectively.
Age over 40 and
being a woman
were related to risk
factors for HTN and
DM, respectively (p
0.05).
Systolic
hypertension
and
age (r = 0.18, p =
0.02),
diastolic
hypertension
and
div mass index (r
= 0.16, p = 0.03),
Due to the high
incidence of HTN
and DM in the study
group, population-
based public health
initiatives aiming at
lowering their risk
factors must be
developed
and
implemented.
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standardised
equipment and
procedures.
blood glucose and
waist circumference
(r = 0.19, p = 0.02)
all showed modest
correlations.
1
5
.
Chukwu
onye et
al.
2013
To look at
the
incidence
of
abdominal
obesity in
Nigeria's
Abia State.
Communities in
the state's three
senatorial zones
were used to
find
research
participants.
The
Stepwise
Approach
to
Surveillance of
Chronic Disease
Risk
Factors
developed
by
the
World
Health
Organization
was
applied.
Additionally,
pertinent
information
such
as
the
anthropometric
measures
and
div mass index
were gathered.
Prevalence
of HTN
Body mass index
data showed that
11.12% of people in
the population were
obese. It was 7.73%
for
males
and
14.37% for women,
respectively. In the
general population,
abdominal obesity
was
prevalent
(21.75%). It was
3.2% for males and
39.2% for women,
respectively.
Nigeria has a high
rate of abdominal
obesity, which has to
be watched since it
raises the risk of
cardiovascular
disease.
1
6
.
Egbi et
al.
2013
To
ascertain
HTN
prevalence
and contri
buting
elements in
the
Ogboloma
communit
y
in
Nigeria's
Bayelsa
State.
All
qualified
respondents wer
e
randomly
selected
from
the group. BP,
anthropometry,
clinical history,
and
sociodemograp
hic information
were recorded.
Prevalence
of HTN, risk
factors for
HTN
HTN was present in
50.4% of cases,
while pre-HTN was
observed in another
41.2%. Age, BMI,
waist-hip
ratio,
hyperglycemia, and
smoking
were
factors connected to
HTN in a univariate
study.
On
multivariate
analysis,
only
smoking and age
remained
significant.
In this remote area,
HTN and Pre-HTN
were very common.
HTN
was
significantly
predicted
by
smoking and age.
Therefore,
rural
areas and smokers
should be the focus
of HTN screenings
and
treatment
programmes.
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1
7
.
Ejim et
al.
2006
To
determine
the
prevalence
of the main
cardiovasc
ular-
related risk
factors in
middle-
aged and
elderly
people in a
rural
communit
y
in
Nigeria
who
are
both male
and female
and
between
the ages of
40 and 70.
Eight hundred
families in total
were chosen at
random, and all
of the adults in
these
households
between
the
ages of 40 and
70 were chosen
for the study.
858 people in
total
volunteered to
participate and
showed up at the
health centres
for the research.
70.4%
of
respondents
responded.
Prevalence
of
major
cardiovascul
ar
risk
factors.
The prevalence of
the
various
cardiovascular risk
factors
was
as
follows among the
858 subjects: HTN
was present in 398
(46.4%),
general
obesity as measured
by BMI was present
in
257
(30%),
abdominal obesity
was present in 266
(31%)
and
dysglycemia
was
present in 38 (4.4%)
and
hypercholesterolem
ia was present in 32
(3.7%). While the
other
conditions
were more common
in women, HTN and
dysglycemia were
more common in
males. Only HTN (p
=
0.17)
and
hypercholesterolem
ia (p = 0.13) did not
show a gender-
related correlation
that was statistically
significant. The age
group
of
participants with the
highest
CVD
prevalence and risk
factors was 65 to 70.
Rural communities
are
seeing
an
increase
in
the
prevalence of CVD
risk factors. HTN
and obesity are more
prevalent in the rural
population than the
other cardiovascular
risk factors that are
frequently
evaluated.
Larger
community health
awareness initiatives
are necessary given
the effects of these
adverse
outcomes
and the general lack
of awareness of
them.
1
8
.
Ekanem
et al.
2012
To
ascertain
high
BP prevale
nce in
a
Nigerian
semi-urban
neighbour
hood.
An
extensive
questionnaire
that
included
anthropometric
measures was
used to gather
the data.
Prevalence
of HTN
As a consequence of
the study, 47.0% of
the population had
elevated
blood
pressure
(>140/90mmHg).
Age, sex, greater
income,
more
family
members
living in the home,
everyday smoking
habits,
regular
alcohol use, and
The necessity for
intervention
and
preventative
measures to stop the
impending
pandemic of HTN in
this
particular
neighborhood and
Nigeria in general
cannot be overstated
because elevated BP
is highly prevalent in
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BMI all revealed an
elevated risk for
high blood pressure
on a univariate
level.
However,
participants
who
slept
for
at
minimum
eight
hours
per
day
demonstrated
a
protective
effect
against elevated BP.
this
semi-urban
neighbourhood.
1
9
.
Ekpe &
Elemi
2016
To
ascertain
the
frequency
of HTN in
the remote
communit
y of Adim
in
the
Nigerian
state
of
Cross
River.
Respondents
were chosen at
random from a
group of 20 to
65-year-olds.
Prevalence
of HTN
Only
5
(3.1%)
individuals
knew
they
had
hypertension. There
were
19.9%
of
people with HTN.
HTN
was
very
common in this
neighbourhood.
Since
many
Nigerians reside in
rural areas and HTN
is
a
major
cardiovascular risk
factor,
decisive
action must be made
to
battle
this
pandemic.
2
0
.
Ekwunif
e et al.
2009
To
evaluate
the
prevalence
of
HTN
and
its
identificati
on,
treatment,
and
manageme
nt in the
city
of
Nsukka in
South-East
Nigeria.
South-East
Prevalence,
Awareness,
Treatment
and Control
of HTN
HTN
prevalence
was 21.1%. Men
were more likely
than women to have
high blood pressure.
Both in males and in
women, systolic and
diastolic
blood
pressure increased
with
age.
In
individuals
with
elevated
blood
pressure, high blood
pressure
was
discovered in 40.3%
of men and 24.7%
of
women,
respectively. Only
5.0%
of
hypertensive males
and
17.5%
of
hypertensive female
s had their blood
pressure
under
The
findings
indicated ineffective
HTN identification,
management,
and
control.
This
emphasises
the
requirement for a
thorough analysis of
HTN as well as other
cardiac
diseases'
prevalence
in
Nigeria.
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control, compared
to 23.7% and 17.5%
of those with high
blood
pressure,
respectively. HTN
prevalence
in
Nigeria and Africa
was comparable to
other research.
2
1
.
Emerole
et al.
2007
To
calculate
the
staff
members'
heart risk
scores at
the Federal
University
of
Technolog
y
in
Owerri,
Imo State,
Nigeria.
At the Federal
University
of
Technology,
Owerri (FUTO),
Imo
State,
Nigeria, a total
of 100 senior
and 141 junior
staff members
were chosen at
random.
Age,
heredity, BMI,
smoking,
exercise,
calculation
of
serum
cholesterol,
systolic blood
pressure,
and
sex were all
recorded using a
questionnaire.
Prevalence
of
cardiovascul
ar
risk
factors
In terms of gender
composition, family
history of CVD,
tobacco
consumption,
or
serum cholesterol,
there
were
no
appreciable
differences between
both the older and
younger employees.
The age distribution
values among senior
personnel
were
much greater.
It is highly advised
to implement health
education
campaigns aimed at
improving lifestyle.
2
2
.
Erhun et
al.
2003
To
ascertain
the
frequency
of HTN in
an Ile-Ife,
Osun
State,
university
communit
y.
Adults over the
age of 21 who
were employed
by the university
at the time of the
study
as
academic
or
non-academic
employees
made up the
study
population. Out
of 5000 people
chosen from all
of
the
university's
faculties
and
service
Prevalence
of HTN
The
respondent
population's overall
crude
prevalence
was 21%. 16% of
them were already
taking medication
for their condition.
The study found no
conclusive evidence
of a link between
coffee intake and
HTN (p>0.05). In
individuals
with
more than three
children,
the
prevalence
was
32%; in subjects
with eye problems,
The population has
to be made more
aware
of
the
condition and some
other
cardiovascular-
related risk factors,
and
self-
measurement
BP
equipment should be
made available or
encouraged to be
owned.
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divisions, 1000
respondents'
agreement was
acquired after
being informed
of the study's
goal.
A
standardised
questionnaire
was utilised to
conduct
an
interview with
them,
gather
basic
demographic
and
socioeconomic
information,
and determine
any history of
HTN.
diabetics,
and
subjects
who
consumed local kola
nuts, it was 18.6%,
1.9%, and 7.4%,
respectively.
2
3
.
Ezejimo
for et al.
2014
To
calculate
the burden
of HTN in
a region of
Nigeria
called the
Niger
Delta that
is heavily
contaminat
ed with gas
and oil.
2,028
locals
(aged 18 to 80)
were enlisted.
Anthropometric
measurements,
lifestyle
and
sociodemograp
hic
variables,
cardiovascular
comorbidities,
and
the
prevalence and
risk of HTN
were
investigated and
compared
between the two
groups.
Prevalence
of HTN
37.4%
of
the
subjects had high
blood pressure. 51
percent
of
participants came
from places with oil
pollution. Only 15%
of
individuals
mentioned having
HTN
in
their
families.
Individuals in the
adjusted model who
lived in oil-polluted
regions had a nearly
5-fold higher risk of
developing
HTN
than
participants
who lived in areas
without pollution.
An elevated risk of
HTN may be linked
to
exposure
to
oil/gas
pollution.
The results require
more investigation
in
longterm
investigations.
2
4
.
Funke et
al.
2013
To
look
into staff
members'
attitudes
and
behaviours
about BP
monitoring
The hospital's
344 staff were
chosen using the
stratified
sampling
approach.
A
systematic
questionnaire
Awareness,
attitudes,
and
practices
towards
HTN
10.3%
of
respondents
had
never had their
weight examined,
and more than half
of
respondents
seldom
monitor
their blood pressure
A change in health
professionals'
attitudes
about
routine
blood
pressure checks will
aid
in
early
diagnosis, effective
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and weight
control, as
well
as
their
patterns of
blood
pressure
and div
mass index
(BMI).
was used to
collect
information
about
educational
background,
profession,
monitoring of
blood pressure
and weight, and
physical
assessment for
both
blood
pressure
and
div
mass
index.
(apart from when
they are sick). Only
29.5%
of
respondents
had
normal
blood
pressure, whereas
36.6%
of
respondents
had
HTN. Only 21% of
respondents thought
they
were
overweight, despite
the fact that a
sizable
majority
(72%) were either
overweight
or
obese. Comparing
obese and non-
obese
patients,
obese people were
more likely to have
hypertension.
Obesity
was
independently
correlated with both
female sex and
physical inactivity.
care, and problems
avoidance.
2
5
.
Hendrik
s et al.
2012
To
evaluate
HTN
prevalence
and
factors that
influence
BP in four
SSA
population
s,
including
urban
Namibia
and
Tanzania
as well as
rural
Nigeria
and Kenya.
By
randomly
assigning
geographic
regions,
stratified
random samples
were created.
Prevalence
of HTN
19.3%
of
rural
Nigerians, 21.4% of
rural
Kenyans,
23.7% of urban
Tanzanians,
and
38.0% of urban
Namibians had age-
standardized
prevalences
of
HTN. According to
those with HTN,
grade 2 or grade 3
HTN
(180/110
mmHg) made up
between
29.2%
(Namibia)
and
43.3% of all cases
(Nigeria). Between
2.6% in Kenya and
17.8% in Namibia,
HTN
was
controlled.
BMI
was
an independent pre
HTN was the most
often noted CVD
risk factor across
both urban and rural
SSA areas, and it
will continue to add
to the region's rising
CVD
burden.
Alarmingly
poor
levels
of
HTN
control. In order to
stop the growing
CVD pandemic, the
health care systems
in SSA must be
strengthened.
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dictor of BP level in
all research groups,
where
the
prevalence
of
obesity (defined as a
BMI 30) ranged
from
6.1%
in
Nigeria to 17.4% in
Tanzania.
2
6
.
Ibekwe
et al.
2015
In order to
assess
if
there is any
correlation
between
these risk
factors and
socio-
demograph
ic
characteris
tics, it was
necessary
to
quantify H
TN
prevalence
and
its
modifiable
factors in a
remote
neighbour
hood
(Oghara,
Delta
State,
Nigeria).
For the study, a
total of 272
respondents
were
chosen
using
cluster
sampling. Data
were gathered
using
a
questionnaire
that
was
administered by
the interviewer.
Prevalence
of HTN and
modifiable
risk factors
HTN
prevalence was
21.0%, although the
prevalence of HTN
risk factors that may
be
changed,
including as obesity,
smoking,
and
alcohol use, was
15.8%, 43.4%, and
18.8%, respectively.
Both HTN and
alcohol
use
(p
0.001) and HTN and
smoking (p 0.001)
showed
a
statistically
significant
correlation. (p <
0.001).
Smoking
and
socio-
demographic
factors were highly
correlated.
The
study
discovered
a
significant
prevalence
of
modifiable
risk
factors for HTN.
This
emphasises
how important it is
to take preventative
steps and encourage
lifestyle
modifications
in
order to stop the
growing NCD and
HTN outbreak.
2
7
.
Idris et
al.
2020
To
ascertain
NCD
prevalence
and predis
posing
factors
among
inhabitants
of Lagos,
Nigeria's
Ijegun-
Isheri
215 participants
who
were
sequentially
recruited as part
of a population
preventive
health
programme
participated in a
population-
based
cross-
sectional survey.
Prevalence
of
NCDs
and
associated
risk factors
Diabetes was 4.6%
more common than
HTN (35.3%), and
dyslipidemia
was
47.1%
more
common. Smoking
prevalence
was
41.3%,
alcohol
intake was 72.5%,
and
physical
activity was 52.9%
among NCD risk
factors. Age 60
Diabetes,
dyslipidemia,
and
HTN are all very
common, as are the
risk factors that go
along with them.
This underlines the
demand
for
more research and
policy
implementation guid
elines to address the
burden of NCDs in
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International Journal of Medical Science and Public Health Research
Osun
neighbour
hood.
years
and
dyslipidaemia were
the independently
significant
predictors of HTN.
Diabetes
was
independently
predicted by age 60
years.
Smoking,
being
employed,
being
physically
active, and being
older than 60 were
all
independent
predictors
of
dyslipidemia.
Nigeria's
metropolitan
neighbourhoods.
These methods must
be
neighborhood-
specific, addressing
the
major
risk
variables in order of
importance.
2
8
.
Ige et al. 2013
To outline
the
prevalence
of a few
NCDs and
the
risk
behaviours
that
go
along with
them in a
Nigerian
university
communit
y.
In
order
to
choose
the
respondents, a
two-stage
sampling
method
was
used.
Four
departments
were chosen at
random from a
list
of
all
departments in
each of the 15
University
faculties in the
first step, which
entailed
the
basic
random
sample
of
departments. In
the second step,
a
systematic
sample of the
listed
employees from
each
chosen
department was
taken;
ten
employees were
therefore chosen
out of the 60
departments
chosen in stage
one. Structured
self-
Prevalence
of NCDs
While 67.4% of
people reported at
least
one
risk
behaviour
(unhealthy
eating
96%,
sedentary
lifestyle
27.4%,
excessive alcohol
use
5.1%,
and
smoking
1.9%),
27.6%
had
previously received
a diagnosis for at
least
one
NCD
(HTN
21.5%,
diabetes
11%,
cancer 2.9%). No
discernible
difference by sex or
age was seen in the
29.9% of people
who
displayed
several
risky
behaviours.
The
incidence of NCDs
was
considerably
greater in those
above the age of 40,
notably for HTN.
Only 7% of people
thought they were at
risk for NCDs. The
perception of risk
for one or more
NCDs was shared
It has been shown
that there is a large
NCD
burden and
unhealthy practices
despite low self-
perceived
risk,
which necessitates
quick action..
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administered
questionnaires
were used to
gather data.
by those who had
parents with NCDs
and those who had
NCDs themselves,
but not by those
who engaged in
multiple
risk
behaviours.
2
9
.
Mbah et
al.
2012
To identify
the
incidence
and
risk
factors for
HTN
among
middle-
aged
people in
Ahiazu
Mbaise
Local
Governme
nt
Area,
Imo State,
Nigeria.
Males
and
females (40–60
years old) were
chosen
at
random from the
two villages to
serve as the
participants.
Prevalence
and
risk
factors
of
HTN
A larger percentage
of
female
participants
(20.0%) than male
subjects
(12.5%)
were reported to
have HTN (32.5%).
25.0%
of
the
participants
were
either overweight or
obese. Less than
half
of
the
respondents
(30.0%)
reported
drinking
alcohol
frequently,
while
23.0%
reported
eating salty foods
frequently.
These
were all identified
as potential causes
of
high
blood
pressure.
Since HTN care
requires
preventative
measures,
the
general population
should be made
aware
of
HTN
predictors, notably a
high
BMI
and
unhealthy food and
lifestyle choices.
3
0
.
Murthy
et al.
2013
To analyse
HTN
prevalence
and
associated
risk
variables,
including
ethnicity,
in a sample
of Nigerian
adults who
were
chosen for
a survey on
visual
impairmen
t
from
A
nationally
representative
sample of 13591
participants
aged 40 years
was
obtained
using a multi-
stage, stratified,
cluster random
sample
with
probability
proportional to
size techniques.
13504 (99.4%)
of them had a
blood pressure
reading.
Prevalence
of HTN and
associated
risk factors.
There were 44.9%
of people who had
HTN. Age, gender,
living in an urban
area, and BMI all
increased
independently
of
one
another
(p
0.001). The ethnic
group
with
the
highest HTN
prevalence
was
the Kanuri.
The high frequency
of HTN in Nigeria is
alarming and shows
that the effects of
connected
poor
health, along with
the
associated
monetary and costs
to
society
and families and the
nation of Nigeria,
are unavoidable.
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International Journal of Medical Science and Public Health Research
across the
country.
3
1
.
Odili et
al.
2008
To assess
how
doctors
adhere to
the
JNC
VII,
WHO/ISH,
and ESH
guidelines
and their
role in the
prevention
and control
of HTN.
Cross-sectional
study
Prevalence,
Treatment
and Control
of HTN
The grade 2 group
had the greatest
prevalence of HTN
(36%). Men were
less affected (40%)
than women (60%)
were.
Diabetes
mellitus was the
most prevalent co-
morbid
condition
(18%). The highest
rates
of
co-
morbidity
were
found in Grades 2
(34%) and 3 (34%).
A
two-drug
combination
was
being taken by 49%
of the participants,
whereas 14% were
receiving
monotherapy. The
anti-hypertensive
medication
most
frequently
administered (31%)
was
a
calcium
channel
blocker,
followed
by
a
diuretic
(30%).
Diuretics were the
most
popular
medication
combination (74%).
In HTN, there was
no proof of div
weight control.
The doctors in this
facility
fairly
followed
the
instructions,
however it doesn't
seem
like
they
suggested lifestyle
changes to their
hypertension
patients.
3
2
.
Ofuya
2007
To
ascertain
the
prevalence
of
HTN
among
adults
in
Nigeria's
Niger
Delta.
While
the
female
participants
were
chosen
from
two
markets in the
hamlet
where
the institution
was located, the
male research
group
was
Prevalence,
Awareness,
Treatment
and Control
of HTN
HTN was more
common in men
than in women
(16% in men and
12% in women).
Male BMI averaged
22.7
kg/m2,
whereas
female
BMI averaged 23.8
kg/m2.
There is a need for
HTN
control
and prevention
measures. Lifestyle
changes and risk
factors, such as a
high BMI, should be
promoted.
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composed
of
commercial
motorcycle
riders
who
frequented the
campus area.
3
3
.
Ogah et
al.
2012
To
ascertain
the
prevalence
and causes
of
high
blood
pressure in
the South-
East
Nigerian
state
of
Abia.
The
research
subjects
were
chosen ad hoc
from one rural
and one urban
local
government
region,
one
senatorial zone,
and each of the
three senatorial
zones (LGA).
Prevalence
and
determinant
s of HTN
The BMI of women
was
substantially
greater than that of
males. Similar to
how
the
waist
circumference was
greater in women,
the
waist-to-hip
ratio
was
only
noticeably higher in
urban women than
in rural women.
Systolic
HTN
affected 31% of
participants overall
(33.5% of males and
30.5% of women).
In the city, there was
a
statistically
different sex gap.
Conversely,
diastolic HTN was
present in 22.5% of
the
population
(25.4% of women
and
23.4%
of
males). The best
predictors of BP
were
age
and
indicators
of
obesity.
Both rural and urban
environments in the
research had a high
frequency of HTN.
Age, sex, indicators
of obesity, and pulse
rate were the main
drivers of blood
pressure
in
the
subjects.
3
4
.
Oghagb
on et al.
2007
To
ascertain
the
prevalence
of
HTN
and related
factors
among
paid Ilorin,
Kwara
State,
A screening was
conducted for
the
identification of
HTN among the
staff members in
collaboration
with the health
services
division of a soft
drink
manufacturing
Prevalence
of HTN and
associated
variables
HTN
affected
27.1%
of
the
population,
with
men
having
a
frequency of 28.4%
and
females
of
22.9%. Females had
considerably greater
mean SBP and DBP.
Age and BMI both
enhanced
the
prevalence of HTN.
In Ilorin, Nigeria,
the prevalence of
HTN is high, with
males being more
likely to have the
disease. In female
employees, the BP
rise
is
more
pronounced. In order
to
reduce
the
morbidities that are
connected
with
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Nigerian
employees.
firm and the
Federal
Secretariat
Complex
in
Ilorin, Nigeria.
These
staff
members
received
thorough
briefings on the
main points of
the show and the
necessity
of
fasting on the
day they were to
be aired.
Age and SBP, DBP,
and
BMI
were
linked. 13.2% of the
population
was
obese, with males
making up 5.3% and
females 7.8%. Both
sexes had a 1.5%
prevalence
of
diabetes mellitus,
which was similar.
obesity, which is on
the rise in Nigerian
society,
early
intervention
is
necessary.
3
5
.
Oguoma
et al.
2015
To
determine
CVD
prevalence
and
predictive
factors as
well
as
how
availability
of
CVD
risk
screening
varies by
poverty
level and
educationa
l
attainment
and
how
this affects
the diagno
sis of the
condition i
n rural and
urban
Nigerian
adults.
Using a two-
stage
cluster
sampling
approach,
researchers
examined
a
culturally ethnic
group of people
who resided in
both rural and
urban areas. All
18-year-old
pupils
from
certain
secondary
schools
were
sampled
for
each
cluster.
Other
participants in
each
cluster
were signed up
through
town
halls, primary
health
care
facilities,
and
school grounds.
Prevalence
of CVD risk
factors
Prediabetes
was
present in 4.9% of
the
population,
diabetes in 5.4%,
HTN in 35.7%, low
HDL in 17.8%,
hypertriglyceridemi
a
in
23.2%,
hypercholesterolem
ia in 38.1%, and
central obesity in
52.2%
of
the
population. Other
CVD risk variables
did not demonstrate
statistically
significant
difference
across
income levels, with
the exception of
total cholesterol and
HDL.
It
was
statistically
significant
that
participants
with
"university
and
postgraduate
degrees" had more
exposure to BP and
sugar
levels
monitoring
than
those from other
educational
backgrounds.
According to this
study,
a
sizable
percentage of adult
Nigerian migrants
from the rural and
urban areas carry
modifiable
CVD
risk factors. While
the prevalence of
CVD risk factors
was not impacted by
economic level, it
did alter access to
CVD risk screening.
At all societal levels,
there is a need for
access to risk factor
diagnosis.
3
6
.
Okafor
et al.
2014
To
estimate
the
Simple random
sampling
was
used to choose
Prevalence,
Awareness,
Treatment
With
a
strong
female
gender
preponderance, the
Among
these
apparently healthy
adult
citizens,
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prevalence
of obesity
and
its
connection
to
blood
pressure
among
urban
adults
living
in
the Enugu
metropolit
an.
four areas of the
city, and then
consenting
people between
the ages of 18
and 70 were
sequentially
recruited.
and Control
of HTN
individuals
had high obesity
prevalence (21.2%).
Age-related burdens
rose,
with
the
middle-aged group
being most affected.
The likelihood of
acquiring obese rose
as age approached
40.
Positive
association, greater
BMI
among
hypertensive
people,
and
significant burden
of raised BP among
obese subjects all
point
to
a
connection between
BP and BMI.
obesity was of a
significant
size.
Increased BP is
related to obesity.
3
7
.
Oladapo
et al.
2005
To
evaluate
and
describe
the
prevalence
of various
cardiovasc
ular-
related risk
factors in a
rural
Yoruba
communit
y in South-
West
Nigeria's
sub-
Saharan
adult
population.
A list created by
field
enumerators
contained
a
systematic
random
sampling
of
houses. Adults
who
were
eligible
were
chosen
as
responders on a
consistent basis.
Per home, no
more than three
respondents
were
chosen.
After receiving
training
in
fundamental
interviewing
techniques and
accepted
procedures for
taking physical
measures,
community
health extension
workers
(CHEW)
Prevalence
of
cardiometab
olic
risk
factors
With blood pressure
over 140/90 mmHg,
20.8%
of
the
responders
had
hypertension.
42.3% of the men
and 36.8% of the
women had blood
pressure
below
130/85
mmHg;
2.5% had diabetes;
1.9%
had
hypertriglycerideae
mia; 43.1% had low
HDL-C; 3.2% were
physically inactive;
and 1.7% smoked
cigarettes. A total of
12.9%
of
the
participants had at
least one CVD risk
factor.
The findings of this
study clearly imply
that cardiometabolic
risk
factors
are
prevalent in this
rural community and
that
the
epidemiological
shift does not only
affect
urban
residents. This is a
call to action for the
treatment of CVD as
well as other NCDs
in the organization
of health services.
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gathered
the
study's data. The
WHO STEPS
survey's
instruments
were used and
modified for the
local conditions.
3
8
.
Olisa &
Oyelola
2009
To
examine
utilisation
of herbal
medication
among
hypertensi
ve patients.
The
study's
recruitment
process
employed
simple random
sampling. The
clinic
record
office
was
contacted
to
recruit
every
other
patient
who
dropped
down their card
in order for the
files
to
be
handed out.
Use
of
herbal
medicine for
HTN control
Age was linked to
more frequent usage
of herbal remedies
(P 0.05). 47.5% of
respondents
reported
co-
administering
herbal medications
with
antihypertensive
drugs, of which
33.33%
utilised
herbs
having
antihypertensive
action. The majority
of
responders
(71.15%)
used
herbal medications
secretly from their
doctors. 21.04% of
respondents
reported
co-
administration
of
herbal medications
and allopathic drugs
to
have
had
clinically obvious
adverse effects. The
reasons stated for
stopping the herbal
medications were
side effects noticed
(3.79%),
improvements
in
clinical
circumstances
(3.03%), reported
ineffectuality of the
herbal
treatment
(1.52%),
and
directions from the
Patients
with
hypertension
frequently
co-
administered herbal
medications together
with
allopathic
medications,
thus
healthcare providers
need to be watchful
and ask patients
about their use of
herbal medications
when gathering their
medical history.
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health practitioner
(21.15%).
3
9
.
Omorog
iuwa et
al.
2008
In order to
compare
the
risk
variables
between
the
younger
employees
and senior
employees
in
the
setting, it
was
necessary
to rank the
risk factors
for HTN in
a
university
setting in
Ekpoma,
Edo State,
Nigeria.
All
of
the
university's
faculties
and
service
divisions were
used to pick
1,600 academic
and
non-
academic staff
members
at
random,
who
might be senior
or
junior
personnel.
Risk factors
of HTN
The total crude
prevalence
was
33%,
whereas
junior
employees
had a prevalence of
23.8% and senior
staff
had
a
prevalence
of
38.93%. In this
study, the male
senior staff had a
substantially higher
mean diastolic HTN
of 158.3 4.5. In this
study, kolanut was
the main risk factor,
and its effects were
more noticeable in
the senior staff.
Extra salt, alcohol,
cigarette smoking,
and
sex
were
additional
risk
factors.
The
study
demonstrated
the
significance
of
ranking
HTN
predictors so
that
adequate awareness
campaigns may be
planned to reduce
those risks and, as a
consequence,
marginalise
the
catastrophic effects
of HTN and its
complications.
4
0
.
Omuem
u et al.
2004
To
evaluate
the degree
of
knowledge
about high
blood
pressure,
therapy,
and control
in a rural
population
in Nigeria's
Edo State.
Participants
were
chosen
through cluster
sampling, and a
researcher-
administered
questionnaire
was utilised to
gather the data.
Awareness,
Treatment
and Control
of HTN
HTN
prevalence
was 20.2%. 18.5%
of the hypertensives
knew they had high
blood
pressure.
Females had higher
awareness, which
rose with age and
fell with increasing
educational
attainment. Of those
who were aware of
their issue, 77.3%
were
receiving
treatment, and of
those, 29.4% had
their blood pressure
under control.
According to the
study, this rural
population has poor
levels of knowledge
of
high
blood
pressure and its
management.
Therefore, the need
for
consistent,
population-based
HTN
screening
programs is
important.
4
1
.
Ordinio
ha
2013
To
determine
the
According to the
study, this rural
population has
Prevalence,
Awareness,
Treatment
The study found
that
this
rural
community had low
Due in large part to
their
improved
health-seeking
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prevalence
of
HTN
and
its
modifiable
risk factors
among the
lecturers at
the
University
of
Port
Harcourt
Medical
School.
poor levels of
knowledge
of
high
blood
pressure and its
management.
Therefore, the
need
for
consistent,
population-
based
HTN
screening
programs is
important.
and Control
of HTN
levels of awareness
of
high
blood
pressure status and
control.
Routine
population-based
HTN
screening
programmes
are
thus
urgently
needed.
behaviour and active
lifestyles, medical
school
instructors
had
a
lower
frequency of HTN
than the general
population.
4
2
.
Ordinio
ha
&
Brisibe
2013
To find out
how
common
HTN
is
among the
traditional
leaders of a
communit
y in Rivers
State,
Nigeria,
and
to
identify its
modifiable
risk
factors.
The study found
that this rural
population
knows
little
about
blood
pressure
problems
and
how to treat
them.
Therefore, it is
crucial to have
reliable,
population-
based
HTN
screening
programmes.
Prevalence
of HTN and
its
modifiable
risk factors
The mean systolic
and diastolic blood
pressures in the
study
population
were 149 and 98
millimetres
of
mercury,
respectively.
The
HTN
prevalence was
68.9%.
The
majority (63.01%)
of the chiefs who
had
HTN were
conscious of their
condition and were
taking medication to
treat it (50.68%).
There
were
no
underweight chiefs,
and the majority
were
either
overweight
(51.89%) or obese
(26.42%). Almost
all of the chiefs
(92.45%)
used
alcohol frequently,
and 24.53% smoke
cigarettes right now.
Compared to the
general population,
traditional
leaders
had
a
greater
frequency of HTN.
Their advanced age
and acculturation are
likely to blame for
this.
4
3
.
Oyeyem
i
&
Adeyem
i
2013
To
investigate
the
association
between
risk factors
Workers were
sourced
from
places
of
employment
with
various
levels
of
Prevalence,
Awareness,
Treatment
and Control
of HTN
Women were more
likely to be obese, to
report having a
diagnosis
of
a
component of the
metabolic
Adults in Nigeria
who were employed
had low levels of
physical
activity,
which
was
associated
with
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for CVD
and
physically
active
behaviours
in an adult
working
population
in
Maiduguri,
Nigeria.
occupational
engagement. In
Maiduguri,
North-East
Nigeria,
six
workplaces
totaling
more
than
100
people were
purposefully
hired
from
institutions
supported by the
federal or state
governments.
syndrome, and to be
less
physically
active than males (p
0.05).
When
compared to those
who described their
job as moderately or
highly
active,
individuals
with sedentary
lifestyles
were likely
to
collect less minutes
of MVPA (p 0.001).
BMI,
heart
rate, waist
circumference, and
blood pressure were
all
negatively
correlated with the
health-improving
moderate-to-
vigorous physical
activity (MVPA) (p
0.05).
harmful CVD risk
factors.
In
Maiduguri, Nigeria,
encouraging
physical activity that
improves health may
be crucial for the
prevention
and
management
of
CVD among the
employed
population.
4
4
.
Ugwuja
et al.
2015
To
ascertain
the
prevalence
and causes
of HTN in
the
rural
communit
y
of
Igbeagu, in
South
Eastern
Nigeria.
No
clear
sampling
strategy
was
provided.
Prevalence,
Awareness,
Treatment
and Control
of HTN
Incidence of HTN
was 23.2%. HTN
was correlated with
age,
red
meat
intake, BMI, and the
proportion
of
children
in
the
family. Only age
and
BMI
were
identified
as
independent
risk
variables for HTN
by
regression
analysis.
Although
the
frequency of HTN
and its risk factors
were consistent with
other
studies
conducted
in
Nigeria, it is still
unclear how the
frequency
of
children
in
a
household and HTN
are
related.
To
reduce the high HTN
prevalence in
this
population, efforts
are required.
4
5
.
Ulasi et
al.
2010
To
quantify
the
prevalence
of
the
cardiometa
bolic
syndrome
(CMS) in
relation to
To
ensure
proportionate
representation,
2/3
of
respondents
were
chosen
from the semi-
urban
region,
while the last
third was chosen
Prevalence,
Awareness,
Treatment
and Control
of HTN
In
the
HTN
population,
the
prevalence of CMS
increased to 34.7%
and
24.7%,
respectively, from
the
general
prevalence of 18%
in the semi-urban
community
and
The high frequency
of CMS, particularly
in the population
with HTN, in semi-
urban
areas
emphasises
the
double burden of
illness in emerging
nations. The lesson
is
that
non-
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HTN
in
semi-rural
and rural
population
s in South-
East
Nigeria.
from the rural
community.
10% in the rural
community.
Hyperglycemia,
abdominal obesity,
and
hypertriglyceridae
mia all had higher
prevalence rates in
the
general
population in both
communities
combined than in
the
hypertensive
groups, which were
respectively 21.2%,
55.0%, and 31.3%.
Every other co-
morbidity, with the
exception of low
HDL
cholesterol,
was greater in the
hypertensive group
than it was in the
general population.
communicable
illnesses
should
not be overlooked
while diseases are
being dealt with in
these nations.
4
6
.
Ulasi et
al.
2011
To find out
how
common
HTN is in a
market
neighbour
hood
in
Enugu,
Nigeria.
No
clear
sampling
strategy
was
provided.
Prevalence
of HTN
42%
of
the
population
who
underwent
screening
for
hypertension
was
used to estimate
prevalence. Of this
group, 70.6% were
unaware of their
hypertension prior
to the test. More
males than females
had hypertension.
HTN
prevalence
rose
with
age
starting at 5.4% in
the age range.
This study used a
random sample of
market participants.
HTN
was
diagnosed on
the
average of three
blood
pressure
readings taken at one
time, which may
have had an impact
on the prevalence of
HTN in this research
as a whole.
4
7
.
Wahab
et al.
2006
To
ascertain
the
prevalence
of obesity
and
overweight
in a group
Until
the
appropriate
sample size was
reached,
subjects
were
successively
recruited using
the convenience
Prevalence
of HTN
53.3% and 21.0% of
people
were
overweight
or
obese, with females
having
a
substantially greater
prevalence
than
men (overweight:
In northern Nigeria,
obesity
is
quite
prevalent,
and
women
are
disproportionately
afflicted.
Female
sex,
elevated
cholesterol,
and
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of
urban
Nigerians,
as well as
the
variables
that
are
separately
linked with
obesity.
sampling
approach.
62.0% vs. 41.9%, p
0.001;
obesity:
29.8% vs. 9.3%, p
0.001). In univariate
analysis,
women
and
those
with
HTN,
hypercholesterolem
ia,
and
hyperuricemia had
increased
probabilities
of
being
obese.
However,
female
sex,
hypercholesterolem
ia,
and
hyperuricaemia
were independently
related with obesity
in
multivariate
analyses.
elevated uric acid
levels
are
all
independently
linked to the high
occurrence.
To
lessen this weight
and avoid other
NCDs, public health
education
is
critically needed.
4
8
.
Wokoma
et al.
2011
To
ascertain
the
prevalence
and trend
of BP in a
rural area
of Rivers
State,
Nigeria.
The individuals
for this survey
were chosen at
random from a
simple sample
of all subjects
who
had
previously
consented
to
take part in the
research.
Prevalence,
Awareness,
Treatment
and Control
of HTN
32.2% of people
worldwide
had
systolic
HTN.
Diastolic pressure
revealed pre-HTN
in 49 (32.2%) of the
participants, HTN
grade
1
in
21(13.8%),
and
HTN grade 2 in 15
(9.8%),
for
a
diastolic
HTN
prevalence rate of
23.6%. The overall
frequency of HTN
among
the
participants
was
27.9%. In 26.9% of
the
individuals,
significant
proteinuria
was
found. Blood sugar
and
BMI
were
rising indicators of
high diastolic BP.
It
was
not a
community-wide BP
survey that included
every
residence.
Only
individuals
who responded to
the
community
mobilisation
for
health outreach were
examined.
This
restricts the number
of the population
under investigation
and
could
have
resulted in some
selection bias.
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Appendix 3: Quality Appraisal
S/
N
Author
Sampling
Design
Statistical
Analysis
Case
Ascertainmen
t
Quality
Score
Quality
Rating
1.
Adebayo et al., 2013
1
1
1
3
Moderate
2.
Adedoyin et al., 2008
1
1
2
4
High
3.
Adedoyin et al., 2012
1
1
1
3
Moderate
4.
Adika et al., 2011
1
1
2
4
High
5.
Agaba et al., 2014
1
1
2
4
High
6.
Akinbodewa et al., 2014
1
1
2
4
High
7.
Akpa et al., 2008
1
1
2
4
High
8.
Akpan et al., 2015
1
1
1
3
Moderate
9.
Amira et al., 2012
1
1
1
3
Moderate
10. Amole et al., 2008
1
1
1
3
Moderate
11. Andy et al., 2012
1
1
1
3
Moderate
12. Asekun-Olarinmoye
et
al., 2013
1
1
1
3
Moderate
13. Awosan et al., 2013
1
1
1
4
High
14. Bello-Ovosi et al., 2017
1
1
2
4
High
15. Chukwuonye et al., 2013 1
1
2
4
High
16. Egbi et al., 2013
1
1
1
3
Moderate
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International Journal of Medical Science and Public Health Research
17. Ejim et al., 2006
1
1
2
4
High
18. Ekanem et al., 2012
1
1
2
4
High
19. Ekpe & Elemi, 2016
1
1
1
3
Moderate
20. Ekwunife et al., 2009
1
1
2
4
High
21. Emerole et al., 2007
1
1
1
3
Moderate
22. Erhun et al., 2003
1
1
1
3
Moderate
23. Ezejimofor et al., 2014
1
1
1
3
Moderate
24. Funke et al., 2013
1
1
2
4
High
25. Hendriks et al., 2012
1
1
2
4
High
26. Ibekwe et al., 2015
1
1
1
3
Moderate
27. Idris et al., 2020
1
1
2
4
High
28. Ige et al., 2013
1
1
2
4
High
29. Mbah et al., 2012
1
1
1
3
Moderate
30. Murthy et al., 2013
1
1
2
4
High
31. Odili et al., 2008
1
1
2
4
High
32. Ofuya, 2007
1
1
1
3
Moderate
33. Ogah et al., 2012
1
1
2
4
High
34. Oghagbon et al., 2007
1
1
1
3
Moderate
International Journal of Medical Science and Public Health Research
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International Journal of Medical Science and Public Health Research
35. Oguoma et al., 2015
1
1
2
4
High
36. Okafor et al., 2014
1
1
1
3
Moderate
37. Oladapo et al., 2005
1
1
2
4
High
38. Olisa & Oyelola, 2009
1
1
2
4
High
39. Omorogiuwa et al., 2008 1
1
1
3
Moderate
40. Omuemu et al., 2004
1
1
1
3
Moderate
41. Ordinioha, 2013
1
1
1
3
Moderate
42. Ordinioha & Brisibe,
2013
1
1
1
3
Moderate
43. Oyeyemi & Adeyemi,
2013
1
1
1
3
Moderate
44. Ugwuja et al., 2015
1
1
1
3
Moderate
45. Ulasi et al., 2010
1
1
1
3
Moderate
46. Ulasi et al., 2011
1
1
1
3
Moderate
47. Wahab et al., 2006
1
1
1
3
Moderate
48. Wokoma et al., 2011
1
1
1
3
Moderate
