The article presents the results of scientific research on testing the vaccine - "Enterovak - 5" in the farm of the Kushtepa district of the Fergana region "Yokub ota". The results of determining the dynamics of the titer of antiviral and bacterial antibodies in the blood serum of cows when immunized with the associated inactivated vaccine “Enterovak - 5” are given. It has been established that immunized cows have significantly increased antibodies both against viruses - causative agents of viral infections, and against Escherichia and Proteus
The article gives a brief description of viral diarrhea, rota- and coronavirus infection, colibacillosis and proteosis of calves. data on the effect of the blood of cows vaccinated with the activated, associated vaccine "Enterovak-5" against viral diarrhea, rota, coronavirus infection, colibacteriosis and proteosis on the hematological indicators of calves. It was found that this vaccine does not have a negative effect on the hematological parameters of the blood of vaccinated cows.