Significant differences were found in the frequency of occurrence of the FSHR rs6166 gene in patients with premature ovarian failure with the GG versus GA + AA genotype, in comparison with the control group. The most favorable / projecting genotype for FSHR G> A rs6166 is the GG genotype, while the AA genotype is risky. In case of premature ovarian failure, the FSHR rs6165 gene docs not have significant differences when comparing the group of patients with the control.
Based on the results of the study, the prevalence of low bone mineral density in patients with premature ovarian failure was determined. A complex assessment of the factors that play an important role in the reduction of BMD in patients with premature ovarian failure: the age factor and the level of sex hormones.