The search for new sources of highiy active drugs based on iocai raw materials is an urgent task of modern science, it is known that iicorice root is widely used in various sectors of the economy, the main component of it is glycyrrhizic acid. The presence of anti-inflammatory activity, iow toxicity and iack serious side effects make new synthetic derivative of glycyrrhizic acid promising for medicine compounds.
The purpose of the study. To study the antiulcer activity glycerinate on an experimental model of neurogenic uicers caused by 24-hour immobilization of animals and to identity the mechanism of antiulcer activity.
In experiments on white rats it was established that administration of heliotrine during a month induced severe damage to the liver characterized by enhancement of lipid peroxidation, a decrease of enzyme activities - superoxide dismutase and catalase. Liquorice, immortelle flowers and mumie inhibited manifestation of heliotrine hepatitis and exerted antioxidant action. In combined use of natural compounds their antioxidant action increases.