MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-23
Часть–3_ Апрель –2025
199
LIVER PHYSIOLOGY AND ITS FUNCTIONS
Ruzieva Gulchekhra Atoevna
Afshonа Technical College of Public Health named after Abu Ali Sino -
generalprofessional teacher of natural sciences
Avezova Nafisa Najmiddinovna
Afshona is a teacher of the department of pharmacology at the Technical
College of Public Health named after Abu Ali Sino
Abstract The liver is a vital organ that plays a crucial role in maintaining
homeostasis within the human div. It is responsible for various physiological
functions, including metabolism, detoxification, protein synthesis, and bile
production. This article provides an overview of liver physiology and its essential
functions.
Keywords: Liver, metaboliz
Introduction
The liver is the largest internal organ in the human div,
weighing approximately 1.5 kg in an adult. It is located in the upper right quadrant of
the abdomen and performs a wide range of functions essential for survival. The liver
receives blood from both the hepatic artery and the portal vein, allowing it to filter
and process nutrients, toxins, and metabolic byproducts.
Metabolic Functions
The liver plays a central role in metabolism, including
carbohydrate, lipid, and protein metabolism. It regulates blood glucose levels by
storing glucose as glycogen and releasing it when needed. The liver also synthesizes
cholesterol, lipoproteins, and fatty acids, as well as deaminating amino acids and
converting ammonia into urea for excretion.
Detoxification and Excretion
One of the most vital functions of the liver is
detoxification. It metabolizes drugs, alcohol, and harmful substances, converting
them into less toxic compounds that can be excreted through urine or bile. The liver
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-23
Часть–3_ Апрель –2025
200
also removes bilirubin, a byproduct of red blood cell breakdown, preventing jaundice
and other disorders.
Protein Synthesis
The liver is responsible for producing various essential
proteins, including albumin, clotting factors, and transport proteins. Albumin helps
maintain oncotic pressure and transports hormones and drugs. Clotting factors are
necessary for blood coagulation, preventing excessive bleeding.
Bile Production and Digestion
The liver produces bile, a digestive fluid that
aids in the emulsification and absorption of fats. Bile is stored in the gallbladder and
released into the small intestine when needed. It contains bile salts, cholesterol, and
waste products such as bilirubin.
Conclusion
The liver is a multifunctional organ that plays a vital role in
metabolism, detoxification, protein synthesis, and digestion. Maintaining liver health
is essential for overall well-being, and liver diseases can have severe consequences.
Further research into liver physiology can help develop advanced treatments for
hepatic disorders.
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Rashed, A. H. (2021). Liver functions and its metabolic role: A review.
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