MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
139
BACTERIAL VAGINOSIS IS A DANGEROUS DISEASE
Asian International University
Temirova Dilnoza Olimjonovna
Bacterial vaginosis (BV) is a disorder of the vaginal microflora that occurs
when the normal microbiota is replaced by high concentrations of anaerobic bacteria.
Statistics from various authors show that 40–50% of all cases of the appearance or
change of vaginal discharge are caused by bacterial vaginosis and approximately 25
to 50% of women today suffer from this disease [1–5].
The incidence of this disorder often depends on the population of women
examined. It is 17–19% in family planning clinics and among female students
observed in student clinics; 24–37% – among women undergoing treatment in
sexually transmitted disease clinics; 20–25% – among pregnant women [6, 7]. The
presence of this disease is observed in 30–50% of African American women, and in
10–20% of white women [8, 9].
Given the frequency of BV relapses, treatment and prevention of disease
relapses are currently an important problem in pharmacotherapy. The ineffectiveness
of antimicrobial drugs occurs due to the lack of a complete understanding of the
pathogenesis of BV, as well as the causes of its relapses, which affects the
effectiveness of treatment
This review examines the latest data on the pathogenesis of BV, treatment
methods, and possible strategies to reduce disease relapses. Currently, new strategies
to improve the effectiveness of disease treatment include changes in drug dose,
treatment duration, long-term prophylactic regimens, and the use of biofilm
disrupting agents. the use of high-dose suppositories containing metronidazole in
combination with an antifungal agent, usually miconazole, which is also useful for
mixed bacterial-fungal infections of the vagina. It is likely that future therapy will
involve the simultaneous use of several components, including combinations of
antibiotics, antibiofilm agents and probiotics.
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
140
Key words: bacterial vaginosis, vaginal microflora, treatment, metronidazole,
clindomycin, suppositories.
The prevalence of BV varies by country and population, but a recent
systematic review and meta-analysis estimated the global prevalence of BV among
women of reproductive age to be 23–29%.
BV increases the risk of contracting HIV, as well as the acquisition and
onward transmission of other STIs and, if untreated, can lead to adverse consequences
in pregnancy
The main similarity between AB and BV is that in both conditions there is a
significant decrease in the amount lactobacilli, leading to a decrease in the
concentration of lactic acid and, accordingly, an increase in the pH of the vaginal
environment, and their replacement by conditionally pathogenic microorganisms. The
differences between these diseases are significant. BV is characterized by the absence
of inflammation and the presence of a large amount of anaerobic microflora. Usually
involved in the development of BV
Gardnerella vaginalis, Atopobium vaginae, Prevotella spp., Porphyromonas
spp., Bacteroides spp., Peptostreptococcus spp., Mobiluncus spp., Megasphaera spp.,
Leptotrichia spp., Dialister spp., bacteria associated with bacterial vaginosis (bacterial
vaginosis associated bacteria) BVAB1, BVAB2, BVAB3, belonging to the order
Clostridiales. AB in its typical presentation is characterized by an increased
inflammatory response and/or severe signs of atrophy of the vaginal epithelium and
the presence of a moderate amount of commensal intestinal microflora
Most often, Streptococcus spp is detected in AV. (up to 59% of cases),
Staphylocuccus aureus (up to 42%), coagulase-negative staphylococci (up to 37%),
Escherichia coli (up to 23%) [1]. BV is the most common disorder of the vaginal
microecosystem in women of reproductive age. The prevalence of the disease varies
extremely widely (7–68%) depending on region, ethnicity/race, and population
studied [2].
Thus, among women with vaginal discharge, the incidence of BV is 20–30%,
and among patients at high risk of sexually transmitted infections (STIs), it reaches
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
141
50–60% [3]. The main clinical manifestation of BV is specific discharge formed as a
result of fermentation of normal vaginal mucin gel. Amines give the secretions a
specific (“fishy”) odor.
At an alkaline pH, the non-volatile salts of these compounds are converted
into volatile amines, and the “fishy” odor becomes noticeable or intensifies. Signs of
vulvovaginitis are not typical for BV (unless it is accompanied by trichomoniasis or
candidiasis). Many women with BV have no symptoms. Research in recent years
shows that BV not only reduces a woman’s quality of life, but is also associated with
a number of inflammatory diseases of the genitourinary tract, and is one of the
common causes of pregnancy complications [4–7]. The disease often takes a relapsing
form: 60% of women experience relapses of BV within 12 months after treatment [8].
The prevalence of AV among women of reproductive age, according to different
authors, varies from 5 to 24% [1, 9, 10]. In a study by M. Jahic et al. (2013) AB
frequency in women with signs of vaginitis was 51% [11]. In women with a normal
pregnancy, AV was detected in 3–10% of cases [12–14]. The clinical picture of AB
is similar to the clinical picture of trichomoniasis: profuse yellow or greenish-yellow
discharge, burning and itching in the vagina and in the area of the vaginal vestibule,
dyspareunia. During a gynecological examination, swelling, hyperemia, petechial
rashes are noted, superficial erosions of the mucous membrane of the cervix, walls
and vestibule of the vagina. As with trichomoniasis, the pH of vaginal discharge is
elevated, but unlike trichomoniasis, in which the amine test is often positive, the
amine test for AB gives a negative result. Symptoms may be present for a long time
(months and sometimes years), with varying degrees of severity. Not uncommon
cases when patients receive several courses of therapy for AV without visible results.
Many women have microscopic signs of AV in the absence of symptoms, but the
frequency of such asymptomatic forms of AV is unknown. The severe form of AV is
very similar to desquamative inflammatory vaginitis, a clinical syndrome
characterized by diffuse exudative inflammation, desquamation of parabasal
epithelial cells, abundant purulent discharge, increased pH value of the vaginal
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
142
environment [15–17]. In 1994 J.D. Sobel retrospectively described 51 cases of this
disease [17].
The results of the studies allow us to distinguish two variants of the clinical
course of BV: asymptomatic and with clinical symptoms. It should be noted that the
majority of women (50–75%) who are diagnosed with bacterial vaginosis have no
symptoms of this condition at all. In this case, we talk about the so-called
asymptomatic form of bacterial vaginosis. With an asymptomatic course, there are no
clinical manifestations of the disease along with positive laboratory signs. Other
patients with BV, as a rule, complain of copious white or gray discharge from the
genital tract, often with a “fishy” o especially after unprotected intercourse or during
menstruation. Seminal fluid has a pH of 7.0, so after ejaculation, the vaginal pH
increases, as a result of which amines become free and cause an unpleasant odor.
Thus, an increase in unpleasant odor after sexual intercourse serves as a definite
differential diagnostic sign of BV.
The duration of these symptoms can be years. As the process progresses, the
discharge acquires a yellowish-greenish color, becomes thicker, foamy, slightly
viscous and sticky, and is evenly distributed over the walls of the vagina. The amount
of leucorrhoea varies from moderate to very profuse. BV itself does not pose a threat
to health, but prolonged and abundant
vaginal discharge is accompanied by a significant decrease in a
woman’s quality of life (sexual function is impaired, performance decreases, etc.).
According to the recommendations of the Center for Disease Control
(CDC), the treatment regimen for BV includes:
• metronidazole orally 500 mg 2 times a day for 7 days;
• clindamycin cream 2% – 1 full applicator (5 g) intravaginally at
night for 7 days;
• metronidazole gel 0.75% – 1 applicator (5 g) intravaginally at night
for 5 days.
The following are considered alternative treatment regimens:
• metronidazole orally 2 g once;
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
143
• clindamycin orally 300 mg 2 times a day for 7 days;
• clindamycin 100 mg intravaginally at night for 3 days.
According to the recommendations of the World Health Organization
(WHO), the standard treatment for bacterial vaginosis is taking metronidazole 400 or
500 mg twice a day for 7 days or 2 g once. The European Association for STIs
(IUSTI/WHO) also recommends metronidazole 400 or 500 mg twice a day for 7 days
or 2 g once or clindamycin vaginal cream 2% 5 g at night for 7 days. According to
2010 Federal Guidance.
(Formular system), for BV it is recommended:
• clindamycin 2% 5 g 1 r/day (at night) intravenously (using a
standard applicator) for 3 days;
• metronidazole po 0.5 g every 12 hours for 7 days;
• metronidazole IV 1 tablet. (0.5 g) at night, course 10 days;
• metronidazole gel 0.75% (5.0 g) at night, course 5 days.
A randomized clinical trial using placebo control examined daily
vaginal metronidazole for 16 weeks [22]. As a result, 70% of women in the treatment
group showed no symptoms of BV, compared with 30% in the placebo group. After
treatment ended, relapses occurred in 65% of women in the treatment group at 12
months and in 80% of women in the placebo group. In addition, in patients
Those who used vaginal cream metronidazole were more likely to
have vulvovaginal candidiasis (p = 0.02).
Taking into account the above, it seems relevant to use combination
drugs for the treatment of BV, containing, in addition to the antibacterial, also an
antimycotic component. One such combination drug is Neo-Penotran, containing 500
mg of metronidazole and 100 mg
• miconazole nitrate in a convenient form in the form of vaginal pessaries,
which have virtually no local irritating effect on the vaginal mucosa, ensuring rapid
solubility and good acceptability for patients, which distinguishes them favorably
from the dosage form - vaginal tablets. Thanks to the combined antibacterial,
antiprotozoal and antimycotic action, the presented combination has high clinical
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
144
effectiveness. According to various authors [2], the cure rate for BV with the use of
Neo-Penotran reaches 96–98%. The drug is prescribed 1 vaginal suppository 2 times
a day for 7 days.
Summary. Bacterial vaginosis is now very common and cases of relapse of
the disease are observed. This is due to the fact that patients do not complete the full
course of treatment together.
with a sexual partner, as well as with reduced immunity or frequent regime
changes. sexual partners. Therefore, I believe that the main task required of
gynecologists is to give the patient a complete understanding of the treatment
procedure and disease prevention. Every attentive woman should undergo medical
examinations on time and lead a healthy lifestyle.
LITERATURA
1.
Temirova, D. O. (2024). Diagnosis of Cervical Erosion.
American Journal of
Bioscience and Clinical Integrity
,
1
(11), 84-89.
2.
ZHUMAEVA,
D.
(2024).
OPTIMIZATION
OF
METHODS
OF
DIAGNOSTICS OF VARIOUS FORMS OF ENDOMETRIOSIS IN WOMEN OF
REPRODUCTIVE AGE.
Valeology: International Journal of Medical Anthropology
and Bioethics (2995-4924)
,
2
(9), 120-125.
3.
Абдукаримов, У. Г., Ихтиярова, Г. А., & Джумаева, Д. Р. (2024). Скрининг
Рака Молочной Железы: Настоящее И Будущее. Обзор Литературы.
Research
Journal of Trauma and Disability Studies
,
3
(2), 144-148.
4.
Хикматова, Н. И., & Жумаева, Д. Р. (2023). Инвазивные И Неинвазивные
Методы Диагностики Заболевания Молочных Желез.
Central Asian Journal of
Medical and Natural Science
,
4
(6), 652-658.
5.
D.R.Zhumaeva,
D.R.Zhumaeva (2024)
The
State
of
the
Vaginal
Microbiocenosis, Bacterial Vaginosis andits Treatment Options.
American
Journal of Bioscience and Clinical Integrity, 1 (11). pp. 78-83. ISSN 2997-7347
6.
ERGASHEVA,
G.
T.
(2024).
OBESITY
AND
OVARIAN
INSUFFICIENCY.
Valeology: International Journal of Medical Anthropology and
Bioethics
,
2
(09), 106-111.
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
145
7.
Ergasheva, G. T. (2024). Modern Methods in the Diagnosis of Autoimmune
Thyroiditis.
American Journal of Bioscience and Clinical Integrity
,
1
(10), 43-50.
8.
Tokhirovna, E. G. (2024). COEXISTENCE OF CARDIOVASCULAR
DISEASES IN PATIENTS WITH TYPE 2 DIABETES.
TADQIQOTLAR. UZ
,
40
(3),
55-62.
9.
Toxirovna, E. G. (2024). DETERMINATION AND STUDY OF GLYCEMIA
IN PATIENTS WITH TYPE 2 DIABETES MELLITUS WITH COMORBID
DISEASES.
TADQIQOTLAR. UZ
,
40
(3), 71-77.
10.
Toxirovna, E. G. (2024). XOMILADORLIKDA QANDLI DIABET
KELTIRIB
CHIQARUVCHI
XAVF
OMILLARINI
ERTA
ANIQLASH
USULLARI.
TADQIQOTLAR. UZ
,
40
(3), 63-70.
11.
Toxirovna, E. G. (2024). QANDLI DIABET 2-TIP VA KOMORBID
KASALLIKLARI
BO’LGAN
BEMORLARDA
GLIKEMIK
NAZORAT.
TADQIQOTLAR. UZ
,
40
(3), 48-54.
12.
Tokhirovna, E. G. (2024). MECHANISM OF ACTION OF METFORMIN
(BIGUANIDE) IN TYPE 2 DIABETES.
JOURNAL OF HEALTHCARE AND LIFE-
SCIENCE RESEARCH
,
3
(5), 210-216.
13.
Tokhirovna, E. G. (2024). THE ROLE OF METFORMIN (GLIFORMIN) IN
THE
TREATMENT
OF
PATIENTS
WITH
TYPE
2
DIABETES
MELLITUS.
EUROPEAN
JOURNAL
OF
MODERN
MEDICINE
AND
PRACTICE
,
4
(4), 171-177.
14.
Эргашева, Г. Т. (2024). Эффект Применения Бигуанида При Сахарным
Диабетом 2 Типа И Covid-19.
Research Journal of Trauma and Disability
Studies
,
3
(3), 55-61.
15.
Toxirovna, E. G. (2024). QANDLI DIABET 2 TUR VA YURAK QON
TOMIR
KASALLIKLARINING
BEMOLARDA
BIRGALIKDA
KECHISHI.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В
МИРЕ
,
38
(7), 202-209.
16.
Мухиддинова, Х. С. (2024). РАЗВИТИЕ ЯИЧНИКОВ, ИХ
МОРФОЛОГИЯ
И
ОСОБЕННОСТИ
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
146
ФУНКЦИОНИРОВАНИЕ.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ
ИДЕИ В МИРЕ
,
55
(2), 134-141.
17.
Мухитдинова, Х. С. (2024). СОВРЕМЕННЫЕ ВЗГЛЯДЫ НА РАЗВИТИЕ
БАКТЕРИАЛЬНОГО
ВАГИНОЗА
У
ЖЕНЩИН
ФЕРТИЛЬНОГО
ВОЗРАСТА.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В
МИРЕ
,
55
(2), 97-103.
18.
Мухитдинова, Х. С. (2024). ЗАБОЛЕВАЕМОСТЬ СПИДОМ,
МОРФОЛОГИЧЕСКИЕ ОСОБЕННОСТИ БОЛЕЗНИ.
ОБРАЗОВАНИЕ НАУКА
И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ
,
55
(2), 104-112.
19.
Samikhovna, M. K. (2024). Clinical and Morphological Aspects of the
Functioning of the Lymphatic System.
International Journal of Alternative and
Contemporary Therapy
,
2
(9), 101-106.
20.
Samikhovna, M. K. (2024). MODERN VIEWS ON ACROMEGALY AND
IMMUNOMORPHOLOGY OF THIS DISEASE.
EUROPEAN JOURNAL OF
MODERN MEDICINE AND PRACTICE
,
4
(10), 179-183.
21.
Saloxiddinovna, X. Y. (2024). Modern Views on the Effects of the Use of
Cholecalciferol on the General Condition of the Bod.
JOURNAL OF HEALTHCARE
AND LIFE-SCIENCE RESEARCH
,
3
(5), 79-85.
22.
Халимова, Ю. С., & Хафизова, М. Н. (2024). МОРФО-
ФУНКЦИОНАЛЬНЫЕ И КЛИНИЧЕСКИЕ АСПЕКТЫ СТРОЕНИЯ И
РАЗВИТИЯ ЯИЧНИКОВ (ОБЗОР ЛИТЕРАТУРЫ).
TADQIQOTLAR. UZ
,
40
(5),
188-198.
23.
Халимова, Ю. С. (2024). Морфологические Особенности Поражения
Печени У Пациентов С Синдромом Мэллори-Вейса.
Journal of Science in
Medicine and Life
,
2
(6), 166-172.
24.
Xalimova, Y. S. (2024). Morphology of the Testes in the Detection of
Infertility.
Journal of Science in Medicine and Life
,
2
(6), 83-88.
25.
Халимова, Ю. С., & Хафизова, М. Н. (2024). ОСОБЕННОСТИ
СОЗРЕВАНИЕ И ФУНКЦИОНИРОВАНИЕ ЯИЧНИКОВ.
ОБРАЗОВАНИЕ
НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ
,
55
(2), 188-194.
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
147
26.
Хафизова, М. Н., & Халимова, Ю. С. (2024). МОТИВАЦИОННЫЕ
МЕТОДЫ
ПРИ
ОБУЧЕНИИ
ЛАТЫНИ
И
МЕДИЦИНСКОЙ
ТЕРМИНОЛОГИИ.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В
МИРЕ
,
55
(2), 165-171.
27.
Хафизова, М. Н., & Халимова, Ю. С. (2024). ИСПОЛЬЗОВАНИЕ
ЧАСТОТНЫХ ОТРЕЗКОВ В НАИМЕНОВАНИЯХ ЛЕКАРСТВЕННЫХ
ПРЕПАРАТОВ
В
ФАРМАЦЕВТИКЕ.
ОБРАЗОВАНИЕ
НАУКА
И
ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ
,
55
(2), 172-178.
28.
Saloxiddinovna, X. Y., & Ne’matillaevna, X. M. (2024). FEATURES OF THE
STRUCTURE OF THE REPRODUCTIVE ORGANS OF THE FEMALE
BODY.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ
,
55
(2),
179-183.
29.
Халимова, Ю. С., & Хафизова, М. Н. (2024). КЛИНИЧЕСКИЕ АСПЕКТЫ
ЛИЦ
ЗЛОУПОТРЕБЛЯЮЩЕЕСЯ
ЭНЕРГЕТИЧЕСКИМИ
НАПИТКАМИ.
TADQIQOTLAR. UZ
,
40
(5), 199-207.
30.
Халимова, Ю. С., & Хафизова, М. Н. (2024). КЛИНИЧЕСКИЕ
ОСОБЕННОСТИ ЗАБОЛЕВАНИЙ ВНУТРЕННИХ ОРГАНОВ У ЛИЦ,
СТРАДАЮЩИХ
АЛКОГОЛЬНОЙ
ЗАВИСИМОСТЬЮ.
TADQIQOTLAR.
UZ
,
40
(5), 240-250.
31.
Халимова, Ю. С., & Хафизова, М. Н. (2024). кафедра Клинических наук
Азиатский международный университет Бухара, Узбекистан.
Modern education
and development
,
10
(1), 60-75.
32.
Халимова, Ю. С., & Хафизова, М. Н. (2024). МОРФО-
ФУНКЦИОНАЛЬНЫЕ И КЛИНИЧЕСКИЕ АСПЕКТЫ ФОРМИРОВАНИЯ
КОЖНЫХ ПОКРОВОВ.
Modern education and development
,
10
(1), 76-90.
33.
Nematilloevna, K. M., & Salokhiddinovna, K. Y. (2024). IMPORTANT
FEATURES IN THE FORMATION OF DEGREE OF COMPARISON OF
ADJECTIVES IN LATIN.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ
ИДЕИ В МИРЕ
,
55
(2), 150-157.
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
148
34.
KHALIMOVA,
Y.
S.
(2024).
MORPHOFUNCTIONAL
CHARACTERISTICS OF TESTICULAR AND OVARIAN TISSUES OF
ANIMALS IN THE AGE ASPECT.
Valeology: International Journal of Medical
Anthropology and Bioethics
,
2
(9), 100-105.
35.
Salokhiddinovna, K. Y., Saifiloevich, S. B., Barnoevich, K. I., & Hikmatov, A.
S. (2024). THE INCIDENCE OF AIDS, THE DEFINITION AND CAUSES OF THE
DISEASE.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В
МИРЕ
,
55
(2), 195-205.
36.
Salokhiddinovna, K. Y. (2024). IMMUNOLOGICAL CRITERIA OF
REPRODUCTION AND VIABILITY OF FEMALE RAT OFFSPRING UNDER
THE INFLUENCE OF ETHANOL.
EUROPEAN JOURNAL OF MODERN
MEDICINE AND PRACTICE
,
4
(10), 200-205.
37.
Nematilloyevna, X. M., & Saloxiddinovna, X. Y. (2024). TIBBIYOT
FANLARIDA
MOTIVATSIYON
METODLAR.
Modern
education
and
development
,
16
(7), 31-42.
38.
Nematilloyevna, X. M., & Saloxiddinovna, X. Y. (2024). TURLI TIBBIY
TERMINLARNING
YASALISH
USULLARI.
Modern
education
and
development
,
16
(7), 68-78.
39.
Nematilloyevna, X. M., & Saloxiddinovna, X. Y. (2024). TIBBIY
TERMINOLOGIYADA TARJIMA MASALALARI.
Modern education and
development
,
16
(7), 43-56.
40.
Nematilloyevna, X. M., & Saloxiddinovna, X. Y. (2024). TIBBIY
TERMINOLOGIYADA TARJIMA MASALALARI.
Modern education and
development
,
16
(7), 43-56.
41.
Nematillaevna, K. M., & Salokhiddinovna, K. Y. (2024). NUMERALS IN
THE LATIN.
Modern education and development
,
16
(7), 57-67.
42.
Khalimova, Y. S. (2024). Features of Sperm Development: Spermatogenesis
and Fertilization.
American Journal of Bioscience and Clinical Integrity
,
1
(11), 90-
98.
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
149
43.
Sharapova, N. (2023). ARTERIAL GIPERTENZIYA VA SEMIZLIK
KASALLIKLARINING O’ZARO BOG’LIQLIK SABABLARI VA METABOLIK
SINDROMLAR.
Центральноазиатский журнал образования и инноваций
,
2
(11
Part 2), 174-179.
44.
Шарапова, Н. (2023). КЕКСА ВА ҚАРИ ЁШЛИ АЁЛЛАРДА БЕЛ
АЙЛАНАСИНИНГ ЖИСМОНИЙ ФАОЛЛИК БИЛАН БОҒЛИҚЛИГИ
ҚИЁСИЙ
ТАҲЛИЛИ.
Центральноазиатский
журнал
образования
и
инноваций
,
2
(12 Part 2), 127-133.
45.
Erkinjonovna, S. N. (2023). DIABETES MELLITUS IN PREGNANT
WOMEN.
Best Journal of Innovation in Science, Research and Development
, 110-
116.
46.
Erkinjonovna, S. N. (2024). CHARACTERISTICS OF DENTAL
PROSTHESES WEARING IN PATIENTS WITH TYPE 2 DIABETES
ACCORDING TO KIDNEY IMPAIRMENT.
PEDAGOG
,
7
(1), 84-88.
47.
Erkinjonovna, S. N. (2024). THE BEST WAYS TO CONTROL HIGH
BLOOD PRESSURE WITHOUT MEDICATION.
Journal of new century
innovations
,
47
(2), 175-183.
48.
Halimovna, M. M. (2021). The Role of Features of Linguocountrylearning in
Teaching English.
Central Asian Journal of Literature, Philosophy and
Culture
,
2
(10), 64-68.
49.
MAKHMUROVA, M. K. (2021, March). GRAMMATICAL CATEGORIES
IN GERMAN AND UZBEK. In
E-Conference Globe
(pp. 118-123).
50.
Махмурова, М. Х. (2021). METAFORALAR NUTQ SHAKLI
SIFATIDA.
МЕЖДУНАРОДНЫЙ ЖУРНАЛ ИСКУССТВО СЛОВА
,
4
(1-1).
51.
A'zamovna, A. R., Halimovna, M. M., & Bakhtiyorovna, N. M. (2019). The
matter of equivalence in English and Uzbek proverbs.
Test Engineering and
Management
,
81
(11-12), 1632-1637.
52.
Makhmurova, M. H. (2024). Applications of the Latin Language in Speech.
American Journal of Alternative Education
,
1
(8), 59-63.
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
150
53.
Махмурова, М. Х. (2024). Теоретикo-Литературное Развитие Учащихся
При Изучении Басен.
Miasto Przyszłości
,
54
, 1032-1035.
54.
Maxmurova,
M.
(2021).
ЎҚУВЧИ
БИЛИШ
ФАОЛИЯТИНИ
ФАОЛЛАШТИРИШДА ИЖОДИЙ ГРАФИК МАСАЛАЛАРНИ Auto CAD
ДАСТУРИ АСОСИДА ЕЧИШ.
ЦЕНТР НАУЧНЫХ ПУБЛИКАЦИЙ (buxdu.
uz)
,
3
(3).
55.
BABAYEVA, V. T., MAKHMUROVA, M. H., & NAZAROVA, G. K. (2021,
March). Studying language as the second language learners. In
E-Conference
Globe
(pp. 89-94).
56.
Salokhiddinovna, X. Y. (2023). Anemia of Chronic Diseases.
Research
Journal of Trauma and Disability Studies
,
2
(12), 364-372.
57.
Salokhiddinovna, X. Y. (2023). MALLORY WEISS SYNDROME IN
DIFFUSE LIVER LESIONS.
Journal of Science in Medicine and Life
,
1
(4), 11-15.
58.
Salohiddinovna, X. Y. (2023). SURUNKALI KASALLIKLARDA
UCHRAYDIGAN
ANEMIYALAR
MORFO-FUNKSIONAL
XUSUSIYATLARI.
Ta'lim innovatsiyasi va integratsiyasi
,
10
(3), 180-188.
59.
Халимова,
Ю.
С.
(2024).
КЛИНИКО-МОРФОЛОГИЧЕСКИЕ
ОСОБЕННОСТИ
ВИТАМИНА
D
В
ФОРМИРОВАНИЕ
ПРОТИВОИНФЕКЦИОННОГО ИММУНИТА.
ОБРАЗОВАНИЕ НАУКА И
ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ
,
36
(3), 86-94.
60.
Saloxiddinovna, X. Y. (2024). CLINICAL FEATURES OF VITAMIN D
EFFECTS
ON
BONE
METABOLISM.
ОБРАЗОВАНИЕ
НАУКА
И
ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ
,
36
(5), 90-99.
61.
Saloxiddinovna, X. Y. (2024). CLINICAL AND MORPHOLOGICAL
ASPECTS OF AUTOIMMUNE THYROIDITIS.
ОБРАЗОВАНИЕ НАУКА И
ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ
,
36
(5), 100-108.
62.
Saloxiddinovna, X. Y. (2024). MORPHOFUNCTIONAL FEATURES
BLOOD
MORPHOLOGY
IN
AGE-RELATED
CHANGES.
Лучшие
интеллектуальные исследования
,
14
(4), 146-158.
MODERN EDUCATION AND DEVELOPMENT
Выпуск журнала №-19
Часть–3_ Февраль –2025
151
63.
Saloxiddinovna, X. Y. (2024). CLINICAL MORPHOLOGICAL CRITERIA
OF LEUKOCYTES.
Лучшие интеллектуальные исследования
,
14
(4), 159-167.
64.
Saloxiddinovna, X. Y. (2024). Current Views of Vitamin D Metabolism in the
Body.
Best Journal of Innovation in Science, Research and Development
,
3
(3), 235-
243.
65.
Saloxiddinovna, X. Y. (2024). MORPHOFUNCTIONAL FEATURES OF
THE STRUCTURE AND DEVELOPMENT OF THE OVARIES.
EUROPEAN
JOURNAL OF MODERN MEDICINE AND PRACTICE
,
4
(4), 220-227.
