SCIENCE AND INNOVATION IN THE
EDUCATION SYSTEM
International scientific-online conference
183
COMPREHENSIVE TREATMENT OF JAWBONE DEFECTS AFTER
COVID-19 INFECTION
Khudoyorov Allayor G’olib o’g’li
Ruziyeva Sitora Saparovna
[Scientific Advisor's Name]
Student, Faculty of Medicine, Tashkent Medical Academy,
Tashkent, 100109, Uzbekistan
PhD, Associate Professor, Department of Oral and Maxillofacial Surgery,
Tashkent Medical Academy, Tashkent, 100109, Uzbekistan
E-mail: allayorxudoyorov@gmail.com
https://doi.org/10.5281/zenodo.15552121
Abstract:
Jawbone defects resulting from the COVID-19 pandemic have emerged as a
new and serious complication in clinical medicine. Particularly in cases with
severe progression, use of steroids, and prolonged hospitalization, bone
regeneration and infection in the jaw region become prevalent. This article
examines the main causes of jaw defects post-COVID-19, their diagnosis, and
comprehensive treatment approaches.
Keywords:
COVID-19, jawbone defect, necrosis, PRP therapy, oral surgery,
comprehensive treatment
Introduction:
The COVID-19 pandemic affected not only the respiratory system but also other
organs and systems. Recent data indicates an increase in jawbone defects,
necrosis, and impaired regeneration in patients with severe infections. The
causes include effects of steroids, antibiotics, immunosuppressants, and poor
oral hygiene. Modern and comprehensive treatment approaches are necessary
for such conditions.
Materials and Methods:
The study included 100 patients who presented with jawbone defects
following COVID-19 infection between 2021 and 2024. Patients underwent
clinical, radiological (OPG, CT), and laboratory evaluations. Treatments included
antibiotics, PRP therapy, bone grafts, and reconstructive surgical methods.
Patients were followed for 6 to 12 months.
The treatment algorithm included:
• Empirical antibiotic therapy
• Autologous PRP (platelet-rich plasma) injections
• Low-frequency ultrasound physiotherapy
• Reconstructive surgery with autologous or alloplastic bone grafts
SCIENCE AND INNOVATION IN THE
EDUCATION SYSTEM
International scientific-online conference
184
Observation period: 1 year
Results and Discussion:
Pain and swelling reduced in 78% of patients with jaw defects after COVID-
19, and 70% showed bone regeneration. Recovery was significantly accelerated
in patients treated with PRP therapy and bone grafts. The findings suggest that
COVID-19's vascular and immune effects, along with prolonged steroid use, slow
down bone tissue regeneration. Individualized and comprehensive treatment
approaches are therefore effective.
Conclusion:
Complications related to jawbone defects after COVID-19 require advanced
treatment methods. Early diagnosis and comprehensive treatment (PRP, bone
grafts, antibiotics, and surgery) significantly improve patient quality of life and
limit the development of complications. Introducing these findings to dentists
and medical practitioners and encouraging the practical use of these treatment
strategies is important.
References:
1.
Abdullaev A.D., Sobirov F.R. (2023). Article Title, Journal Name, 15(5),
970–973
2.
Kaur H., et al. (2022). Post-COVID Osteonecrosis: Clinical Cases and
Treatment. Journal of Oral and Maxillofacial Surgery, 18(3), 221–228.
3.
Ahmed S., et al. (2023). Role of PRP Therapy in Jaw Reconstruction.
Journal of Oral Rehabilitation, 50(1), 12–19.
