THEORETICAL ASPECTS IN THE FORMATION OF
PEDAGOGICAL SCIENCES
International scientific-online conference
71
WAYS TO IMPROVE THE QUALITY OF INTRAOPERATIVE
HEMOSTASIS IN RELATED HEPATOTRANSPLANTATION
Babadjanov A.Kh.
Turgunbaev E.K.
Makhmudov U.M.
Khaybullina Z.R.
State Institution "Republican Specialized Scientific and Practical Medical Center
for Surgery named after academician V. Vakhidov", Tashkent, Uzbekistan
https://doi.org/10.5281/zenodo.12741383
Abstract.
Bleeding is a major complication of liver transplantation and a
common cause of significant perioperative morbidity. To improve the results of
related transplantation of the right lobe of the liver by improving the technique
of stopping bleeding from the resection surface of the liver and veno-prosthetic
anastomoses. 33 liver lobe recipients were selected for this study. To assess the
effectiveness of the proposed method, two groups were formed: the main group
- 18 recipients, the comparison group - 15 recipients. The proposed method for
improving local hemostasis from the resection surface area and the suture line
of veno-prosthetic anastomoses due to the combined action of two hemostatic
agents reduced the duration of the general hemostatic stage of the operation
from 87.0±29.9 to 40.3±9.8 minutes. An improved method for increasing the
effectiveness of hemostasis in related transplantation is characterized by the
combined use of a hemostatic sponge and a powdered composition "Hemoben"
impregnated with plasma, which ensures activation and enhancement of the
action of both local agents on the resected surface of the liver.
Key words:
liver transplantation; hemostatic sponges; hemostasis;
"Hemoben".
The relevance of the problem:
Bleeding is a major complication of liver
transplantation and a common cause of significant perioperative morbidity.
Careful intraoperative hemostasis is required to reduce the risk of bleeding-
related complications. Although hemostasis has been achieved by suturing,
electrocoagulation, or surgical clamps, several hematopoiesis-promoting aids
have been developed over the past two decades. These products are broadly
divided into three groups: hemostatic agents for topical use, which cause blood
clotting on a bleeding surface, sealants that prevent blood from flowing out of
tissues, including vessels, and adhesives that hold tissues together.
Intraoperative funds for local hemostasis have become indispensable in the
modern surgical treatment of bleeding during operations.
THEORETICAL ASPECTS IN THE FORMATION OF
PEDAGOGICAL SCIENCES
International scientific-online conference
72
The aim of the study is
to improve the results of related transplantation of
the right lobe of the liver by improving the technique of stopping bleeding from
the resection surface of the liver and veno-prosthetic anastomoses.
Materials and methods:
33 liver lobe recipients were selected for this
study. To assess the effectiveness of the proposed method, two groups were
formed: the main group - 18 recipients, the comparison group - 15 recipients.
Results:
the proposed method for improving local hemostasis from the
resection surface area and the suture line of veno-prosthetic anastomoses due to
the combined action of two hemostatic agents reduced the duration of the
general hemostatic stage of the operation from 87.0±29.9 (95% CI: 70.5-103.5)
to 40.3±9.8 minutes (95% CI: 35.4-45.1; t=5.80; p<0.05).
Conclusions:
An improved method for increasing the effectiveness of
hemostasis in related transplantation is characterized by the combined use of a
hemostatic sponge and a powdered composition "Hemoben" impregnated with
plasma, which ensures activation and enhancement of the action of both local
agents on the resected surface of the liver, as well as contributes to the
formation of a hemostatic roller and strengthening the suture line of veno-
prosthetic anastomoses.
References:
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Lishchenko AN, Ibadov RA, Baibekov RR. Rodstvennaya transplantatsiya pecheni
v Respublike Uzbekistan: nyneshnee sostoyanie i perspektivy razvitiya [Living
related liver transplantation in the Republic of Uzbekistan: current status and
development prospects]. Khirurgiia (Mosk). 2023;(11):34-46. Russian. doi:
10.17116/hirurgia202311134. PMID: 38010016.
2. Babadjanov A.H., Khaybullina Z.R., Turgunbaev E.K., Matkarimov Sh.U.
Evaluation of hemostasis parameters in recipients following related
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and Artificial Organs. 2023;25(4):32-40. https://doi.org/10.15825/1995-1191-
2023-4-32-40
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Проблемы
биологии
и
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120(4):12-18.
DOI:
http://doi.org/10.38096/2181-5674.2020.4.00181
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