It has been established that under conditions of chronic inflammation of the lungs with bronchiectasis in children, destructive changes predominate in the structures of innate and acquired immunity of the airways, indicating their inability to effectively perform a protective function.
Blinova S.A., Oripov F.S., Khamidova F.M. Cellular and molecular mechanisms of lung malformations // Genes & Cells. - 2021. -Т. 41, №1.-С. 24-28.
Kozlov V.K., Lebedko O.A., Pichugina S.V., Sirotina-Karpova M.S., Evseeva G.P., Gandurov S.G. Topical issues of chronic nonspecific lung diseases in children // Bulletin of Physiology and Pathology of Respiration. - 2018.-№ 70.-С. 15-25.
Lunkova L.K., Makarova O.V., Kaktursky L.V. Morphology of lymphoid formations of the airways in bronchiectatic disease // Archives of Pathology. -2000.-VOL. 63,¹6.-P. 37-42.
Oleinik NA, Romaniuk FP. The catamnesis of children who underwent pneumonia // Pediatr. - 2016.-T.7, vol.3.-P.128-135.
Skobelev V.L., Galkin V. N., Illek Y.Y., Mischenko I.Yu. The state of immunological reactivity in children with chronic pneumonia, operated on for bronchiectasis // Vyatsky medic. -2000.-№1.-С.17-19. de Winther M.P.J., Palaga T. Editorial: Epigenetic Regulation of Innate Immunity //Front Immunol. 2021; 12: 713758.
GBD Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet 2015 Jan; 385(9963):117-71.
Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. 2023 GOLD Report. Available from: https://goldcopd.org/2023-gold-report-2/ Accessed 2023 Jan 31.
Greene C.M., Hiemstra P.S. Innate Immunity of the Lung //J Innate Immun. 2020 Jan; 12(1): 1–3.9.
Hajishengallis G., Li X., Mitroulis I., Chavakis T. Trained Innate Immunity and Its Implications for Mucosal Immunity and Inflammation// Adv Exp Med Biol.-2019; 1197:11-26.