URINARY TRACT INFECTIONS IN PREGNANCY: TREATMENT AND MANAGEMENT

Abstract

According to the literature, the incidence of gestational pyelonephritis (GP) is 5-10%, while the development of the disease increases the risk of intrauterine infection and miscarriage (Styazhkina S.N. et al., 2015). The study of the interaction between gestational pyelonephritis and pregnancy is relevant due to the high percentage of obstetric complications, negative perinatal outcomes and severe diseases in newborns, which emphasizes the medical and socio-economic significance of the problem. In chronic pyelonephritis, pregnancy is complicated by iron deficiency anemia (35-70%), premature termination of pregnancy at various stages (15-20%), chronic placental insufficiency (30-35%), preeclampsia (35-70%). 30-40% causes complications such as chronic uterine hypoxia (30-40%), fetal infection (20-30%) and growth retardation (12-15%). In chronic pyelonephritis, the ability of pregnant women to adapt to newborns is significantly impaired and the risk of early neonatal death increases.

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Abdukayumova, M. ., Akbarova , N., & Tilyavova , S. (2025). URINARY TRACT INFECTIONS IN PREGNANCY: TREATMENT AND MANAGEMENT. Young Scientists, 3(1), 54–55. Retrieved from https://inlibrary.uz/index.php/yosc/article/view/62323
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Abstract

According to the literature, the incidence of gestational pyelonephritis (GP) is 5-10%, while the development of the disease increases the risk of intrauterine infection and miscarriage (Styazhkina S.N. et al., 2015). The study of the interaction between gestational pyelonephritis and pregnancy is relevant due to the high percentage of obstetric complications, negative perinatal outcomes and severe diseases in newborns, which emphasizes the medical and socio-economic significance of the problem. In chronic pyelonephritis, pregnancy is complicated by iron deficiency anemia (35-70%), premature termination of pregnancy at various stages (15-20%), chronic placental insufficiency (30-35%), preeclampsia (35-70%). 30-40% causes complications such as chronic uterine hypoxia (30-40%), fetal infection (20-30%) and growth retardation (12-15%). In chronic pyelonephritis, the ability of pregnant women to adapt to newborns is significantly impaired and the risk of early neonatal death increases.


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YOSH OLIMLAR

ILMIY-AMALIY KONFERENSIYASI

in-academy.uz/index.php/yo

54

URINARY TRACT INFECTIONS IN PREGNANCY: TREATMENT AND

MANAGEMENT

Abdukayumova Mokhinabonu Dilshodovna

Akbarova Nozima Khusniddinovna

Clinical residents of the Department of Obstetrics and

Gynecology No. 1 of the Samarkand State Medical University

Tilyavova S.A.

Scientific supervisor: PhD, ass.

https://doi.org/10.5281/zenodo.14620586

Annotation.

According to the literature, the incidence of gestational pyelonephritis (GP)

is 5-10%, while the development of the disease increases the risk of intrauterine infection and
miscarriage (Styazhkina S.N. et al., 2015). The study of the interaction between gestational
pyelonephritis and pregnancy is relevant due to the high percentage of obstetric
complications, negative perinatal outcomes and severe diseases in newborns, which
emphasizes the medical and socio-economic significance of the problem. In chronic
pyelonephritis, pregnancy is complicated by iron deficiency anemia (35-70%), premature
termination of pregnancy at various stages (15-20%), chronic placental insufficiency (30-
35%), preeclampsia (35-70%). 30-40% causes complications such as chronic uterine hypoxia
(30-40%), fetal infection (20-30%) and growth retardation (12-15%). In chronic
pyelonephritis, the ability of pregnant women to adapt to newborns is significantly impaired
and the risk of early neonatal death increases.

Keywords:

gestational pyelonephritis, pregnancy, treatment, childbirth.

The aim of the research

: is to study the effect of GP on the course and outcome of

pregnancy.

Material and methods.

We observed 72 pregnant women who received treatment for

GP in the pregnancy pathology department of the Samarkand State medical university clinic in
the period 2023-2024.

The distribution of patients was as follows: 12-22 weeks - 25 (34.8%), 2331 not - 12

(22.4 s), 3238 - units-3 (47.3 diagnosed 30. Among the clinical symptoms in combination of
pregnancy and GP, the following prevailed: pain syndrome in the lumbar region on the right
(55,6%; n = 40), febrile div temperature (17.4%; n = 12), subfebrile temperature (27,8%; n
= 20), dysuria (16,7%; n = 12). According to the results of laboratory tests, leukocyturia was
detected in 42 pregnant women (58,4%), erythrocyturia - in 21 (29,1%), proteinuria - in 39
(54,1%), bacteriuria - in 14 (19.4%). Leukocytosis was noted in 13 (18%), and an increase in
ESR in 23 (32%). In all cases, treatment was carried out aimed at relieving the symptoms of
GP, with antispasmodic drugs used in 100%, and antibacterial drugs - only in 14 patients
(19,4%). | Further observation of pregnant women revealed the following complications of
gestation: threatened miscarriage (TM) was diagnosed in 52 (72,4%), anemia - in 30 (41,6%),
fetoplacental insufficiency (FPI) - in 7 (9%), chronic fetal hypoxia - in 6 (8%), preeclampsia
(PE) - in 4 (5%). In addition, recurrence of GP was observed in 26% of cases. Premature birth
(PL) at 23-32 weeks was recorded in 7 women (9,7%).

Conclusion

. Thus, according to our data, GP often develops at gestation periods of 32-38

weeks, is accompanied by an erased clinical picture, and negatively affects the further course
of pregnancy, increasing the risk of FPI, PE and TM.


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ILMIY-AMALIY KONFERENSIYASI

in-academy.uz/index.php/yo

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References

Shopulotova Z., Kobilova Z., Bazarova F. TREATMENT OF COMPLICATED GESTATIONAL PYELONEPHRITIS IN PREGNANTS //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 630-634.

Farkash E. et al. Acute antepartum pyelonephritis in pregnancy: a critical analysis of risk factors and outcomes //European Journal of Obstetrics & Gynecology and Reproductive Biology. – 2012. – Т. 162. – №. 1. – С. 24-27.

Айламазян Э.К., Репина М.А., Кузьминых Т.У. Акушерские кровотечения: профилактика и лечение//Акушерство и гинекология. - 2009. - Лº 3. - С. 15-20.

Акушерские кровотечения: пособие для врачей/ Репина М.А., Кузьминых Т.У., Зайкулина М.С. и

др./Под ред. Э. К. Айламазяна. - СПб.: Изд-во Н-Л., 2009. - 60 с.

Shopulotova Z., Kobilova Z., Shopulotov S. INFLUENCE OF PREECLAMPSIA ON SOMATIC DISEASES //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 778-780.

Kh K. Z., Kh Z. Z. FEATURES OF HEART RHYTHM DISORDERS AT DIFFERENT STAGES OF GESTATION //Talqin va tadqiqotlar ilmiy-uslubiy jurnali. – 2024. – Т. 2. – №. 54. – С. 272-277.

Khudoyarova D. R., Kh K. Z., Kh Z. Z. ARRHYTHMIAS IN PREGNANCY: TACTICS OF PATIENT MANAGEMENT //Eurasian Journal of Medical and Natural Sciences. – 2024. – Т. 4. – №. 9. – С. 119-123.

Shopulotova Z., Shopulotov S., Kobilova Z. MODERN VIEWS ON THE EFFECTIVENESS OF OZONE THERAPY //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 781-786.

Shopulotova Z., Kobilova Z., Bazarova F. TREATMENT OF COMPLICATED GESTATIONAL PYELONEPHRITIS IN PREGNANTS //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 630-634.

Bonnar J. Massive obstetric haemorrhage //Best Practice & Research Clinical Obstetrics & Gynaecology. – 2000. – Т. 14. – №. 1. – С. 1-18

Shopulotova Z., Kobilova Z., Shopulotov S. NEW OPPORTUNITIES FOR THE TREATMENT OF HYPERACTIVE BLADDER SYNDROME //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 770-773.

Shopulotova Z., Kobilova Z., Shopulotov S. URINATION DISORDERS IN PREGNANT WOMEN //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 774-777.

Ibragimov S. et al. UNVEILING EMOTIONS: A COMPREHENSIVE EXPLORATION OF ANALYZING, UNDERSTANDING, AND MANAGING EMOTIONAL RESPONSES //Collection of scientific papers «ΛΌГOΣ». – 2023. – №. November 24, 2023; Seoul, South Korea. – С. 228-230.

Khamzaevna Z. Z. ROLE OF BETA-BLOCKERS IN THE TREATMENT OF ARTERIAL HYPERTENSION Zubaydilloeva Zarina Khamzaevna //Independent Publishing Network Ltd Mailing address–MB# 1869, PO BOX 229, EGHAM, TW20 8WZ, UK. – 2020. – С. 20.