ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
72
REHABILITATION OF WOMEN WHO HAVE EXPERIENCED MOLAR
PREGNANCY
Nafosat Zokhidjon kizi Mamarizaeva
`The 1st year Master's degree resident of the Department of Obstetrics and
Gynecology №3 Samarkand State Medical University
e-mail: mnafosat27@gmail.com
Dildora Ismailovna Tugizova
Scientific supervisor: PhD
Samarkand State Medical University
https://doi.org/10.5281/zenodo.14649990
Annotation:
Molar pregnancy, or hydatidiform mole, is rare pathology of
the embryo that occurs due to a disruption in the development and growth of
the trophoblast (the outer layer of embryonic cells). Molar pregnancy is
classified as a type of gestational trophoblastic disease. The frequency of
occurrence varies significantly between different countries. 1 in every 200-300
pregnant women is diagnosed with hydatidiform mole in the territory of
Uzbekistan. Its frequency increased with age: in women over 40 years old, the
pathology is detected much more frequently. The fact that the principles of
monitoring women after evacuation of hydatidiform mole are not sufficiently
developed indicates the urgency of conducting research.
Keywords:
molar pregnancy, hydatidiform mole, choriocarcinoma, optimal
contraception, trophoblastic diseases
Objective:
Development of rehabilitation criteria for women who have
undergone molar pregnancy.
Materials and methods of research.
The study will be conducted at the
Maternity Complex №1 in Samarkand. A comprehensive approach will be
employed, including clinical, laboratory, ultrasound, and statistical research
methods.
The main group will consist of 43 women, who have undergone molar
pregnancy. A comprehensive approach will be employed, including clinical,
laboratory, ultrasound diagnostics methods. The expected objective of the work
is improvement of reproductive health in women who have undergone molar
pregnancy (hydatidiform mole) through the development of a comprehensive
approach aimed at physical and psycho-emotional recovery.
Research results.
In more than 20% of early pregnancies there will be
some vaginal bleeding. About one half of these end up by miscarrying. In the
remaining half, the bleeding subsides and the pregnancy continues to evolve
such that most will culminate in a healthy live birth. In less than 2% of cases of
ACADEMIC RESEARCH IN MODERN SCIENCE
International scientific-online conference
73
such bleeding the cause of early pregnancy bleeding is hydatidiform mole
(molar) pregnancy. With molar pregnancy, the roots of the trophoblast
(chorionic villi) undergo cystic degeneration and when the woman bleeds, these
cystic structures are passed in dark blood, giving rise to the common description
of “white currents floating in red currant jelly”.
More than 82% of molar pregnancies are benign (noncancerous). Treatment
involves complete emptying of the uterus as soon as the diagnosis is made. Even
in cases where a spontaneous passage of the molar tissue appears to be complete.
The reason is to avoid the development of an invasive mole (chorioadenoma
destruens), where the uterine wall is permeated by remaining tissue and to limit
the development of choriocarcinoma (where the molar tissue becomes
malignant). In the vast majority of properly managed cases however, outcome
after treatment is usually excellent. Close follow-up with serial quantitative blood
hCG testing, ultrasound and/or Magnetic Resonance Imaging (MRI) is essential.
After treatment, the woman must use very effective contraception for at least 6 to
12 months so as to avoid pregnancy in order to allow for proper follow-up.
Conclusion.
A comprehensive approach to improving the reproductive
health of women who have undergone molar pregnancy will help women enhance
their psychological well-being, quality of life, and chances for family planning.
The conducted research is aimed at preventing the recurrence of molar
pregnancy and the progression to malignant trophoblastic diseases. Timely
monitoring improves treatment outcomes for trophoblastic diseases. The use of
optimal contraception for one year after the evacuation of a molar pregnancy
prevents the recurrence of molar pregnancy and the development of malignant
trophoblastic diseases in women.
