158
DIAGNOSIS OF ARHYTHMOGENIC DYSPLASIA OF THE RIGHT
VENTRICLE IN CHILDREN
Makhmudova U.B., 117 group, II-pediatric faculty
Scientific adviser: assistant F.Sh. Saydalieva
TashPMI, Department of Propedeutics of childhood diseases, hematology
Relevance:
arrhythmogenic right ventricular dysplasia (ARVD), refers to the primary forms of
cardiomyopathy and is characterized by the replacement of the right ventricular (RV) myocardium with
fibrous and adipose tissue with the development of life-threatening arrhythmias. According to different
authors, the prevalence of arrhythmogenic right ventricular dysplasia is 1 per 1000 population; other
literature sources report that the incidence of ARVD is 1 per 5000 population. The ratio of the incidence
of the disease among men and women in the population is 3:1. The nonspecificity of symptoms, clinical
polymorphism, and the absence of a single method make the diagnosis of ARVD a difficult task.
Purpose of the study:
to study the diagnostic value of imaging methods in patients with ARVD.
Materials and methods:
a review and analysis of research and literature in recent years.
Results:
the basis of the disease is fibrous-fatty replacement of the pancreas
myocardium. In total, 20 ARVD criteria are distinguished: 9 CD and 11 MC; ARVD diagnosis is based
on a set of data from family history, ECG, visualizing, structural, histological and genetic changes.
Clinically, ARVD usually debuts with ventricular arrhythmias: extrasystole of various gradations, short
"runs" of ventricular tachycardia, and in some cases paroxysms of ventricular tachycardia, which can
lead to loss of consciousness during exercise or at rest. Since the arrhythmogenic focus is in the right
ventricle, ectopic ventricular complexes look like a blockade of the left bundle branch. In addition, there
may be changes in the depolarization and repolarization of the ventricular myocardium, detected in the
right precordial leads, as well as violations of the global and / or local contractility of the right ventricle
and changes in the structure of its myocardium according to echocardiography (EchoCG) and magnetic
resonance imaging (MRI). When assessing the structures of the heart, the method of echocardiography
and MRI of the heart can be distinguished. EchoCG imaging by the standard patient examination protocol
pays great attention to the left chambers of the heart; it does not always include a thorough analysis of
the pancreas, which is fraught with a decrease in the detection of pancreatic pathology. When using
echocardiography to diagnose ARVD, it is necessary to carefully assess the size of the right heart
chambers, myocardial thickness, local contractility of the RV myocardium, the presence of aneurysms,
as well as TAPSE, TASv and FAC. Cardiac MRI can significantly improve the effectiveness of the
diagnosis and treatment of ARVD.
Conclusions:
the diagnostic value of imaging methods for diagnosing ARVD by
echocardiography and MRI of the heart is high, provided that: thorough preparation for the study, the
implementation of the study protocol with a targeted study of not only LV structures, but the RV,
attentiveness, knowledge of the anatomy of the heart and pathology of the process and the diagnostician.
References:
1.
Мухитдинова
, X.,
Шорахмедов
, LU., &
Алимов
,
А
. (2020).
Циркадный ритм среднего
артериального давления в период токсемии ожоговой болезни взрослых
, in Library, 20(4), 71-
79.
извлечено от
https://inlibrary.uz/index.php/archive/article/view/19362
2.
Нечунаева
,
Екатерина Владимировна
, et al. "
Иммуно-биохимические показатели в ранней
диагностике хронической ишемии головного мозга
."
Бюллетень сибирской медицины
10.2
(2011): 142-146.
3.
Мищенко
,
Т
.
С
., et al. "
Новые возможности в патогенетической терапии хронической ишемии
головного мозга
."
Международный неврологический журнал
1 (2011): 37-42.
4.
Блинов
,
Д
.
В
. "
Пациенты с неврологическими расстройствами
:
обоснование необходимости
фармакоэкономической оценки оптимизации затрат на ведение с использованием
нейроспецифических
белков
в
качестве
маркеров
повышения
проницаемости
гематоэнцефалического
барьера
."
ФАРМАКОЭКОНОМИКА
.
Современная
фармакоэкономика и фармакоэпидемиология
7.1 (2014): 40-45.
5.
Камчатнов
,
П
.
Р
.,
А
.
В
.
Чугунов
, and
Н
.
А
.
Михайлова
. "
Вертебрально-базилярная
недостаточность–проблемы диагностики и терапии
."
Медицинский совет
1-2 (2013): 69-73.
